Ua ʻike anei ʻoe i kēia ʻano maʻi ʻaʻai umauma i kapa ʻia ʻo ER+? (Estrogen Receptor-Positive Breast Cancer - ER+)

Ua lohe paha ʻoe i ke kanesa o ka umauma? Malia paha ua loaʻa i kekahi o kou mau hoaaloha. Nui nā ʻano kanesa o ka umauma. I kēia lā e kamaʻilio mākou e pili ana i kekahi o lākou. ʻO ia ka maʻi kanesa o ka umauma ER+ (ER maikaʻi) . ʻOiai paha he paʻakikī iki ka inoa, e wehewehe maʻalahi kākou.

He aha ka maʻi ʻaʻai umauma ER+?

I ka ʻōlelo maʻalahi, ʻo ka maʻi ʻaʻai umauma ER+ kahi ʻano maʻi ʻaʻai umauma. E hoʻomanaʻo, he hormone i kapa ʻia ʻo estrogen i loko o nā wahine i loko o ko lākou kino. Kōkua kēia hormone i nā mea he nui. Eia nō naʻe, i kekahi manawa kōkua pū kēia hormone estrogen i nā hunaola kanesa e ulu. No laila, ʻo nā hunaola kanesa umauma e ulu ana ma muli o ka hormone estrogen ʻo ia ka mea a mākou e kapa nei he maʻi ʻaʻai umauma ER+. ʻO 'ER' ke kū nei no Estrogen Receptor . ʻO ia hoʻi, aia i kēia mau hunaola kanesa nā wahi e hiki ai i ka estrogen ke 'hoʻopili'. Nānā nā kauka i ka pae o kēia mau mea loaʻa estrogen e hoʻolālā i ka mālama ʻana. ʻO ka maʻamau, hoʻohana ʻia ke ʻoki kino a me ka hormone therapy ma ke ʻano he mau lāʻau lapaʻau no kēia. Kapa pū kekahi poʻe i kēia he 'maʻi ʻaʻai umauma estrogen positive'.

Pehea ka maʻamau o ka maʻi ʻaʻai umauma ER+?

ʻOi aku ka maʻamau o kēia ma mua o kou manaʻo. ʻO ka hapa nui o ka poʻe i loaʻa i ka maʻi ʻaʻai umauma, ma kahi o 70 mai ka 100, loaʻa iā lākou kēia ʻano maʻi ʻaʻai i kapa ʻia ʻo ER+. Hoʻokomo pū kēia i nā kāne, no ka mea hiki i nā kāne ke loaʻa i ka maʻi ʻaʻai umauma, akā ʻaʻole ia he mea maʻamau. No laila, ʻaʻole kēia he mea i lohe ʻole ʻia.

He aha nā hōʻailona o ka maʻi ʻaʻai umauma ER+?

ʻO ka maʻamau, ʻo ke kanaka me ka maʻi ʻaʻai umauma ER+ e hōʻike i nā hōʻailona like me kekahi me ka maʻi ʻaʻai umauma. E nānā kākou i ke ʻano o lākou:

• Ke ʻike nei i kahi loli i ka nui, ke ʻano, a i ʻole ke ʻano o kekahi o kou mau umauma . Malia paha he ʻokoʻa kekahi umauma mai kekahi.
• Ua paʻa ka lima i kahi puʻupuʻu a mea puʻupuʻu paha. Hiki i kēia ke liʻiliʻi e like me ka pī.
• He manaʻo mānoanoa a paʻa paha ma ka umauma a i ʻole ka ʻāpana lima. Pono ʻoe e hopohopo nui inā loaʻa kēia i loko o kou pōʻaiapuni mahina.
• He loli i ke ʻano a i ʻole ke ʻano o ka ʻili o ka umauma a i ʻole ka nipple. Hiki ke ʻike ʻia ka ʻili he dimpled, puckered, unahi, a pehu paha. Hiki ke ʻulaʻula a ʻeleʻele paha ma mua o ke koena o ka umauma.
• Ke manaʻo nei i kahi paʻakikī ma lalo o ka ʻili, e like me kahi ʻāpana kinikini .
• He wai koko a moakāka paha e puka mai ana mai loko mai o ka nipple.

