Ke ʻike nei ʻoe i nā pae kiʻekiʻe o ka methotrexate i loko o kou kino a ua nāwaliwali kou mau puʻupaʻa? A laila e aʻo kākou e pili ana i kēia lāʻau pale Glucarpidase!

Ke noʻonoʻo nei paha ʻoe, "Auē, he aha ke ʻano o ka lāʻau lapaʻau ʻē aʻu e kamaʻilio nei?" ʻAe, he ʻano lāʻau lapaʻau kūikawā kēia. I kekahi manawa, ke nui loa ka lāʻau lapaʻau i kapa ʻia ʻo Methotrexate, ka mea i hoʻohana ʻia e mālama i nā maʻi e like me ke kanesa, e hōʻiliʻili i loko o ke kino, hiki iā ia ke hana i nā pilikia, ʻoiai inā ʻaʻole hana pono kou mau puʻupaʻa. ʻO ia ka manawa e hiki mai ai kēia inikini i kapa ʻia ʻo Glucarpidase i ko mākou hoʻopakele. E kamaʻilio hou anei kākou e pili ana i kēia?

He aha kēia lāʻau lapaʻau i kapa ʻia ʻo Glucarpidase? I ka pōkole...

E noʻonoʻo e like me kahi superhero liʻiliʻi, ʻo Glucarpidase . He enzyme maoli nō ia. Ua like nā enzyme me nā mea kōkua liʻiliʻi e wikiwiki a kōkua i nā kaʻina hana kemika like ʻole i loko o ko mākou kino. No laila, ʻo ka mea a kēia enzyme i kapa ʻia ʻo Glucarpidase e hana ai, ʻo ia ka hoʻemi ʻana i ka nui o kēlā lāʻau i kapa ʻia ʻo Methotrexate aʻu i ʻōlelo ai ma mua i loko o ko mākou kino.

I kēia manawa ke nīnau nei ʻoe, "No ke aha e hōʻemi ai i ka methotrexate? ʻAʻole anei he lāʻau lapaʻau kēlā?" ʻAe, he lāʻau lapaʻau koʻikoʻi loa ka methotrexate a ikaika hoʻi i hāʻawi ʻia e kāohi i ka ulu ʻana o nā hunaola kanesa a no nā kūlana e like me ka rumatika. Eia naʻe, hoʻokuʻu nui ʻia kēia lāʻau lapaʻau mai ke kino ma o nā puʻupaʻa. No laila, inā nāwaliwali iki nā puʻupaʻa o kekahi, inā ʻaʻole lākou e hana pono ana, hoʻokuʻu mālie ʻia kēia methotrexate mai ke kino. A laila ʻo ka mea e hana ʻia, ʻo ia ka hōʻiliʻili ʻana i loko o ke kino a hiki i nā pae ʻawahia . He mea weliweli kēlā. ʻO ia ka manawa e hāʻawi ʻia ai kēia inikini kūikawā i kapa ʻia ʻo glucarpidase, hoʻemi koke ʻia ka methotrexate keu i hōʻiliʻili ʻia i loko o ke kino, a pale ʻia ka mea maʻi.

Hiki paha iā ʻoe ke loaʻa kēia lāʻau lapaʻau ma lalo o ka inoa inoa VORAXAZE , akā ʻo kāu kauka wale nō ke ʻike pono inā pono ʻoe a ʻaʻole paha.

Iā wai kēia lāʻau Glucarpidase i hāʻawi ʻia ai?

ʻAʻole kēia he lāʻau lapaʻau no nā mea āpau. He mea kōkua nui ia no:

• ʻO ka lāʻau lapaʻau methotrexate no ka poʻe i hōʻea i nā pae ʻawahia weliweli i loko o ko lākou kino.
• Eia kekahi, pono e hana maikaʻi ʻole ko lākou mau puʻupaʻa , no ka mea, inā hana maikaʻi nā puʻupaʻa, hoʻokuʻu pinepine ʻia ka methotrexate mai ke kino mai.

Hiki ke hāʻawi ʻia kēia lāʻau lapaʻau i nā pākeke a me nā keiki . I kekahi manawa, hiki ke hoʻohana ʻia i nā hihia kūikawā, ʻoiai no nā pēpē e like me hoʻokahi mahina. Eia nō naʻe, i ka hāʻawi ʻana iā ia i nā keiki liʻiliʻi, hoʻohana pono nā kauka iā ia a e like me nā kuhikuhi kūikawā . No laila, inā ʻoe e kamaʻilio nei me kāu keiki e pili ana i kēia lāʻau lapaʻau, ʻoi aku ka maikaʻi o ke kamaʻilio pono ʻana me ke kauka e pili ana i ia mea a wehewehe i nā mea āpau.

