Ua noʻonoʻo paha ʻoe pehea e ulu ai ka ʻōpū, nā ʻōpū fallopian, a me ka cervix, nā ʻōpū kūikawā i nā wahine, i nā wā mua loa o ke ola o kahi pēpē? He hana kupaianaha a paʻakikī maoli nō ia. Hoʻomaka ia me ʻelua mau ʻōmole liʻiliʻi a palupalu loa e hana ʻia i ka wā o ka embryonic. I ka lāʻau lapaʻau, kapa mākou i kēia mau mea ʻo 'Müllerian ducts'. ʻAʻole paha ʻoe i lohe i kēia inoa ma mua. Akā i ka wā e pili ana i ke olakino hānau o ka wahine, he mea nui e ʻike e pili ana i kēia ʻōnaehana o nā ʻōmole. No laila i kēia lā, e kamaʻilio kākou e pili ana iā ia me ka maʻalahi a ma ke ʻano hiki iā ʻoe ke hoʻomaopopo.
I ka ʻōlelo maʻalahi, he aha kēia mau Müllerian Ducts?
ʻO nā ducts Müllerian ʻelua mau paipu i hui pū ʻia e hana ʻia i loko o kahi fetus i kona ulu ʻana i loko o ka ʻōpū o ka makuahine. Ua kapa ʻia kēia mau ducts he paramesonephric ducts. Eia nō naʻe, ʻo ka inoa ʻo Müllerian ducts ka mea i hoʻohana pinepine ʻia.
ʻO kā lākou hana nui ka hana ʻana i nā ʻōkana nui o ka ʻōnaehana hānau o ka wahine. ʻO kēia mau ʻōpuʻu ʻelua ka mea e ulu aʻe ma hope i kēia mau ʻōkana:
- ʻUterus: ʻO ke kino kupaianaha e hāpai a hānai i kahi pēpē no ʻeiwa mahina.
- Nā paipu Fallopian: ʻO nā paipu ʻelua e lawe ana i kahi hua manu mai nā ovaries a i ka uterus.
- Cervix: ʻO ka ʻāpana haʻahaʻa o ka ʻōpū e pili ana i ka vagina.
- ʻĀpana o luna o ka vagina.
E noʻonoʻo wale, ʻo kēia mau ʻōmole liʻiliʻi ʻelua ka mea e ulu a lilo i mau ʻōkana koʻikoʻi e pono ai e lilo i makuahine a hānau i keiki i ka wā e hiki mai ana.
ʻO ka mea kupaianaha, aia kēia mau ala Müllerian i loko o nā embryos āpau, me ka nānā ʻole i ke kāne, i nā pae mua o ka ulu ʻana. No laila pehea lā i loaʻa ʻole ai i kahi pēpē kāne kahi uterus, akā he pēpē wahine wale nō?
ʻO ke kumu o kēia, ʻo ia ka hoʻokaʻawale ʻana o ke kino, ke kaʻina hana e ulu ai nā ʻōpū moe. I loko o kahi fetus kāne, ua hoʻokuʻu ʻia kahi hormone kūikawā i kapa ʻia ʻo ka hormone anti-Müllerian (AMH) . Hoʻōki kēia hormone i ka ulu ʻana o nā ducts Müllerian a hoʻopau mālie iā lākou. ʻO ka hopena, ʻaʻole ulu nā ʻōpū e like me ka uterus i kahi fetus kāne.
Eia nō naʻe, i loko o kahi ʻōpū wahine, ʻaʻole i loaʻa kēia hormone AMH. No laila, ulu nā ala Müllerian me ke keakea ʻole, a hoʻokumu ʻia nā ʻōpū hānau wahine i ʻōlelo ʻia ma mua.
No laila he aha nā Wolffian Ducts? He aha ka ʻokoʻa ma waena o nā mea ʻelua?
Me nā ducts Müllerian, ʻo kekahi ʻōnaehana o nā ducts i loaʻa i kēlā me kēia embryo mua ʻo ia nā ducts Wolffian. Ua kapa ʻia kēia mau mea he mesonephric ducts. He ʻokoʻa loa nā hana o kēia mau ducts ʻelua mai kekahi i kekahi. No ka hoʻomaopopo pono ʻana i kēia, e nānā i ka papa ma lalo.
