Ke maʻi pinepine nei ʻoe? I kekahi manawa, ʻoiai he anu liʻiliʻi, lōʻihi ka manawa e hoʻōla ai, a i ʻole ke manaʻo mau nei ʻoe he nāwaliwali? ʻO kekahi kumu o kēia mau mea, ʻo ia ka emi ʻana o kahi ʻano koko keʻokeʻo i kapa ʻia ʻo lymphocytes, e like me nā koa i loko o kou kino e hakakā ana i nā maʻi. Ua kapa nā kauka i kēia maʻi ʻo 'lymphopenia.' No laila, e kamaʻilio kākou e pili ana i kēia me nā kikoʻī hou aku i kēia lā, ʻeā? ʻAʻole ia he mea e makaʻu ai, he mea nui e makaʻala.
He aha ka lymphopenia? E hoʻomaopopo maʻalahi kākou!
I ka ʻōlelo maʻalahi, ʻo ka lymphopenia kahi kūlana kahi i emi ai ka nui o nā lymphocytes i loko o kou koko ma mua o ka maʻamau. I kēia manawa ke noʻonoʻo nei paha ʻoe i ke ʻano o kēia mau lymphocytes.
Aia kekahi ʻano o nā hunaola koko keʻokeʻo i loko o ko kākou koko. ʻO kēlā mau hunaola koko keʻokeʻo nā mea e pale aku iā kākou ma ke kaua ʻana i nā huakini e komo i loko o ko kākou kino, ʻo ia hoʻi, nā bacteria a me nā virus e hoʻoulu ai i nā maʻi. Ua like ia me kahi pūʻali koa liʻiliʻi i loko o ko kākou kino. Ma waena o 20% a me 40% o kēia mau hunaola koko keʻokeʻo he ʻano hunaola kūikawā kēia i kapa ʻia ʻo Lymphocytes.
ʻO nā hana nui o kēia mau pūnaewele lymph (Lymphocytes):
- Ke kaua nei i nā germs (viruses, bacteria, parasites, fungi) e komo i ke kino.
- Ka luku ʻana i nā pūnaewele ʻano ʻē, e like me nā pūnaewele maʻi ʻaʻai.
- Hana ma ke ʻano he ʻāpana koʻikoʻi o ka ʻōnaehana pale o ko mākou kino.
ʻEkolu mau ʻano nui o nā lymphocytes:
- Nā lymphocytes T a i ʻole nā T-cell: Kōkua kēia i ka luku pololei ʻana i nā pūnaewele i loaʻa i ka maʻi a me nā cell cancer.
- Nā lymphocytes-B a i ʻole nā pūnaewele-B: ʻO kēia nā mea e hana ai i nā antibodies. Kōkua kēia mau antibodies i ka ʻike a me ka hoʻouka ʻana i nā germs.
- Nā pūnaewele pepehi kanaka kūlohelohe (nā pūnaewele NK): Kōkua pū kēia i ka luku ʻana i nā pūnaewele i loaʻa i ka maʻi a me nā pūnaewele maʻi kanesa.
No laila, ke emi ka helu o nā lymphocytes, ʻo ia hoʻi, ke kū mai kahi maʻi i kapa ʻia ʻo lymphopenia, e emi ana ka hiki o ko mākou kino ke pale aku i nā maʻi. A laila, hiki ke ulu maʻalahi nā maʻi, a ʻo nā maʻi e ulu ana e lōʻihi ka manawa e ho'ōla ai.
Ua kapa ʻia ʻo Lymphopenia ʻo lymphocytopenia a me lymphocytic leukopenia. Pili ʻo Leukopenia i ka emi ʻana o nā keʻokeʻo koko ma ke ʻano laulā. Pili ʻo "Lymphocytic" leukopenia i ka emi ʻana o nā lymphocytes ma ke ʻano kūikawā.
Ehia ka nui o nā lymphocytes e pono ai ke loaʻa maʻamau?
ʻOkoʻa ka helu o kēia mau pūnaewele lymph (Lymphocytes) ma waena o nā pākeke a me nā keiki.
