Ke luhi mau nei ʻoe? He pilikia paha kēia me kou kelepa pituitary? (Hypopituitarism)

Ke manaʻo nei ʻoe i kekahi manawa ua nāwaliwali kou kino, me he mea lā ua nalowale kekahi mea? Malia paha ke kumu o kēia he pilikia liʻiliʻi ma kekahi o nā kelepa liʻiliʻi loa, akā he mea nui loa i loko o kou kino. I kēia lā e kamaʻilio mākou e pili ana i ka hypopituitarism , kahi maʻi kakaikahi e kū mai ana i loko o ka kelepa pituitary . Mai hopohopo, e kamaʻilio maʻalahi mākou e pili ana i kēia, ma ke ʻano hiki iā ʻoe ke hoʻomaopopo.

He aha ka hypopituitarism?

I ka ʻōlelo maʻalahi, ʻo ka hypopituitarism ka wā ʻaʻole lawa ka hana ʻana o kāu kelepa pituitary i nā hormones. I kēia manawa ke noʻonoʻo nei paha ʻoe i ke ʻano o kēia mau hormones. Ua like nā hormones me nā ʻelele kemika e lawe ana i nā leka e hana pono ai ko mākou kino. Hoʻomalu nā hormones pituitary i nā mea he nui, me kā mākou metabolism , ka ulu ʻana o ke kino, ka ulu ʻana o ka moekolohe, a me ka hānau hou ʻana.

E noʻonoʻo e like me ke kikowaena kauoha liʻiliʻi i loko o ko kākou kino, ʻo ia ka pituitary gland. Akā, ʻaʻole ia e hana hoʻokahi. Kōkua ʻia e kekahi ʻāpana koʻikoʻi o ka lolo i kapa ʻia ʻo hypothalamus . Ke haʻi aku nei ka hypothalamus i ka pituitary gland, "ʻAe, e hoʻokuʻu i ka hormone i kēia manawa." Hoʻomalu pū ka hypothalamus i nā mea e like me ke koko, ka helu o ka puʻuwai, ka mahana o ke kino, a me ka ʻai ʻana. No laila, inā he pōʻino a maʻi paha i ka pituitary gland a i ʻole ka hypothalamus, hiki iā ʻoe ke hoʻomohala i ka hypopituitarism.

Hiki ke hiki koke mai kēia ʻano, ʻoiai ma hope o kahi ulia. A i ʻole hiki ke ulu mālie i nā mahina a i ʻole nā ​​makahiki. I ka manawa pinepine, pono kēia poʻe e lawe i ka lāʻau lapaʻau no ke koena o ko lākou ola e kāohi i kā lākou mau hōʻailona. Akā, mai hopohopo, e nānā pono kāu kauka iā ʻoe a hāʻawi i ka lāʻau lapaʻau e pono ai.

Aia kekahi mau ʻano like ʻole o ka hypopituitarism?

ʻAe, hiki ke hoʻokaʻawale ʻia i ʻelua ʻano nui. Hoʻokumu ʻia kekahi ma ka nui o ka hormone i nele .

• Ka hemahema pituitary i hoʻokaʻawale ʻia: Ma kēia, hoʻokahi wale nō hormone pituitary i nele.
• Ka hemahema o ka hormone pituitary he nui: ʻO kēia ka wā e nele ai ʻelua a ʻoi aku paha nā hormones pituitary.
• Panhypopituitarism: He ʻano maʻi ʻole kēia kahi e hoʻemi ʻia ai nā hormones āpau i hana ʻia e ka pituitary gland.

A laila, ua hoʻokaʻawale ʻia lākou e like me ke kumu a pehea e hoʻopilikia ʻia ai ka pituitary gland :

• Hypopituitarism mua: Hana ʻia kēia e ka pōʻino a i ʻole ka maʻi e pili pono ana i ka pituitary gland.
• Hypopituitarism lua: Hana ʻia kēia e ka hōʻino a i ʻole ka maʻi i ka hypothalamus. E hoʻomanaʻo, ʻo ka hypothalamus ka mea e hāʻawi i nā kuhikuhi i ka pituitary gland.
• ʻO ka hypopituitarism idiopathic: I kekahi manawa ʻaʻole hiki ke loaʻa ke kumu.

