Fibrosarcoma: Cia peb kawm ntxiv txog tus mob qog noj ntshav tsawg no

Thaum koj pom ib lub qog tshiab los yog qog nqaij hlav ntawm koj lub cev, tshwj xeeb tshaj yog ntawm koj ceg lossis caj npab, koj xav li cas? Feem ntau, peb xav tias nws yog ib txwm muaj thiab peb tsis quav ntsej txog nws. Tab sis qee zaum, txawm tias qee yam me me li ntawd los kuj yog ib yam dab tsi uas peb yuav tsum tau them sai sai. Hnub no, peb yuav tham txog ib hom mob qog nqaij hlav uas tsis tshua muaj neeg paub uas tuaj yeem tshwm sim ua ib lub qog. Qhov no hu ua fibrosarcoma.

Hais yooj yim xwb, fibrosarcoma yog dab tsi?

Fibrosarcoma yog ib hom mob qog nqaij hlav uas tsis tshua muaj neeg pom uas tshwm sim hauv cov nqaij mos. Hauv kev kho mob, peb hu qhov no ua sarcoma. Tam sim no koj yuav xav paub tias cov nqaij mos yog dab tsi. Nws yooj yim heev. Nws yog cov nqaij uas txuas thiab tuav ua ke ntau qhov ntawm peb lub cev. Yog xav kom meej, cov khoom xws li cov leeg thiab cov leeg uas txuas cov khoom xws li cov pob txha thiab cov leeg hauv peb lub cev yog cov khoom siv sib txuas no.

Mob qog nqaij hlav fibrosarcoma feem ntau tshwm sim hauv cov nqaij mos mos tob hauv lub cev. Nws feem ntau tshwm sim hauv ob txhais ceg (nyob ib ncig ntawm lub duav lossis pob txha ncej puab), caj npab sab saud, hauv caug, lossis lub cev. Nws kuj tsis tshua tshwm sim hauv lub taub hau lossis caj dab. Qee zaum, mob qog nqaij hlav no kuj tuaj yeem tshwm sim hauv cov pob txha lossis hauv cov ntaub so ntswg fibrous uas npog cov pob txha.

Yog tias koj lossis koj tus menyuam tau txais qhov kev kuaj mob no, qhov yuav tshwm sim tom ntej no nyob ntawm ntau yam. Koj lub hnub nyoog, qhov loj ntawm tus mob qog noj ntshav, thiab qhov chaw nws nyob yuav ua lub luag haujlwm. Koj tus kws kho mob yuav piav qhia txhua yam raws li koj qhov kev kuaj mob.

Muaj ob hom tseem ceeb ntawm qhov no.

Fibrosarcoma muaj ob hom loj. Ob hom no txawv heev.

Cov tsos mob ntawm tus kab mob no yog dab tsi?

Feem ntau nws yuav siv sijhawm ntev me ntsis kom cov tsos mob ntawm fibrosarcoma tshwm sim. Vim tias cov qog no loj hlob hauv cov nqaij mos mos tob hauv lub cev, koj yuav tsis pom dab tsi kom txog thaum cov qog loj hlob txaus kom nias rau ntawm cov hlab ntsha lossis cov hlab ntsha ze.

Cov no yog cov tsos mob uas feem ntau pom:

• Ib lub pob mos mos uas tsis mob lossis mob me ntsis: Qhov no tuaj yeem tshwm sim ntawm ob txhais ceg, caj npab, lossis lub cev.
• Ib qho kev xav tingling lossis mob ntse, mob threading: Qee zaum peb hais tias "pins and needles." Qhov no yuav yog vim muaj kev nias rau ntawm cov hlab ntsha ze ntawm lub qog.
• Kev o tsis zoo li qub: Hom kev o no tuaj yeem tshwm sim thaum lub qog ua rau cov hlab ntsha nias.

Cov tsos mob no yuav zoo ib yam li lwm yam mob uas tsis hnyav heev, yog li tsuas yog kws kho mob thiaj li paub tseeb tias cov kev hloov pauv no yog vim fibrosarcoma lossis lwm yam mob uas tsis yog mob qog noj ntshav (benign).

