ʻO ke Kanesa ʻUma Luminal A: Mai makaʻu akā e makaʻala!

Ke lohe kākou i ka huaʻōlelo kanesa umauma, makaʻu iki kākou a pau. Akā, ua ʻike anei ʻoe, ʻaʻole like nā kanesa umauma a pau? Aia kekahi mau ʻano, inā ʻike mua ʻia a mālama pono ʻia, ʻoi aku ka nui o ka hiki ke ho'ōla ʻia. No laila, ʻo kekahi ʻano kanesa umauma a kākou e kamaʻilio nei i kēia lā ua kapa ʻia ʻo 'Luminal A'. No laila, e kamaʻilio hou aku kākou e pili ana i kēia?

He aha ke ʻano o ka maʻi ʻaʻai umauma Luminal A?

I ka ʻōlelo maʻalahi, he ʻano maʻi ʻaʻai umauma kēia e hilinaʻi ana i ka hormone (Hormone Receptor-Positive a i ʻole HR+) . I kēia manawa ke noʻonoʻo nei ʻoe, "He aha kēia mea hormone?" Loaʻa iā mākou ʻelua mau hormones i loko o ko mākou kino i kapa ʻia ʻo estrogen a me progesterone. I loko o kēia mau cell cancer, aia nā protein kūikawā e hiki ke hoʻopaʻa i kēia mau hormones, e like me ka laka e kūpono i kahi kī. Kāhea mākou i kēia mau receptors . No laila, ke hele mai kēia mau hormones a hoʻopaʻa i kēlā mau receptors, kōkua lākou i ka ulu ʻana o nā cell cancer. ʻO ka huaʻōlelo 'luminal' e pili ana i ka papa o nā cell i loko o nā ducts waiū o ka umauma. ʻO kēia kahi e hoʻomaka ai ka hapa nui o nā maʻi ʻaʻai umauma.

He nui nā ʻano kūikawā o nā hunaola kanesa Luminal A:

• ʻO ka Estrogen Receptor-Positive (ER+): ʻO ia hoʻi, he kiʻekiʻe ka pae o nā mea loaʻa estrogen (ERs) i loko o kēia mau cell, hiki ke hoʻopaʻa i ka hormone estrogen. ʻO ia hoʻi, hiki i nā cell kanesa ke ulu mai ka hormone estrogen.
• ʻO ka Progesterone Receptor-Positive (PR+): Loaʻa i kēia mau cell nā mea loaʻa hou aku (PR) e hoʻopaʻa ana i ka hormone progesterone. Kōkua pū kēia i ka ulu ʻana o nā cell cancer.
• HER2-Negative a i ʻole HER2-: He ʻoi aku ka hohonu o kēia. ʻO HER2 (Human Epidermal Growth Factor Receptor 2) kekahi protein kūikawā. Hiki ke loaʻa i nā nui he nui ma ka ʻili o kekahi mau cell cancer, hiki ke kōkua i ka laha koke ʻana o ke kanesa. Eia nō naʻe, ʻaʻohe protein HER2 o nā cell Luminal A. He mea maikaʻi kēlā. (Hiki i nā ʻano maʻi umauma ʻē aʻe, e like me Luminal B, ke HER2-maikaʻi a maikaʻi ʻole paha.)
• ʻO ka protein Ki-67 haʻahaʻa: ʻO Ki-67 kahi protein i loaʻa wale i nā cell e māhele wikiwiki ana. He haʻahaʻa loa nā pae o kēia protein i nā maʻi kanesa Luminal A. ʻO ke ʻano kēia, e māhele mālie ana kēia mau cell kanesa, ʻo ia hoʻi ka ulu lohi ʻana o ke kanesa. ʻO kēia ka ʻokoʻa nui ma waena o kēia ʻano kanesa a me nā ʻano ʻē aʻe e like me Luminal B.
• Papa Haʻahaʻa: I ka ʻōlelo maʻalahi, ʻaʻole like ka ikaika o nā pūnaewele Luminal A me nā ʻano maʻi ʻē aʻe. ʻAʻole hoʻi lākou e hoʻi hou ma hope o ka mālama ʻana ma mua o nā pūnaewele Luminal B.

