Ua lilo koke anei kou pōʻaiapuni menstrual i mea ʻē? A i ʻole ke manaʻo nei ʻoe i kahi pehu a kaumaha ma kou ʻōpū haʻahaʻa? I kekahi manawa manaʻo mākou he mau mea maʻamau kēia, akā i kēia lā ke kamaʻilio nei mākou e pili ana i kahi kumu e hopohopo iki paha. He ʻano kēia i kapa ʻia ʻo Granulosa Cell Tumor (GCT). Mai makaʻu i kou lohe ʻana i kēia inoa, he mea nui loa ia e makaʻala i kēia.
I ka ʻōlelo maʻalahi, he aha ka Granulosa Cell Tumor (GCT)?
ʻO ka Granulosa Cell Tumor (GCT) kahi ʻano puʻupuʻu e ulu ana i loko o nā ovaries o nā wahine. E like me kou ʻike, he ʻāpana koʻikoʻi loa nā ovaries o kā mākou ʻōnaehana hānau wahine. Ma waho aʻe o ka hana ʻana i nā hua manu, hana pū kēia mau ovaries i ʻelua mau hormones wahine i kapa ʻia ʻo estrogen a me progesterone.
ʻO ke ʻano kūikawā o kēia mau puʻupuʻu GCT, ʻo ia ka hana ʻana i ka nui o ka hormone estrogen . ʻO ia ke kumu e ʻike ʻia ai nā loli a me nā hōʻailona like ʻole i loko o ke kino. ʻOiai hiki i kēia mau puʻupuʻu ke ulu i kēlā me kēia makahiki, ʻike pinepine ʻia lākou ma kahi o 50 mau makahiki.
He maʻi laha ʻole ka GCT. He 5% wale nō ia o nā ʻōpū ovarian āpau. Akā, he mea nui e makaʻala iā ia no kou olakino.
He ʻino anei kēia mau puʻupuʻu?
ʻAe, ʻo ka Granulosa Cell Tumor kahi ʻano puʻupuʻu e hāʻule pinepine ana i loko o ka māhele malignant . Akā ʻo ka mea nui e pono ai ʻoe e hoʻomanaʻo ma ʻaneʻi, ʻo ka hapa nui o kēia mau puʻupuʻu e ulu lohi loa . Ma muli o kēia, ʻoi aku ka nui o nā manawa e ʻike ai iā lākou i nā pae mua. Inā ʻike mua ʻia lākou, maikaʻi loa nā hopena o ka mālama ʻana. No laila, ʻaʻohe pono e hopohopo.
Aia kekahi ʻokoʻa ma waena o nā GCT e ulu ana i ka poʻe ʻelemakule a me ka poʻe ʻōpio?
ʻAe, aia kahi ʻokoʻa iki. ʻIke pinepine ʻia kēia ʻano ma nā wahine ʻelemakule. 95% o nā maʻi i ʻike ʻia he mau wahine ʻelemakule i ulu maikaʻi.
Eia nō naʻe, inā ulu kēia puʻupuʻu i loko o kahi kanaka ʻōpio ma lalo o 30 mau makahiki, he ʻano paha ia i kapa ʻia ʻo Juvenile GCT . I kekahi manawa hiki i kēia ʻano Juvenile GCT ke ulu wikiwiki iki ma mua o ke ʻano e ulu ana i nā pākeke, a ʻoi aku paha ka nui o ka hiki ke hoʻi hou i kekahi mau makahiki ma hope o ka mālama ʻana.
He aha ke kumu o ka hoʻokumu ʻana o kahi GCT?
ʻAʻole maopopo loa i nā loea ke kumu o kēia, akā i ka hapanui o ka manawa, ua hoʻokumu ʻia kēia mau puʻupuʻu e kahi mutation i loko o kahi gene i kapa ʻia ʻo FOXL2., ʻo ia hoʻi, ʻike ʻia kekahi loli. ʻO ka hana nui o kēia gene ke kōkua i ka ulu olakino o nā cell granulosa. No laila, i ka wā e loli ai kēia gene, hiki i nā cell ke ulu ma ke ʻano ʻē a hana i nā tumors e like me kēia.
