He mea paʻakikī ke wehewehe i ka makaʻu, ka hopohopo, a me ke kānalua e hele mai me ka ʻike ʻia ʻana he maʻi ʻaʻai umauma. Akā ʻo ka mea nui e pono ai ʻoe e ʻike, ua holomua nui nā lāʻau lapaʻau maʻi ʻaʻai i kēia lā. I kēia lā, e kamaʻilio mākou e pili ana i kekahi lāʻau lapaʻau hou a holomua. Ua kapa ʻia ʻo Datroway. E nānā kākou i ke ʻano o Datroway a inā hiki iā ia ke kōkua iā ʻoe.
He aha ke ʻano lāʻau lapaʻau ʻo Datroway? Pehea e hana ai?
I ka ʻōlelo maʻalahi, ʻo Datroway kahi lāʻau lapaʻau i hoʻolālā ʻia me ka hoʻohana ʻana i ka ʻenehana holomua. I ka lāʻau lapaʻau, kapa mākou i kēia he Antibody Drug Conjugate (ADC) . E noʻonoʻo iā ia he lawelawe ʻelele kūikawā. Hana ʻia kēia molekole lāʻau i ʻekolu mau ʻāpana nui.
1. Antibody: ʻO kēia ka "mea huli helu wahi" a kā mākou ʻelele. Loaʻa iā ia kahi protein kikoʻī (kahi protein i kapa ʻia ʻo Trop-2) ma luna o ka ʻili o nā hunaola kanesa a hoʻopili iā ia. ʻO kāna hana ka pepehi koho a hopu wale i nā hunaola kanesa, me ka ʻole o ka hōʻeha ʻana i nā hunaola olakino.
2. Lāʻau lapaʻau anti-cancer ( chemotherapy ): ʻO kēia ka "pūʻolo" i loko o ka mea lawe. ʻO kēia ka lāʻau lapaʻau e hoʻopau ai i nā hunaola kanesa.
3. Loulou: Hoʻohui kēia ʻāpana i ka antibody a me ka lāʻau anti-cancer. Hoʻopaʻa ʻia nā mea ʻelua i ka wā e hele ana i loko o ke koko, a laila hoʻokaʻawale ʻia ma hope o ke komo ʻana i loko o ke keʻena kanesa.
No laila, ke komo ka lāʻau Datroway i loko o ke kino, loaʻa pololei ka antibody i loko ona i nā hunaola kanesa a hoʻopili iā ia iho. A laila, ua haki kēlā mea hoʻopili, e hoʻokuʻu ana i ka lāʻau anti-cancer pololei i loko o ke hunaola kanesa. Ma kēia ʻano, ua luku ʻia ke hunaola kanesa i loko. ʻO ka pōmaikaʻi nui o kēia ʻano hana, ʻo ia ka hoʻemi nui ʻia ʻana o ka hōʻino ʻana i nā hunaola olakino.
Pehea e hāʻawi ʻia ai ka lāʻau lapaʻau Datroway?
ʻO Datroway kahi lāʻau lapaʻau i hāʻawi ʻia ma kahi haukapila, keʻena lapaʻau, a i ʻole ke kikowaena lapaʻau ma lalo o ka nānā ʻana a kāu kauka. Hāʻawi ʻia ia ma ke ʻano he wai saline ma o kahi vein (intravenous - IV infusion ) .
- Ka nui o ka lāʻau: Hoʻoholo ʻia ka nui o ka lāʻau i hāʻawi ʻia iā ʻoe e ke kaumaha o kou kino.
- Papa Kuhikuhi: Hāʻawi pinepine ʻia kēia lāʻau i kēlā me kēia ʻekolu pule . Na kāu kauka e hoʻoholo i ka nui o nā kau āu e pono ai.