- I nā pākeke: ʻO ka maʻamau, pono ma waena o 1,000 a me 4,800 mau lymph cell i kēlā me kēia microliter o ke koko. ʻO ka Lymphopenia ka wā i emi ai kēia helu ma mua o 1,000.
- Nā keiki:ʻO ka maʻamau, aia ma waena o 3,000 a me 9,500 mau helu lymphocyte no kēlā me kēia microliter o ke koko. Hiki ke loli kēia pae haʻahaʻa ma muli o ka makahiki o ke keiki. No ka laʻana, inā he emi ka helu lymphocyte o kahi keiki ma lalo o 2 mau makahiki ma mua o 3,000, ua manaʻo ʻia he lymphopenia.
Hiki ke ʻokoʻa iki kēia mau waiwai mai ka hale hana a i ka hale hana, no laila ʻoi aku ka maikaʻi o ka hoʻohālikelike ʻana iā lākou i nā waiwai awelika i kāu hōʻike.
He aha nā hōʻailona o ka lymphopenia?
ʻO ka mea maikaʻi loa, inā he lymphopenia wale nō kāu, ʻo ia hoʻi ka nele o nā lymphocytes, ʻaʻohe ou hōʻailona pinepine. Eia nō naʻe, inā he maʻi kumu e hoʻohaʻahaʻa ai i ka helu lymphocyte, loaʻa paha iā ʻoe nā hōʻailona e pili ana i kēlā maʻi. A i ʻole he mau maʻi pinepine paha kāu.
ʻO kekahi o nā hōʻailona e hiki ke ʻike ʻia:
- kuni
- Kuke
- Ihu wai
- ʻO ka ʻili ʻili a i ʻole nā maʻi ʻili ʻē aʻe
- Nā ʻōpū lymph pehu
- Pehu hui
- Nā ʻeha waha
- Melemele o nā maka a me ka ʻili (Jaundice)
- Ka nui o ka spleen a i ʻole ka splenomegaly
Inā loaʻa iā ʻoe ka lymphopenia koʻikoʻi, hiki iā ʻoe ke loaʻa pinepine i nā maʻi, a i ʻole e lōʻihi ka manawa e ho'ōla ai nā maʻi. Eia nō naʻe, me ka lymphopenia ʻoluʻolu, ʻaʻole paha ʻoe e loaʻa i kekahi mau hōʻailona.
No ke aha e emi ai kēia mau helu lymphocyte? He aha nā kumu?
Aia kekahi mau kumu like ʻole e loaʻa ai iā ʻoe nā lymphocytes haʻahaʻa. I kekahi manawa hiki ke hānau ʻia ʻoe me kahi maʻi e hoʻoulu ai i kēia maʻi. A i ʻole e ulu paha ia ma hope o ke ola. Ma muli o ke kumu, hiki i ka lymphopenia ke ola a pau (mau) a i ʻole e hoʻopau koke ʻia (ʻoi).
ʻO kekahi o nā kumu nui o ka lymphopenia he mau maʻi, kekahi mau lāʻau lapaʻau, a me nā hemahema meaʻai.
1. Ma muli o nā maʻi
ʻO nā maʻi i hoʻokumu ʻia e nā virus, bacteria, parasites, a me nā fungi hiki ke hoʻemi i ka nui o nā lymphocytes. Eia kekahi mau laʻana:
- ʻO ka maʻi HIV a me ka maʻi AIDS
- ʻO ka maʻi palū (flu) - ʻo ia hoʻi, ma ka ʻōlelo maʻamau, ka maʻi palū.
- COVID-19
- Hepatitis - kahi maʻi o ke akepaʻa
- Malaria
- Ka maʻi ahulau
- Pneumonia
- ʻO ka maʻi puʻupuʻu
Ke hiki mai ia ʻano maʻi, hiki ke hoʻopau ʻia nā pūnaewele lymph o ke kino (Lymphocytes) e hakakā iā lākou, a i ʻole e kāohi ʻia paha kā lākou hana ʻana no kekahi manawa.
