Ua kuhikuhi ʻia anei ʻoe a i ʻole kekahi āu i ʻike ai i ka lāʻau lapaʻau e ke kauka no kahi maʻi e like me ke kaumaha? Inā pēlā, ua lohe paha ʻoe i ka inoa ʻo SNRI. He mea maʻamau ka nui o nā nīnau e hiki mai ana i ka noʻonoʻo ke lohe ʻoe i kēia inoa. "He aha nā SNRI? Pehea lākou e hana maoli ai? Aia kekahi mau hopena ʻaoʻao?" Loaʻa paha iā ʻoe nā nīnau e like me kēia. Mai hopohopo, ʻae, a laila, e kamaʻilio kākou e pili ana i kēia mau mea a pau ma ke ʻano maʻalahi a aloha hoʻi i kēia lā.
E nānā mua kākou, he aha kēia mau SNRI?
I ka ʻōlelo maʻalahi, ʻo SNRIs (Serotonin a me Norepinephrine Reuptake Inhibitors) he papa lāʻau lapaʻau i hoʻohana ʻia e kāohi i nā hōʻailona o nā kūlana olakino noʻonoʻo e like me ke kaumaha. Eia nō naʻe, kuhikuhi nā kauka i kēia lāʻau lapaʻau no nā kūlana ʻē aʻe he nui, ʻaʻole wale ke kaumaha.
Ma Sri Lanka, ua kuhikuhi ʻia kekahi mau lāʻau lapaʻau e pili ana i kēia māhele e nā kauka. No ka laʻana, hāʻule nā lāʻau lapaʻau e like me Venlafaxine, Duloxetine, a me Desvenlafaxine i loko o kēia māhele. Eia naʻe , hiki i kāu kauka ke hoʻoholo i ka lāʻau lapaʻau kūpono iā ʻoe a me ke ʻano o ka lāʻau.
Pehea e hana ai kēia lāʻau lapaʻau i loko o ke kino?
I mea e hoʻomaopopo ai i kēia, pono mua kākou e ʻike iki e pili ana i ko kākou lolo. Loaʻa i ko kākou lolo nā ʻelele kemika kūikawā i kapa ʻia he neurotransmitters , e like me nā mea lawe leka e lawe ana i nā leka ma waena o nā ʻāpana like ʻole o ko kākou kino.
I waena o kēia mau mea , ʻo Serotonin a me Norepinephrine ʻelua o nā ʻelele nui e kaohi ana i nā mea nui he nui, e like me ko mākou ʻano, hiamoe, hoʻomanaʻo, a me ka nānā ʻana.
I nā kūlana e like me ke kaumaha, emi iho ka hana a kēia mau ʻelele. ʻO ia hoʻi, ua hoʻihoʻi koke ʻia lākou i loko o nā hunaola nerve ma hope o ka hāʻawi ʻana i ka leka (ua kapa ʻia kēia he reuptake). A laila emi iho ko lākou hopena ma ka lolo.
Hana nā SNRI ma ke kāohi ʻana i ka reuptake o ka serotonin a me ka norepinephrine. ʻO ke ʻano kēia e noho mau ana kēia mau ʻelele ʻelua i loko o ka lolo no ka manawa lōʻihi. ʻO ka hopena, hoʻomaikaʻi ko mākou ʻano a hoʻomaka mālie nā hōʻailona o ke kaumaha e emi.
No laila he aha ka ʻokoʻa ma waena o SSRI a me SNRI?
Ua lohe paha ʻoe e pili ana i nā SSRI. Hoʻopili wale nā SSRI (Selective Serotonin Reuptake Inhibitors) i ka neurotransmitter serotonin, ʻoiai ʻo SNRI e hoʻopilikia i ka serotonin a me ka norepinephrine.
ʻAʻole kēia manaʻo he "ʻoi aku ka maikaʻi" o nā SNRI ma mua o nā SSRI. Manaʻo paha kekahi poʻe he ʻoi aku ka maikaʻi o nā SSRI, aʻo kekahi poʻe e ʻoi aku ka maikaʻi o nā SNRI. Na kāu kauka e hoʻoholo i ka mea maikaʻi loa iā ʻoe ma muli o kou kūlana, nā hōʻailona, a pehea e pane ai kou kino iā lākou.
