E makaʻala kākou i ka hopena weliweli i ka anesthesia (Malignant Hyperthermia)

E noʻonoʻo ʻoe ua hoʻokomo ʻia kekahi o kāu poʻe aloha i ka haukapila no kahi ʻoki maʻamau. Ke manaʻolana nei mākou a pau e holo pono nā mea āpau. Akā, ma hope o ka hāʻawi ʻia ʻana o ka anesthesia , piʻi koke ka mahana o ke kino me ka weliweli, ʻūlū nā ʻiʻo, a lilo ka puʻuwai i mea ʻē. ʻO kēia ka mea a mākou e kamaʻilio nei i kēia lā, he ʻano kakaikahi akā weliweli loa, he ʻano hoʻoweliweli i ke ola i kapa ʻia ʻo ' malignant hyperthermia '. He mea nui loa ka makaʻala i kēia.

I ka ʻōlelo maʻalahi, he aha ka Malignant Hyperthermia?

ʻO ka mea mua, e hoʻomaopopo kākou i ke ʻano o ka 'Hyperthermia'. ʻO ka Hyperthermia ka wā e piʻi nui ai ka mahana o ko kākou kino a ʻaʻole hiki iā kākou ke kāohi. ʻO ka maʻamau, mālama ʻia ka mahana o ko kākou kino ma kahi o 37 degere Celsius (98.6 Fahrenheit) ma o nā kaʻina hana e like me ka hou ʻana . Akā i ka hyperthermia, nalowale kēia kaohi a piʻi ka mahana ma luna o 40 degere Celsius (104 Fahrenheit). ʻAʻole kēia he kuni maʻamau, ʻoi aku ka weliweli.

ʻO ka maʻamau, hoʻokumu ʻia ka hyperthermia e nā kumu o waho e like me ke kiʻekiʻe o ka mahana a me ka dehydration ( nele i ka wai i loko o ke kino).

Akā, he mea ʻokoʻa ka Malignant Hyperthermia (MH) . Hana ʻia ia ke pane ʻē ke kino i kekahi ʻano anesthetics . He mea nui kēia mau anesthetics no ka hana ʻana i ke ʻoki ʻana me ka ʻeha ʻole. Akā i kekahi poʻe, hui pū kēia mau lāʻau me kahi kīnā genetic i loko o ke kino e hoʻoulu ai i kēia kūlana weliweli.

He aha ke kumu o ka hyperthermia malignant?

ʻO ke kumu nui o kēia kūlana he mau ʻano lāʻau hoʻomaha. I kekahi manawa hiki ke hana ʻia e ka hoʻoikaika kino nui a i ʻole nā ​​kūlana wela loa o ke kaiapuni. Ua kapa ʻia ʻo ia ʻo 'Awake Hyperthermia'.

ʻO ka mea nui , ʻoiai inā ua lawe kekahi i kēia mau lāʻau me ka ʻole o nā pilikia ma mua, hiki nō iā lākou ke loaʻa i kēia ʻano i ka manawa aʻe . No laila, he mea nui loa ka makaʻala i nā pilikia.

E nānā kākou i nā mea hoʻonāukiuki nui e hoʻoulu ai i kēia ʻano maʻi.

He aha nā hōʻailona o kēia maʻi?

Hoʻomaka pinepine kēia mau hōʻailona i ka wā a ma hope koke iho paha o ka lawelawe ʻia ʻana o ka anesthesia, no laila ua makaʻala nui nā kauka a me nā limahana ma ka lumi hana i kēia.

He aha ke kumu o ka hyperthermia malignant?

ʻO ke kumu nui o kēia, he kīnā hoʻoilina . I ka ʻōlelo maʻalahi, aia kahi kīnā i loko o nā genes e kaohi ana i ka hana ʻiʻo i loko o ko mākou kino. Hiki ke hoʻoilina ʻia kēia kīnā mai ka hānau ʻana mai, a i ʻole hiki ke hoʻāla ʻia ma hope o ke ola.