2. Ma muli o nā hemahema o ka meaʻai
ʻO kēia ke kumu nui o ka lymphopenia ma ka honua holoʻokoʻa. E lawe i ka lawa mai kāu meaʻai.ʻO ka nele i ka meaʻai, a i ʻole ka nele o nā huaora a me nā minelala e like me ka huaora B12, ka waikawa folic, a i ʻole ka zinc, hiki ke hoʻopilikia i ka hana ʻana o nā lymphocytes. Me ko mākou nohona paʻahana, i kekahi manawa ʻaʻole mākou e nānā pono i ka mea a mākou e ʻai ai. Inā hoʻomau nā mea e like me kēia, hiki ke loaʻa kēia ʻano kūlana.
3. Ma muli o nā kūlana hoʻoilina
Aia kekahi mau maʻi hoʻoilina laha ʻole i hoʻoili ʻia mai nā mākua a i nā keiki. Hiki i kēia mau maʻi ke hoʻemi i ka nui o nā lymphocytes. ʻO kekahi mau laʻana:
- ʻAtaxia-telangiectasia
- ʻO ka hemahema pale maʻamau
- ʻO ka maʻi DiGeorge
- ʻO ka maʻi immunodeficiency i hui pū ʻia (SCID)
- ʻO ka maʻi Wiskott-Aldrich
He mea paʻakikī iki kēia, akā he mau kūlana kakaikahi loa kēia.
4. Ma muli o nā maʻi Autoimmune
ʻO nā maʻi Autoimmune ka wā e hoʻouka hewa ai ko kākou ʻōnaehana pale ponoʻī, ka ʻōnaehana e pale aku iā kākou mai ka maʻi, i kā kākou mau hunaola olakino ponoʻī. E noʻonoʻo, hele hewa ka ʻōnaehana pale o kou kino a hoʻomaka e hakakā i kāna mau hunaola maikaʻi ponoʻī. ʻO ia ke kumu o kēia. Hiki i nā lymphocytes ke lilo i waena o nā hunaola e hoʻouka.
ʻO kekahi mau maʻi like:
- Lupus
- ʻO ka Sarcoidosis
- ʻO ka maʻi ʻaʻai
- ʻO ka Rheumatoid arthritis - ʻo ia hoʻi ka mumū o nā hono
5. Ma muli o nā maʻi koko a me ke kanesa
E like me nā pūnaewele ʻē aʻe i loko o ke koko, hana ʻia nā lymphocytes i loko o ka iwi iwi. No laila, hiki i nā maʻi koko a me nā maʻi ʻaʻai e hoʻopilikia ana i ka iwi iwi ke hoʻopilikia i ka hana ʻana o nā lymphocytes.
- ʻAʻohe anemia aplastic - kahi kūlana kahi e hoʻopuka ai ka iwi iwi i nā cell liʻiliʻi
- ʻO Lymphoma - kahi maʻi ʻaʻai o ka ʻōnaehana lymphatic
- Leukemia - he maʻi ʻaʻai koko
- Nā maʻi Myelodysplastic
6. Ma ke ʻano he hopena ʻaoʻao o nā lāʻau lapaʻau a me nā lāʻau lapaʻau
Hiki ke hoʻemi ʻia nā lymphocytes, ʻoiai ma muli o nā lāʻau lapaʻau no ka maʻi kanesa a me kekahi mau lāʻau lapaʻau no nā maʻi autoimmune.
- Hoʻoili iwi iwi
- Kemoterapia
- Hoʻōla radiation
- Nā Immunosuppressants - no ka laʻana, corticosteroids.
7. Ma muli o ka ʻona waiʻona
ʻO ka inu nui ʻana i ka waiʻona (e like me ka pia, ka waina, a me ka lama) hiki ke hoʻopilikia maikaʻi ʻole i nā lymphocytes, e hoʻemi ana i ko lākou helu.
Pehea ʻoe e ʻike ai inā loaʻa iā ʻoe ka lymphopenia?
