Ua ʻike anei ʻoe e pili ana i nā kīʻaha koko 'windowed' liʻiliʻi (fenestrated capillaries) i loko o ko kākou kino?

Ua like ko kākou kino me kahi mīkini kupaianaha, ʻeā? ʻO ka ʻōnaehana alaloa i loko o kēia mīkini, ʻo ia ko kākou mau kīʻaha koko. ʻOiai ua lohe mākou e pili ana i nā alanui nui e like me nā aʻa a me nā veins, ua ʻike anei ʻoe e pili ana i ka pūnaewele o nā alanui ʻaoʻao liʻiliʻi loa i loko o kēia ʻōnaehana i aneane ʻike ʻole ʻia e ka maka ʻōlohelohe? Kāhea mākou i kēia mau capillaries. I kēia lā e kamaʻilio mākou e pili ana i kahi ʻano capillary kūikawā, kahi ʻano capillary me nā puka makani liʻiliʻi.

He aha kēia mau capillaries 'windowed' (Fenestrated Capillaries)?

I ka ʻōlelo maʻalahi, he ʻano capillary kēia i loko o kā mākou ʻōnaehana kīʻaha koko nona nā lua liʻiliʻi loa a i ʻole nā ​​​​​​puka e like me ka puka makani. ʻO "fenestrae" ma ka ʻōlelo Latina ʻo ia hoʻi "nā puka makani," no laila ua loaʻa ka inoa mai ia manaʻo.

Ma mua o ka ʻae ʻana i nā mea e hele ma waena o nā capillaries maʻamau, hiki i kēia mau capillaries 'windowed' ke ʻae i nā ʻāpana nui, e like me nā protein, e hele mai ke koko i loko o nā ʻōpū a me nā glands. E noʻonoʻo e like me ka hoʻohana ʻana i kahi mesh me nā lua nui iki ma kahi o kahi mesh maʻamau. ʻAe kēia i ka hoʻololi ʻana o nā mea me ka ʻoi aku ka maikaʻi a me ka wikiwiki.

He aha ka hana nui o kēia mau mea? No ke aha lākou i koʻikoʻi ai?

Kōkua kēia mau capillaries i ka lawe ʻana i ke koko, nā wai, a me nā ʻōpala ma loko o ko kākou kino, akā ʻo kā lākou hana nui loa, ʻo ia ka hana ʻana o nā puʻupaʻa .

E noʻonoʻo i ko kākou mau puʻupaʻa ma ke ʻano he ʻōnaehana kānana holomua loa i loko o ke kino. ʻO ka ʻāpana nui o kēia kānana i kapa ʻia ʻo ka glomerulus . ʻO kēia glomerulus he mea ʻē aʻe ia ma mua o kahi pōpō liʻiliʻi o ke kaula i hana ʻia me kēlā mau capillaries puka makani a mākou i kamaʻilio ai. Ua like ia me kahi kānana kī.

I ka hele ʻana o ke koko ma o kēia pōpō kaula, ua kānana ʻia nā huahana ʻōpala a me ka wai keu ma o kēlā mau puka makani liʻiliʻi. Eia nō naʻe, ʻo nā mea nui e pono ai ke kino, e like me nā protein a me nā hunaola koko ʻulaʻula, e noho mau ana i loko o ke koko. ʻO nā huahana ʻōpala i kānana ʻia ma kēia ʻano e hoʻokuʻu ʻia mai ke kino ma ke ʻano he mimi.

No laila, ke maopopo nei iā ʻoe? Hiki i ko kākou mau puʻupaʻa ke hoʻomaʻemaʻe pono i ke koko a wehe i nā huahana ʻōpala ma muli o nā 'puka makani' kūikawā i loko o kēia mau Fenestrated Capillaries.

Hoʻopuni pū kēia mau capillaries i nā tubules renal. Ma o lākou, hoʻihoʻi ʻia nā meaʻai e pono ai ke kino mai nā mea i kānana ʻia i loko o ke koko. No laila, he mea nui lākou no ka hana olakino o nā puʻupaʻa.