- Hoʻomākaukau mua: Ma mua o ka hāʻawi ʻia ʻana o ka saline, e hāʻawi ʻia ʻoe i kekahi mau lāʻau lapaʻau ʻē aʻe e pale aku ai i ka nausea, ka luaʻi ʻana, a me nā hopena maʻi e hiki mai ana ma muli o ka saline.
- Ka manawa lapaʻau:ʻO ka lōʻihi o ka mālama mua ʻana ma kahi o 90 mau minuke. Inā ʻaʻole ʻoe e ʻike i kekahi hopena koʻikoʻi i ka manawa mua, hiki ke hāʻawi ʻia nā mālama ma hope i loko o 30 mau minuke wale nō.
- Nānā: Ma hope o nā lāʻau lapaʻau mua ʻelua, e nānā ʻia ʻoe e nā limahana lapaʻau no hoʻokahi hola ma ka liʻiliʻi. Inā ʻaʻohe pilikia, e nānā ʻia ʻoe no kahi o 30 mau minuke i nā kau ma hope a laila e ʻae ʻia e hoʻi i ka home.
Pehea e ʻike ai inā kūpono kēia lāʻau lapaʻau iaʻu?
ʻAʻole ʻo Datroway kahi lāʻau lapaʻau no nā ʻano maʻi ʻaʻai umauma āpau. E paipai wale kāu kauka i kēia lāʻau lapaʻau inā kū kāu maʻi ʻaʻai i nā kūlana aʻe:
- Pono ke kanesa he hormone receptor-positive a he HER2-negative .
- Ke hiki ʻole ke wehe loa ʻia ke kanesa me ke ʻoki ʻana (`unresectable`) a i ʻole ua pālahalaha aku i nā ʻāpana ʻē aʻe o ke kino (`metastatic`).
ʻO ka mea nui loa, i mea e kūpono ai no kēia lāʻau lapaʻau, pono ʻoe i loaʻa mua i ka lāʻau endocrine-based a me nā lāʻau chemotherapy ʻē aʻe.
No laila, ʻo ka hoʻoholo maikaʻi loa e pili ana i ka kūpono o kēia lāʻau lapaʻau iā ʻoe e hana ʻia e kāu kauka oncology e mālama nei . E nānā ʻo ia i kāu mau moʻolelo lapaʻau a pau a hoʻoholo i kēia.
Nā hopena ʻaoʻao a pehea e kaohi ai iā lākou?
E like me nā lāʻau lapaʻau maʻi kanesa, hiki iā Datroway ke hana i kekahi mau hopena ʻaoʻao. Akā ʻo ka nūhou maikaʻi, aia nā ala e hoʻokele ai i ka hapa nui o kēia mau mea. E nānā kākou i nā hopena ʻaoʻao nui a me nā mea hiki iā ʻoe ke hana e pili ana iā lākou.
| Ka hopena ʻaoʻao | Pehea e hoʻokele ai |
|---|---|
| Nā pilikia maka (Nā maka maloʻo, ʻulaʻula, ʻeha, ʻike maka pōwehiwehi) | E hoʻohana i nā kulu maka lubricating i ʻōlelo ʻia e kāu kauka ma ka liʻiliʻi he ʻehā manawa i ka lā. E pale i ke komo ʻana i nā aniani hoʻopili i ka wā o ka mālama ʻana. E haʻi koke i kāu kauka inā ʻike ʻoe i kekahi mau loli a i ʻole ka ʻoluʻolu ʻole i kou mau maka. E kuhikuhi ʻia paha ʻoe i kahi ophthalmologist. |
| ʻEha waha | E mālama i kahi pahu hau a i ʻole kahi wai hau liʻiliʻi i loko o kou waha i ka wā e hāʻawi ana i ka wai saline. E hoʻohana i ka wai holoi waha kūikawā i kuhikuhi ʻia e kāu kauka e like me ke kuhikuhi ʻana. Inā ulu a ʻoi aʻe paha kekahi mau ʻeha waha, e hoʻomaopopo koke i kāu kauka. |
| Ka luaʻi a me ka luaʻi | E lawe i ka lāʻau hoʻēmi i ka nausea i kauoha ʻia e kāu kauka i ka manawa kūpono, ma mua a ma hope o ka lāʻau lapaʻau. |
ʻO kēia nā hopena ʻaoʻao maʻamau. Inā loaʻa iā ʻoe kekahi ʻano ʻeha ʻē aʻe ma waho aʻe o kēia mau mea, mai makaʻu e kamaʻilio me kāu kauka e pili ana i ia mea.