Cov ua rau thiab cov yam ntxwv uas ua rau muaj mob fibrosarcoma yog dab tsi?

Cov kws tshawb nrhiav tseem tsis tau paub meej tias yog dab tsi ua rau muaj mob fibrosarcoma. Txawm li cas los xij, ntseeg tau tias kev hloov pauv caj ces hauv cov cell ua lub luag haujlwm. Hais yooj yim, kev hloov pauv tshwm sim hauv DNA hauv peb cov cell. Cov kev hloov pauv no ua rau cov cell faib sai thiab tsis tuaj yeem tswj tau, tsim cov qog nqaij hlav.

Muaj ib qho kev hloov pauv ntawm cov noob caj noob ces uas pom tau tias muaj nyob rau hauv cov menyuam yaus uas muaj mob fibrosarcoma. Kwv yees li 90% ntawm cov no muaj feem cuam tshuam nrog cov teeb meem hauv tsev neeg noob caj noob ces NTRK. Thaum cov noob caj noob ces no tsis ua haujlwm zoo, cov qog nqaij hlav tuaj yeem tshwm sim.

Cov yam uas ua rau muaj kev pheej hmoo ntau ntxiv

Cov kws tshawb nrhiav tau pom tias qee yam mob uas los ntawm noob caj ces yuav ua rau muaj kev pheej hmoo ntawm kev mob fibrosarcoma.

• Tsev neeg adenomatous polyposis
• Li-Fraumeni syndrome
• Kab mob Neurofibromatosis hom 1 `(Neurofibromatosis hom 1)`
• Kab mob qog nqaij hlav basal cell carcinoma syndrome
• Retinoblastoma
• Kab mob sclerosis ntawm cov hlab ntsha
• Werner syndrome (Werner syndrome)

Tsis tas li ntawd xwb, tej zaum yuav muaj lwm yam mob uas cuam tshuam nrog qhov no:

• Mob pob txha infarction (kev tuag ntawm cov hlwb pob txha vim yog cov ntshav ntws mus rau cov pob txha tsawg dua)
• Kev kis kab mob pob txha ntev (Chronic osteomyelitis)
• Kev puas tsuaj ntawm cov fibrous dysplasia
• Kab mob Paget ntawm pob txha

Tseem muaj tej yam uas ua rau muaj kev pheej hmoo rau ib puag ncig thiab koj keeb kwm kev kho mob yav dhau los:

• Tau txais kev kho mob hluav taws xob rau thaj chaw uas muaj mob qog noj ntshav ua ntej lawm.
• Kub hnyiab hnyav qhov chaw muaj mob qog noj ntshav.
• Kev raug rau qee yam tshuaj lom neeg, xws li thorium dioxide, vinyl chloride, lossis arsenic.
• Kev raug rau cov khoom hlau (piv txwv li chromium, cobalt, nickel) uas ntxig rau hauv lub cev los ntawm kev phais.

Tus kws kho mob kuaj qhov no li cas? (Kev kuaj mob)

Cov kws kho mob ua ntau yam kev kuaj mob los kuaj mob fibrosarcoma. Cov ntaub ntawv los ntawm cov kev kuaj mob no txiav txim siab theem thiab qib ntawm tus mob qog noj ntshav.

• Kev kuaj MRI (Magnetic Resonance Imaging): Qhov no yog qhov kev kuaj duab uas siv ntau tshaj plaws los kuaj mob fibrosarcoma. Nws tuaj yeem qhia meej meej qhov loj thiab qhov chaw ntawm lub qog, thiab seb nws puas cuam tshuam rau cov hlab ntsha lossis cov hlab ntsha.
• CT scan (Computed Tomography scan): Qhov no siv cov duab X-ray thiab lub computer los tsim cov duab peb-seem (3D) ntawm koj cov nqaij mos thiab pob txha.
• Kev kuaj mob los ntawm koob txhaj tshuaj: Qhov no suav nrog kev tshem tawm ib daim nqaij me me ntawm lub qog (core needle biopsy) lossis tag nrho lub qog (excisional biopsy) rau kev kuaj mob. Tus kws kho mob kuaj xyuas cov nqaij hauv chav kuaj mob kom pom tias nws puas muaj cov hlwb qog.
• Immunohistochemistry (IHC): Qhov no yog kev kuaj mob tshwj xeeb hauv chav kuaj mob uas siv cov protein hu ua antibodies los xyuas kom meej tias qhov qog nqaij hlav yog fibrosarcoma lossis lwm hom mob qog nqaij hlav ntawm cov nqaij mos.