He aha nā hōʻailona o ka Hypopituitarism?

ʻOkoʻa nā hōʻailona ma muli o ka hormone i nele . He kuleana ko kēia mau mea:

• Kou kāne/wahine .
• Kou mau makahiki i ka wā i hoʻomaka ai kēia maʻi .
• ʻO ke kumu o ka hypopituitarism.
• Pehea ka wikiwiki o ka emi ʻana o nā hormones .

I kēia manawa, e nānā kākou i nā hōʻailona e ʻike ʻia ke haʻahaʻa kēlā me kēia hormone.

Nā Hōʻailona o ka hemahema o ka Hormone ulu (GH)

No nā pēpē hānau hou:

• Haʻahaʻa ke kō koko (Hypoglycemia) .
• Ka loaʻa ʻana o kahi penis kāne liʻiliʻi ʻē aʻe (Micropenis) .

No nā keiki ʻōpio:

• Lohi loa ka ulu ʻana a ʻaʻole loa paha. Eia kekahi laʻana, inā ʻaʻole like ke kiʻekiʻe o kāu keiki me nā keiki ʻē aʻe o ko lākou mau makahiki, he hōʻailona paha kēia o kēia.
• Kiʻekiʻe pōkole .
• Ka lohi a i ʻole ka hala ʻole o ka ulu ʻana o ka moekolohe i ka wā ʻōpio.

No nā mākua:

• Luhi nui mau . Manaʻo e like me ka make ʻana o ka pila.
• ʻAʻole hauʻoli a māʻona hoʻi i ke ola.
• Ua emi ka hana moekolohe a me ka makemake .
• Ka hoʻonui ʻia o ka waiho ʻana o ka momona, ʻoi aku hoʻi a puni ka pūhaka .
• Ka emi ʻana o ke ahonui i ke anu a me ka wela .
• Ua emi ka nui o nā ʻiʻo .
• Ua emi ka ikaika a me ke ahonui i ka wā e hoʻoikaika kino ai.

Nā hōʻailona o ka hemahema o ka Thyroid-Stimulating Hormone (TSH)

No nā pēpē hānau hou:

• Ua emi ke kani o nā ʻiʻo (manaʻo nā lālā ʻaʻohe ola).
• Haʻahaʻa o ke kino (Hypothermia) .
• Manaʻo pehu .
• E uē ana me ka leo ʻoʻoleʻa a pahee .

No nā keiki ʻōpio a me nā mākua:

Ua like nā hōʻailona o kēia me nā hōʻailona o ka hypothyroidism , no ka mea, hoʻoulu ka hormone TSH i ka ʻōpū thyroid e hana i kāna mau hormones ponoʻī.

• Luhi loa .
• ʻIli maloʻo a me ka lahilahi/haʻule o ka lauoho .
• Ka paʻa ʻana o ka ʻōpū .
• Ka piʻi ʻana o ke kaumaha .
• Ka nāwaliwali o nā ʻiʻo .
• Ka emi ʻana o ka hiki ke hoʻomanawanui i ke anu .
• Nā kūlana noʻonoʻo e like me ke kaumaha .
• Hiki i nā wāhine ke loaʻa i ka menstruation kūpono ʻole a i ʻole ke kahe koko nui ma mua o ka maʻamau .

Nā hōʻailona o ka Follicle-Stimulating Hormone (FSH) a me/a i ʻole Luteinizing Hormone (LH) hemahema

He mau hormones ʻo FSH a me LH i kapa ʻia he gonadotropins . Hoʻopilikia pololei kēia i kā mākou ʻōnaehana hānau keiki .

No nā keiki hānau hou:

• Ka loaʻa ʻana o kahi penis kāne liʻiliʻi ʻē aʻe (Micropenis) .
• Nā testicles i iho ʻole i lalo .

