Ua manaʻo paha ʻoe e hoʻohou mau ʻia ke koko i loko o ko kākou kino? He hale hana kupaianaha ko kākou kino. ʻO ka hana nui loa e hana ʻia ana ma kēia hale hana i ka lā a pau, ʻo ia ka hana ʻana i nā hunaola koko ʻulaʻula, ʻo ia hoʻi nā hunaola koko ʻulaʻula i loko o ke koko. Inā luhi mau ʻoe a make ke ola, ʻo ke kumu paha ka nele o ka hana ʻana i nā hunaola koko ʻulaʻula. No laila, i kēia lā e kamaʻilio mākou e pili ana i kēia kaʻina hana kupaianaha, ʻo ia hoʻi ka 'erythropoiesis'.
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I ka ʻōlelo maʻalahi, he aha ka erythropoiesis?
ʻO ka Erythropoiesis ke kaʻina hana e hana ai ko mākou kino i nā hunaola koko ʻulaʻula, a i ʻole nā erythrocytes ma ke ʻano lapaʻau. Ua like kēia me ka wā e kuke ai ko mākou makuahine i kahi meaʻai hou ke pau kā mākou meaʻai. Make nā hunaola koko ʻulaʻula kahiko i loko o ko mākou kino ma hope o kekahi manawa. No laila, ʻo kēia kaʻina hana ka mea e hana ai i nā hunaola koko ʻulaʻula hou.
Mālama kēia i ka helu o nā hunaola koko ʻulaʻula i loko o ko mākou kino i kahi pae kūpono, ʻaʻole e hoʻonui a i ʻole e emi nui ana.
No laila no ke aha he mea nui nā hunaola koko ʻulaʻula iā mākou?
E noʻonoʻo i kahi lawelawe lawe e lawe ana i nā waiwai ma kou kino holoʻokoʻa. Hana nā hunaola koko ʻulaʻula i kēlā.
- Ka Hoʻouna ʻana i ka Oxygen: Ke hanu mākou, lawe ʻia ka oxygen e komo ana i loko o ko mākou mau māmā i kēlā me kēia cell a me nā ʻiʻo i loko o ko mākou kino e kēia mau hunaola koko ʻulaʻula. Mai ka lolo a i nā manamana wāwae, pono nā mea āpau i ka oxygen e ola ai.
- Ka wehe ʻana i ke kalapona ʻokikene: Eia kekahi, ʻo ke kalapona ʻokikene, kahi huahana ʻōpala i hoʻokuʻu ʻia mai ko mākou mau pūnaewele, ua hōʻiliʻili ʻia a hoʻihoʻi ʻia i nā māmā i hiki iā mākou ke wehe iā ia mai ke kino ke hanu mākou.
I ka ʻōlelo maʻalahi, me ka ʻole o nā hunaola koko ʻulaʻula, ʻaʻole hiki i ko mākou mau hunaola kino ke ola.
ʻO ka Erythropoiesis kekahi ʻāpana wale nō o ke kaʻina hana holoʻokoʻa o ke kūkulu ʻana i ke koko i loko o ko kākou kino, i kapa ʻia ʻo 'hematopoiesis.' Hoʻopuka kēia kaʻina hana holoʻokoʻa i nā ʻano ʻekolu o nā hunaola koko: nā hunaola koko ʻulaʻula, nā hunaola koko keʻokeʻo, a me nā platelets.
Ma hea kahi e hana ʻia ai kēia kaʻina hana i loko o ke kino?
Loli kahi i hana ʻia ai kēia mau hunaola koko ʻulaʻula i ka hala ʻana o ka manawa.
ʻOiai he pēpē i loko o ka ʻōpū (Fetal Erythropoiesis)
Hoʻomaka ke koko e hana ʻia i loko o ko kākou kino ma mua o ko kākou hānau ʻia ʻana.
- I 3 pule: Hoʻomaka ke koko e hana i loko o ka ʻano i kapa ʻia ʻo 'yolk sac', ka mea e hāʻawi i ka embryo me kāna meaʻai mua.
- I ka hala ʻana o 2-3 mahina: Hoʻomaka ke koko i loko o ke akepaʻa a me ka spleen o ke keiki.
- Ma hope o 5 mau mahina: Hoʻomaka ke koko e hana i loko o ka iwi iwi o ka pēpē i loko o ka ʻōpū.
Nā keiki a me nā mākua
Ma hope o ko kākou hānau ʻia ʻana, lilo ko kākou iwi iwi i hale hana nui no ka hana ʻana i nā hunaola koko ʻulaʻula. ʻO kēia ka ʻāpana palupalu a huʻahuʻa i loko o ko kākou mau iwi.
- I ka wā kamaliʻi: Hana ʻia ke koko mai ka iwi o nā iwi nui o ke kino.
- I ka wā makua: Hana ʻia ke koko ma ka iwi iwi o kekahi mau iwi kikoʻī , e like me nā iwi ʻūhā, nā iwi kuamoʻo o ka iwi kuamoʻo, nā iwi ʻaoʻao, a me ka iwi pālahalaha ma waenakonu o ka umauma (iwi umauma).