Loaʻa iā ʻoe kēia mau hōʻailona?
ʻO ka hōʻailona nui o ka GCT ka piʻi ʻana o nā pae estrogen i loko o ke kino. Hiki ke ʻokoʻa nā hōʻailona e loaʻa mai ana mai kēia ma muli o kou mau makahiki.
- Hiki i ke kaikamahine ke hōʻike i nā hōʻailona o ka ʻōpio i ka wā ʻōpiopio.
- I nā wāhine ʻelemakule , he mea maʻamau nā hōʻailona ma lalo nei.
| Hōʻailona | Wehewehena |
|---|---|
| Ke kahe koko ʻole | ʻO ke kahe koko hou ʻana i nā wahine i pau i kā lākou pōʻaiapuni menstrual (ma hope o ka menopause) a i ʻole ke kahe koko ʻana o ka ʻōpū maʻamau i nā wahine ʻōpio. |
| Pehu ʻōpū | Ka hoʻonui ʻana a i ʻole ka manaʻo o ka pehu ʻana ma ka ʻōpū lalo. |
| Nā loli i ke kaʻina hana menstrual | Ka pau ʻana o ka menstruation i ke ʻano kūpono ʻole a i ʻole ka pau piha ʻana. |
| ʻEha umauma | ʻEha a palupalu paha ka umauma. |
| ʻEha ʻōpū haʻahaʻa | ʻO ka maʻamau, hana wale kēia inā haki ka cyst, hiki iā ia ke hōʻeha koke a ʻeha nui. |
He aha nā pilikia e hiki mai ana inā ʻaʻole mālama ʻia?
Inā ʻaʻole mālama ʻia kēia kūlana i ka manawa kūpono, piʻi aʻe ka pilikia o nā pilikia olakino ʻē aʻe i ka wā e kiʻekiʻe ai ka nui o ka estrogen i loko o ke kino.
| Ka pilikia hiki ke loaʻa | I ka ʻōlelo maʻalahi... |
|---|---|
| ʻO ka Hyperplasia Endometrial | Ka mānoanoa ʻano ʻē o ka paia o loko o ka ʻōpū. |
| Ka maʻi ʻōpū | Hoʻonui ʻia ka pilikia o ka hoʻomohala ʻana i nā hunaola kanesa o ka ʻōpū. |
| Ka maʻi ʻaʻai umauma | Hiki ke hoʻonui iki ʻia ka pilikia o ka maʻi ʻaʻai umauma. |
| Ka hānau ʻole ʻana | Ka hopena i ka hiki ke loaʻa nā keiki. |
Pehea e ʻike ai nā kauka i kēia maʻi?
Ke haʻi aku ʻoe i kāu kauka e pili ana i nā hōʻailona i luna, e nānā ʻo ia iā ʻoe a kauoha i kekahi mau hoʻokolohua e hōʻoia i ke kūlana.
- Kiʻi: Hiki i kēia ke pili i kahi CT scan , MRI scan , a i ʻole, ʻo ka mea maʻamau , kahi ultrasound transvaginal , ʻo ia hoʻi kahi scan i hana ʻia ma o ka vagina.
- Nā Hoʻāʻo Koko: Nānā kēia mau hoʻāʻo no kekahi mau māka puʻupuʻu, e like me Inhibin, i hana ʻia e nā GCT. Nānā pū lākou no nā kūlana ʻē aʻe.
He aha nā koho lapaʻau?
ʻO ke ʻoki kino ka mea mua a me ka mea nui no GCT.Maanei, hoʻāʻo ke kauka lapaʻau e wehe i ka nui o ka puʻupuʻu me ka ʻole o ka hōʻino ʻana i nā ʻiʻo olakino.