He aha nā mea nui e pono iaʻu e haʻi aku i ke kauka ma mua o ka hoʻohana ʻana i kēia lāʻau lapaʻau?

Ma mua o ka hāʻawi ʻia ʻana o kēia lāʻau pale Glucarpidase iā ʻoe a i ʻole kekahi āu i ʻike ai, eia kekahi mau mea āu e haʻi aku ai i kāu hui lapaʻau (e like me nā kauka a me nā kahu maʻi):He nui nā mea. ʻAʻole ia he manaʻo maikaʻi e hūnā i kēia mau mea, no ka mea, he pilikia palekana paha ia nou.

• Inā loaʻa iā ʻoe kekahi mau maʻi allergies:
• Inā he maʻi ʻoe i kēia lāʻau glucoparidase.
• Inā loaʻa iā ʻoe kekahi mau maʻi ʻaleka i nā lāʻau lapaʻau ʻē aʻe, nā meaʻai, nā kala, a i ʻole nā ​​mea mālama, e haʻi i kāu kauka. I kekahi manawa, hiki i kahi maʻi ʻaleka i kekahi mea ke hoʻopilikia i kekahi.
• Inā hāpai ʻoe a i ʻole e hoʻāʻo ana e hāpai: He mea nui loa kēia no ka mea hiki i kekahi mau lāʻau lapaʻau ke hoʻopilikia i ka pēpē.
• Inā he makuahine hānai ʻoe: Hiki i kekahi mau lāʻau lapaʻau ke hele i ka pēpē ma o ka waiū umauma, no laila he mea nui e haʻi i kāu kauka e pili ana i kēia.

E hoʻomanaʻo: ʻO ka haʻi ʻana i kāu kauka i ka ʻoiaʻiʻo holoʻokoʻa e pili ana i kāu ʻike olakino e kōkua nui iā ʻoe e loaʻa ka lāʻau palekana a kūpono.

Pehea ʻoe e hāʻawi ai i kēia lāʻau lapaʻau?

ʻAʻole hiki iā ʻoe ke lawe i ka home a inu a i ʻole e hoʻokomo iā ʻoe iho me kēia lāʻau i kapa ʻia ʻo Glucarpidase.

• He inikini kēia i loko o kahi aa . I ka pololei, hāʻawi ʻia kēia lāʻau lapaʻau i loko o ke kino ma o kahi aa, e like me ka hāʻawi ʻana i ka saline.
• Hāʻawi ʻia kēia e kekahi loea mālama ola i aʻo ʻia ma kahi haukapila a i ʻole ke keʻena lapaʻau . ʻO ke ʻano kēia, hana ʻia e ke kauka a i ʻole kahi kahu maʻi i aʻo kūikawā ʻia.

He aha ka mea e hana ai inā lawe nui ʻoe? (Overdosage):

ʻOiai ua hāʻawi ʻia kēia lāʻau lapaʻau ma kahi haukapila ma lalo o ka nānā ʻana o ke kauka, he mea kakaikahi loa ka overdose. Eia nō naʻe, inā manaʻo ʻoe ua hana ʻia kēia, ʻo ia hoʻi, inā manaʻo ʻoe ua hoʻonui ʻia ka nui o ka lāʻau lapaʻau, pono ʻoe e hoʻomaopopo koke i ke kikowaena kaohi lāʻau make a i ʻole ke keʻena pilikia.

Hoʻomaopopo koʻikoʻi: Ua kuhikuhi kūikawā ʻia kēia lāʻau lapaʻau nou . Na kāu kauka e kuhikuhi iā ia nou ma muli o nā kumu he nui, e like me kou kūlana olakino, nā pae methotrexate, a me ka hana o nā puʻupaʻa. No laila, mai hāʻawi a kaʻana like paha i kēia lāʻau lapaʻau me kekahi.

He aha inā e hala wau i kahi lāʻau?:

ʻOiai he lāʻau lapaʻau kēia i hāʻawi ʻia ma ka haukapila, ʻaʻohe mea nui inā hala ʻoe i kahi lā palena. Na ke kime lapaʻau e mālama i kēlā.

He aha nā mea ʻē aʻe e hiki ke launa pū me kēia lāʻau lapaʻau?