Ua ʻike nā kānaka ʻepekema ma mua o 80 mau kīnā genetic e hoʻoulu ai i kēia maʻi. He maʻi ia e hiki ke hoʻoili ʻia mai kēlā hanauna a i kēia hanauna . ʻO ke ʻano kēia, inā loaʻa i kou makuahine, makuakāne, kaikunāne a kaikuahine paha kēia maʻi, ʻoi aku ka nui o kou loaʻa ʻana iā ia. Eia kekahi, ʻoi aku ka nui o ka loaʻa ʻana o kēia maʻi i nā kāne ma mua o nā wahine.

Hiki ke ʻike mua inā paha he pilikia kēia?

ʻAe, aia ʻelua mau hoʻokolohua lapaʻau e hōʻoia inā aia kēia pilikia.

1. Hoʻāʻo Koko Genetic: Hiki ke lawe ʻia kahi laʻana o kou koko a hiki ke hoʻāʻo ʻia nā genes i loko e ʻike inā he mau kīnā genetic nui e pili ana i kēia. Eia naʻe, ʻaʻole pololei 100% kēia mau hoʻāʻo. ʻO kēia no ka mea hiki ke hana ʻia ke kūlana e nā kīnā genetic i ʻike ʻole ʻia.

2.ʻO ka Biopsy Muscle: ʻO kēia ka hoʻāʻo pololei loa. Ma kēia hoʻāʻo, lawe ke kauka i kahi ʻāpana liʻiliʻi o ka ʻiʻo mai kou wāwae a hoʻāʻo iā ia i loko o kahi keʻena hoʻokolohua e ʻike pehea e pane ai i nā lāʻau lapaʻau e hoʻoulu ai i ka MH. ʻAʻole hana ʻia kēia hoʻāʻo no nā mea āpau. Paipai wale nā ​​​​kauka i kēia hoʻāʻo inā loaʻa i kekahi o kou ʻohana ke kūlana a inā he mau hōʻailona kānalua kāu.

Pehea e mālama ai i kēia maʻi inā hiki koke mai?

He pilikia olakino ka Malignant Hyperthermia. ʻO ia hoʻi, pono e mālama koke ʻia. Inā loaʻa kekahi mea e like me kēia ma kahi lumi hana, e hana koke ke kime lapaʻau.

• ʻO ka mea mua e hana ai, ʻo ia ke hoʻōki koke i ka hāʻawi ʻana i ka anesthetic i hoʻokumu i ke kūlana .
• ʻO ka mea aʻe, ua hoʻokomo ʻia kahi lāʻau lapaʻau kūikawā i kapa ʻia ʻo ` Datrolene` ma o ka intravenous. ʻO kēia wale nō ka lāʻau lapaʻau hope loa no MH.
• Ua ʻōwili ʻia ka mea maʻi i loko o kahi pākeke hoʻoluʻu e hoʻohaʻahaʻa i ka mahana o ke kino. Hoʻokomo ʻia nā ʻeke hau ma nā wahi e like me nā ʻāʻī lima a me ka ʻūhā.
• Hāʻawi ʻia ka saline anu (nā wai IV anu) e hoʻomaʻalili i ke kino.
• Hoʻokomo ʻia ka mea maʻi i ka Intensive Care Unit (ICU) a i ʻole Emergency Treatment Unit (ETU) e nānā pono i ko lākou kūlana.

He aha kā mākou e hana ai e pale aku iā mākou iho mai kēia pilikia?

ʻAʻohe lāʻau lapaʻau no ke kīnā genetic ke kumu o kēia, no laila ʻo ka mea maikaʻi loa e hana ai, ʻo ia ka mālama ʻana i ka pilikia a pale i kahi ulia pōpilikia.

ʻO kēia ka mea nui e hoʻomanaʻo. Ke hoʻomaopopo mai ʻoe iā mākou, e hōʻoia nā kauka e hoʻohana wale i nā anesthetics palekana ʻaʻole e hoʻoulu i ka MH. No laila, he mea nui loa ka ʻike ʻana i ka mōʻaukala olakino o kou ʻohana.