He aha nā maʻi e hoʻohana ʻia ai nā lāʻau SNRI?
Hoʻohana ʻia kēia ʻano lāʻau lapaʻau e mālama i nā ʻano maʻi like ʻole. E nānā kākou i ko lākou ʻano.
| Kūlana olakino | He wehewehe maʻalahi |
|---|---|
| Ka maʻi kaumaha nui | Ke kaumaha lōʻihi a me ka nalowale o ka hoihoi e hoʻopilikia ai i nā hana o kēlā me kēia lā. |
| Ka maʻi hopohopo laulā (GAD) | Ke hopohopo nei i ka hopohopo nui e pili ana i nā mea o kēlā me kēia lā me ke kumu ʻole. |
| ʻO ka Fibromyalgia | ʻEha mau loa ma ke kino holoʻokoʻa, luhi, a me nā pilikia hiamoe. |
| ʻO ka Neuropathy Diabetic | ʻEha, e like me ka mumū a me ka mae ʻana, i hoʻokumu ʻia e ka hōʻino ʻana o nā aʻalolo ma muli o ka maʻi diabetes. |
| ʻEha Musculoskeletal Mau Loa | Nā ʻeha lōʻihi, e like me ke kua. |
| Ka maʻi hopohopo pili kanaka | Ka makaʻu nui a me ka hopohopo i nā kūlana pilikanaka. |
Eia kekahi, ma muli o ka ʻike o ke kauka a me ka hoʻoholo lapaʻau, hiki ke ʻōlelo ʻia kēia lāʻau lapaʻau no nā hou pō e pili ana i ka menopause, ka pale ʻana i ka migraine, a me nā kūlana hopohopo ʻē aʻe.
He aha nā hopena ʻaoʻao maʻamau o kēia mau lāʻau lapaʻau?
E like me nā lāʻau lapaʻau āpau, hiki i nā SNRI ke hoʻoulu i kekahi poʻe e ʻike i nā hopena ʻaoʻao liʻiliʻi. Eia nō naʻe, he manawa pōkole kēia mau mea. E emi ana ka hapa nui o kēia mau mea i loko o nā pule mua i ka wā e hoʻomaʻamaʻa ai kou kino i ka lāʻau lapaʻau.
- Ka luaʻi a me ka luaʻi
- Waha maloʻo
- Ka paʻa ʻana o ka ʻōpū
- Luhi a me ka hiamoe
- Pōʻino
- Ka hou nui ʻana
- Nā pilikia me ka hana moekolohe (e like me ka emi ʻana o ka makemake)
ʻO ka mea nui loa, inā pilikia ʻoe i kēia mau hopena ʻaoʻao, mai hoʻowahāwahā iā lākou a kamaʻilio me kāu kauka. Hiki paha iā ia ke hoʻololi i kāu dosage a kuhikuhi paha i kahi lāʻau lapaʻau ʻē aʻe.
Nā kūlana weliweli e pono ai ka nānā kūikawā
ʻOiai he lāʻau lapaʻau maikaʻi loa nā SNRI, aia kekahi mau kūlana kakaikahi akā hiki ke pilikia e pono ai mākou e makaʻala.
1. Hoʻonui ʻia ka pilikia o nā manaʻo pepehi kanaka
Ua hōʻike ʻia nā noiʻi e piʻi aʻe ana paha nā manaʻo pepehi kanaka, ʻoiai hoʻi i nā poʻe ʻōpio ma lalo o 25 mau makahiki, i ka wā e hoʻomaka mua ʻia ai kēia lāʻau lapaʻau a i ʻole ke hoʻololi ʻia ka nui o ka lāʻau. Inā loaʻa iā ʻoe a i ʻole kāu keiki kēlā mau manaʻo i ka wā e lawe ana i kēia lāʻau lapaʻau, mai kānalua e hoʻokaʻaʻike koke aku i kāu kauka.