Inā manaʻo ʻoe he mau hōʻailona kēia iā ʻoe, mai makaʻu e ʻike i ke kauka. ʻO ka wikiwiki o kou ʻike ʻana, ʻo ka maʻalahi ka mālama ʻana.

He aha ke kumu o ka maʻi ʻaʻai umauma ER+?

ʻAe, i kēia manawa e nānā kākou pehea e hana maoli ai kēia. I loko o nā pūnaewele o ko kākou kino, aia nāAia nā mea i kapa ʻia he mau mea loaʻa hormone. Ua like kēia me nā puka liʻiliʻi, he ʻano protein. Hiki i ka hormone estrogen i loko o ko kākou koko ke hoʻopaʻa i kēia mau mea loaʻa. I loko o nā pūnaewele olakino, kōkua ka estrogen i nā pūnaewele e hana a ulu maʻamau. He mea maʻamau kēlā.

Eia nō naʻe, i loko o ke kanesa umauma ER+, hoʻopaʻa kēia hormone estrogen i nā protein i loko o nā hunaola kanesa, e hoʻoulu ai i kēlā mau hunaola kanesa e ulu nui aʻe. E noʻonoʻo e like me ka estrogen e like me ka 'mea hoʻouluulu' no nā hunaola kanesa. I kekahi manawa, ʻaʻole wale ka estrogen, akā ʻo kekahi hormone i kapa ʻia ʻo progesterone e kōkua pū i ka ulu ʻana o kēia mau hunaola kanesa. Kāhea mākou i kēlā mau kanesa me nā pae progesterone kiʻekiʻe he PR-positive (PR+) he kanesa umauma. Hiki i kekahi mau kanesa ke lilo i ER+ a me PR+.

He aha nā kumu pilikia no kēia?

Aia kekahi mau mea pilikia e hiki ke hoʻopilikia i ka ulu ʻana o ka maʻi ʻaʻai umauma ER+. E nānā kākou i ke ʻano o lākou.

Nā kumu pilikia no nā wahine:

No nā wāhine, ʻo ka pilikia nui ka lōʻihi o ka hoʻopili ʻana i ka hormone estrogen . ʻO ia hoʻi, e mau ana ke kiʻekiʻe o nā pae estrogen i loko o ke kino no ka manawa lōʻihi. E nānā kākou pehea e hana ai:

• Ka wā ʻōpiopio mua (ka hoʻomaka mua ʻana o ka menstruation).
• Ka hoʻopaneʻe ʻana o ka menopause .
• Ka lohi o ka hānau ʻana o nā keiki a i ʻole ka loaʻa ʻole o nā keiki.
• ʻO ka lawe ʻana i ka lāʻau lapaʻau hormone (ʻoi aku ka poʻe i loaʻa ka estrogen) no nā hōʻailona e kū mai ana ma hope o ka menopause.

Nā kumu pilikia no nā kāne:

No nā kāne, pili kēia pilikia me nā pae kiʻekiʻe o ka estrogen ma mua o ka maʻamau a me nā pae haʻahaʻa o ka testosterone i loko o ko lākou kino. Ua kapa ʻia kēia he hormonal imbalance . Eia kekahi mau laʻana:

• Ka momona nui .
• ʻO ka maʻi diabetes (Diabetes Mellitus) .
• Nā kūlana e like me ka cirrhosis o ke ake .

Pehea e ʻike pololei ʻia ai ka maʻi ʻaʻai umauma ER+?