No nā keiki ʻōpio:

• ʻAʻole i ulu ka umauma i nā kaikamahine.
• ʻAʻole e hoʻonui ʻia nā testicles o nā keikikāne .
• ʻAʻole ʻike ke kino i ka piʻi koke ʻana o ke kiʻekiʻe (growth spurt) i ka wā ʻōpio.

No nā kāne:

• Ua emi ka makemake moekolohe .
• Luhi loa .
• Ka hānau ʻole ʻana .
• Ka hana ʻino o ka erectile .
• Ka nalowale ʻana o ka lauoho maka a i ʻole ke kino .

No nā wāhine:

• Haʻahaʻa ka libido .
• Luhi loa .
• Ka hānau ʻole ʻana .
• Wela wela - He manaʻo koke o ka wela i loko o ke kino.
• Ka menstruation kūpono ʻole a i ʻole ka pau ʻana o ka menstruation (Amenorrhea) .
• Ka nalowale ʻana o ka lauoho ma ka ʻōpū lalo .
• ʻO ka hiki ʻole ke hana i ka waiū umauma ma hope o ka hānau ʻana o ke keiki .

Nā Hōʻailona o ka Adrenocorticotropic Hormone (ACTH a i ʻole Corticotropin) Deficiency

No nā pēpē hānau hou:

• Haʻahaʻa ke kō koko (Hypoglycemia) .
• Lohi loa ka piʻi ʻana o ke kaumaha (ʻAʻole ulu pono) . Me he mea lā ʻaʻole e ʻū ana ke pēpē ʻoiai ua lawa kāna waiū e inu ana.
• Nā ʻūlū .
• Melemele o ka ʻili (Jaundice) .

No nā keiki ʻōpio a me nā mākua:

• Luhi loa .
• ʻO ka pohō kaumaha me ke kumu ʻole .
• Ke koko haʻahaʻa (Hypotension) .
• Ka luaʻi a me ka luaʻi .
• Haʻahaʻa ke kō koko (Hypoglycemia) .
• Ka huikau, ka nalowale o ka ʻike .

Nā hōʻailona o ka nele o Prolactin

ʻO ke ʻano nui o kēia ka nele o ka waiū umauma ma hope o ka hānau ʻana o kahi pēpē .

Nā Hōʻailona o ka hemahema o ka Oxytocin

• Nā pilikia hānai waiū ma hope o ka hānau ʻana o ke pēpē.
• Ke pilikia o ka hoʻomaka ʻana me ke keiki ma hope o ka hānau ʻana.
• ʻAʻohe lokomaikaʻi no ke kaumaha o haʻi.
• Ka paʻakikī e launa pū me nā poʻe ʻē aʻe.

Nā Hōʻailona o ka Hormone Antidiuretic (ADH a i ʻole Vasopressin a i ʻole Arginine Vasopressin) Deficiency

No nā pēpē hānau hou:

• Luaʻi .
• Nā kuni o ke kumu i ʻike ʻole ʻia .
• Uē nui loa .
• Ka emi ʻana o ke kaumaha .
• Ka paʻa ʻana o ka ʻōpū .
• Ka pulu pinepine ʻana o ka diaper (Nā diaper pulu loa) .

No nā keiki ʻōpio:

• Ka paʻakikī i ke aʻo ʻana i ka lua .
• Ka pulu ʻana i ka moena .
• Ka luhi koke ʻana .

No nā mākua:

• Ka mimi pinepine ʻana .
• Ka makewai nui .
• Nā kaulike ʻole o ke electrolyte .

Mea nui: Mai hopohopo inā loaʻa iā ʻoe kekahi a ʻelua paha o kēia mau hōʻailona, ​​​​akā inā hoʻomau lākou, ʻoi aku ka maikaʻi o ka ʻimi ʻana i ke aʻo lapaʻau.

He aha nā kumu o ka hypopituitarism?