2. Ka maʻi Serotonin
He kūlana kakaikahi loa kēia, akā he mea hoʻoweliweli paha i ke ola. Hana ʻia ia ke kiʻekiʻe loa nā pae serotonin o ke kino. Kiʻekiʻe loa kēia pilikia ke lawe ʻia nā SNRI me nā lāʻau lapaʻau ʻē aʻe e hoʻonui ai i nā pae serotonin (e like me MAOI). No laila, he mea nui loa ia e hoʻomaopopo i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei, ʻoiai nā huaora.
| Nā Hōʻailona o ka Serotonin Syndrome | |
|---|---|
| Nā ʻano laulā | Hoʻomaha ʻole, luaʻi, kahe ʻana o ka waimaka, nā maka i hoʻonui ʻia , nā haʻalulu o nā ʻiʻo, ka hou ʻana, a me ke anu. |
| Nā hiʻohiʻona weliweli | Huikau, tachycardia, koko kiʻekiʻe, kuni nui, hopu, ʻike ʻole. |
| Inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona weliweli, e hele koke i ka haukapila Emergency Department (ETU) kokoke loa! | |
3. Ke hoʻōki koke nei i ka lāʻau lapaʻau
Inā ʻoe e hoʻōki i ka lawe ʻana i kahi SNRI no nā pule he 6 a ʻoi, hiki iā ʻoe ke ʻike i kekahi mau hōʻailona maikaʻi ʻole. Ua kapa ʻia kēia ʻo Antidepressant Discontinuation Syndrome. ʻAʻole kēia he "ʻona lāʻau." ʻO kēia wale nō ka hoʻāʻo ʻana o ke kino e hoʻomaʻamaʻa i ka lāʻau lapaʻau ke hoʻōki koke ʻia. Hiki i nā hōʻailona ke komo pū me ke kuni e like me ke kino, ka ʻeha poʻo, ka nausea, ka dizziness, a me ka manaʻo buzzing.
No laila , mai ho'ōki koke i ka lawe ʻana i kēia lāʻau lapaʻau me ka ʻole o ke kūkākūkā ʻana me kāu kauka. Inā pono ʻoe e ho'ōki i ka lawe ʻana i ka lāʻau lapaʻau, e hana pēlā e like me nā kuhikuhi a kāu kauka, e hoʻēmi mālie ana i ka nui.
ʻEhia ka lōʻihi e ʻike ai i nā hopena o ka lāʻau lapaʻau?
He nīnau kēia a ka poʻe he nui e nīnau ai. Hiki ke hala ma kahi o 6 a 8 mau pule no ka ʻike ʻia ʻana o nā hopena piha o nā lāʻau SNRI. E hoʻomaka ʻoe e ʻike i kahi hoʻomaikaʻi ma hope o nā pule ʻelua a ʻekolu mua. No laila, he mea nui e hoʻomanawanui a hoʻohana pono i ka lāʻau. Inā ʻaʻole ʻoe e ʻike i kekahi ʻokoʻa ma hope o kēia manawa, e kamaʻilio me kāu kauka e pili ana i ia mea.
Leka Lawe-Home
- He papa lāʻau lapaʻau maikaʻi loa nā SNRI e mālama ai i nā kūlana e like me ke kaumaha, ka hopohopo, a me ka ʻeha mau loa.
- Hana kēia lāʻau lapaʻau ma ke kaulike ʻana i nā pae o nā ʻelele kemika i kapa ʻia ʻo serotonin a me norepinephrine i loko o ka lolo.
- ʻO nā hopena ʻaoʻao mua he manawa pōkole wale nō, akā inā hoʻopilikia lākou, e ʻōlelo pono e haʻi i kāu kauka.
- Mai ho'ōki koke i ka lawe ʻana i kēia lāʻau me ka ʻole o ke aʻo ʻana a kāu kauka.
- E makaʻala i nā hōʻailona weliweli o ka serotonin syndrome (ke kuni kiʻekiʻe, ka huikau, nā hopu ʻana). Inā loaʻa kēia, e hele koke i kahi lumi pilikia (ETU).
- Hiki ke lōʻihi ka manawa e loaʻa ai ka lāʻau kūpono nāu. No laila e hoʻomanawanui a e hoʻomau i ka launa pū ʻana me kāu kauka. Ua mākaukau mau kāu kauka e kōkua iā ʻoe.
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