Puas yog koj tus menyuam muaj qaug dab peg tam sim ntawd? Cia peb kawm txog Cortical Dysplasia!

Koj tus me nyuam puas muaj mob qaug dab peg tam sim ntawd? Los yog puas muaj leej twg koj paub muaj cov tsos mob qaug dab peg no? Qee zaum peb ntshai heev thaum peb pom cov no, puas yog? Ib qho laj thawj rau qhov no yuav yog mob hlwb uas koj tsis tau hnov ​​​​dua. Hnub no peb yuav tham txog ib qho mob zoo li no, uas yog Cortical Dysplasia . Txawm hais tias lub npe yuav zoo li nyuaj me ntsis, cia peb piav qhia.

Cortical dysplasia yog dab tsi?

Hais yooj yim xwb, cortical dysplasia yog ib yam mob tsis tshua muaj uas ua rau qaug dab peg . Cov kws kho mob qee zaum hu nws ua focal cortical dysplasia, lossis (FCD). Nws hais tias "co-ticle" thiab "dys-pla-sia."

Qhov mob no cuam tshuam rau koj lub hlwb cortex . Ntawd yog, txheej sab nraud tshaj plaws ntawm peb lub hlwb. Xav txog, lub hlwb cortex no tswj ntau yam tseem ceeb xws li peb lub cev txav mus los, peb txoj kev xav, kev hais lus, kev nco, kev txawj ntse, thiab tus cwj pwm. Nws zoo li 'CPU' ntawm peb lub khoos phis tawj.

Lo lus kho mob "dysplasia" txhais tau hais tias kev loj hlob tsis zoo ntawm cov hlwb hauv lub cev. Yog li, rau ib tus neeg uas muaj cortical dysplasia, cov hlwb hauv lub cerebral cortex, lossis cov hlwb, tsis loj hlob zoo. Qhov no tshwm sim thaum tus menyuam tseem nyob hauv plab .

Cov hom kab mob cortical dysplasia tseem ceeb yog dab tsi?

Cov kws kho mob faib qhov mob no, hu ua cortical dysplasia, ua peb hom tseem ceeb, nyob ntawm seb qhov twg ntawm lub cerebral cortex (lobes) raug cuam tshuam, lossis cov cell txawv txav tsim li cas hauv lub hlwb.

Hom 1

Hauv hom no, cov hlwb tsis zoo li qub tau tsim nyob rau hauv koj lub cortex, lossis cov hlwb hlwb uas tsis tau teeb tsa raws li lawv yuav tsum tau ua. Qhov no tuaj yeem cuam tshuam rau txhua qhov ntawm lub hlwb. Tab sis nws feem ntau tshwm sim hauv lub temporal lobe , uas yog ib feem ntawm lub hlwb uas nyob rau ntawm pob ntseg, lossis lub frontal lobe , uas yog ib feem uas nyob rau ntawm lub hauv pliaj.

Hom 2

Hauv hom no, cov hlwb hauv lub paj hlwb cortex loj dua li qub, lossis muaj qhov tsos txawv. Hom thib ob no nyuaj dua thiab hnyav dua li hom thawj. Nws kuj feem ntau cuam tshuam rau lub hauv paus pem hauv ntej thiab lub sijhawm.

Hom 3

Hom no tshwm sim thaum koj muaj cortical dysplasia hom 1 lossis hom 2 thiab lwm yam kev txawv txav hauv lub hlwb. Piv txwv li, nws tuaj yeem tshwm sim nrog cov qog hauv hlwb, cov hlab ntsha tsis zoo, lossis cov qhov txhab hauv hlwb. Qhov ntawm lub hlwb uas raug cuam tshuam nyob ntawm qhov chaw uas cov qog nyob lossis thaj chaw ntawm lub hlwb uas tau raug puas tsuaj.

Cov tsos mob yog dab tsi? Koj paub nws li cas ?