Inā kānalua ʻoe he lymphopenia kou, ʻoi aku ka maikaʻi o ke ʻike ʻana i ke kauka a kamaʻilio e pili ana i ia mea. E nīnau ke kauka e pili ana i kou mōʻaukala olakino, nā hōʻailona o kēia manawa, a me ke ʻano o ka nohona. A laila hiki iā lākou ke hana i kekahi mau hoʻokolohua.
Ka hoʻokolokolo a me ka nīnau ʻana a ke kauka
- Mōʻaukala lapaʻau: E nīnau kāu kauka e pili ana i kāu mōʻaukala lapaʻau i hala, nā lāʻau lapaʻau o kēia manawa, a me nā lāʻau lapaʻau. No ka laʻana, inā ua loaʻa iā ʻoe ʻo COVID-19 i kēia manawa, manaʻo paha kāu kauka ua hoʻemi ʻia kāu helu lymphocyte e kahi maʻi viral. Inā ʻoe e lawe nei i nā lāʻau lapaʻau e like me corticosteroids, hiki nō hoʻi ke lilo i kumu.
- Hoʻokolohua kino: E nīnau ke kauka e pili ana i kāu mau hōʻailona a nānā i nā mea e like me ke kuni, nā kīʻaha lymph pehu, a me ka spleen i hoʻonui ʻia.
- Nā nīnau e pili ana i ke ʻano o ka nohona: E nīnau ʻia paha ʻoe e pili ana i kāu ʻai e ʻike ai inā he mau hemahema kāu i ka meaʻai. E nīnau ʻia paha ʻoe e pili ana i kou ola moekolohe (e like me ke hoʻohana ʻana i nā ʻano palekana) e kāpae i nā maʻi e like me ka HIV.
He aha nā hoʻokolohua e hana ʻia?
Aia kekahi mau hoʻokolohua e nānā ai i nā hunaola koko a me ka iwi iwi.
- Helu Koko Piha (CBC): Helu kēia i ka helu o nā ʻano ʻano koko āpau i loko o kou koko (me nā ʻano koko keʻokeʻo).
- Helu koko piha me ka ʻokoʻa (CBC me ka ʻokoʻa): Helu kēia i ka helu o kēlā me kēia ʻano keʻokeʻo koko (me nā platelets) ma ke kaʻawale.
- ʻO ka cytometry kahe: He hoʻāʻo kūikawā kēia. Hiki iā ia ke ana ʻokoʻa i nā ʻano lymphocytes, e like me nā pūnaewele B, nā pūnaewele T, a me nā pūnaewele NK.
- Hoʻāʻo pae Immunoglobulin: Ke ana kēia i ka nui o nā protein i kapa ʻia he antibodies i loko o kou koko. Hiki iā ia ke kōkua i ka ʻike ʻana i nā kūlana he nui e pili ana me ka lymphopenia, e like me nā maʻi, nā maʻi autoimmune, a me ke kanesa.
- Ka nānā ʻana i ka iwi iwi: ʻAʻole hana ʻia kēia no nā mea āpau, akā hiki i kāu kauka ke ʻōlelo i kēia hoʻāʻo inā he kānalua he pilikia koʻikoʻi me ka hana ʻana o nā lymphocytes.
Eia kekahi, hiki ke hana ʻia nā hoʻokolohua ʻē aʻe e nānā i nā maʻi kikoʻī e hoʻoulu ai i ka lymphopenia (e like me ka hoʻāʻo HIV, ka hoʻāʻo tuberculosis, ka hoʻāʻo flu, a i ʻole ka hoʻāʻo COVID-19).
He aha nā lāʻau lapaʻau no ka lymphopenia?
I ka hapanui o nā hihia , ʻaʻole pono ka lymphopenia liʻiliʻi, ʻoiai inā ʻaʻohe hōʻailona, i kekahi lāʻau kūikawā. Inā hana ʻia e kahi mea e like me ka maʻi, e hoʻi ka helu o nā lymphocytes i ka maʻamau ke hoʻōla ke kino mai ka maʻi.
