I ka wā i hōʻoia ai nā kauka ua loaʻa iā ʻoe ka maʻi ʻaʻai umauma, hiki iaʻu ke noʻonoʻo i kou makaʻu, ka pīhoihoi, a me ke kaumaha. Nui nā nīnau e hiki mai ana i ka noʻonoʻo i ia manawa. Akā, i ka wā e ʻōlelo ai kāu kauka i kahi huaʻōlelo e like me 'HER2-Positive', pono ia e hoʻonui i kou hopohopo. "He aha kēlā huaʻōlelo? Ke manaʻo nei anei ia he koʻikoʻi koʻu kūlana?" He mea maʻamau ka hiki ʻana mai o hoʻokahi tausani mau mea i ka noʻonoʻo. No laila, i kēia lā e kamaʻilio mākou e pili ana i ke ʻano o kēia maʻi ʻaʻai umauma 'HER2-Positive', kona manaʻo, a me nā lāʻau lapaʻau no ia mea ma ke ʻano maʻalahi loa e hiki ai iā ʻoe ke hoʻomaopopo.
He aha ka 'HER2'?
I ka ʻōlelo maʻalahi, he protein ʻo HER2 e kōkua ana i ka ulu ʻana o nā hunaola umauma i loko o ko kākou kino. ʻO kona inoa piha ʻo "Human Epidermal Growth Factor Receptor 2". Aia kēia protein i loko o nā hunaola umauma o ke kanaka olakino ma kahi nui i kāohi ʻia. Kōkua ia i nā hunaola e māhele a ulu ma ke ʻano maʻamau.
Eia nō naʻe, i kekahi mau maʻi ʻaʻai umauma, ma muli o kahi kīnā i loko o ka gene e hana ai i ka protein HER2, hana nui ʻia kēia protein. Ua like ia me ke hehi ʻana ma luna o ka accelerator o ke kaʻa. A laila, me he mea lā e holo wikiwiki ana ke kaʻa, hoʻomaka kēia mau hunaola kanesa e māhele a ulu koke, me ke kaohi ʻole. ʻO ke kumu nui e ʻoi aku ai ka ʻino o ke kanesa, ʻo ia ka hana nui ʻana o ka protein.
No laila, inā ' HER2-positive ' kou maʻi kanesa, ʻo ia hoʻi he keu o kēia protein ulu i kapa ʻia ʻo HER2 ma luna o ka ʻili o kāu mau hunaola kanesa.
Pehea e ʻike ai inā he HER2-positive ia?
Ke kānalua ʻoe he maʻi ʻaʻai umauma kou, e paipai paha kāu kauka i kahi biopsy. E like me kāu e hoʻomanaʻo nei, pili kēia i ka lawe ʻana i kahi ʻāpana liʻiliʻi o ka ʻiʻo a hoʻouna iā ia i kahi lab e hoʻāʻo ʻia. A laila e nānā ʻia kēia hāpana ʻiʻo e hoʻoholo i ke ʻano kikoʻī o ka maʻi ʻaʻai.
ʻO ka mea nui e nānā ʻia ma kēia hoʻāʻo ʻana, ʻo ia ke kūlana HER2. Eia kekahi, ua nānā ʻia kekahi mea nui. ʻO ia hoʻi, inā he ʻano maʻalahi ke kanesa i nā hormones. ʻO ia hoʻi, inā ulu ke kanesa ma muli o nā hormones `(Estrogen)` a me `(Progesterone)`. Ma hope o ka nānā ʻana i kēia mau mea a pau, hoʻoholo ke kauka i ke ʻano lapaʻau kūpono a holomua loa nāu.
E wehewehe iki aku kākou e pili ana i kā kākou e hoʻāʻo nei.
| Māka | He aha ka ʻōlelo a kēlā? |
|---|---|
| Kūlana HER2 | Hoʻāʻo ʻia nā hunaola kanesa e ʻike inā he nui loa ka protein HER2 (maikaʻi) a ʻaʻole paha (maikaʻi ʻole). Inā maikaʻi, ʻo ia hoʻi ke kōkua nei kēia protein i nā hunaola kanesa e ulu wikiwiki. |
| Kūlana o ka mea hoʻokipa hormone | Nānā lākou e ʻike inā loaʻa i nā hunaola kanesa nā mea loaʻa no nā hormones estrogen a progesterone paha. Inā maikaʻi kēia mau mea, kōkua kēlā mau hormones i ka ulu ʻana o ke kanesa. |
E hoʻoholo nā hopena o kēia mau hoʻokolohua i ke ʻano o ka maʻi kanesa āu. No ka laʻana, HER2-positive a i ʻole Hormone Receptor-negative. He mea nui kēia ʻike a pau i ke kōkua ʻana iā ʻoe e hoʻomohala i kāu hoʻolālā lapaʻau .
ʻO wai ka mea i loaʻa i ka maʻi kanesa HER2-positive? He mea weliweli anei ia?