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Check Availability →Ka huakaʻi o kahi hunaola koko ʻulaʻula
ʻAʻole kēia e hana koke ʻia. Pono kahi hunaola koko ʻulaʻula hoʻokahi e hele i kekahi mau pae e oʻo piha ai, ʻo ia hoʻi, e hana pono. ʻO ka huakaʻi holoʻokoʻa e lawe ʻia ma kahi o hoʻokahi pule .
Hoʻomaka ia me kahi pūnaewele kūikawā i kapa ʻia ʻo 'Hematopoietic Stem Cell' (HSC). Ua like kēia me kahi hua. Hiki i kēia hua ke ulu i nā mea āpau mai nā hunaola koko ʻulaʻula, nā hunaola koko keʻokeʻo, a me nā platelets. I mea e lilo ai i hunaola koko ʻulaʻula, hele kēia hunaola kumu ma o kekahi mau pae.
Hiki i ka papa ma lalo nei ke kōkua iā ʻoe e hoʻomaopopo pono i kēia huakaʻi.
| Kahua | He wehewehe maʻalahi |
|---|---|
| Kelepona kumu (Hematopoietic Stem Cell - HSC) | ʻO kēia ke kumu o kēlā me kēia hunaola koko, e like me ka hua e ulu mai ai kahi mea kanu. |
| Proerythroblast | ʻO ke kaʻina hana mua loa i ka huakaʻi e lilo ai i ke koko koko ʻulaʻula. |
| ʻEritroblasta | Hoʻemi mālie ke kelepona a hoʻomaka e hana i ka hemoglobin, ka protein e lawe ana i ka oxygen. |
| ʻO Normoblast | I loko o kēia kahua, ua wehe ʻia ka nucleus o ke kelepona, e ʻae ana i ke kelepona e hoʻopiha me ka hemoglobin hou aʻe. |
| ʻO ka Reticulocyte | He mau hunaola koko ʻulaʻula ʻōpiopio kēia. ʻO kēia ka manawa e hoʻokuʻu ʻia ai lākou mai ka iwi iwi i loko o ke koko. |
| Nā ʻEritrosit | He hunaola koko ʻulaʻula i oʻo piha, mākaukau e lawe i ka oxygen. |
ʻO ke ola o kahi hunaola koko ʻulaʻula i hana ʻia ma kēia ʻano he 120 mau lā . E like me ka pila, make kēia mau hunaola ma hope o 120 mau lā o ka hoʻohana ʻana. ʻO ia ke kumu e pono ai ko mākou kino e hana mau i nā hunaola koko ʻulaʻula hou.
Pehea e ʻike ai ke kino pehea e hana ai i ke koko?
He ʻōnaehana hoʻomalu kupaianaha loa kēia. Hoʻomalu ko mākou kino i ka hana ʻana o nā hunaola koko ʻulaʻula ma muli o ka pae o ka oxygen i loko o ke kino.
E noʻonoʻo ʻoe e hele ana ʻoe i kahi ʻāina mauna kiʻekiʻe e like me Nuwara Eliya. I kou piʻi ʻana i luna, manaʻo ʻoe he paʻakikī iki ka hanu ʻana, ʻeā? No ka mea, ua haʻahaʻa ka nui o ka oxygen i ka lewa. A laila, ua lawa ʻole ka nui o ka oxygen e hiki aku ana i ko kākou kino. Kāhea mākou i kēia ʻano he hypoxia .
ʻO kēia ka manawa e hoʻāla ʻia ai ko kākou mau puʻupaʻa .
ʻO nā puʻupaʻa nā mea e nānā mau ana i nā pae oxygen i loko o ko kākou koko. Ke ʻike lākou ua haʻahaʻa nā pae oxygen, hoʻokuʻu nā puʻupaʻa i kahi hormone kūikawā (ʻelele kemika) i kapa ʻia ʻo Erythropoietin (EPO) i loko o ke koko.
Eia ke ʻano o ka hana ʻana o kēia kaʻina hana:
1. ʻAʻole lawa ka oxygen i kou mau ʻiʻo.
2. I ka pane ʻana i kēlā 'hōʻailona', hoʻokuʻu nā puʻupaʻa i ka nui o ka hormone (EPO).
3. Hele kēia hormone (EPO) ma o ke koko a "kamaʻilio" me ka iwi ʻiʻo, me ka ʻōlelo ʻana, "E wikiwiki, e hana i nā hunaola koko ʻulaʻula hou aku!"
4. Hoʻolalelale i ka hana ʻana o nā hunaola koko ʻulaʻula i loko o ka iwi ʻiʻo.
5. Hoʻihoʻi nā hunaola koko ʻulaʻula i hana hou ʻia i ka pae oxygen i loko o ke koko i ka maʻamau.
6. Ke hoʻi hou ka pae o ka oxygen i ka maʻamau, hoʻemi nā puʻupaʻa i ka hoʻokuʻu ʻana o EPO.
He maikaʻi loa ko kākou kino i ka mālama ʻana i nā mea āpau i ke kaulike (homeostasis) ma kēia ʻano. Mālama lākou i ka pae kūpono, ʻaʻole e ʻae iā ia e piʻi nui aʻe a ʻaʻole hoʻi e haʻahaʻa loa.
