Loaʻa iā ʻoe kahi makemake nui ʻole e ʻai? E aʻo kākou e pili ana i ka maʻi VIPoma (Vasoactive Intestinal Peptide Secreting)!

Loaʻa iā ʻoe kekahi manawa ka maʻi diarrhea koʻikoʻi e mau ana no nā lā, me ka ʻeha o ka ʻōpū a me nā ʻūpā? ʻAʻole paha ʻoe e ʻai a inu paha i kekahi mea, akā ke manaʻo nei ʻoe i kēia ʻano. Inā loaʻa iā ʻoe nā hōʻailona e like me kēia, he mea kakaikahi loa paha ke kumu, akā he ʻano paha ia e pono ai mākou e kamaʻilio e pili ana. I kēia lā, ke kamaʻilio nei mākou e pili ana i kekahi ʻano i kapa ʻia ʻo VIPoma , a i ʻole ka puʻupuʻu 'Vasoactive Intestinal Peptide Secreting' . ʻOiai paha he mea paʻakikī iki ka inoa, e mālama kākou i ka maʻalahi.

He aha ka puʻupuʻu VIPoma?

I ka ʻōlelo maʻalahi, he ʻano puʻupuʻu kakaikahi loa ka VIPoma e ulu ana i loko o ka pancreas . ʻO ke kikoʻī, ʻo ia nā puʻupuʻu e ulu ana i loko o nā pūnaewele hana hormone o ka pancreas, i kapa ʻia he mau pūnaewele endocrine . I kekahi manawa kapa nā kauka i kēia maʻi ʻo 'Verner-Morrison syndrome' .

He mea kākaʻikahi loa nā puʻupuʻu VIPoma. ʻOiai ma kahi ʻāina e like me ʻAmelika, ua ʻōlelo ʻia e loaʻa kēia ʻano ma kahi o hoʻokahi i loko o ka ʻumi miliona mau kānaka. No laila hiki iā ʻoe ke noʻonoʻo i kona kakaʻikahi. ʻO ka noho ʻana me ia maʻi kakaʻikahi hiki ke lilo i mea paʻakikī maoli, no ka mea, he hopena nui ia i kou ola o kēlā me kēia lā. Akā, mai hopohopo . I kēia manawa, aia nā lāʻau lapaʻau e hiki ai ke ho'ōla loa i kēia ʻano VIPoma, a i ʻole e kāohi i nā hōʻailona.

He aha nā hōʻailona o kahi puʻupuʻu VIPoma?

ʻO ka hōʻailona nui a koʻikoʻi loa i ʻike ʻia ma kēia ʻano, ʻo ia ka maʻi kahe nui a wai . He koʻikoʻi loa kēia a hiki iā ʻoe ke loaʻa i kēia maʻi kahe ʻoiai inā ʻaʻole ʻoe e ʻai ana (hoʻokē ʻai). ʻAʻole ia e emi i loko o kekahi mau lā. ʻO kēia ka hōʻailona ʻokoʻa loa o kēia maʻi.

Ma waho aʻe o kēlā, aia paha kekahi mau hōʻailona ʻē aʻe:

• ʻŌpū ʻeha a ʻeha paha: Manaʻo paha kou ʻōpū e like me ka huli ʻana a ʻeha paha ke hoʻopā aku.
• Luhi: Manaʻo luhi a make ke ola i nā manawa a pau.
• ʻUlaʻula: ʻUlaʻula koke o ka maka a me ka umauma. Hiki ke hana ʻia kēia me ke kumu ʻole.
• Nāwaliwali o nā ʻiʻo: Manaʻo paha ʻoe ua mae kou mau lālā, a he mea paʻakikī paha ke hāpai i nā mea kaumaha.

E noʻonoʻo pehea ʻoe e manaʻo ai inā e hāʻawi ʻoe i ʻelua a ʻekolu mau ʻōmole wai ma ke ʻano he ʻōpala i ka lā. Hiki i kēia ke koʻikoʻi loa a hiki ʻole iā ʻoe ke hana i kāu mau hana o kēlā me kēia lā.

He aha ke kumu e ulu ai ka VIPoma?

ʻAʻole maopopo i ka poʻe akamai ke kumu o nā maʻi VIPoma, akā ua maopopo iā lākou ke ʻano o ka puka ʻana o kēia mau hōʻailona.

He hormone ko ko kākou kino i kapa ʻia ʻo 'Vasoactive Intestinal Peptide' (VIP) . ʻO kēia hormone VIP ke kuleana no ka hoʻoponopono ʻana i kā kākou ʻōnaehana hoʻoheheʻe.He kōkua nui ia. ʻO ia hoʻi, ke kāohi nei kēia hormone i ka hoʻokuʻu ʻia ʻana o ka wai, nā paʻakai, nā enzymes, a me ka waikawa o ka ʻōpū i loko o ke ala ʻai. Kōkua pū ia i ka hoʻomaha ʻana i kekahi o nā ʻiʻo i loko o ke ala ʻai.