| ʻAno | Nā ʻAuwai Müllerian | Nā ʻAuwai Wolffian |
|---|---|---|
| Hana nui | Ka ulu ʻana i loko o nā ʻāpana o ka ʻōnaehana hānau wahine. | Ka ulu ʻana i loko o nā ʻōpū o ka ʻōnaehana hānau kāne. |
| I loko o kahi fetus wahine | Hoʻomohala maikaʻi ia a hana i ka uterus, nā ʻōpū fallopian, a me nā mea ʻē aʻe. | E palaho mālie ana, e waiho ana i nā ʻāpana liʻiliʻi ʻole. |
| I loko o kahi fetus kāne | ʻO ka Anti-Müllerian Hormone (AMH) ke kumu o ka hoʻōki ʻana o ka ulu ʻana a me ka atrophy. | Ulu maikaʻi ia ma lalo o ka mana o ka hormone testosterone. |
| Nā kino e ulu a hoʻokumu | ʻUterus, nā ʻōpū fallopian, ka cervix, ka ʻāpana o luna o ka vagina. | ʻO nā ʻōpū momona, nā epididymis, a me nā vesicle seminal. |
I ka ʻōlelo maʻalahi, ʻoiai aia kēia mau ʻōnaehana vascular ʻelua i loko o ka embryo hoʻokahi, ma lalo o ka mana o nā hormones, ulu kekahi aʻo kekahi e mae. ʻO kēia ke kaulike kupaianaha o ke kūlohelohe.
Pehea e ulu ai kēia mau ʻōpuʻu a ma hea lākou e loaʻa ai?
Hoʻomaka kēia kaʻina hana i ka wā mua loa o ka hāpai ʻana. Hāpai ʻia kahi pēpē i loko o ka ʻōpū 3-4 mau pule ma hope o ka hānau ʻana.Hoʻomaka kēia moʻolelo a puni ka manawa o ka hāpai ʻana. I kēlā manawa, hoʻomaka kēia mau ala Müllerian e ulu ma kahi kokoke i nā puʻupaʻa mua (nā puʻupaʻa mesonephric) i loko o ka embryo. He manawa pōkole kēia mau puʻupaʻa mua, a ulu nā puʻupaʻa mau loa ma hope.
Ulu kēia mau ducts i lalo e like me nā ʻōpuʻu lōʻihi e like me ka manamana lima. Ma waena o 8 a me 12 mau pule o ka hāpai ʻana, hui pū nā wēlau o nā ducts Müllerian ʻelua e iho ana. ʻO kēia hui ʻana ke kumu no nā ʻōpū e like me ka uterus a me ka vagina. Hana ʻia kēia mau ducts i ʻelua ʻano cell kūikawā.
- Nā pūnaewele Epithelial: Ua like kēia me kahi uhi pale no ko mākou mau kino a kōkua pū kekahi i ka omo ʻana a me ka hūnā ʻana i nā mea nui.
- Nā pūnaewele Mesenchymal: He ʻano kēia o nā pūnaewele kumu. ʻO ia hoʻi, hiki i kēia mau pūnaewele ke ulu i nā ʻano pūnaewele like ʻole e like me ka mea e pono ai.
Hiki ke hana i nā anomalies o ke kahawai Müllerian?
ʻAe, i kekahi manawa ʻaʻole ulu pono kēia mau ala Müllerian a ʻaʻole hoʻi e pili pū kekahi, e hopena ana i nā kīnā a me nā ʻano ʻē. He mau maʻi hānau pinepine kēia.
ʻO ka mea nui, ʻaʻole paha ʻoe e ʻike he maʻi kou a hiki i kou wā makua a male paha a ke manaʻo nei i kahi keiki. No ka mea, ʻaʻohe paha he mau hōʻailona o waho. ʻIke wale kekahi mau wahine he maʻi ko lākou ke ʻimi nei lākou i nā kumu o ka hānau ʻole ʻana.
Aia ma ka papa ma lalo nei kekahi o nā hemahema o ka ʻauwai Müllerian maʻamau.
| Ka inoa o ka ʻano ʻē | He aha kēia e hana nei? |
|---|---|
| ʻO ka agenesis Müllerian a i ʻole hypoplasia | ʻAʻole i loaʻa ka ʻōpū mai ka wā hānau (agenesis) a i ʻole he liʻiliʻi loa a ulu ʻole (hypoplasia) . ʻO ka laʻana maʻamau o kēia, ʻo ia ke ʻano genetic Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome . |
| ʻO ka septum vaginal | Inā ʻaʻole e hui pono nā ʻōmole ʻelua i ka wā e hui ai lākou ma lalo, e hana ʻia kahi membrane ma waena o ka vagina. Hiki i kēia ke hana i ka vagina e ālai hapa a piha paha, a i ʻole hiki ke hana ʻia ʻelua vagina. |
| ʻO ka maʻi duct Müllerian mau loa (PMDS) | He maʻi hoʻoilina laha ʻole kēia e hoʻopilikia ana i nā keikikāne. Ma muli o ka hana pono ʻole o ka hormone AMH, ulu pū kahi ʻōpū a me nā ʻōpū fallopian me nā ʻōpū hānau kāne maʻamau. Loaʻa paha i kēia mau kāne nā pilikia e like me nā testicles i iho ʻole i lalo. |
| Nā ʻano ʻino o ka ʻōpū | Hiki i nā pilikia me ka ulu ʻana o ka tubal ke hoʻololi i ke ʻano o ka uterus. ʻO nā hiʻohiʻona e komo pū me ka uterus bicornuate, ka uterus didelphys, ka uterus septate, a me ka uterus ʻano T. |
Hiki i kekahi poʻe me kēia mau kīnā ke loaʻa nā pilikia me ko lākou mau puʻupaʻa. ʻO kēia no ka mea e ulu kokoke ana kēia mau ʻōkana ʻelua i ka wā o ka fetal, a hiki i kahi kīnā i kekahi ke hoʻopilikia i kekahi.