Cov theem ntawm mob qog noj ntshav raug txiav txim siab li cas?

Cov kws kho mob faib cov mob qog noj ntshav ua theem kom paub seb nws kis mus deb npaum li cas thiab nws hnyav npaum li cas. Qhov no suav nrog qhov loj ntawm lub qog, nws qhov chaw nyob, thiab seb nws puas kis mus. Lawv kuj saib "qib" ntawm mob qog noj ntshav. Qhov no yog qhov txawv txav ntawm cov hlwb qog noj ntshav thaum saib hauv qab lub tshuab microscope. Cov hlwb uas zoo li txawv txav raug suav hais tias yog cov qog noj ntshav "qib siab", uas tuaj yeem ua rau mob hnyav dua.

Koj tus kws kho mob yuav piav qhia rau koj seb qhov tshwm sim yuav zoo li cas tom qab kev kho mob, nyob ntawm seb koj tus mob qog noj ntshav theem twg.

Cov kev kho mob rau qhov no yog dab tsi?

Kev kho mob rau fibrosarcoma nyob ntawm ntau yam, suav nrog koj txoj kev noj qab haus huv tag nrho, koj nyiam dab tsi, thiab hom mob qog noj ntshav.

Kev kho mob rau cov neeg laus fibrosarcoma

• Kev Phais Mob: Hauv txoj kev phais mob no, cov kws kho mob tshem tawm cov qog nqaij hlav thiab me ntsis cov nqaij mos noj qab nyob ib puag ncig nws kom paub tseeb tias tsis muaj cov qe ntshav qog nqaij hlav tshuav.
• Kev Kho Mob Hluav Taws Xob: Kev kho mob hluav taws xob yuav muab tau ua ntej phais kom lub qog me dua lossis rhuav tshem cov hlwb qog uas tseem tshuav tom qab phais.
• Kev Kho Mob Siv Tshuaj:Txawm hais tias muaj ib txhia kws kho mob sau ntawv kom siv txoj kev kho no los, nws tsis tau ua tiav zoo rau cov neeg laus uas mob fibrosarcoma. Hom mob qog noj ntshav no feem ntau tsis teb zoo rau kev kho mob chemotherapy.

Kev kho mob rau cov menyuam yaus fibrosarcoma

• Kev Phais Mob: Rau cov menyuam yaus, kev phais tshem tawm cov qog feem ntau tuaj yeem kho tau tus kab mob tag nrho.
• Kev siv tshuaj tua kab mob thiab/lossis tshuaj kho mob qog nqaij hlav: Cov kev kho mob no yog siv los ua kom cov qog nqaij hlav me me ua ntej phais lossis rhuav tshem cov hlwb uas tseem tshuav tom qab phais. Tsis zoo li cov neeg laus, feem ntau cov fibrosarcomas thaum yau teb tau zoo heev rau kev siv tshuaj kho mob qog nqaij hlav.
• Kev Kho Mob Rau Lub Hom Phiaj: Kev kho mob no tuaj yeem tiv thaiv cov cell kom tsis txhob faib sai vim muaj teeb meem nrog cov noob 'NTRK'. Qhov no tuaj yeem ua rau cov qog nqaij hlav me dua thiab ua rau kev phais yooj yim dua.

Tom qab kho mob tas, tus mob zoo li cas lawm? (Kev kwv yees)

Cov txiaj ntsig rau cov kab mob fibrosarcoma me nyuam yaus zoo heev. Feem ntau ntawm cov no tuaj yeem kho tau tag nrho los ntawm kev phais, kev siv hluav taws xob, tshuaj kho mob qog noj ntshav, lossis kev kho mob tsom rau cov neeg mob. Tus nqi ciaj sia nyob 10 xyoo yog li 90%. Yog tias kev phais tuaj yeem tshem tawm tag nrho cov cim ntawm tus mob qog noj ntshav, tus lej ntawd yuav luag 100%.