Ke ulu aʻe kahi puʻupuʻu VIPoma, hoʻokuʻu ia i kahi nui o ka hormone VIP i loko o ke kino. Ke komo kēia hormone VIP keu i loko o ke kino, ʻike ʻia nā hōʻailona i ʻōlelo ʻia ma mua, e like me ka maʻi diarrhea nui a me nā ʻeha o ka ʻōpū. I ka ʻōlelo maʻalahi, hoʻoulu kēia puʻupuʻu i ka hormone VIP e hana nui.

He aha nā pilikia e hiki mai ana o VIPoma?

ʻO ka pilikia nui me VIPoma ka maʻi kahe nui. Hiki i kekahi poʻe ke hoʻokuʻu i hoʻokahi a ʻekolu lita (1-3 kuata) o ka ʻōpala wai i ka lā. Ke hoʻomau kēia maʻi kahe, nalowale ke kino i ka nui o ka wai a me nā minelala koʻikoʻi, ʻoiai ka potassium.

Hiki i kēia ke alakaʻi i ka maloʻo a me ka hypokalemia i ka hala ʻana o ka manawa. He mea weliweli kēia mau kūlana ʻelua no ka mea hiki iā lākou ke alakaʻi i nā pilikia olakino koʻikoʻi. Eia kekahi laʻana:

• Ka puʻuwai kūpono ʻole (`Arrhythmia`): Puʻuwai kūpono ʻole.
• ʻO ka haʻalulu hypovolemic: He kūlana i hoʻokumu ʻia e ka emi ʻana o ka nui o ka wai i loko o ke kino.
• Ka nāwaliwali o nā ʻiʻo (`Myopathy`): Ka hana ʻino o nā ʻiʻo.
• Tetany: ʻEha ka ʻūlū ʻana o nā ʻiʻo.

Ma muli o kēia mau pilikia, he mea nui loa e ʻimi koke i ke kōkua lapaʻau inā loaʻa iā ʻoe nā hōʻailona o VIPoma.

Pehea e ʻike ai nā kauka i ka VIPoma?

Inā loaʻa iā ʻoe nā hōʻailona e like me ka maʻi kahe nui a i ʻole ka ʻeha ʻōpū i hala no kekahi mau lā, e hana ke kauka i kahi hoʻokolokolo kino a nīnau e pili ana i kāu mau hōʻailona.

Hiki ke hana ʻia kahi hoʻāʻo ʻana i ka ʻōpala e kāpae i nā maʻi maʻamau ʻē aʻe e hoʻoulu ai i ka maʻi diarrhea (e.g., nā maʻi). Eia kekahi, hiki ke hana ʻia nā hoʻāʻo aʻe:

• Nā hoʻāʻo koko: Nānā nui kēia i ka pae o ka hormone VIP i loko o ke koko. Ma VIPoma, kiʻekiʻe loa kēia pae. Hiki iā lākou ke nānā i nā mea e like me ka dehydration a me ka nele o ka potassium.
• Nā hoʻāʻo kiʻi: Lawe kēia i nā kiʻi o loko o ke kino e ʻike inā he puʻupuʻu, inā pēlā, ma hea ia, a pehea kona nui. Hiki i kēia ke komo pū me kahi hoʻāʻo 'Computed Tomography (CT) scan' a i ʻole 'Magnetic Resonance Imaging (MRI)' .

Ua hōʻoia nā kauka i ke kūlana VIPoma ma hope o ka hana ʻana i kēia mau hoʻokolohua a pau.

Pehea e mālama ʻia ai ʻo VIPoma?

ʻO ka maʻamau, ʻo ka mālama ʻana no ka VIPoma e pili ana i ka hui pū ʻana o nā lāʻau lapaʻau a me ke ʻoki kino. Hiki i kāu kauka ke ʻōlelo i kēia mau mea:

• Nā wai intravenous ('IV fluids'):Hāʻawi ʻia kēia mau mea e pani i nā wai a me nā minelala i nalowale mai ke kino ma muli o ka maʻi diarrhea mau. Hiki i kēia ke kōkua i ka kaohi ʻana i ka maloʻo ʻana o ka wai.
• Nā lāʻau lapaʻau:
• Hiki ke hoʻomalu ʻia ka maʻi kahe me nā lāʻau lapaʻau e like me ka "Octreotide (Sandostatin LAR®)" . Hoʻemi kēia mau lāʻau lapaʻau i ka hoʻokuʻu ʻia ʻana o ka hormone VIP.