Nui nā kumu no kēia ʻano. I kekahi manawa, ʻaʻole hiki i nā kauka ke kuhikuhi i ke kumu pololei. Ma keʻano laulā, hiki ke hana ʻia e ʻekolu mau mea nui:

1. Ke kaomi ʻana i ka pituitary gland a i ʻole hypothalamus.

2. Ka hōʻino ʻana i ka pituitary gland a i ʻole hypothalamus.

3. Loaʻa i kahi maʻi lapaʻau laha ʻole a i ʻole kekahi maʻi ʻē aʻe e hoʻoulu ai i ka hypopituitarism.

Nā kūlana e pili ana i ka pituitary gland a i ʻole hypothalamus

ʻO nā kūlana e hiki ke kau i ke kaomi ma kēia mau ʻāpana o ka lolo a hoʻoulu i ka hypopituitarism:

• ʻO nā adenomas pituitary: He mau puʻupuʻu maikaʻi ʻole kēia e hana ʻia ana i loko o ka pituitary gland. Hiki iā lākou ke hoʻololi i ke ʻano o ka hana ʻana o nā hormones.
• Nā puʻupuʻu lolo: Hiki i nā puʻupuʻu e ulu kokoke ana i ka hypothalamus a i ʻole ka pituitary gland ke hoʻopilikia i ka hana ʻana o ka hormone.
• ʻO ka lymphocytic hypophysitis (LH): He kūlana kakaikahi kēia. Maanei, hoʻouka nā pūnaewele i kapa ʻia ʻo lymphocytes i ka pituitary gland. (ʻAʻole pono e huikau kēia LH me ka Luteinizing Hormone i ʻōlelo ʻia ma mua, ʻeā?!)
• ʻO ka sarcoidosis pituitary a i ʻole hypothalamus: ʻO ka Sarcoidosis kahi maʻi e hoʻoulu ai i ka mumū.

Nā hanana e hōʻino ai i ka pituitary gland a i ʻole hypothalamus

• ʻOki: Nā pilikia i ka wā o ke ʻoki ʻana i ka lolo (ʻoi aku ka ʻoki ʻana e wehe i nā adenomas pituitary).
• Lapaʻau radiation: Hoʻohana ʻia ka radiation e mālama i nā lāʻau lapaʻau maʻi kanesa ma mua a i ʻole nā ​​adenomas pituitary.
• Nā ʻeha poʻo koʻikoʻi (ʻeha lolo traumatic - TBI):Nā mea e like me nā ulia kaʻa, hāʻule, a me nā ʻeha haʻuki.
• Pituitary apoplexy: Ka luku koke ʻia ʻana o nā ʻiʻo pituitary gland.

Nā kūlana olakino kakaikahi

• ʻO ka hemochromatosis hoʻoilina: He kūlana hoʻoilina kēia. Hoʻoulu ia i ka hao keu e hōʻiliʻili i loko o ke koko. Hiki i kēia ke hōʻino i ka pituitary gland.
• ʻO ka maningitis bacteria: ʻOiai he mea kakaikahi, hiki ke hana ʻia ka hypopituitarism ma ke ʻano he pilikia o ka maningitis bacteria.
• Nā hoʻololi hoʻoilina: Hiki i kekahi mau kūlana hoʻoilina kakaikahi ke hana i nā hemahema o ka hormone pituitary.

He aha nā kumu pilikia?

ʻO nā kūlana a i ʻole nā ​​​​hanana e hiki mai ana he mau mea pilikia no ka hypopituitarism:

• Ma hope o ka loaʻa ʻana o nā lāʻau lapaʻau maʻi kanesa a me ka radiation ma mua.
• ʻEha poʻo a lolo paha: Ma waena o 27% a me 32% o ka poʻe i loaʻa i kahi ʻeha poʻo traumatic (TBI) e hoʻomohala i ka hypopituitarism.
• ʻAʻai anemia cell sickle: Hiki i kēia maʻi ke hana i nā hemahema o ka hormone pituitary.
• ʻO ka maʻi diabetes ʻano 1: ʻO ka hōʻino ʻana i nā aʻalolo a me nā kīʻaha koko i hoʻokumu ʻia e ka maʻi diabetes ʻano 1 i kāohi ʻole ʻia e hiki ke kōkua i kēia maʻi.
• Hāpai a me ka hānau keiki ʻana: ʻO ke kahe nui ʻana o ke koko ma hope o ka hānau keiki ʻana hiki ke hōʻino i ka pituitary gland. Ua kapa ʻia kēia ʻano maʻi ʻo Sheehan syndrome .