Hauv cov kab mob cortical dysplasiaCov tsos mob tseem ceeb thiab feem ntau yog qaug dab peg. Qhov no yog qhov peb hu ua qaug dab peg. Tus mob qaug dab peg no tuaj yeem muaj ntau hom sib txawv:

• Kev Qaug Zog Hauv Lub Zeem Muag: Cov no pib ntawm ib sab ntawm lub hlwb. Lawv tsis kis mus rau sab tod. Tej zaum koj yuav muaj tej yam xws li co thiab tshee thaum lub sijhawm no. Tab sis tsis yog txhua tus neeg nkag siab qhov ntawd. Tej zaum koj tsuas yog xav tias txawv lossis txawv xwb.
• Tonic-clonic (Grand Mal) Qaug dab peg: Hom qaug dab peg no cuam tshuam rau ob sab ntawm lub hlwb. Qhov no yog thaum lub cev co thiab tsis tuaj yeem tswj tau. Nws cuam tshuam rau ob sab ntawm lub cev.
• Mob Qaug Dab Peg Rau Me Nyuam Mos: Qhov no yog ib hom mob qaug dab peg tshwj xeeb uas tsuas yog tshwm sim rau cov menyuam mos hnub nyoog qis dua ib xyoos xwb . Hauv qhov no, tus menyuam mam li ncab lawv txhais tes, ceg, thiab caj dab tawm, tom qab ntawd maj mam rub lawv rov qab dua. Zoo li lawv qaug dab peg. Qhov no tuaj yeem tshwm sim ntau zaus hauv ib hnub.

Qhov tseem ceeb yog tias cov qaug dab peg no tuaj yeem pib thaum twg los tau hauv lub neej. Ib txhia neeg pib muaj lawv thaum yau, thaum lawv tseem yog menyuam yaus. Tab sis ib txhia neeg tuaj yeem muaj lawv thawj zaug qaug dab peg tom qab hauv lub neej.

Ntxiv nrog rau tus kab mob qaug dab peg, koj yuav muaj lwm cov tsos mob:

• Nyuaj siab tsom ntsoov, tsis muaj peev xwm khaws lub siab rau ib qho chaw .
• Nyuaj kawm tej yam tshiab thiab cov tswv yim tshiab.
• Cov leeg nqaij tsis muaj zog ntawm ib sab ntawm lub cev (hemiparesis).

Kev puas tsuaj ntawm lub hlwb kuj tseem tuaj yeem cuam tshuam rau lub cev ntawm lub hlwb. Tab sis tus kws kho mob tsuas yog tuaj yeem pom cov kev hloov pauv no nrog kev ntsuas MRI, uas yog tib txoj hauv kev los txheeb xyuas qhov tseeb ntawm cov kev hloov pauv hauv lub cortex (grey matter) ntawm lub hlwb.

Vim li cas qhov xwm txheej no thiaj tshwm sim? Yog vim li cas?

Cortical dysplasia yog ib qho mob caj ces . Qhov no txhais tau tias vim muaj kev hloov pauv ntawm cov noob caj ces, lub hlwb tsis loj hlob li qub thaum lub sijhawm embryonic, uas yog, thaum tus menyuam loj hlob hauv plab.

Tiamsis cov kws tshawb nrhiav tseem tsis tau hais meej tias kev hloov pauv caj ces ua rau muaj qhov no. Lawv tseem tab tom tshawb nrhiav seb puas muaj tej yam ua rau muaj qhov no.

Muaj ib txhia kws tshaj lij ntseeg tias Hom 2 cortical dysplasia yog tshwm sim los ntawm kev hloov pauv hauv ib lub noob hu ua MTOR pathway . Cov noob no tsim cov protein uas pab peb cov hlwb, tshwj xeeb tshaj yog cov hlwb hlwb, loj hlob thiab txhim kho. Yog li ntawd, yog tias muaj kev hloov pauv hauv MTOR gene, nws tuaj yeem ua rau cov hlwb tsis zoo loj hlob.