Hiki ke loaʻa ka maʻi ʻaʻai umauma HER2-positive i nā wahine a me nā kāne, a he kākaʻikahi loa i nā kāne. ʻOi aku ka maʻamau i nā wahine ma lalo o 50 mau makahiki. ʻAʻole ʻike ʻia ke kumu pololei.
I kēia manawa, e hele kākou i ka nīnau nui loa ma kou manaʻo: He mea weliweli anei kēia?
ʻO ka ʻoiaʻiʻo, ʻoi aku ka nui o ka ulu ʻana o nā maʻi kanesa HER2-positive. ʻO ke ʻano kēia, ʻoi aku ka nui o ke ʻano o kēia mau hunaola kanesa e māhele a laha koke paha.
Akā, mai hopohopo! ʻO kēia ka mea e pono ai ʻoe e hoʻomanaʻo. ʻAe, hiki i kēia ʻano maʻi kanesa ke wikiwiki. Akā, ua hoʻomohala ʻia nā lāʻau lapaʻau kūpono loa a kikoʻī i kēia lā i kūpono no ia. No laila, ʻaʻohe kumu e makaʻu ai i ka huaʻōlelo "wikiwiki".
Ka mālama ʻana a me ka manaʻolana no ka ho'ōla ʻana
ʻO kēia ka nūhou maikaʻi loa ma kēia ʻatikala. Ma kahi o 20 mau makahiki i hala aku nei, ua manaʻo ʻia ka maʻi ʻaʻai umauma HER2-positive he maʻi paʻakikī a koʻikoʻi hoʻi e mālama. Akā me ka holomua o ka ʻepekema lapaʻau, ua loli loa ke kūlana i kēia lā.
Ua ʻike nā kānaka ʻepekema i kekahi mau lāʻau lapaʻau kūikawā e hiki ke kuhikuhi a ālai i ka hana o kēia protein HER2. Ua kapa ʻia kēia he " targeted therapy.")`. I mea e pololei ai, hele pololei kēia mau lāʻau i ka protein HER2 i loaʻa ma ke keu, e ālai ana i ka hōʻailona e loaʻa ana i nā hunaola kanesa e "ulu wikiwiki." Ua like kēia me ke kau ʻana i nā paleki ma kahi kaʻa e holo wikiwiki ana.
Ma muli o kēia mau lāʻau lapaʻau i hoʻolālā ʻia, ua kiʻekiʻe loa ka manawa e ho'ōla loa ʻia ai ke kanaka me ka maʻi ʻaʻai umauma HER2-positive, e like me nā helu ho'ōla no nā maʻi ʻaʻai maʻamau e hilinaʻi ana i ka hormone.
He aha ka mea e hana ʻia ma hope o ka lāʻau lapaʻau?
Ma hope o ka pau ʻana o ka lāʻau lapaʻau, e hoʻomau kāu kauka i ka nānā ʻana iā ʻoe. I kekahi manawa, hiki ke hoʻi hou mai ka maʻi kanesa a laha paha i nā wahi ʻē aʻe o ke kino. Inā hana ʻia kēia, e hana hou kāu kauka i kahi biopsy. ʻO kēia no ka mea hiki ke loli ke ʻano o ke kanesa i kekahi manawa i ka hala ʻana o ka manawa. No ka laʻana, hiki i kahi kanesa i HER2-positive ma mua ke hoʻi hou mai a lilo i HER2-negative. No laila, hoʻokumu mau ʻia ka lāʻau lapaʻau ma ke kūlana hou loa.
No laila, e hoʻopau i kou makaʻu. ʻAe, he mea weliweli ka huaʻōlelo kanesa. Akā, he maʻi hiki ke mālama ʻia a hoʻōla ʻia ʻo HER2 -Positive i kēia lā.
Leka Lawe-Home
- ʻO ke kanesa umauma HER2-positive ka wā e hana nui ai nā hunaola kanesa i kahi protein (HER2) e hoʻolalelale ai i ka ulu ʻana.
- Hoʻomaopopo ʻia kēia kūlana ma ka nānā ʻana i kahi hāpana ʻiʻo mai kāu biopsy.
- ʻOiai ke ulu wikiwiki nei kēia ʻano maʻi ʻaʻai, ʻaʻohe pono e makaʻu iā ia.
- I kēia mau lā, ua holomua loa nā ʻano lapaʻau i hoʻolālā ʻia no kēia kumu. ʻO ka hopena, kiʻekiʻe loa ka manawa e hoʻōla ai.
- E kamaʻilio ākea me kāu kauka e pili ana i nā nīnau, nā makaʻu, a i ʻole nā kānalua āu e loaʻa ai. Ma laila ʻoe e loaʻa ai ka ʻike pololei loa a me ka hōʻoluʻolu maikaʻi loa.
- ʻAʻole ʻoe hoʻokahi. Me ka noʻonoʻo ikaika a me ka mālama kūpono, hiki iā ʻoe ke lanakila ma luna o kēia pilikia.
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