He mea maʻamau anei kēia ʻano hewa?
ʻAʻole. ʻAʻole pono ʻoe e hopohopo no kēia. He mau maʻi kakaikahi loa kēia. Wahi a nā helu helu, loaʻa kēia ʻano kīnā i kahi pakeneka liʻiliʻi loa o nā hānau ola, ma waena o 0.1% a me 3.0% . ʻO ke ʻano kēia, ua haʻahaʻa loa ka manawa e hana ai kekahi mea e like me kēia.
He aha nā nīnau āu e nīnau ai i ke kauka?
Inā ʻike ke kauka iā ʻoe a i ʻole kāu keiki me kahi kīnā o ke alapiʻi Müllerian, he mea maʻamau ka loaʻa ʻana o nā nīnau he nui i loko o kou manaʻo. I kēlā manawa, me ka ʻole o ka hūnā ʻana i kekahi mea, e nīnau i kāu kauka i kēia mau nīnau.
- E hoʻopilikia anei kēia maʻi i koʻu hiki ke hānau keiki?
- E hoʻopilikia anei kēia i kaʻu mau hormones?
- He aha nā lāʻau lapaʻau no kēia? Pono anei ke ʻoki kino?
- E hana maʻamau anei koʻu wā ʻōpio a me koʻu menstruation?
E hāʻawi kāu kauka i nā pane maopopo i kēia mau nīnau a pau a hāʻawi iā ʻoe i ke alakaʻi āu e pono ai.
Hiki ke pale ʻia kēia ʻano hewa i ka wā hāpai?
He pilikia kēia i loaʻa i nā poʻe he nui. ʻO kaʻoiaʻiʻo, ʻaʻohe ala e pale loa ai i nā hemahema o ka ʻauwai Müllerian.No ka mea, ua hana pinepine ʻia kēia mau mea e nā kumu genetic a i ʻole kahi hewa kaulele i ka wā o ka ulu ʻana o ka fetal.
Akā, ʻaʻole ia manaʻo ʻaʻohe mea hiki iā mākou ke hana. Ma ke ʻano he makuahine hāpai, hiki iā ʻoe ke hahai i kahi nohona olakino e hōʻemi i kou pilikia o nā kīnā hānau ma ke ʻano laulā. He mea nui kēia ʻaʻole wale no kēia ʻano kīnā, akā no ke olakino holoʻokoʻa o kāu pēpē.
- E hōʻalo loa i nā lāʻau lapaʻau kū ʻole i ke kānāwai a me ka mariuana.
- E pale loa i ka puhipaka a me ka waiʻona. He mea ʻino loa kēia i ka ʻōpū.
- E hōʻoia e loaʻa iā ʻoe ka ʻōlelo aʻoaʻo lapaʻau kūpono a me ka mālama prenatal i ka wā hāpai.
- Inā loaʻa iā ʻoe nā maʻi mau e like me ka maʻi diabetes a i ʻole ke koko kiʻekiʻe, e kaohi pono iā lākou ma mua o ka hāpai ʻana.
- E lawe i nā huaora prenatal i loaʻa ka folic acid e like me ka ʻōlelo a kāu kauka.
- E mālama i ke kaumaha olakino.
- E ʻai i ka meaʻai kaulike a e hoʻoikaika kino i kēlā me kēia lā.
Me kēia mau mea maʻalahi, hiki iā ʻoe ke hana i ke kaiapuni maikaʻi loa no kāu pēpē i hānau ʻole ʻia e ulu olakino.
Leka Lawe-Home
- ʻO nā ducts Müllerian kahi ʻōnaehana o nā ducts i hana ʻia i ka wā embryonic a he mea nui ia i ka ulu ʻana o nā ʻōpū hānau o ka wahine, e like me ka uterus a me nā fallopian tubes.
- Loaʻa kēia mau kīnā ulu i ka wā hānau a ʻaʻole hiki ke ʻike ʻia a hiki i ka wā makua a i ʻole i ka wā e manaʻo ʻia ai nā keiki.
- He mea kākaʻikahi loa kēia mau hemahema, a he nui nā ʻano lapaʻau a me nā ʻano hoʻokele no ka hapa nui o lākou.
- Inā he mau hopohopo a kānalua paha kāu e pili ana i kēia, he mea nui loa e kamaʻilio ākea me kāu kauka e pili ana i ia mea a loaʻa iā ʻoe ka ʻōlelo aʻoaʻo kūpono.
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