Cov kws kho mob kuaj qhov no li cas? (Kev kuaj mob)

Tus kws kho mob kuaj mob cortical dysplasia los ntawm kev kuaj duab tshwj xeeb .

Koj yuav tsum qhia rau koj tus kws kho mob txog koj cov tsos mob thiab thaum twg koj thawj zaug pom lawv. Yog tias ua tau, nws yog ib qho tseem ceeb kom qhia meej txog koj cov mob qaug dab peg (piv txwv li lawv pib li cas, lawv kav ntev npaum li cas, muaj dab tsi tshwm sim rau lub sijhawm ntawd, thiab lwm yam) vim tias cov ntsiab lus no tuaj yeem pab koj kuaj mob.Tus kws kho mob tuaj yeem txheeb xyuas seb hom no yog hom twg.

Tus kws kho mob mam li thaij duab ntawm koj lub hlwb kom pom seb puas muaj cov hlwb tsis zoo lossis tsis sib luag hauv lub cerebral cortex. Cov kev kuaj uas lawv siv tau rau qhov no yog:

• `MRI (Magnetic Resonance Imaging):` Qhov no tuaj yeem thaij tau cov duab ntawm lub hlwb kom meej heev .
• `EEG (Electroencephalogram)`: Qhov no ntsuas qhov ua haujlwm hluav taws xob ntawm lub hlwb. Qhov no pab nrhiav qhov chaw ntawm tus kab mob qaug dab peg.
• `MEG (Magnetoencephalography):` Qhov no yog ib qho kev xeem uas saib xyuas kev ua haujlwm ntawm lub hlwb, ib yam li `EEG`.
• PET scan (Positron Emission Tomography scan)
• `Kev luam theej duab SPECT (Kev luam theej duab Photon Emission Computed Tomography ib zaug xwb)`

Tag nrho cov kev ntsuam xyuas no tsuas yog saib seb muaj dab tsi tshwm sim hauv lub hlwb.

Muaj kev kho mob dab tsi?

Koj tus kws kho mob yuav pom zoo kom koj siv tshuaj kho mob los tswj koj cov tsos mob thiab txo qhov zaus ntawm kev qaug dab peg.

Lawv feem ntau yuav pib nrog cov tshuaj tiv thaiv kev qaug dab peg . Tab sis ntawm no yog qhov teeb meem. Cortical dysplasia qee zaum tuaj yeem ua rau muaj kev qaug dab peg uas tsis kam siv tshuaj. Qhov ntawd txhais tau tias nws tuaj yeem nyuaj me ntsis rau kev tswj hwm nrog tshuaj dua li nrog kev qaug dab peg ib txwm muaj. Txawm hais tias cov tshuaj yuav ua haujlwm thaum xub thawj, nws tuaj yeem ua haujlwm tsawg dua raws sijhawm.

Kev ua raws li kev noj zaub mov ketogenic (lossis kev noj zaub mov keto) yuav pab txo qhov zaus ntawm kev qaug dab peg. Qhov no suav nrog kev noj zaub mov uas muaj roj ntau thiab tsawg cov carbohydrates. Qhov no hloov txoj kev uas lub hlwb tau txais lub zog. Koj tuaj yeem nrhiav kev pab los ntawm tus kws noj zaub mov kom pab koj hloov mus rau hom kev noj zaub mov no.

Yog tias lwm yam kev kho mob tsis tswj tau koj tus mob qaug dab peg zoo, tej zaum koj yuav tsum tau phais mob qaug dab peg . Koj tus kws phais yuav piav qhia seb koj yuav phais hom twg thiab yuav tsum xav li cas.

Puas yog qhov mob no raug tshem tawm tag nrho los ntawm kev phais?

