Ke paʻakikī nei kou mau ʻiʻo e like me nā pōhaku? E kamaʻilio kākou e pili ana i kahi maʻi laha ʻole (Stiff Person Syndrome)

E noʻonoʻo ʻoe e noho wale ana a laila lilo koke kou mau ʻiʻo hope i ʻoʻoleʻa e like me ka pōhaku, ʻaʻole hiki ke neʻe. A i ʻole ʻo ka walaʻau iki a i ʻole kekahi e kuʻi ana iā ʻoe e hoʻoulu ai i kou kino e ʻūlū a me kou mau ʻiʻo e ʻūlū me ka ʻeha nui. ʻAʻole paha kēia he ʻeha kua wale nō a i ʻole he ʻeha ʻiʻo maʻamau. I kēia lā, ke kamaʻilio nei mākou e pili ana i kahi maʻi kakaikahi loa i lohe ʻole ʻia e ka poʻe he nui, akā he mea nui loa ia e ʻike. Ua kapa ʻia kēia ʻo Stiff Person Syndrome , a i ʻole SPS no ka pōkole.

I ka pōkole, he aha ka Stiff Person Syndrome (SPS)?

He maʻi neurological laha ʻole ka Stiff Person Syndrome. Hoʻopilikia ia i ko kākou lolo a me ke kaula kuamoʻo. I ka ʻōlelo maʻalahi, he maʻi autoimmune ia. ʻO ke ʻano kēia, ʻo ka ʻōnaehana pale, ka mea i manaʻo ʻia e pale i ko kākou kino mai nā maʻi, e hoʻomaka hewa ana e hoʻouka i kā kākou mau cell olakino ponoʻī. He mea laha ʻole kēia maʻi a hiki i kahi ʻāina e like me ʻAmelika Hui Pū ʻIa, aia ma lalo o 5,000 mau maʻi i ʻike ʻia me kēia maʻi.

ʻO ke kanaka me kēia maʻi e ʻike mua i ka manaʻo o ka paʻa i nā ʻiʻo o ka ʻaoʻao waena o ke kino, ʻo ia hoʻi, ka ʻāpana o ke kino . I ka hala ʻana o ka manawa, hiki i kēia paʻa ke laha i nā lima a me nā wāwae. Ma waho aʻe o kēia paʻa, hiki nō hoʻi ke loaʻa nā ʻeha ʻiʻo ʻeha loa. Ma muli o kēia paʻa, hiki ke loli ke kūlana o ke kino i ka hala ʻana o ka manawa, e kūlou iki ana i mua a me ke ʻano kūlou .

Hiki i kēia mau ʻūmiʻi ʻiʻo ke hana kū hoʻokahi a i ʻole e hoʻoulu ʻia e kekahi mea. No ka laʻana, ʻo kahi walaʻau nui koke, ke kuʻi ʻana o kekahi iā ʻoe, a i ʻole ke kaumaha nui hiki ke hoʻoulu i kēia mau ʻūmiʻi.

He aha nā hōʻailona nui o kēia maʻi?

ʻOiai ʻokoʻa iki nā hopena o kēia maʻi mai kēlā kanaka a kēia kanaka, aia kekahi mau hōʻailona maʻamau e ʻike ʻia. E nānā kākou iā lākou ma kahi papa.

No ke aha lā e hana ʻia ai kekahi mea e like me kēia?

ʻAʻole i loaʻa i nā kauka kahi kumu kūpono no kēia, akā ʻo ke kumumanaʻo nui, he pilikia ia me kā mākou ʻōnaehana pale .

Aia kekahi neurotransmitter i kapa ʻia ʻo GABA e kōkua ana i ka hoʻokele ʻana i ka neʻe ʻana o ko kākou mau ʻiʻo. E noʻonoʻo iā ia he 'switch' e hoʻouna ana i kahi hōʻailona i ko kākou mau ʻiʻo e 'hoʻomaha'. He mea nui ka enzyme i kapa ʻia ʻo 'glutamic acid decarboxylase (GAD)' no ka hana ʻana i kēia GABA. I ka hapa nui o nā maʻi SPS, hana ke kino i nā antibodies e hoʻouka i kēia enzyme GAD. Ke hele kēia mau antibodies a luku i ka enzyme GAD, ʻaʻole i hana pono ʻia ʻo GABA. A laila, ʻaʻole loaʻa i nā ʻiʻo ka leka e 'hoʻomaha' pono, a lilo lākou i ʻūlū a me ka wili mau.