Me he mea lā he mea paʻakikī iki kēia ʻike iā ʻoe. Ke noʻonoʻo nei paha ʻoe, "He aha nā ER, PR, HER2, Ki-67?" Akā, he mea nui loa kēia mau mea.ʻO kēia nā mea e hāʻawi i ka ʻike pae molekala e pili ana i nā hunaola kanesa i loko o kou umauma. Ma muli o kēia ʻike, hiki i kāu kauka ke hana i kahi hoʻolālā lapaʻau pilikino e kūpono iā ʻoe a wānana pehea ʻoe e pane ai i nā lāʻau like ʻole.

Pehea ka maʻamau o ke kanesa umauma Luminal A?

ʻO ka ʻoiaʻiʻo, ʻo kēia ke ʻano maʻamau o ka maʻi ʻaʻai umauma. Ua hōʻike ʻia aia ma waena o 50% a me 60% o nā maʻi maʻi umauma āpau i loaʻa i kēia ʻano, i kapa ʻia ʻo Luminal A. ʻO ia hoʻi, i ka wā e kamaʻilio ai e pili ana i ka maʻi ʻaʻai umauma, he mea nui loa ka ʻike e pili ana i kēia ʻano.

He aha nā hōʻailona o ke kanesa o ka umauma Luminal A?

I kekahi manawa hiki ke ulu kēia maʻi kanesa me ka ʻole o nā hōʻailona. ʻO ia ke kumu e paipai mau ai nā kauka i nā hoʻokolohua umauma maʻamau (Routine Cancer Screenings). Inā ʻike mua ʻia, ʻoi aku ka maʻalahi o ka mālama ʻana. Eia nō naʻe, hiki i kekahi poʻe ke ʻike i nā hōʻailona e like me kēia:

• He puʻupuʻu a cyst paha i loko o ka umauma: ʻO kēia ka hōʻailona maʻamau. Hiki ke manaʻo ʻia e like me kahi puʻupuʻu i hiki ke paʻi ʻia a ʻaʻole ma laila ma mua.
• ʻEha umauma: Hiki i kekahi poʻe ke ʻeha ma ka umauma a i ʻole ka ʻāpana armpit.
• Hoʻokahe wai mai ka nipple: I kekahi manawa, ʻo kahi kahe wai ʻaʻole waiū akā e like me ke koko e puka mai ana mai ka nipple.
• Ka mānoanoa a i ʻole ka dimpling o ka ʻili o ka umauma: Nā loli i ka ʻili o ka umauma, e like me ke ʻano o ka dimpled ma kekahi mau wahi, a i ʻole ke ʻano e like me ka ʻili ʻalani.
• Pehu ʻana o ka umauma a i ʻole ka ʻūlū: Hiki ke ʻike ʻia kekahi umauma i ʻoi aku ka nui ma mua o kekahi, a i ʻole he hōʻailona paha ka ʻāpana ʻūlū.

E hoʻomanaʻo, ʻo ka loaʻa ʻana o kēia mau hōʻailona ʻaʻole ia he manaʻo he maʻi ʻaʻai umauma kou. Eia nō naʻe, inā ʻike ʻoe i kekahi o kēia mau hōʻailona, ​​​​he mea naʻauao mau ke ʻike i ke kauka no ka nānā ʻana.

He aha ke kumu o ka maʻi ʻaʻai umauma Luminal A?

ʻO ka ʻoiaʻiʻo, loaʻa ka maʻi ʻaʻai umauma i ka wā e loli koke ai nā hunaola umauma olakino a hoʻomaka e ulu me ka ʻole o ke kāohi ʻia. ʻAʻole maopopo i nā loea ke kumu o kēia. Eia nō naʻe, ua ʻike lākou i kekahi mau mea pilikia e hoʻonui ai i ka pilikia o ka loaʻa ʻana o ka maʻi ʻaʻai umauma. ʻO lākou:

• Moʻolelo ʻohana o ka maʻi ʻaʻai umauma a i ʻole ka maʻi ovarian: Inā ua loaʻa i kou makuahine, kaikuahine, a kaikamahine paha ka maʻi ʻaʻai umauma, aia ʻoe i kahi pilikia kiʻekiʻe iki aʻe.
• ʻOi aku ma mua o 50 mau makahiki: Piʻi kēia pilikia me ka makahiki.
• Loaʻa nā ʻiʻo umauma mānoanoa: ʻO ka poʻe me nā ʻiʻo umauma mānoanoa ma ka mammogram ʻoi aku ka nui o ka pilikia.
• Ka hoʻohana ʻana i ka waiʻona: ʻOi aku ka nui o ka pilikia o ka poʻe inu waiʻona pinepine.
• Ma hope o ka loaʻa mua ʻana o ka lāʻau lapaʻau radiation ma ka ʻāpana umauma:Inā ua loaʻa iā ʻoe ka lāʻau lapaʻau radiation ma ka umauma no kekahi maʻi ʻē aʻe.
• ʻO ka lōʻihi o ka launa ʻana me nā hormones e like me ka estrogen a i ʻole ka progesterone: Aia kekahi mau kumu no kēia. No ka laʻana, ka menarche mua (ka menstruation mua) , ka menopause hope (ka menopause hope) , a i ʻole ka lawe ʻana i kekahi mau lāʻau hoʻololi hormone (HRT) no ka manawa lōʻihi.

ʻAʻole nā ​​kānaka a pau i loaʻa i kēia mau kumu pilikia e loaʻa i ka maʻi kanesa. Eia kekahi, hiki i kekahi mea i loaʻa ʻole i kekahi o kēia mau kumu ke loaʻa iā ia. No laila he mea nui ka nānā mau ʻana .

Pehea e ʻike ʻia ai ke kanesa o ka umauma Luminal A?

ʻIke mua ʻia ke kanesa o ka umauma ma o nā mammograms nānā . Inā hōʻike kāu mammogram i kekahi mea kānalua, e kauoha kāu kauka i nā hoʻokolohua hou aʻe. Hiki i kēia mau mea ke komo pū me:

• ʻO ka Mammogram Diagnostic: He mammogram e nānā pono ana i ka wahi kānalua.
• Hoʻāʻo MRI (Magnetic Resonance Imaging): Hiki i kēia ke hana i nā kiʻi maopopo loa o ka umauma.
• Hoʻāʻo Ultrasound: Hiki i kēia ke kōkua i ka ʻike maikaʻi ʻana i nā mea e like me nā puʻupuʻu.

Ma hope o kēia mau hoʻokolohua, pono paha ʻoe e hana i kahi biopsy umauma . Pili kēia i ka lawe ʻana i kahi ʻāpana liʻiliʻi o ka ʻiʻo mai kahi wahi kānalua o ka umauma, hoʻouna iā ia i kahi keʻena hoʻokolohua a nānā iā ia ma lalo o kahi microscope. Hiki i kēia hoʻokolohua ke haʻi maopopo inā loaʻa nā hunaola kanesa a ʻaʻole paha.

Inā loaʻa i ke kauka maʻi nā hunaola kanesa, e hana ʻo ia i kekahi mau hoʻokolohua hou aʻe e hōʻoia inā no ke ʻano Luminal A kēia mau hunaola. ʻO ia hoʻi, e nānā lākou i nā mea e like me ER, PR, HER2, a me Ki-67 i ʻōlelo ʻia ma mua.

ʻO ka ʻike pono ʻana i ke ʻano o ka maʻi kanesa āu e loaʻa ai hiki ke kōkua i kāu kauka oncology e hoʻoholo i nā lāʻau lapaʻau e kūpono loa . Hiki iā ia ke hāʻawi iā ʻoe i kahi manaʻo o nā manawa kūpono e hoʻi hou mai ai ke kanesa ma hope o ka mālama ʻana.

Pehea e hoʻohana ʻia ai ʻo Luminal A no ka mālama ʻana i ka maʻi ʻaʻai umauma?

He maʻalahi ka maʻi ʻaʻai umauma Luminal A i ka hormone (HR+), no laila pane maikaʻi loa ia i ka lāʻau pale hormone . ʻO kēia kekahi o nā pono nui o kēia ʻano maʻi ʻaʻai. Aia kekahi mau koho lapaʻau:

• ʻO ka lāʻau pale hormone: Pili kēia i ka hāʻawi ʻana i nā lāʻau lapaʻau e ālai i ka hana o nā hormones (estrogen, progesterone) e kōkua ana i ka ulu ʻana o nā hunaola kanesa. Hoʻohana pinepine ʻia nā lāʻau lapaʻau e like me Tamoxifen a me Aromatase Inhibitors no kēia. I kekahi manawaHiki nō hoʻi ke hana ʻia ka Ovarian Suppression Therapy.
• ʻO ke ʻoki kino: Ma kēia, ua wehe ʻia nā hunaola kanesa mai ka umauma. Hiki ke hana ʻia kēia ma nā ʻano ʻelua:
• Lumpectomy: Wehe wale ʻana i ka puʻupuʻu kanesa a me kahi liʻiliʻi o nā ʻiʻo olakino a puni ia.
• Mastectomy: Wehe ʻana i ka umauma holoʻokoʻa.