Koj tus kws phais yuav muaj peev xwm tshem tawm qhov mob no. Qhov no yuav nyob ntawm ntau yam:

• Koj muaj hom kab mob cortical dysplasia li cas?
• Kab mob qaug dab peg pib qhov twg hauv lub hlwb?
• Qhov hnyav ntawm tus mob dysplasia.

Yog tias tus kws phais mob tuaj yeem tshem tawm cov hlwb tsis zoo uas tsis ua rau koj lub hlwb ua haujlwm tsis zoo, qhov ntawd zoo heev. Kev tshem tawm cov hlwb no tuaj yeem txo qhov zaus ntawm kev qaug dab peg thiab txo cov tshuaj uas koj yuav tsum tau noj. Txawm li cas los xij, qee zaum thaum koj yuav tsum tshem tawm tag nrho cov hlwb tsis zoo ntawd, koj yuav tsum tshem tawm qee cov ntaub so ntswg zoo hauv lub hlwb thiab.Yog qhov no tshwm sim, koj lub peev xwm txav mus los, pom kev, thiab hnov ​​lwm yam kev xav yuav raug cuam tshuam. Koj tus kws phais yuav piav qhia txhua qhov zoo thiab qhov tsis zoo ntawm qhov phais no rau koj thiab pab koj txiav txim siab seb nws puas yog rau koj.

Lwm txoj kev yog cais cov hlwb txawv txav no tawm ntawm lwm qhov ntawm lub hlwb. Qhov no tiv thaiv kev kis tus kab mob qaug dab peg ntawm cov hlwb ntawd. Qee zaum, tus kws phais kuj tseem tuaj yeem rhuav tshem cov hlwb txawv txav no nrog "kev kho mob laser", uas tsis muaj kev pheej hmoo thiab tsis cuam tshuam ntau dua li kev phais hlwb ib txwm muaj.

Cortical dysplasia loj npaum li cas?

Txhua yam mob uas cuam tshuam rau lub hlwb tuaj yeem ua rau mob hnyav. Cortical dysplasia yog ib qho mob zoo li no. Tab sis tsis txhob txhawj . Koj tus kws kho mob yuav nrhiav txoj hauv kev los tswj koj tus mob qaug dab peg thiab lwm yam tsos mob. Maj mam, koj yuav muaj peev xwm txo qhov cuam tshuam ntawm tus mob no rau koj lub neej txhua hnub.

Qhov no puas kho tau tag nrho?

Nws muaj peev xwm ua tau, tshwj xeeb tshaj yog tom qab phais mob, uas koj yuav tsis muaj qaug dab peg dua li. Qhov ntawd yog ib qho teeb meem loj!

Txawm li cas los xij, cortical dysplasia tsis yog "kev kho mob" zoo li kev noj tshuaj rau mob khaub thuas. Kev kho mob tsom mus rau kev tswj cov tsos mob thiab qaug dab peg ntau dua li kev nrhiav kev kho .

Lub neej yuav zoo li cas nrog qhov xwm txheej no?

Feem ntau cov kab mob cortical dysplasia tsis ua rau muaj teeb meem loj lossis cuam tshuam rau koj lub neej. Qhov ntawd yog xov xwm zoo. Txawm li cas los xij, yog tias koj muaj qaug dab peg hnyav heev (tshwj xeeb tshaj yog tonic-clonic qaug dab peg), nws tuaj yeem ua rau koj muaj feem yuav tuag sai dua me ntsis . Yog tias koj txhawj xeeb txog qhov no yuav cuam tshuam li cas rau koj txoj kev noj qab haus huv mus sij hawm ntev, tham nrog koj tus kws kho mob. Nws tuaj yeem pab koj kom muaj kev nyab xeeb thiab noj qab nyob zoo.

Thaum twg peb yuav tsum mus ntsib kws kho mob?

Koj tus kws kho mob yuav qhia rau koj tias koj yuav tsum rov qab los ntau zaus npaum li cas ('kev mus ntsib kws kho mob tom qab') thiab koj yuav tsum tau kuaj dab tsi. Thaum pib, tshwj xeeb tshaj yog tom qab pib kho mob thiab ua ntej thiab tom qab phais, koj yuav tsum tau mus ntsib koj tus kws kho mob ntau zaus dua.

