ʻO ka ʻōnaehana huna o nā aʻa liʻiliʻi i loko o ka puʻupaʻa: E aʻo wale kākou e pili ana i nā Capillaries Peritubular

Ua ʻike mākou a pau ʻo nā puʻupaʻa nā kānana i loko o ko mākou kino. E like me ke kānana ʻaila i loko o ke kaʻa, hana maikaʻi kēia mau puʻupaʻa ʻelua i ka hoʻomaʻemaʻe ʻana i ko mākou koko a me ka wehe ʻana i nā huahana ʻōpala pono ʻole e like me ka mimi. Akā ua lohe anei ʻoe e pili ana i nā koa liʻiliʻi ma hope o kēia hana nui, nā mea āu e ʻike ʻole ai? ʻO kēlā mau koa ka mea a mākou e kapa nei he 'Peritubular Capillaries'. ʻOiai paha he paʻakikī iki ka inoa, he maʻalahi loa a he mea nui ka hana a lākou e hana ai. I kēia lā, e kamaʻilio kākou e pili ana i kēia ʻōnaehana liʻiliʻi o nā aʻa koko.

I ka ʻōlelo maʻalahi, he aha kēia mau capillaries peritubular?

ʻAe, e wehewehe kākou i kēia inoa.

• ʻO ke ʻano o Peri ʻo ia hoʻi "a puni".
• ʻO ke ʻano o ka huaʻōlelo Tubular he "nā kahawai liʻiliʻi".
• ʻO nā capillaries nā kīʻaha koko maikaʻi loa i loko o ko mākou kino.

No laila, i ka ʻōlelo maʻalahi, ʻo nā capillaries peritubular he pūnaewele o nā kīʻaha koko maikaʻi loa e hoʻopuni ana i nā kahawai liʻiliʻi i loko o ko kākou mau puʻupaʻa. E noʻonoʻo he kūlanakauhale nui ka puʻupaʻa. Aia ma kahi o hoʻokahi miliona mau hale liʻiliʻi ma ia kūlanakauhale. Kāhea mākou i kēia mau hale he nephrons . ʻO kēia mau nephrons nā ʻāpana e kānana a hoʻomaʻemaʻe i ke koko. No laila, ʻo ka pūnaewele o nā ala liʻiliʻi e hoʻopuni ana i kēlā me kēia o kēia mau hale (a puni nā kahawai nephron) ua kapa ʻia ʻo nā capillaries peritubular. Ma o kēia mau ala e lawe ʻia mai ai nā waiwai e pono ai (meaʻai) i nā hale a lawe ʻia aku nā ʻōpala (ʻōpala) e hōʻiliʻili ana i loko o nā hale.

He aha nā mea nui ʻelua e hana ʻia ana ma kēia ʻōnaehana aʻa koko liʻiliʻi?

Ua like kēia pūnaewele o nā kīʻaha koko liʻiliʻi me kahi mea helu akamai. Koho pono ia a hoʻokaʻawale i nā mea e pono ai ke kino a me nā mea ʻaʻole. Hiki ke hoʻokaʻawale ʻia kēia hana i ʻelua ʻāpana nui.

1. Hoʻokuʻu ʻia: Ma hope o ke kaʻina kānana mua i loko o nā puʻupaʻa, hoʻokuʻu ʻia nā huahana ʻōpala i koe i loko o ke koko mai kēia mau aa koko i loko o nā tubules renal. A laila hoʻokuʻu ʻia kēia mau huahana ʻōpala i loko o ka mimi.

2. Ka hoʻopili hou ʻana i nā meaʻai: Ke kānana nā puʻupaʻa i ke koko, i kekahi manawa ua kānana ʻia kekahi o nā mea maikaʻi e pono ai ke kino. E noʻonoʻo e like me ke kānana ʻana i kahi kīʻaha kī, ua paʻa kekahi kō i loko o ke kānana me nā lau kī. I kēlā mau manawa, ʻike kēia mau capillaries peritubular i kēlā mau meaʻai a hoʻopili hou iā lākou i loko o ke koko.