ʻO ke ʻano o ke ʻoki kino kūpono e pili ana i nā mea e like me ka nui a me ka laha ʻana o ke kanesa.

• Lapaʻau Radiation: Ma hope o ke ʻoki ʻana, hiki ke hāʻawi ʻia ka radiation therapy e luku i nā pūnaeho kanesa e waiho ana ma ia wahi.
• Kemoterapi: ʻOi aku ka maikaʻi o nā lāʻau lapaʻau kemoterapi no nā maʻi kanesa e ulu wikiwiki ana. Ulu mālie ke kanesa Luminal A, no laila ʻaʻole pono nā kānaka a pau i ka kemoterapi. Eia nō naʻe, hiki i kekahi poʻe (no ka laʻana, inā ua pālahalaha ke kanesa i nā lymph nodes a inā nui loa ke kanesa) ke pōmaikaʻi mai ka kemoterapi. E haʻi aku kāu kauka maʻi kanesa iā ʻoe inā pono ʻoe i kēia.

I ka manawa pinepine, hāʻawi ʻia ka hui pū ʻana o hoʻokahi a ʻoi aku paha o kēia mau lāʻau lapaʻau. Ma muli o ka ʻike i loko o kāu hōʻike biopsy, e hana kāu kauka i kahi hoʻolālā lapaʻau kūpono iā ʻoe.

He aha ka wānana no ka poʻe me ka maʻi ʻaʻai umauma Luminal A?

Eia kahi nūhou hōʻoluʻolu. Ke hoʻohālikelike ʻia me nā ʻano maʻi ʻaʻai umauma ʻē aʻe, ʻoi aku ka maikaʻi o ka nānā ʻana i ka maʻi ʻaʻai umauma Luminal A.

Eia nō naʻe, pili kāu wānana i ka nui o ke kanesa i ka wā e ʻike ʻia ai, pehea ka wikiwiki o kona ulu ʻana, a inā ua pālahalaha aku i nā ʻāpana ʻē aʻe o ke kino. ʻO ka wikiwiki o ka hoʻomaka ʻana o ka lāʻau lapaʻau, ʻoi aku ka maikaʻi o ka wānana.

Hiki ke ho'ōla piha ʻia ke kanesa umauma Luminal A me ka lāʻau lapaʻau (remission). Eia kekahi, inā ʻike ʻia i ka wā mua (nā hihia o ka wā mua), hiki ke ho'ōla piha ʻia (hiki ke ho'ōla ʻia).

Nā helu ola o ka poʻe i pakele i ke kanesa umauma Luminal A

ʻO ka nui o ke ola ʻana no ʻelima mau makahiki no kēia ʻano maʻi ʻaʻai umauma ma kahi o 95% . ʻO ia hoʻi, he 95 mai loko mai o 100 mau kānaka i ʻike ʻia me kēia maʻi e ola ana ma hope o ʻelima mau makahiki.

Eia nō naʻe, he mau kuhi wale nō kēia mau helu ola e pili ana i nā hopena o nā poʻe ʻē aʻe i loaʻa i ka maʻi ma mua. ʻAʻole lākou e pili pono i kou kūlana. E kamaʻilio me kāu kauka e ʻike pehea e pili ai kēia mau helu i kou kūlana.

Pehea e hōʻemi ai ʻo Luminal A i ka pilikia o ka loaʻa ʻana o ka maʻi ʻaʻai umauma?

ʻAʻole hiki iā mākou ke pale aku i kekahi mau mea pilikia, e like me ka mōʻaukala ʻohana o ka maʻi kanesa. Eia nō naʻe, ʻo ka hana ʻana i kēia mau mea hiki ke kōkua i ka hōʻemi ʻana i kou pilikia holoʻokoʻa no ka maʻi kanesa:

• E pale i ka puhipaka a me ka vaping.
• E ʻai i ka nui o nā huaʻai, nā mea kanu, a me nā palaoa holoʻokoʻa.
• E hoʻonui i ka hana kino. He mea maikaʻi ke hoʻoikaika kino no 30 mau minuke ma ka liʻiliʻi i ka lā.
• E kaupalena i ka inu ʻana i ka waiʻona.
• E mālama i ke kaumaha olakino nou.