Inā kānalua ʻoe he maʻi ʻaʻai umauma kou, e hana mua kāu kauka i kahi biopsy umauma . Pili kēia i ka lawe ʻana i kahi laʻana liʻiliʻi o ka ʻiʻo mai ka puʻupuʻu maʻi ʻaʻai. A laila hoʻouna ʻia kēia laʻana i kahi keʻena hoʻokolohua. Ma laila, e nānā kahi kauka lapaʻau , he kauka loea i ka nānā ʻana i nā ʻiʻo, i nā ʻiʻo e ʻike inā he mau mea loaʻa hormone.

Inā ʻo ka hopena o ka hoʻāʻo he Hormone Receptor-Positive (HR+) , ʻo ia hoʻi, ke kōkua nei ka estrogen, progesterone, a i ʻole kēia mau hormones ʻelua i ka ulu ʻana o nā hunaola kanesa. ʻO ER+ kekahi ʻāpana o HR+. ʻO ia hoʻi, aia nā mea loaʻa estrogen. No lailaInā hōʻike nā hoʻokolohua ʻaʻole kiʻekiʻe nā pae estrogen, ua manaʻo ʻia ka maʻi kanesa o ka umauma he estrogen receptor-negative (ER-negative) .

He aha nā lāʻau lapaʻau no ka maʻi ʻaʻai umauma ER+?

Hoʻohana nā kauka i kekahi mau ʻano hana nui i ka mālama ʻana i ka maʻi ʻaʻai umauma ER+. ʻO kēia mau mea:

• ʻO ke ʻoki ʻana i ke kanesa o ka umauma : Pili kēia i ka wehe ʻana i nā puʻupuʻu kanesa.
• Lapaʻau radiation : Hoʻohana ʻia nā kukuna ikehu kiʻekiʻe e luku i nā hunaola kanesa.
• Chemotherapy : Ma kēia lāʻau lapaʻau, hoʻohana ʻia nā lāʻau lapaʻau e pepehi i nā hunaola kanesa a kāohi paha i ko lākou ulu ʻana.
• Nā lāʻau lapaʻau hormone : He mea nui loa kēia no nā maʻi ʻaʻai ER+. ʻElua mau ʻano hana no kēia:
• Nā mea hoʻopaʻa Aromatase : Hana kēia mau lāʻau lapaʻau ma ka hoʻemi ʻana i ka hana ʻana o ka hormone estrogen i loko o kou kino, ʻo ia hoʻi, ua nele nā ​​​​​​pūnaewele kanesa i ka meaʻai.
• Nā Modulators Receptor Estrogen Selective (SERMs) : Hana kēia mau lāʻau lapaʻau ma ke kāohi ʻana i ka hormone estrogen mai ka hoʻopili ʻana i nā hunaola kanesa. Kōkua pū lākou i ka hōʻemi ʻana i ka pilikia o ka hoʻi hou ʻana mai o ke kanesa.

E loiloi ke kauka i kou kūlana a hoʻoholo i kahi o kēia mau lāʻau lapaʻau e kūpono iā ʻoe a pehea e hāʻawi ai iā lākou.

He aha nā hopena ʻaoʻao o ka lāʻau lapaʻau?

E like me nā lāʻau lapaʻau a pau, hiki i kēia mau lāʻau lapaʻau ke loaʻa kekahi mau hopena ʻaoʻao. Mai hopohopo, e wehewehe mua nā kauka i kēia mau mea a pau iā ʻoe.

ʻO nā hopena ʻaoʻao maʻamau o ka chemotherapy a me ka radiation therapy :

• Manaʻo luhi loa (Fatigue)
• Ka luaʻi a me ka luaʻi

Eia kekahi, hiki ke ʻike ʻia nā hopena ʻaoʻao i ka wā o ka hormone therapy :

• ʻEha a ʻoʻoleʻa paha nā hono
• Luhi
• Piʻi ke kaumaha
• Ka emi ʻana a i ʻole ka nalowale o ka hoihoi i ka moekolohe
• ʻĀlohilohi wela - he manaʻo o ka wela e puka mai ana mai loko mai o ke kino .
• Nā umauma palupalu a pehu paha

Inā ʻoe e mālama ʻia nei no ka maʻi ʻaʻai umauma ER+, e nīnau i kāu kauka e pili ana i ka mālama palliative . Hiki i kēia ke kōkua iā ʻoe e hoʻokele i nā hōʻailona o kou maʻi ʻaʻai a me nā hopena ʻaoʻao o kāu lāʻau.