Cov mob fibrosarcoma uas pib thaum laus muaj teeb meem nyuaj dua. Cov qog no feem ntau raug kuaj pom tom qab lawv loj txaus los cuam tshuam rau cov hlab ntsha lossis cov ntshav ntws. Ib yam li lwm yam mob qog noj ntshav, kev kuaj pom thaum ntxov ua rau muaj txiaj ntsig zoo dua. Thaum mob qog noj ntshav tau nce mus rau theem siab, nws yuav nyuaj rau kho. Kwv yees li ib nrab ntawm cov neeg mob yuav rov qab muaj tus kab mob dua tom qab kho tas.

Yog koj muaj tus mob no, koj yuav saib xyuas koj tus kheej li cas?

Muaj coob tus neeg xav tias lawv tsis muaj zog thaum lawv raug kuaj pom tias muaj mob qog noj ntshav. Ib txoj hauv kev zoo tshaj plaws los daws cov kev xav no yog saib xyuas koj tus kheej thaum lub sijhawm kho mob thiab tom qab kho mob. Nov yog qee yam uas koj tuaj yeem ua tau:

• To taub koj txoj kev npaj ua raws li nram no: Nug koj tus kws kho mob seb yuav xav li cas thaum lub sijhawm rov zoo thiab thaum lub sijhawm teem tseg.
• Tswj Kev Ntxhov Siab: Kev mus kuaj mob tsis tu ncua tom qab kev kho mob yog qhov tseem ceeb rau kev kuaj pom thaum ntxov ntawm kev rov qab mob qog noj ntshav. Tab sis nws kuj tuaj yeem ua rau ntxhov siab. Tham nrog tus kws pab tswv yim txog qhov ntawd.
• Thov kev pab: Koj yuav tsum tau kev pab thaum lub sijhawm kho mob. Tej zaum cov neeg koj hlub yuav tos pab koj. Qhia rau lawv paub tias koj pab tau li cas.
• Ua tib zoo saib xyuas kev noj qab haus huv zoo: Kev noj zaub mov zoo, kev tawm dag zog txaus, thiab kev pw tsaug zog zoo yog qhov tseem ceeb heev.
• So kom txaus:Mob qog noj ntshav thiab kev kho mob qog noj ntshav tuaj yeem ua rau koj nkees heev. Npaj kom tau so kom ntau li ntau tau thaum lub sijhawm kho mob.
• Tawm tsam kev ntxhov siab: Tej yam xws li kev xav, kev tawm dag zog so kom txaus, thiab kev tawm dag zog ua pa tob tob tuaj yeem pab txo kev ntxhov siab.

Thaum twg koj yuav tsum mus ntsib kws kho mob?

Tom qab kho mob tas, feem ntau koj yuav mus ntsib koj tus kws kho mob txhua peb lub hlis rau ob xyoos thawj zaug thiab tom qab ntawd ntev dua me ntsis rau plaub txog tsib xyoos. Yog tias fibrosarcoma rov tshwm sim dua, uas feem ntau tshwm sim hauv tsib xyoos thawj zaug, lub sijhawm no yuav pab nrhiav pom qhov rov tshwm sim dua thaum ntxov.

Koj yuav tsum hu rau koj tus kws kho mob txhua lub sijhawm koj muaj pob tshiab lossis mob tshiab.

Thaum twg koj yuav tsum mus rau Chav Kho Mob Thaum Muaj Xwm Ceev (ETU)?

Ntau yam kev kho mob qog noj ntshav cuam tshuam rau koj lub cev tiv thaiv kab mob, uas ua rau koj muaj feem kis kab mob ntau dua. Nov yog qee cov tsos mob uas yuav xav kom koj mus rau Chav Kho Mob Thaum Muaj Xwm Ceev (ETU) thaum lub sijhawm kho mob:

• Kub taub hau txog 38.3 degrees Celsius (100.4 Fahrenheit) lossis siab dua.
• Hnov txias thiab tshee hnyo.
• Hnoos nrog cov hnoos qeev.
• Mob plab.
• Mob raws plab tas li.
• Xeev siab thiab ntuav tas li.