E nānā kākou i kēia papa e ʻike ai i ke koʻikoʻi o kēia mau kaʻina hana ʻelua.

He aha ka mea e hana ʻia inā ua hōʻino ʻia kēia mau capillaries?

ʻO kēia kahi e pono ai mākou e hopohopo nui. Ke hoʻomaka kēia mau kīʻaha koko palupalu e hōʻino ʻia, ʻaʻole hiki iā lākou ke hana pono i kā lākou hana. Kāhea mākou i kēia kūlana he peritubular capillary rarefaction . ʻO ke ʻano kēia e emi ana ka nui o kēia mau kīʻaha koko, e lahilahi lākou, a ua luku ʻia lākou.

ʻO ka mea weliweli loa e pili ana i kēia, ʻo ia ka wā e hōʻino ʻia ai kēia mau kahawai, ua liʻiliʻi loa ko lākou manawa e hoʻōla ai.

Hiki i kēia pōʻino ke alakaʻi i ʻelua mau maʻi olakino nui:

1. Maʻi Puʻupaʻa Mau Loa (CKD):Ke hāʻule nā ​​​​capillaries, e hoʻopilikia mālie ʻia ke kaʻina kānana o nā puʻupaʻa. I ka hala ʻana o ka manawa, hiki i kēia ke holomua i ka maʻi puʻupaʻa mau loa, a i ka hopena e alakaʻi ai i ka hāʻule ʻana o nā puʻupaʻa.

2. Hypertension: Hoʻomalu nā puʻupaʻa i ka nui o ka paʻakai a me ka wai i loko o ke kino. Ke hōʻino ʻia kēia mau capillaries, nalowale kēia kaohi. ʻO ka hopena, hoʻomaka ke koko e piʻi. Eia kekahi, hoʻopōʻino hou ke koko kiʻekiʻe i kēia mau capillaries. Ua like ia me kahi pōʻaiapuni ʻino.

He aha nā kumu kūpono e hōʻino ai i kēia mau capillaries?

• Maʻi diabetes
• Ke koko kiʻekiʻe i kāohi ʻole ʻia
• nā maʻi puʻupaʻa
• Nā maʻi glomerular (nā maʻi e hoʻopilikia ana i nā ʻāpana kānana o nā puʻupaʻa)
• Ka pale ʻana o ka ureter

He aha nā hōʻailona e hōʻike ana i kahi pilikia o ka puʻupaʻa?

ʻAʻole hōʻike pinepine ka maʻi puʻupaʻa i kekahi mau hōʻailona nui i nā pae mua. Akā inā ʻoe e nānā pono i kou kino, hiki iā ʻoe ke ʻike i kekahi o nā hōʻailona. Inā loaʻa iā ʻoe kekahi a ʻoi aku paha o kēia mau hōʻailona, ​​​​he mea nui e ʻimi koke i ke kōkua lapaʻau .

• ʻEha ma nā ʻaoʻao ʻelua o ke kino, ma lalo o nā iwi ʻaoʻao.
• Ke kuni e hiki mai ana me ke kumu ʻole.
• Ka luaʻi a me ka luaʻi.
• Ka luhi nui o ke kino.
• Nā loli i ke ʻano o ka mimi ʻana:
• ʻOi aku ka pinepine o ka mimi ʻana ma mua o ka maʻamau.
• Paʻakikī i ka mimi ʻana.
• Ke koko i loko o ka mimi (hematuria) .
• ʻEha a wela paha i ka wā e mimi ai (dysuria) .
• Ka loli ʻana o ke kala o ka mimi (lilo i ʻeleʻele).
• ʻO ka pehu ʻana (edema), ʻoi aku hoʻi ma nā wāwae, ka ʻāpana kuʻekuʻe wāwae.
• Nā maʻi ʻōpū mimi hou (UTIs).