ʻO ka mea nui loa, ʻo ia ka mālama ʻia ʻana o ka lymphopenia ma ka mālama ʻana i ke kumu kumu.
Ma hope o ka ʻike ʻana i ke kumu o kou mau lymphocytes haʻahaʻa, e kuhikuhi kāu kauka i ka lāʻau kūpono.
Hiki ke ho'ōla loa ʻia ka Lymphopenia?
Inā ua hānau ʻia ʻoe me kahi maʻi genetic e pale ana iā ʻoe mai ka hana pono ʻana i nā lymphocytes, hiki i kahi lāʻau i kapa ʻia he hematopoietic stem cell transplant ke lilo i mea lapaʻau i kekahi manawa. Pili kēia i ka wehe ʻana i nā cell kumu koko i hōʻino ʻia a kīnā paha a hoʻololi iā lākou me nā cell kumu olakino. A laila hana kēia mau cell hou i nā lymphocytes, a me nā cell koko ʻē aʻe.
Eia nō naʻe, he ʻano paʻakikī kēia lāʻau lapaʻau, a aia kekahi mau pilikia e pili ana. ʻAʻole hiki i nā kānaka a pau ke hana i kēia. E haʻi aku kāu kauka iā ʻoe inā kūpono kēia iā ʻoe a i ʻole.
Nā lāʻau lapaʻau i hoʻohana ʻia no ka mālama ʻana
Inā loaʻa iā ʻoe ka lymphopenia koʻikoʻi, ʻo ia hoʻi ka loaʻa pinepine ʻana o nā maʻi, hiki i kāu kauka ke hāʻawi iā ʻoe i nā pana immunoglobulin (IG) . Hoʻoikaika kēia mau pana i kou ʻōnaehana pale a kōkua iā ʻoe e hakakā i nā maʻi. Hiki ke aʻo ʻia ʻoe e hoʻomau i ka lawe ʻana i kēia mau pana IG e pale aku i nā maʻi pinepine.
Hiki ke pale ʻia ka lymphopenia?
ʻAʻole hiki ke pale ʻia ka Lymphopenia i hoʻokumu ʻia e nā kumu genetic. Eia nō naʻe, aia kekahi mau mea hiki iā ʻoe ke hana e hōʻemi i kou pilikia o ka loaʻa ʻana o ka lymphopenia mai nā kumu ʻē aʻe:
- E pale iā ʻoe iho mai nā germs: E hana i nā hana āpau e hiki ai ke pale iā ʻoe iho mai nā germs e hoʻoulu ai i nā maʻi.
- Nā hana moe kolohe palekana: E hahai i nā ʻano palekana e pale aku ai i nā maʻi i laha ma ke moe kolohe (STI) e like me ka HIV.
- Kaohi ʻana i ka waiʻona: Inā inu ʻoe i ka waiʻona, e kaupalena iā ia. ʻOi aku ka maikaʻi o ka lawe ʻole ʻana ma mua o hoʻokahi kini pia, hoʻokahi kīʻaha waina, a i ʻole hoʻokahi pana waiʻona i kēlā me kēia lā.
Inā loaʻa iā ʻoe ka lymphopenia, pehea e hiki ai iā ʻoe ke pale iā ʻoe iho mai nā maʻi?
Inā haʻahaʻa kāu helu lymphocyte, he mea nui e pale iā ʻoe iho mai nā maʻi. Eia kekahi mau mea e hiki ke kōkua:
- E kiʻi i ka lāʻau pale: E kiʻi i ka lāʻau pale no ka maʻi flū a me COVID-19. E nīnau i kāu kauka e pili ana i nā lāʻau pale ʻē aʻe.
- E pale i nā wahi i kiʻekiʻe ai ka pilikia o ka maʻi: E noho mamao aku mai ka poʻe maʻi a i ʻole ka poʻe maʻi paha. E hōʻemi i ka pili ʻana i nā wahi piha kanaka a me nā wahi i loko ʻole i hoʻokomo ʻia ai ka ea.