Hiki i kekahi mau lāʻau lapaʻau ke "hoʻopilikia" i nā mea ʻē aʻe a mākou e lawe ai. ʻO ia hoʻi, hiki i ka hana a kekahi ke hoʻopilikia i ka hana a kekahi. ʻO ka mea nui i ʻike ʻia a hiki i kēia manawa e hiki ke hoʻopilikia i ka glucarpidase he lāʻau lapaʻau i kapa ʻia ʻo Leucovorin .

ʻO Leucovorin kekahi lāʻau koʻikoʻi i hoʻohana ʻia i ka mālama ʻana i ka methotrexate. Kōkua ia i ka hōʻemi ʻana i nā hopena ʻaoʻao o ka methotrexate. No laila, i ka hāʻawi ʻana i ka glucoparidase a me ka leucovorin, makaʻala loa nā kauka e pili ana i ka manawa a me ka nui. No ka mea, i ka wā e hōʻemi ai ka glucoparidase i nā pae methotrexate, hiki iā ia ke hoʻopilikia i ka pono o ka leucovorin.

Eia naʻe, ʻaʻole i piha kēia papa inoa. E haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe ai (i kauoha ʻia a kūʻai ʻia paha ma luna o ke kūʻai), nā mea kanu, nā huaora (nā mea hoʻohui meaʻai), a inā ʻoe e puhipaka, inu waiʻona, a hoʻohana paha i nā lāʻau lapaʻau ʻē aʻe i kū ʻole i ke kānāwai. I kekahi manawa, hiki i nā mea i manaʻo ʻole ʻia ke launa pū me kāu mau lāʻau lapaʻau.

He aha nā mea e pono ai kākou e makaʻala nui ai i ka wā e lawe ai i ka lāʻau lapaʻau?

Ke loaʻa iā ʻoe kēia inikini Glucarpidase, e nānā pono ke kime lapaʻau iā ʻoe . ʻO ke ʻano kēia e nānā mau lākou i kou kūlana.

• Nā hoʻāʻo koko: Pono ʻoe e loaʻa i nā hoʻāʻo koko maʻamau i ka wā e lawe ana i kēia lāʻau lapaʻau. ʻIke anei ʻoe i ke kumu? ʻO ka mea nui, ʻo ia ke nānā i ka haʻahaʻa o kāu mau pae methotrexate . Hiki i kēia mau hoʻāʻo koko ke nānā i kāu hana puʻupaʻa a me nā mea nui ʻē aʻe. Penei ke hoʻoholo ai nā kauka inā e hana ana ka lāʻau lapaʻau a inā pono e hana ʻia kekahi mea ʻē aʻe.
• Pōniuniu: Hiki i kekahi poʻe ke manaʻo iki i ka pōniuniu ma hope o ka lawe ʻana i kēia lāʻau. No laila, a hiki i kou ʻike pono ʻana i ke ʻano o ka hopena o kēia lāʻau iā ʻoe, e pale i ka hoʻokele kaʻa ʻana, ka hana ʻana me nā mīkini, a i ʻole ka hana ʻana i nā hana ʻē aʻe e pono ai ʻoe e makaʻala loa .
• E makaʻala i ke ala koke ʻana: Ke ala ʻoe mai kahi noho a moe paha, mai ala koke, akā, e ala mālie . He mea nui loa kēia inā he ʻelemakule ʻoe. A i ʻole, e manaʻo paha ʻoe ua poniuniu a hāʻule.
• E pale i ka waiʻona: Hiki i ka inu ʻana i ka waiʻona ke hoʻonui i kou poniuniu. No laila, ʻoi aku ka maikaʻi o ka pale ʻana i ka waiʻona i ka wā e lawe ana i kēia lāʻau.

He aha nā hopena ʻaoʻao e hiki ke loaʻa mai kēia lāʻau lapaʻau?

E like me nā lāʻau lapaʻau āpau, hiki i ka Glucarpidase ke hana i kekahi mau hopena ʻaoʻao. Akā, ʻaʻole i loaʻa i nā kānaka a pau. Loaʻa wale nō i kekahi poʻe. Mai hopohopo, akā he mea nui e makaʻala i kēia mau mea.

Nā hopena ʻaoʻao e pono ʻoe e haʻi koke aku i kāu kauka :

Inā ʻike ʻoe i kekahi o kēia mau hōʻailona, ​​​​pono ʻoe e haʻi koke aku i kāu kauka a i ʻole kekahi loea lapaʻau me ka hoʻokaʻulua ʻole.