Tseem Ceeb: Yog tias koj muaj qaug dab peg ntau dua, lossis yog tias lawv zoo li hnyav dua li yav dhau los, nco ntsoov qhia rau koj tus kws kho mob . Nws yuav yog ib qho cim qhia tias koj txoj kev kho mob yuav tsum tau hloov, lossis koj yuav muaj qaug dab peg uas tsis kam tshuaj.

Yuav ua li cas thaum muaj xwm txheej ceev?

Yog koj muaj qaug dab peg ntev tshaj tsib feeb, lossis yog koj muaj qaug dab peg ntau zaus sib law liag, hu rau 911 (lossis koj tus xov tooj xwm txheej ceev hauv zos) tam sim ntawd. Qhov no yog xwm txheej ceev.

Cov lus nug tseem ceeb uas yuav tsum nug koj tus kws kho mob

Thaum koj mus ntsib koj tus kws kho mob, tsis txhob yig nug cov lus nug zoo li no:

• Kuv muaj hom cortical dysplasia twg?
• Cov tshuaj kho mob qaug dab peg puas yuav ua haujlwm rau kuv?
• Thaum twg kuv yuav tsum xav txog kev phais?
• Hom kev phais twg zoo tshaj plaws rau kuv?

Nws nyuaj rau xav txog tias ob peb lub hlwb me me hauv lub hlwb yuav muaj feem cuam tshuam loj npaum li cas rau peb txoj kev noj qab haus huv. Tab sis, nug koj tus kws kho mob lossis kws phais mob yog tias koj muaj lus nug lossis kev txhawj xeeb . Lawv yuav piav qhia txhua yam uas koj xav paub txog yam uas tshwm sim hauv koj lub hlwb thiab lub cev, thiab lawv tuaj yeem ua dab tsi los pab koj kom zoo siab dua.

Nov yog cov ntsiab lus luv luv ntawm yam peb tau tham txog (Cov Lus Coj Mus Tsev):

Zoo, yog li tam sim no koj nkag siab zoo dua txog Cortical Dysplasia uas peb tau tham txog hnub no. Nco ntsoov:

• Qhov no yog ib qho mob uas tshwm sim thaum cov hlwb hlwb tsis loj hlob zoo thiab tuaj yeem ua rau muaj mob qaug dab peg .
• Qhov no yuav yog vim muaj cov laj thawj caj ces .
• Cov tsos mob tseem ceeb yog ntau hom kev qaug dab peg .
• Qhov no raug kuaj pom los ntawm kev kuaj tshwj xeeb xws li MRI.
• Cov kev xaiv kho mob suav nrog tshuaj, kev noj zaub mov ketogenic, thiab, yog tias tsim nyog, phais .
• Es tsis txhob tham txog kev "kho kom zoo tag nrho", nws yog ib qho tseem ceeb kom tswj tau cov tsos mob .
• Koj ua tau lub neej li qub nrog tus mob no, tab sis koj yuav tsum ceev faj txog kev qaug dab peg hnyav.
• Nws yog ib qho tseem ceeb heev uas yuav tsum sib cuag nrog koj tus kws kho mob tsis tu ncua thiab ua raws li nws cov lus qhia.

Yog koj lossis ib tug neeg koj paub muaj cov tsos mob no, tsis txhob yig mus ntsib kws kho mob kom tau lus qhia. Kev kuaj mob thaum ntxov thiab kev kho mob tuaj yeem ua qhov sib txawv loj.

` Cortical Dysplasia, Epilepsy, Qaug dab peg, Cov Kab Mob Hlwb, Focal Cortical Dysplasia, Qaug dab peg, Qaug dab peg, Qaug dab peg thaum yau, Cov Kab Mob Genetic