Inā loaʻa iā ʻoe kēia mau hōʻailona, ​​​​mai kali wale a manaʻolana, "E maikaʻi kēia i loko o kekahi mau lā." E hōʻoia e ʻike i kāu kauka a hana i nā hoʻokolohua e pono ai.

He aha nā hoʻokolohua e nānā ai i ke olakino o nā puʻupaʻa?

Ma muli o kāu mau hōʻailona, ​​​​hiki i kāu kauka ke kuhikuhi i kekahi mau hoʻokolohua e like me kēia.

1. Nā Hoʻāʻo Hana o nā Pūpū:

• Urinalysis: Nānā ʻia ka mimi no nā mea e like me ka protein, ke koko, a me ke kō.
• Nā hoʻāʻo koko:Hoʻopaʻa ʻia nā pae o nā huahana ʻōpala i kapa ʻia ʻo `BUN (Blood Urea Nitrogen)` a me `Creatinine` i loko o ke koko. Inā kiʻekiʻe kēia mau mea, ʻo ia hoʻi ʻaʻole e kānana pono nā puʻupaʻa i nā huahana ʻōpala. Hiki i kahi hoʻāʻo i kapa ʻia ʻo `eGFR (estimated Glomerular Filtration Rate)` ke hāʻawi i kahi manaʻo maikaʻi o ka helu kānana o nā puʻupaʻa.

2. Nā Hoʻāʻo Kiʻi:

• ʻO ke Kidney Ultrasound: Hiki i kēia ke nānā i ka nui, ke ʻano, a me ke alo o nā pōhaku a i ʻole nā ​​​​mea pale ʻē aʻe i loko o nā puʻupaʻa.
• CT Scan a i ʻole MRI Scan: Hoʻohana ʻia kēia mau mea inā pono ʻoe e nānā pono i nā puʻupaʻa.

Pehea mākou e pale ai i kēia ʻōnaehana capillary makamae?

ʻAʻohe mea kūikawā hiki iā ʻoe ke hana no kēia mau capillaries peritubular. ʻO ka mea wale nō e pono ai mākou e hana, ʻo ia ke mālama i ko mākou mau puʻupaʻa i ke olakino. Inā olakino nā puʻupaʻa, olakino pū kēia ʻōnaehana vascular liʻiliʻi. E hoʻolilo i kēia mau mea maʻalahi i mea maʻamau.

• E inu i ka wai maʻemaʻe i ka lā a pau. ʻO ka inu ʻana i ka wai e maʻalahi ai i nā puʻupaʻa ke kānana a wehe i nā mea ʻōpala.
• E ʻai i ka ʻai kaulike. E hōʻemi i nā meaʻai kiʻekiʻe i ka paʻakai, ke kō, a me ka momona i ka hiki. E ʻai i nā huaʻai a me nā mea kanu hou aku.
• E kāohi i ka maʻi diabetes a me ke koko kiʻekiʻe. Inā loaʻa iā ʻoe kēia mau maʻi, e lawe i ka lāʻau lapaʻau a kāu kauka i kuhikuhi ai i ka manawa kūpono. E nānā mau ʻia.
• E mālama i ke kaumaha olakino no kou kino. ʻO ke kaumaha nui e kau i ke kaumaha hou aʻe ma luna o nā puʻupaʻa.
• E pale loa i ka puhipaka. ʻO ka puhipaka kekahi kumu nui o ka hōʻino ʻana i nā kīʻaha koko. Hoʻopilikia pololei kēia i nā capillaries peritubular.
• Mai hoʻomau i ka hoʻohana ʻana i nā lāʻau lapaʻau e like me nā lāʻau ʻeha me ka ʻole o ke aʻo ʻana a ke kauka. ʻO ka hoʻohana lōʻihi ʻana i kekahi mau lāʻau ʻeha he mea hōʻino ia i nā puʻupaʻa. E kamaʻilio me kāu kauka ma mua o ka hoʻohana ʻana i kekahi lāʻau.