Pehea wau e mālama ai iaʻu iho?

He mea maʻamau ka loaʻa ʻana o nā ʻano manaʻo like ʻole ke loaʻa iā ʻoe ka maʻi kanesa. He mea maikaʻi ke manaʻo i nā mea āu e manaʻo nei. I kekahi mau lā, maikaʻi paha ʻoe. I kekahi mau lā, ʻaʻole paha ʻoe makemake e ala aʻe mai kahi moe. He mea nui e hoʻolohe i kou kino. Hiki i kēia mau manaʻo ke kōkua iā ʻoe:

• E ʻai i ka nui o nā huaʻai, nā mea kanu, a me nā palaoa holoʻokoʻa.
• Hiamoe maikaʻi.
• E hoʻokele i ke kaumaha ma o nā hana e like me ka yoga, ka noʻonoʻo ʻana, a i ʻole ke art therapy.
• E hoʻomaha i ka wā e pono ai ʻoe e hoʻomaha.
• E ʻimi i ke kākoʻo mai nā Polokalamu Ola Maʻi Kanesa.
• E kamaʻilio me nā poʻe ʻē aʻe i loaʻa ka maʻi like me ʻoe. Hiki i kēia ke lilo i kumu ikaika nui.

Āhea wau e ʻike ai i kaʻu kauka?

E ʻike pinepine ʻoe i kāu kauka no nā nānā maʻamau. Eia nō naʻe, inā loaʻa iā ʻoe kekahi mau hōʻailona hou , a inā e ʻoi aku ka ʻino o kāu mau hōʻailona i kēia manawa, e hōʻoia e hoʻomaopopo i kāu kauka.

He aha nā nīnau e pono iaʻu e nīnau aku i kaʻu kauka?

Inā loaʻa iā ʻoe ka maʻi ʻaʻai umauma Luminal A, makemake paha ʻoe e nīnau i kāu kauka i kēia mau nīnau:

• He aha ke kahua (pae a kahua paha) o ka maʻi kanesa i loaʻa iaʻu?
• Ua laha anei ke kanesa i nā wahi ʻē aʻe?
• He aha nā lāʻau lapaʻau āu e ʻōlelo ai no ke ʻano o ka maʻi ʻaʻai umauma i loaʻa iaʻu?
• ʻEhia ka lōʻihi o ka mālama ʻana?
• ʻEhia pinepine e pono ai iaʻu e hele mai no nā hoʻokolohua?
• Aia kekahi mau hopena ʻaoʻao o ka lāʻau lapaʻau?

He aha ka leka a mākou e makemake ai e lawe i ka home mai kēia moʻolelo?

ʻO ke kanesa umauma Luminal A kahi ʻano kanesa i loaʻa kahi prognosis maikaʻi loa me ka mālama ʻana . He ʻoiaʻiʻo kēlā. Eia naʻe, ʻo ka ʻike ʻia ʻana he kanesa he hanana hoʻololi ola. I kēlā manawa, hiki iā ʻoe ke ʻike i nā ʻano manaʻo like ʻole, me ka makaʻu a me ke kaumaha. He mea maʻamau ia.

ʻO ka mea nui loa, ʻo ia ke noho mālie, e kiʻi i ka ʻike kūpono, a e hahai i ka ʻōlelo aʻo a kāu kauka. E kiʻi i ke kākoʻo mai kou ʻohana a me kou mau hoaaloha, ka poʻe aloha iā ʻoe. E kamaʻilio me kāu kauka e pili ana i nā makaʻu a hopohopo paha āu e loaʻa ai. Hiki iā ia ke wehewehe i ke ʻano o ka maʻi kanesa āu e loaʻa nei a me nā koho lapaʻau maikaʻi loa nāu.

E hoʻomanaʻo, ʻaʻole ʻoe hoʻokahi. Inā ʻike mua ʻia a mālama pono ʻia, ʻoi aku ka nui o ka manawa e ho'ōla ʻia ai ka maʻi ʻaʻai umauma Luminal A!

`Luminal A, Kanesa ʻUma, Hoʻōla Hormone, Nā Hōʻailona Kanesa, Lapaʻau Kanesa, Ola Kino Wahine, ʻIke Kanesa