- E holoi pinepine i kou mau lima: E holoi pono i kou mau lima me ke kopa a me ka wai, a i ʻole e hoʻohana i kahi mea hoʻomaʻemaʻe lima i loaʻa ka waiʻona.
- E ʻaʻahu i ka pale maka: E ʻaʻahu i ka pale maka i ka wā e hele ai i nā wahi i loaʻa ai nā maʻi lele.
- Palekana meaʻai: E hoʻomoʻa pono i ka meaʻai. E holoi pono i nā huaʻai a me nā mea kanu ma mua o ka ʻai ʻana.
- E pale i nā ʻeha: ʻO nā ʻeha e like me nā ʻoki a me nā ʻōpala hiki ke hoʻokomo i nā germs i loko o ke kino, no laila e makaʻala i ia mau pōpilikia.
Eia kekahi, e nīnau i kāu kauka inā he mau mea āu e makaʻala nui ai.
He aha ke kūlana olakino o ka poʻe me ka lymphopenia? (Outlook/Prognosis)
Aia wale nō kēia ma ke kumu o kou mau lymphocytes haʻahaʻa. ʻO ka maʻamau, inā ma muli o kahi maʻi ka emi ʻana, e hoʻi ka helu lymphocyte i ka maʻamau ke hoʻōla ʻia ka maʻi. Eia nō naʻe, inā ma muli o kahi kumu koʻikoʻi, hiki ke lōʻihi iki a paʻakikī ke kaʻina hana lapaʻau.
He aha nā manawa kūpono loa e ʻike ai i ke kauka?
Inā loaʻa iā ʻoe kekahi mau hōʻailona o ka maʻi (e like me ke kuni, ke kuni, ka ʻeha o ke kino), e ʻike koke i ke kauka. Inā loaʻa iā ʻoe kahi maʻi e hoʻoweliweli iā ʻoe no nā maʻi pinepine (e like me ka lymphopenia), e nīnau mua i kāu kauka i nā hōʻailona āu e ʻimi ai i ka ʻōlelo aʻoaʻo lapaʻau.
He maʻi ʻaʻai anei ka lymphopenia?
ʻAʻole, ʻaʻole ka lymphopenia he maʻi kanesa. Eia nō naʻe, hiki i kekahi mau ʻano maʻi kanesa (e like me ka leukemia, lymphoma) ke hoʻopilikia i ka hana ʻana o nā lymphocytes, e hana ana i ka lymphopenia. Eia kekahi, hiki i kekahi mau lāʻau lapaʻau maʻi kanesa (e like me ka chemotherapy) ke hoʻohaʻahaʻa i ka pae o nā lymphocytes no kekahi manawa.
Leka Lawe-Home
ʻAe, i kēia manawa ua ʻoi aku kou maopopo i ka mea a mākou i kamaʻilio ai i kēia lā, ʻo Lymphopenia. E hoʻomanaʻo:
- ʻO ka Lymphopenia ka emi ʻana o ka helu o nā lymphocytes, kahi ʻano cell e hakakā ana i nā maʻi i loko o ke koko.
- ʻAʻole kēia he mea ʻē aʻe, pili pinepine ia i kahi maʻi, ka hemahema o nā meaʻai, ka hopena ʻaoʻao o ka lāʻau lapaʻau, a i ʻole kekahi maʻi ʻē aʻe.
- I ka hapanui o nā hihia, ʻaʻole hōʻike nā hihia maʻalahi i nā hōʻailona.
- Inā maʻi pinepine ʻoe, a kānalua paha no kēia, ʻo ka mea maikaʻi loa e hana ai, ʻo ia ke ʻike i ke kauka a noi i ka ʻōlelo aʻo.
- Inā loaʻa ke kumu a mālama pono ʻia, hiki ke kaohi pinepine ʻia kēia ʻano.
No laila, e mālama i kou olakino. Mai makaʻu e kamaʻilio me kāu kauka inā he mau nīnau kāu. E noho olakino!
ʻLymphopenia , nā pūnaewele lymph, nā lymphocytes, nā pūnaewele koko keʻokeʻo, ka palekana, nā maʻi, nā hōʻailona
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