He aha ka helu ola no ka maʻi ʻaʻai umauma ER+?

He nīnau kēia a ka poʻe he nui e nīnau ai. Wahi a ka ʻikepili mai ka National Cancer Institute (NCI) , ma ka laulā, ʻelima mau makahiki ma hope o ka ʻike ʻia ʻana o nā wahine me ka maʻi ʻaʻai umaumaUa ola ma mua o 90% o nā kānaka. He nūhou maikaʻi maoli kēia. Eia naʻe, ʻaʻole i hāʻawi ka NCI i ka ʻikepili kaʻawale e pili ana i ka nui o ke ola no nā kāne me ka maʻi ʻaʻai ER+.

I ka noʻonoʻo ʻana i nā helu ola, he mea nui e hoʻomanaʻo he mau helu kēia i hoʻokumu ʻia ma nā ʻike o kahi hui nui o ka poʻe . Eia kekahi, he mau kuhi paha ia e pili ana i nā kūlana i loaʻa i nā makahiki he nui i hala. Ke holomua nei nā lāʻau lapaʻau i kēlā me kēia lā. No laila, ʻoi aku ka maikaʻi o ke kamaʻilio ʻana me kāu kauka e pili ana i kou kūlana a me nā mea āu e manaʻo ai.

Hiki i ke kanesa ER+ ke hoʻi hou mai ma hope o ka mālama ʻia ʻana?

ʻOiai ua manaʻo ʻia ʻo ka maʻi ʻaʻai umauma ER+ ʻaʻole i ʻoi aku ka ikaika ma mua o kekahi mau ʻano maʻi ʻaʻai ʻē aʻe, aia kahi pilikia o ka hoʻi hou ʻana ma hope o ka mālama ʻana. Hiki ke loaʻa kēia pilikia ʻoiai inā ʻike mua ʻia ka maʻi ʻaʻai ER+ a mālama ʻia me ka maʻi ʻaʻai ER+ haʻahaʻa. Inā hopohopo ʻoe e hoʻi hou mai paha kāu maʻi ʻaʻai, e kamaʻilio me kāu kauka maʻi ʻaʻai e pili ana i kou pilikia pilikino a me nā mea hiki iā ʻoe ke hana e hōʻemi i kou pilikia.

Pehea ʻoe e mālama ai iā ʻoe iho me ka maʻi ʻaʻai umauma ER+?

I ka wā e noho ana me ka maʻi ʻaʻai umauma ER+, he mea nui e mālama pono iā ʻoe iho. Eia kekahi mau manaʻo e hiki ke kōkua iā ʻoe:

• E hoʻomaha lawa. Hiki i ka maʻi ʻaʻai umauma a me kāna lāʻau lapaʻau ke luhi loa. E hoʻomanaʻo e hoʻomaha i ka wā e luhi ai ʻoe, ʻaʻole wale i ka wā āu e makemake ai.
• E ʻai pono. Hiki ke loli kou makemake ma muli o ka lāʻau lapaʻau. ʻO ka ʻai ʻana e komo pū ana me nā huaʻai, nā mea kanu, ka protein lean, a me nā palaoa olakino e kōkua iā ʻoe e noho ikaika i ka wā o ka lāʻau lapaʻau.
• E hoʻokele i ke kaumaha. He nui ke kaumaha o ka hoʻoponopono ʻana i ka maʻi kanesa. He ala maikaʻi loa ka hoʻoikaika kino e kōkua ai i kēia. Hiki iā ʻoe ke hana i kekahi mea mai ka hele wāwae i kēlā me kēia lā a i ke komo ʻana i nā papahana hoʻoikaika kino.
• E kiʻi i ke kākoʻo. He mea ola ʻoe i ka maʻi ʻaʻai umauma, a hoʻomaka kēlā i ka lā i ʻike ʻia ai ʻoe. E nīnau i kāu kauka e pili ana i nā papahana ola i ka maʻi ʻaʻai . Hiki i kēia mau mea ke kōkua iā ʻoe e hoʻokele i nā pilikia o ka noho ʻana me ka maʻi ʻaʻai umauma.