Inā he ʻōpiopio ʻoe, ʻaʻole e hoʻolālā e loaʻa nā keiki, a i ʻole ua postmenopausal, hiki i kāu kauka ke ʻōlelo aku i kahi oophorectomy , ʻo ia hoʻi ka wehe ʻana i ka ovary holoʻokoʻa e loaʻa ana ka puʻupuʻu. I kekahi mau hihia, pono paha ka hysterectomy .
Ke hoʻoholo nei i ke kahua o ka maʻi ʻaʻai (staging)
Ma hope o ke ʻoki ʻana, ua hoʻoholo ʻia ke "kahua" e ʻike ai inā ua pālahalaha ke kanesa.
- Pae 1: Ua hoʻopaʻa ʻia ka puʻupuʻu i nā ovaries a ʻaʻole i pālahalaha.
- Nā Pae 2 a 4: Ua pālahalaha ke kanesa (metastasized) i nā ʻāpana ʻē aʻe o ke kino.
ʻO ka nūhou maikaʻi, ua ʻike ʻia he 9 o 10 mau maʻi GCT i ka pae 1 , i ka wā e kaupalena ʻia ai ke kanesa i nā ovaries. I ia mau hihia, ua lawa paha ke ʻoki kino wale nō.
Ma muli o ka nui o ka puʻupuʻu a me ka pilikia o ka hoʻi hou ʻana, hiki ke ʻōlelo ʻia kekahi mau lāʻau lapaʻau ʻē aʻe ma waho aʻe o ke ʻoki ʻana.
- Kemoterapia
- Hoʻōla lāʻau hormone
- Hoʻōla radiation
He aha ka mea e hana ʻia ma hope o ka lāʻau lapaʻau?
Ma hope o ka wehe ʻia ʻana o ka puʻupuʻu, pono ʻoe e noho ma lalo o ka nānā ʻana o ke kauka no ka manawa lōʻihi, no ka mea, hiki i kēia mau puʻupuʻu ke hoʻi hou mai i kekahi manawa ma hope o nā makahiki . No laila, e nānā kāu kauka iā ʻoe i nā manawa maʻamau e hōʻoia ʻaʻole i hoʻi mai ka puʻupuʻu.
- Nā hoʻokolohua Pelvic
- Nā hoʻāʻo koko no nā hōʻailona kanesa
- Hoʻohana ʻia nā mea e like me nā scan no kēia.
Hiki anei ke ho'ōla piha ʻia mai kēia maʻi?
ʻAe, ʻoiaʻiʻo nō. Hiki ke ho'ōla loa ʻia ka Granulosa Cell Tumor, ʻoiai inā ʻike mua ʻia a wehe ʻia ma ke ʻoki ʻana.
Inā ʻike ʻia ke kanesa ma hope o kona laha ʻana i nā ʻāpana ʻē aʻe o ke kino, hiki ke hoʻemi ʻia ka manawa e ho'ōla ʻia ai. ʻO ia ke kumu e paipai aku ai mākou inā loaʻa iā ʻoe nā hōʻailona o kahi GCT, e ʻike koke i ke kauka .
Leka Lawe-Home
- ʻO ka Granulosa Cell Tumor (GCT) kahi puʻupuʻu kanesa laha ʻole, e ulu lohi pinepine ana i loko o nā ovaries.
- ʻO kēia ke kumu o ka hana nui ʻana o ka hormone estrogen, kahi e hoʻoulu ai i nā hōʻailona e like me ke kahe koko kūpono ʻole a me ka pehu ʻana.
- Inā he kanaka i pau kona pōʻaiapuni menstrual e kahe hou ana ke koko, a i ʻole he mau hōʻailona ʻē aʻe ʻē aʻe, mai hoʻokaʻulua. E ʻike koke i ke kauka.
- Inā ʻike ʻia i nā wā mua, hiki ke ho'ōla loa ʻia me ke ʻoki kino.
- He mea nui loa ka nānā ʻana i ke olakino no ka manawa lōʻihi, no ka mea, hiki i kēia mau puʻupuʻu ke hana hou ma hope o ka mālama ʻia ʻana.
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