He aha ka mea e hana ʻia inā hele hewa kēia kaʻina hana?
I kekahi manawa hiki ke hele hewa kēia kaʻina hana o ka hana ʻana i nā hunaola koko ʻulaʻula. A laila hiki ke kū mai nā pilikia nui ʻelua. ʻO ka liʻiliʻi o nā hunaola koko ʻulaʻula i hana ʻia, a i ʻole he nui loa i hana ʻia.
| Kūlana | ʻO ke ʻano maʻalahi | ʻAno/ʻano i hoʻopilikia ʻia |
|---|---|---|
| Anemia | Ka helu haʻahaʻa o nā hunaola koko ʻulaʻula (anemia). | Ua nalowale ke kino i nā hunaola koko ʻulaʻula e lawe i ka oxygen. Hiki i kēia ke hana i nā hōʻailona e like me ka luhi pinepine, ka nāwaliwali, ka maeʻele, ka pōkole o ka hanu, a me ke anuanu ʻē . |
| ʻEritrositosis | Hoʻonui ʻia ka helu o nā hunaola koko ʻulaʻula (hoʻonui ʻia ka mānoanoa o ke koko). | I ka mānoanoa ʻana o ke koko, hiki ke keakea ʻia ke kahe ʻana o ke koko. Hiki ke loaʻa nā hōʻailona e like me ke poʻo ʻeha, ka luhi, a me ka poniuniu . I kekahi mau hihia, aia kahi pilikia o nā ʻōpū koko weliweli . |
Inā loaʻa iā ʻoe nā hōʻailona e like me kēia, he mea nui loa ia e ʻike i ke kauka a ʻimi i ka ʻōlelo aʻo me ka ʻole o ka hoʻoholo ʻana i kāu iho.
Nā mea e hiki ke hoʻopilikia i ka hana ʻana o nā cell koko ʻulaʻula
Hiki ke hoʻopili ʻia kēia kaʻina hana e nā ʻano maʻi like ʻole a me nā kumu ʻē aʻe.
Nā maʻi e pili ana i ka māmā
Ke loaʻa iā ʻoe nā maʻi hanu lōʻihi e like me ka hānō a me ka COPD, e emi ana ka nui o ka oxygen i loaʻa i kou kino. Hoʻāʻo ke kino e hana i nā hunaola koko ʻulaʻula hou aʻe e hoʻoponopono ai.
Nā maʻi ʻaʻai koko a me ka iwi
I nā maʻi kanesa e like me ka leukemia a me ka lymphoma, ua hoʻopilikia ʻia ka hana maʻamau o ka iwi iwi. ʻO ka hopena, e emi paha ka hana ʻana o nā hunaola koko ʻulaʻula a i ʻole e hana ʻia nā hunaola ʻē.
Nā kumu ʻē aʻe
- Nā hemahema o ka meaʻai: No ka hana ʻana i ke koko maikaʻi, pono ʻoe i nā meaʻai maikaʻi. ʻO ka hao, ka huaora B12, a me ka folate nā meaʻai koʻikoʻi. Inā ʻaʻole ʻoe e loaʻa i ka lawa o kēia mau mea ma o kāu ʻai ʻana, ʻaʻole hiki i kou kino ke hana pono i nā hunaola koko ʻulaʻula, e alakaʻi ana i ka anemia.
- Maʻi puʻupaʻa:Ma muli o ka hana ʻia ʻana o ka hormone (EPO) e nā puʻupaʻa, inā hōʻino ʻia nā puʻupaʻa, e emi iho paha ka hana ʻana o (EPO) a e hōʻino ʻia paha ka hana ʻana o nā hunaola koko ʻulaʻula.
Leka Lawe-Home
- ʻO ke kaʻina hana o ka hana ʻana i nā hunaola koko ʻulaʻula, a i ʻole erythropoiesis, he mea kupaianaha ia e hana mau ana a hana aunoa ʻia i loko o ko kākou kino.
- Hoʻokele nui ʻia kēia kaʻina hana e kahi hormone i kapa ʻia ʻo EPO, kahi i hoʻokuʻu ʻia e nā puʻupaʻa.
- Inā ʻoe e ʻike mau nei i nā hōʻailona e like me ka luhi, ka mae, a me ka pōkole o ka hanu, he hōʻailona paha ia o ka anemia . I kēlā hihia, e ʻike pono i kāu kauka no ka ʻōlelo aʻo.
- He mea nui loa ka ʻai ʻana i ka meaʻai kaulike i waiwai i ka hao (ʻiʻo, iʻa, legumes, spinach), wikamina B12 (waiū, hua manu), a me ka folate (nā mea kanu ʻōmaʻomaʻo, legumes) no ka mālama ʻana i nā pae koko ʻulaʻula olakino.
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