Āhea ʻoe e pono ai e ʻike i ke kauka i ka wā hikiwawe loa?

Inā manaʻo ʻoe e ʻoi aku ka ʻino o kāu mau hōʻailona, ​​a inā paha e loaʻa iā ʻoe nā hōʻailona hou, e like me ka ʻeha a nāwaliwali paha ma nā wahi ʻē aʻe o kou kino, e ʻike koke i kāu kauka.

He aha nā nīnau koʻikoʻi e nīnau aku ai i ke kauka?

Ke ʻike ʻoe i kāu kauka, mai makaʻu e nīnau i kāu mau nīnau. Eia kekahi mau nīnau hiki iā ʻoe ke nīnau:

• He aha ke ʻano o ka lāʻau lapaʻau āu e paipai mai nei iaʻu?
• E pono anei iaʻu ka chemotherapy a me ka radiation therapy, a i ʻole e lawa wale ka hormone therapy?
• Pono anei au e lawe i ka hormone therapy no ke koena o koʻu ola?
• He aha nā hopena ʻaoʻao o kēia mau lāʻau lapaʻau? He aha kaʻu e hana ai e hōʻemi iā lākou?
• He aha koʻu mau manaʻolana e hoʻōla hou ai?

Ma hea e laha ai ka maʻi ʻaʻai umauma ER+?

Hiki i ke kanesa umauma ke laha i kekahi manawa i nā wahi ʻē aʻe o ke kino. Hoʻokomo pū kēia i nā ʻōpū e like me nā māmā, ka lolo, nā iwi, a me ke akepaʻa . ʻO ka kanesa umauma ER+ ka mea e pili ana i kahi 70% o nā kanesa umauma āpau, no laila he mea nui e makaʻala i kēia laha ʻana.

ʻO ka mea hope loa, kekahi mau mea e hoʻomanaʻo ai

ʻAe, e hōʻuluʻulu kākou i nā kumu nui a mākou i kamaʻilio ai i kēia lā.

ʻO ke kanesa umauma ER+ kahi ʻano kanesa e ulu ana ma muli o ka hormone estrogen. ʻOiai ke kōkua maʻamau nei kēia hormone i ka ulu ʻana o nā cell, hāʻawi pū ia i ka 'meaʻai' i nā cell cancer.

Hoʻāʻo nā kauka i nā pae o ka estrogen i loko o nā hunaola kanesa umauma a hoʻolālā i ka lāʻau lapaʻau e like me ia. Hana ka lāʻau lapaʻau hormone, ma ke ʻano kūikawā, e hōʻemi i ka hopena o kēia hormone estrogen i nā hunaola kanesa.

Inā loaʻa iā ʻoe ka maʻi ʻaʻai umauma ER+, mai makaʻu e kamaʻilio me kāu kauka . E hoʻolohe pono a hoʻomaopopo i kāu mau koho lapaʻau a pehea e kōkua ai kēlā me kēia lapaʻau iā ʻoe. ʻAʻole ʻoe hoʻokahi, a he nui nā kauka a me nā lawelawe kākoʻo e loaʻa ana e kōkua iā ʻoe.

Mai poina e hiki ke hoʻomalu maikaʻi ʻia kēia maʻi me ka ʻike mua ʻana a me ka mālama kūpono.

ʻO ka ER+ Ka maʻi ʻaʻai umauma, Estrogen, Nā hōʻailona o ke kanesa umauma, Hormone Therapy, Lapaʻau ʻana i ke kanesa, Ola kino o nā wāhine, Estrogen Receptor-Positive Ka maʻi ʻaʻai umauma