• Nā hopena alerika:
• ʻŌhū ʻili
• ʻO ka maneʻo a i ʻole ka hives
• Ka pehu ʻana o ka maka, nā lehelehe, a i ʻole ke alelo - He mea weliweli loa kēia no ka mea hiki ke pilikia i ka hanu ʻana.
• Nā loli i ka ʻike: Ka pohihihi koke ʻana o ka ʻike, nā loli e like me ka ʻike ʻana ma nā ʻāpana ʻelua.
• ʻEha, ʻūlū, mae wale i nā lima a i ʻole nā ​​wāwae: He manaʻo e like me ka hiamoe ʻana o ka lālā, a he ʻeha ʻoi wale nō paha.
• Haʻalulu: Haʻalulu hiki ʻole ke kāohi ʻia o nā lālā.

Nā hopena ʻaoʻao ʻaʻole i koʻikoʻi pinepine, akā pono e hōʻike i kāu kauka inā hoʻomau lākou:

E nalo pinepine kēia mau mea ma hope o kekahi mau lā. Eia nō naʻe, inā hoʻomau lākou a hoʻopilikia paha iā ʻoe, e haʻi i kāu kauka .

• Ka maʻi kahe: Ke hele ʻana o ka ʻōpala.
• Pōniuniu: He manaʻo e milo ana i loko o ke poʻo.
• ʻUlaʻula o ka maka: ʻUlaʻula koke o ka maka a me ka manaʻo o ka wela e pālahalaha ana mai ia mea.
• ʻEha poʻo : ʻEha poʻo.
• Ka luaʻi, ka luaʻi ʻana: Manaʻo ʻeha kou ʻōpū, me he mea lā e luaʻi ana ʻoe.

ʻAʻole kēia papa inoa i nā hopena ʻaoʻao āpau. Inā ʻike ʻoe i kekahi mea ʻē aʻe i ʻike ʻole ʻia, e kamaʻilio me kāu kauka e pili ana i ia mea. I kekahi manawa ʻaʻole paha ma muli o ka lāʻau lapaʻau, akā maikaʻi ke makaʻala.

Ma hea ʻoe e mālama ai i ka lāʻau lapaʻau?

ʻAʻole pono ʻoe e hopohopo no kēia. No ka mea, ʻaʻole ʻoe e ʻae ʻia e lawe i kēia lāʻau pale Glucarpidase i ka home. Hoʻohana ʻia ia ma kahi haukapila a i ʻole ke keʻena lapaʻau. No laila, e mālama nā limahana lapaʻau i ka mālama pono ʻana.

ʻO ka mea nui loa āu e hoʻomanaʻo ai (Leka Lawe-Home)

ʻAe, no laila, mai nā mea a mākou i kamaʻilio ai, eia nā mea nui loa e pono ai ʻoe e hoʻomanaʻo:

• He enzyme kūikawā ka Glucarpidase i hāʻawi ʻia i ka wā e piʻi ai ka pae ʻawahia o ka lāʻau Methotrexate i loko o ke kino, ʻoiai hoʻi i ka poʻe i hana pono ʻole ko lākou mau puʻupaʻa.
• Hāʻawi ʻia kēia ma ke ʻano he inikini i loko o kahi aʻa koko , ma ka haukapila, e kekahi loea lapaʻau i aʻo ʻia.
• He mea nui e haʻi aku i kāu kauka e pili ana i nā maʻi allergies āu e loaʻa nei, inā ʻoe e hāpai ana a hānai waiū paha, a e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei .
• ʻOiai ʻoe e lawe ana i ka lāʻau lapaʻau, e nānā pono ʻia ʻoe a e hana ʻia nā hoʻāʻo koko.
• E makaʻala no ka mea hiki ke hiki mai ka poniuniu a me nā mea ʻē aʻe.
• Inā loaʻa iā ʻoe kekahi mau hopena ʻaoʻao koʻikoʻi , e haʻi koke aku i kāu kauka .
• He lāʻau lapaʻau kūikawā kēia, no laila e kamaʻilio me ke kauka a wehewehe i nā mea āpau.

He hōʻuluʻulu manaʻo wale nō kēia. Inā he mau nīnau hou aku kāu e pili ana i kēia lāʻau lapaʻau, mai kānalua e nīnau i kāu kauka, kauka lāʻau, a i ʻole kekahi mea mālama ola kino ʻē aʻe. E hiki iā lākou ke kōkua iā ʻoe.

glucarpidase, methotrexate, maʻi puʻupaʻa, nā enzymes, nā pilina lāʻau, nā hopena ʻaoʻao, ka lāʻau pale