He aha nā mea e makaʻala nui ai?
I ka wā e lawe ai i ka lāʻau lapaʻau Datroway, aia kekahi mau mea āu e makaʻala nui ai.
Nā pilikia e pili ana i ka māmā
He mea kākaʻikahi loa, hiki i kekahi poʻe ke loaʻa ka mumū o nā māmā (ʻO ka maʻi ʻōpū o ka puʻuwai) (ʻO ka maʻi ʻōpū o ka puʻuwai a i ʻole ka maʻi ʻōpū) ma muli o kēia lāʻau lapaʻau. No laila, inā loaʻa iā ʻoe nā hōʻailona e like me ke kuni, ka paʻakikī o ka hanu ʻana, ka hanu ʻana, ke kuni, a i ʻole ka ʻū ʻana o ka umauma , mai hoʻowahāwahā iā ia a e hoʻomaopopo koke i kāu kauka . Inā pono, e hoʻomaka ke kauka i ka lāʻau lapaʻau no ia.
ʻO ka hāpai ʻana a me ka kaohi hānau
He mea nui loa kēia.
- Hiki i ka lāʻau lapaʻau Datroway ke hoʻopilikia i kahi pēpē i hānau ʻole ʻia. No laila, e hoʻāʻo ʻia ʻoe e ʻike inā hāpai ʻoe ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau.
- Inā he wahine ʻoe i hiki ke hānau keiki, pono ʻoe e hoʻohana i kahi ʻano kaohi hānau kūpono loa i ka wā o ka mālama ʻana a no 7 mau mahina ma hope o ka mahele hope loa .
- Inā he kāne ʻoe a hiki i kāu hoa ke hāpai, pono ʻoe e hoʻohana i ka kaohi hānau kūpono i ka wā o ka mālama ʻana a no 4 mau mahina ma hope o ka mahele hope loa .
Inā he mau nīnau kāu e pili ana i kēia, mai kānalua e kamaʻilio me kāu kauka.
Leka Lawe-Home
- He lāʻau lapaʻau i kuhikuhi ʻia a holomua ʻo Datroway no kekahi mau ʻano maʻi ʻaʻai umauma. Ua like ia me kahi "missile alakaʻi" e ʻimi a luku i nā hunaola maʻi ʻaʻai.
- ʻAʻole kūpono kēia lāʻau lapaʻau no nā kānaka āpau. Na kāu kauka maʻi kanesa e hoʻoholo inā kūpono ia iā ʻoe.
- Hāʻawi ʻia ka lāʻau lapaʻau ma ke ʻano he wai saline ma o kahi aa koko, i hoʻokahi manawa i kēlā me kēia ʻekolu pule.
- Hiki ke loaʻa nā hopena ʻaoʻao e like me nā pilikia maka, nā ʻeha waha, a me ka luaʻi. Akā hiki ke kāohi ʻia kēia mau mea. E haʻi koke aku i kāu kauka e pili ana i kekahi ʻeha.
- Inā ʻike ʻoe i nā hōʻailona e like me ka paʻakikī o ka hanu ʻana, mai hoʻowahāwahā iā lākou. E ʻimi koke i ke kōkua lapaʻau.
- He mea nui e pale i ka hāpai ʻana i ka wā o ka mālama ʻana a no kekahi manawa ma hope o ka mālama ʻana.
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