Ma hope o ka mālama mua ʻana i kāu mau hōʻailona ma kēia ʻano, hiki i kāu kauka ke kuhikuhi i nā lāʻau ʻē aʻe e wehe a kāohi paha i ka puʻupuʻu:

• ʻOki kino: Inā ʻaʻole i pālahalaha ka puʻupuʻu i nā ʻāpana ʻē aʻe o ke kino (metastasized) , hiki ke hoʻohana ʻia ke ʻoki kino e wehe i ka puʻupuʻu. Hiki ke hoʻohana ʻia kahi ʻoki kino i kapa ʻia he distal pancreatectomy, kahi e wehe ai i ka huelo a me ke kino o ka pancreas, no kēia. Inā wehe loa ʻia ka puʻupuʻu, hiki ke ho'ōla ʻia ka maʻi.
• Kemoterapi: Inā ua pālahalaha ka puʻupuʻu a i ʻole ʻaʻole hiki ke wehe loa ʻia e ke ʻoki ʻana, hāʻawi ʻia ka chemotherapy e luku i nā hunaola kanesa.
• Lapaʻau i hoʻolālā ʻia: ʻO kēia nā lāʻau lapaʻau e hoʻolālā ana i nā ʻāpana kikoʻī o nā hunaola kanesa.

Na kāu hui lapaʻau e hoʻoholo i ka lāʻau kūpono loa nāu ma hope o ka nānā pono ʻana i kou kūlana.

He aha ka mea hiki i kekahi me VIPoma ke manaʻo?

ʻOkoʻa maoli kēia mai kēlā kanaka a kēia kanaka. Hiki i ke ʻoki kino ke ho'ōla loa i ka VIPoma. Hiki i ka lāʻau lapaʻau ke kaohi i nā hōʻailona i kahi nui.

Eia naʻe, ʻaʻole like ke kūlana o kēlā me kēia kanaka . He ʻokoʻa loa paha kou ʻike mai ko kekahi me VIPoma. ʻO kāu kauka lapaʻau a me ka hui lapaʻau ka poʻe hiki ke hāʻawi iā ʻoe i ka ʻike a me ke alakaʻi maikaʻi loa. ʻIke maikaʻi lākou iā ʻoe a me kou kūlana, no laila e nīnau iā lākou i nā mea āu e pono ai e ʻike.

Āhea wau e ʻike ai i ke kauka?

Inā ʻoe e loaʻa nei i ka lāʻau lapaʻau no VIPoma, e kāhea koke aku i kāu kauka inā ʻaʻole hoʻomaikaʻi kāu mau hōʻailona a inā paha e ʻoi aʻe ka ʻino.

Eia kekahi, e hele i kahi keʻena pilikia inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona:

• Inā loaʻa iā ʻoe ka ʻeha nui o ka ʻōpū .
• Inā ua loaʻa iā ʻoe ka maʻi kahe wai no kekahi mau lā .
• Inā ʻoe e hōʻike ana i nā hōʻailona o ka make wai , e like me ke poʻo māmā, ka manaʻo poniuniu, a i ʻole ka loaʻa ʻana o ka mimi melemele ʻeleʻele a ʻeleʻele paha.

ʻO ka maʻi palū mau i hoʻokumu ʻia e VIPoma hiki ke hoʻopilikia i kāu mau hana o kēlā me kēia lā a me kou hiamoe ʻana i ka pō. ʻO ka ʻike ʻana i ke kumu o kēia mau hōʻailona hiki ke lilo i mea hōʻoluʻolu. Eia naʻe, no ka mea he maʻi laha ʻole ʻo VIPoma, he kakaikahi ka poʻe i ʻike e pili ana i ia mea. Hiki i kēia ke waiho iā ʻoe me ka mehameha a me ka hoʻonāukiuki. Hiki paha iā ʻoe ke hilahila i nā hōʻailona o VIPoma.

Hoʻomaopopo maikaʻi kāu hui lapaʻau i kēia mau manaʻo, no laila mai kānalua e noi iā lākou no kekahi kōkua āu e pono ai, inā paha e pili ana i ka hoʻokele ʻana i kāu mau hōʻailona a i ʻole ke ola ʻana me ia maʻi laha ʻole.

Nā mea nui a mākou e hoʻomanaʻo ai (Leka Lawe-Home)

He puʻupuʻu laha ʻole ka VIPoma e ulu ana i loko o ka pancreas. Hoʻoulu ia i ka hoʻokuʻu nui ʻia ʻana o kahi hormone i kapa ʻia ʻo VIP, kahi e hoʻoulu ai i nā hōʻailona e like me ka maʻi diarrhea nui a me nā ʻeha ʻōpū. Inā hoʻomau kēia mau hōʻailona, ​​​​he mea nui e ʻimi i ke aʻo lapaʻau. He mea nui ka mālama koke ʻana no ka mea hiki ke loaʻa nā pilikia e like me ka dehydration a me ka nele o ka potassium. Aia nā lāʻau lapaʻau e like me ke ʻoki ʻana, ka lāʻau lapaʻau, a me ka chemotherapy. ʻOiai he maʻi laha ʻole kēia, ʻaʻole ʻoe hoʻokahi. E kiʻi i ke kākoʻo mai kāu hui lapaʻau.

ʻO VIPoma, Vasoactive Intestinal Peptide, Kanesa Pancreatic, Ka maʻi kahe, Verner-Morrison syndrome, Nā Hoʻohaʻahaʻa Hormonal, Nā Maʻi Kakaikahi