Nā pilikia hiki ke loaʻa

ʻO nā hemahema o ka hormone e hele pū me ka hypopituitarism hiki ke alakaʻi i ka ulu ʻana o nā kūlana ʻē aʻe. ʻOkoʻa kēia mau hopena ma muli o ka hormone i nele. Eia kekahi mau laʻana:

• Hiki i ka hemahema o ka GH (hormone ulu) ke kumu i ka momona , ka cholesterol kiʻekiʻe , a me ka metabolic syndrome .
• ʻO ka nele o nā hormones estrogen (ma muli o ka nele o FSH) hiki ke hana i ka osteoporosis ( lahilahi o nā iwi) i nā wahine.
• Hiki i ka hemahema o ka ACTH ke hoʻoulu i kahi pilikia adrenal , kahi pilikia e hoʻoweliweli ana i ke ola.

He aha nā hoʻokolohua e hana ʻia e ʻike ai i kēia maʻi?

Hiki i kāu kauka ke kauoha i kekahi o kēia mau hoʻokolohua e ʻike i ka hypopituitarism:

• Nā hoʻāʻo koko no nā pae hormone: Ma muli o kāu mau hōʻailona, ​​​​hiki i kāu kauka ke kauoha i nā hoʻāʻo koko e ana i nā pae hormone like ʻole.
• Nā hoʻāʻo hoʻoulu ʻana i ka hormone: Ma kēia hoʻāʻo, e hāʻawi kāu kauka iā ʻoe i kahi lāʻau lapaʻau e hoʻoulu i kāu pituitary gland e hoʻokuʻu i ka hormone e hoʻāʻo ʻia nei. A laila, lawe ʻia kahi hāpana koko a hoʻouna ʻia i kahi lab no ka hoʻāʻo ʻana.
• Hoʻāʻo hoʻomanawanui insulin: Hiki i kēia ke ʻike i nā hemahema o ka hormone ulu (GH) a me ACTH.
• Nā hoʻāʻo Osmolality no ke koko a me ka mimi: Hoʻāʻo kēia no ka hemahema o ka hormone antidiuretic (ADH).
• MRI (Magnetic Resonance Imaging) Scan: Lawe nā scan MRI i nā kiʻi kikoʻī o loko o kou kino. Ua manaʻo ʻia nā scan MRI o ka lolo ʻo ke ala maikaʻi loa e ʻike ai i nā puʻupuʻu pituitary e hoʻoulu ai i ka hypopituitarism.
• ʻO ke scan CT (Computed Tomography) o ka lolo: Hiki ke hoʻohana ʻia kēia hoʻāʻo e ʻike inā he puʻupuʻu lolo a i ʻole ka adenoma pituitary e hoʻokumu nei i kēia kūlana.

Pehea e mālama ʻia ai ka hypopituitarism?

ʻOiai ʻaʻohe lāʻau lapaʻau, hiki ke mālama ʻia . Aia ka lāʻau lapaʻau i nā hormones i nele a me ke kumu o kou kūlana . E kōkua kāu hui lapaʻau iā ʻoe e hoʻomohala i kahi hoʻolālā lapaʻau i kūpono loa iā ʻoe. ʻO nā koho lapaʻau maʻamau:

• Lapaʻau hoʻololi hormone: ʻO ka pahuhopu o kēia, ʻo ia ke hoʻihoʻi i nā hormones pituitary i emi i nā pae maʻamau. I ka hapanui o nā hihia, pono e lawe ʻia ka lāʻau lapaʻau no ke koena o kou ola.
• ʻO ke ʻoki kino: Pono paha nā poʻe me nā adenomas pituitary i ke ʻoki kino e wehe iā lākou.
• Lapaʻau radiation: Hiki i ka lāʻau radiation ke kōkua i ka hoʻemi ʻana i nā adenomas pituitary.