Aia ma hea kēia mau mea i loko o ko kākou kino?

Aia kēia mau capillaries kūikawā ma nā wahi e pono ai ka metabolism o ke kino e hana wikiwiki a me ka pono. E nānā kākou i kēlā mau wahi koʻikoʻi.

He aha nā maʻi e hoʻopilikia ai i kēia mau capillaries?

Ke hōʻino ʻia kēia mau kīʻaha koko liʻiliʻi, hiki ke hoʻopilikia pololei ʻia ka hana o nā ʻōkana pili.

Nā maʻi e pili ana i ka puʻupaʻa

Hiki i nā kānaka me ka maʻi puʻupaʻa mau loa (CKD) ke hōʻino ʻia kēia mau capillaries. ʻOi aku ka lahilahi o ka pūnaewele o nā capillaries a puni nā tubules renal a emi ka paʻa. Ua kapa ʻia kēia ʻo 'capillary rarefaction'. Ke hana ʻia kēia, ʻaʻole hiki i nā puʻupaʻa ke hana pono a hiki ke loaʻa nā pilikia olakino ʻē aʻe e like me ke koko kiʻekiʻe (Hypertension).

Eia kekahi, ʻo nā maʻi e like me ka glomerulonephritis , kahi mumū o nā glomeruli, hiki ke hoʻopilikia i ke kaʻina kānana holoʻokoʻa o nā puʻupaʻa. Inā ʻaʻole mālama koke ʻia kēlā mau maʻi puʻupaʻa, hiki iā lākou ke holomua i ka hāʻule ʻana o nā puʻupaʻa.

He kūlana kakaikahi loa akā koʻikoʻi

ʻO ka Syndrome Leak Capillary Systemic (SCLS)He kūlana laha ʻole loa kēia a he mea hoʻoweliweli paha i ke ola. Hana ʻia kēia i ka wā e hōʻino ʻia ai nā paia o nā capillaries, e hoʻokahe ana i ka nui o ke wai mai nā kīʻaha koko i loko o nā ʻiʻo a puni. Hiki i kēia ke hoʻohaʻahaʻa koke i kou koko i kahi haʻahaʻa loa. Akā e hoʻomanaʻo, he kūlana laha ʻole loa kēia.

No laila pehea mākou e mālama ai i kēia mau kīʻaha koko liʻiliʻi i ke olakino?

ʻAʻohe mea kūikawā e hana ai e pili ana i kēia. ʻO ka mea maikaʻi loa, ʻo ia ka mālama ʻana i ke olakino maikaʻi holoʻokoʻa. No ka mea, ʻo kēia mau capillaries kekahi ʻāpana o kā mākou ʻōnaehana hoʻopuni koko. No laila, inā olakino ka ʻōnaehana holoʻokoʻa, olakino nō hoʻi kēia mau aa liʻiliʻi.

Eia kekahi mau mea hiki iā ʻoe ke hana:

• E hoʻoikaika kino mau: E hoʻokō i kahi nohona hana ikaika.
• E ʻai i ka ʻai kaulike: E ʻai i nā huaʻai a me nā mea kanu hou aʻe. E hōʻemi i ka waiʻona. E koho i nā meaʻai olakino no ka puʻuwai.
• E mālama i ke kaumaha olakino: E mālama i ke kaumaha kūpono i kou kiʻekiʻe. Inā ʻoe he momona loa, e hoʻāʻo e hoʻemi i ke kaumaha.
• E mālama i nā maʻi mau loa: Inā loaʻa iā ʻoe nā maʻi e like me ka maʻi diabetes a i ʻole ke koko kiʻekiʻe, e mālama pono iā lākou e like me nā kuhikuhi a kāu kauka.
• E pale loa i ka puhipaka: He mea ʻino loa ka puhipaka i nā kīʻaha koko.

Āhea wau e ʻike ai i ke kauka?

He mea nui loa e ʻike i kāu kauka ʻohana inā ʻike ʻoe i kekahi mau loli i kou kino, ʻoiai inā he mau hōʻailona kou e pili ana i ka maʻi puʻupaʻa.