ʻOi aku ka nui o ka poʻe me SPS i loaʻa i nā maʻi autoimmune ʻē aʻe.

• Vitiligo - nā ʻāpana keʻokeʻo ma ka ʻili
• ʻAno 1 Diabetes
• Anemia pernicious - Anemia i hoʻokumu ʻia e ka nele o ka wikamina B12
• ʻO ka maʻi thyroid (ka maʻi o ka ʻōpū thyroid)

Eia kekahi, ʻo ka poʻe me kekahi ʻano maʻi kanesa e pilikia ana i ka loaʻa ʻana o SPS (e like me ka māmā, ka puʻupaʻa, ka umauma, ka thyroid, ka maʻi kanesa colon).

Pehea e ʻike pololei ai ke kauka i kēia maʻi?

ʻIke pinepine ʻia nā hōʻailona SPS ma waena o 30 a me 60 mau makahiki. ʻOi aku ka pālua o ka loaʻa ʻana o ka maʻi i nā wahine ma mua o nā kāne.

Ma muli o ka like o nā hōʻailona o kēia maʻi me nā maʻi maʻamau ʻē aʻe, ua kuhihewa pinepine ʻia ʻo SPS no kekahi maʻi ʻē aʻe.

• Sclerosis lehulehu
• ka maʻi o Parkinson
• ʻO ka Fibromyalgia
• ʻO ka dystrophy muscular
• Hopohopo

Ma muli o kēia, hiki ke lōʻihi ka manawa e loaʻa ai kahi hōʻailona pololei. E nānā mua kāu kauka iā ʻoe, e nīnau e pili ana i kou mōʻaukala olakino, a laila e kauoha i kekahi mau hoʻokolohua e kāpae i nā kūlana ʻē aʻe.

1. Hoʻāʻo koko no nā antibodies GAD: ʻO kēia ka hoʻāʻo koʻikoʻi loa. Hiki ke loaʻa nā pae kiʻekiʻe o kēia mau antibodies GAD i loko o ke koko o 60% - 80% o nā maʻi SPS.

2. Electromyography (EMG): Ke ana kēia i ka hana uila o kou mau ʻiʻo i ka wā e hoʻomaha ai a i ka wā e ʻūlū ai. Noho ikaika nā ʻiʻo o nā maʻi SPS ʻoiai ke hoʻomaha nei lākou.

He aha nā lāʻau lapaʻau no kēia?

ʻO ka mea mua e ʻōlelo ai, ʻaʻohe lāʻau lapaʻau no kēia maʻi i kēia manawa . Eia nō naʻe, he nui nā lāʻau lapaʻau kūpono e hiki ke kōkua i ka kaohi ʻana i nā hōʻailona a kōkua iā ʻoe e hoʻomau i kāu mau hana o kēlā me kēia lā. Hoʻopilikino ʻia ka hoʻolālā lapaʻau no kēlā me kēia maʻi, ma muli o kā lākou mau hōʻailona.

E ho'āʻo kāu kauka i nā lāʻau lapaʻau like ʻole e kāohi i ka ʻeha a me nā ʻūmiʻi ʻiʻo. ʻAʻole like ka pane ʻana o ke kino o kēlā me kēia kanaka i nā lāʻau lapaʻau, no laila e lōʻihi paha ka manawa e ʻike ai i ka hui kūpono o nā lāʻau lapaʻau nāu.

• No ka ʻoʻoleʻa o nā ʻiʻo: Hoʻohana pinepine ʻia nā Benzodiazepines (e.g. diazepam, clonazepam) a me ka baclofen.
• No ka ʻeha: Hiki i nā lāʻau hoʻopau ʻeha a me kekahi mau lāʻau anti-seizure ke kōkua i ka kaohi ʻana i ka ʻeha.
• Lapaʻau Intravenous Immunoglobulin (IVIG): Pili kēia i ka hāʻawi ʻana i nā antibodies i lawe ʻia mai nā poʻe olakino ma o ka intravenous. Ua hōʻike ʻia hoʻi kēia he lāʻau lapaʻau kūpono no ka kaohi ʻana i nā hōʻailona SPS.

Ma waho aʻe o ka lāʻau lapaʻau, ka hoʻoikaika kino, nā hoʻomaʻamaʻa hoʻolōʻihi, ka massage, a me ka acupunctureHiki i nā mea e like me kēia ke kōkua i ka hōʻemi ʻana i ka ʻeha a hoʻomau i ka hana ʻana o nā ʻiʻo.