Hiki i kāu kauka ke ʻōlelo aku iā ʻoe e lawe mau i kahi kāleka ID lapaʻau a kūpeʻe lima paha me ʻoe, inā he pilikia.

He aha ka wānana no ka hypopituitarism?

He ʻokoʻa ke ʻano o ka nānā ʻana, ma muli o kēia mau kumu:

• Kou makahiki i hoʻomaka ai kāu mau hōʻailona .
• Ke kumu o kou kūlana .
• Pehea ka haʻahaʻa o ka hopena o nā hormones .
• Pehea e pane ai kou kino i ka lāʻau lapaʻau .

He nui ka poʻe me ka hypopituitarism e ola olakino ana. Eia nō naʻe, inā he pōʻino pituitary lōʻihi, ʻoi aku ka pōkole o ke ola ma mua o ka mea o ka makahiki like ʻole i loaʻa ʻole ke ʻano. Eia nō naʻe, ʻaʻole i hoʻemi ʻia ke ola no ka poʻe e hahai ana i kahi hoʻolālā lapaʻau kūpono .

He aha inā he pilikia? Inā ulu koke ka hypopituitarism, he koʻikoʻi, a waiho ʻole ʻia me ka mālama ʻole ʻia, hiki ke lilo i pilikia olakino a hiki i ka make. No laila, inā ʻike ʻoe i nā hōʻailona, ​​e ʻike koke i ke kauka.

Āhea wau e ʻike ai i ke kauka?

I ka hapanui o nā hihia, pono ka nānā pono ʻana i nā hormones i hoʻopilikia ʻia no ke ola holoʻokoʻa no ka hypopituitarism. E ʻike pinepine i kāu kauka e hōʻoia i ka hana pono ʻana o kāu hoʻolālā lapaʻau.Inā loaʻa iā ʻoe nā hōʻailona hou a hopohopo paha, e kelepona koke aku i kāu kauka.

He aha nā nīnau e pono iaʻu e nīnau aku i kaʻu kauka?

Inā ua ʻike ʻia ʻoe me ka hypopituitarism, makemake paha ʻoe e nīnau i kāu kauka i kēia mau nīnau:

• He aha ke ʻano o ka hypopituitarism i loaʻa iaʻu?
• He aha nā hormones i haʻahaʻa i loko oʻu?
• He aha ke kumu o kēia?
• He aha nā koho lapaʻau e loaʻa iaʻu?
• Aia kekahi mau hopena ʻaoʻao mai kaʻu lāʻau lapaʻau?
• ʻEhia ka lōʻihi e pono ai iaʻu e lawe i ka lāʻau lapaʻau?
• E pili anei kēia i koʻu hānau keiki?
• E hoʻopilikia anei kēia i koʻu hāpai ʻana?
• Hiki paha kēia i kaʻu mau keiki pū kekahi?

ʻO ka mea hope loa, e hoʻomanaʻo (Leka Lawe-Home)

Hiki ke hopohopo kahi hōʻailona hou, akā mai makaʻu e nīnau i kāu kauka e pili ana i ka hypopituitarism. I nā hihia he nui, pono ka mālama ʻana i ke ola holoʻokoʻa a me ka nānā ʻana i ka hormone. ʻO ia ke kumu he mea nui e ʻike pinepine i kāu kauka. Inā loaʻa iā ʻoe kekahi mau hōʻailona hou a hopohopo paha, e kelepona i kāu kauka. Aia lākou ma laila e kōkua iā ʻoe. Me ka hoʻokele kūpono, hiki iā ʻoe ke ola i kahi ola olakino a ikaika.

` hypopituitarism, pituitary gland, hormones, nele i ka hormone, hypothalamus, hormone ulu, thyroid, adrenal, Sri Lanka Health, Pituitary gland, nele i ka hormone