Koj puas tau muaj mob nraub qaum txij li thaum koj tseem hluas, lossis koj thawj zaug sawv ntxov hnov mob nraub qaum? Puas zoo li mob ploj mus tom qab taug kev luv luv lossis thaum koj pib ua haujlwm txhua hnub? Tej zaum koj yuav xav tias qhov no tsuas yog mob nraub qaum yooj yim xwb. Tab sis qee zaum cov tsos mob no tuaj yeem yog thawj cov cim ntawm tus mob hu ua Ankylosing Spondylitis, uas peb tab tom tham txog hnub no. Tsis txhob txhawj, peb yuav tham txog qhov no kom meej thiab yooj yim.
Ankylosing Spondylitis (AS) yog dab tsi tiag?
Hais yooj yim xwb, Ankylosing Spondylitis (AS) yog ib hom mob pob qij txha. Tab sis nws cuam tshuam rau cov pob qij txha hauv peb tus txha nqaj qaum . Peb tus txha nqaj qaum muaj ntau lub pob txha me me uas sib sau ua ke, thiab cov pob qij txha ntawm cov pob txha no yuav o, o, thiab mob. Raws li lub sijhawm dhau mus, qhov kev o no tuaj yeem ua rau cov pob qij txha hauv tus txha nqaj qaum sib koom ua ke, txo qhov kev ywj pheej ntawm tus txha nqaj qaum.
Cov tsos mob ntawm tus kab mob no yog:
- Mob nraub qaum thiab mob nqaij: Qhov no tshwj xeeb tshaj yog thaum koj sawv ntxov lossis tom qab sawv ntev.
- Txo qhov mob thaum lub sijhawm ua si: Qhov xav tsis thoob, qhov mob nce ntxiv thaum so thiab txo qis thaum ua ub ua no, xws li taug kev, khiav, lossis dhia.
- Mob hauv lwm cov pob qij txha: Qee tus neeg kuj tseem yuav mob hauv cov pob qij txha xws li lub duav, lub hauv caug, thiab pob luj taws.
- Xav tias nkees heev.
Kab mob no feem ntau pib rau cov tub ntxhais hluas hnub nyoog ntawm 15 thiab 30 xyoo. Yog vim li ntawd ntau tus neeg thiaj li yuam kev tias nws yog mob nraub qaum yooj yim.
Yog li ntawd puas muaj qhov txuas caj ces rau qhov no?
Yog. Qhov no yog qhov tseem ceeb tshaj plaws ntawm tsab xov xwm no. Ankylosing Spondylitis yog ib yam kab mob uas muaj los ntawm noob caj noob ces, uas yog, nws muaj feem cuam tshuam los ntawm noob caj noob ces . Yog tias ib tug neeg hauv koj tsev neeg, uas yog, niam txiv, cov kwv tij neej tsa, muaj tus kab mob no, ces koj kuj muaj feem yuav mob no ntau dua li lwm tus.
Thaum cov kws tshawb fawb tshawb nrhiav qhov no, lawv tau tsom ntsoov rau ib qho noob caj noob ces tshwj xeeb: lub noob caj noob ces HLA-B27 .
Xav txog seb, ntau tshaj 85% ntawm cov neeg mob uas kuaj pom tias muaj Ankylosing Spondylitis tau pom tias muaj cov noob caj noob ces no hu ua HLA-B27. Qhov ntawd puas qhia tau tias muaj kev sib txuas ntawm cov noob caj noob ces no thiab tus kab mob?
Cov noob caj noob ces HLA-B27 no pab peb lub cev tiv thaiv kab mob. Hais yooj yim xwb, nws paub thiab tawm tsam cov neeg txawv teb chaws xws li cov kab mob thiab cov kab mob me. Tab sis qee zaum, vim muaj kev hloov pauv hauv cov noob caj noob ces no, lub cev tiv thaiv kab mob tsis ua haujlwm thiab pib tawm tsam cov khoom noj qab haus huv ntawm peb lub cev, hauv qhov no, cov pob qij txha hauv peb tus txha nraub qaum. Cov kws tshawb fawb ntseeg tias qhov kev o no yog los ntawm qhov no.
Puas yog HLA-B27 tib leeg xwb uas muaj lub luag haujlwm rau qhov no?
Tsis yog. Lo lus nug ntawd tseem ceeb heev. Txawm hais tias HLA-B27 yog tus cwj pwm tseem ceeb hauv zaj dab neeg no, tseem muaj ob peb tus neeg ua yeeb yam txhawb nqa. Cov kws tshawb fawb hais tias kwv yees li 30% ntawm tag nrho cov kev pheej hmoo caj ces rau kev tsim tus kab mob no los ntawm HLA-B27 gene. Tus so yog cuam tshuam los ntawm ntau lwm cov gene me me.
Vim tias cov teebmeem ntawm cov noob caj noob ces no me me, nws nyuaj rau txheeb xyuas lawv ib qho zuj zus. Txawm li cas los xij, ntau cov noob caj noob ces tau raug txheeb xyuas los ntawm kev tshawb fawb uas cov kws tshawb fawb thoob ntiaj teb tau ua uas tau koom tes thiab sib qhia cov ntaub ntawv.
| Cov noob caj noob ces | Piav qhia yooj yim |
|---|---|
| HLA-B27 | Qhov no yog tus gene tseem ceeb. Nws muaj feem cuam tshuam nrog lub cev tiv thaiv kab mob. Feem ntau ntawm cov neeg mob AS muaj tus gene no. |
| ERAP1 | Qhov no kuj yog ib hom noob caj noob ces uas koom nrog kev ua haujlwm ntawm lub cev tiv thaiv kab mob. Nws ua rau muaj kev pheej hmoo ntawm kev muaj kab mob thaum muab sib xyaw nrog HLA-B27. |
| IL23R thiab IL1A | Cov no kuj yog cov noob caj noob ces uas koom nrog kev loj hlob thiab tswj kev o ntawm lub cev. Kev hloov pauv ntawm cov noob caj noob ces no kuj tuaj yeem ua rau muaj kev pheej hmoo ntawm AS. |
Cov kws tshawb nrhiav tseem tab tom nrhiav lwm cov noob caj noob ces uas tsis tau paub meej uas kuj yuav cuam tshuam rau qhov no.
Puas yog txhua tus neeg tau tus kab mob tsuas yog vim lawv muaj cov noob caj noob ces xwb?
Tsis yog. Yeej tsis yog.Qhov no yog ib yam uas koj yuav tsum nco ntsoov. Muaj cov noob caj noob ces HLA-B27 hauv koj lub cev tsis tau txhais hais tias koj yuav mob Ankylosing Spondylitis. Nws tsuas txhais tau hais tias koj muaj feem yuav mob ntau dua li lwm tus me ntsis xwb.
Xav txog nws li no. Ib txoj kev tshawb fawb pom tias 75% ntawm cov menyuam yaus uas tau txais cov noob caj noob ces HLA-B27 los ntawm niam txiv uas muaj Ankylosing Spondylitis, lossis peb ntawm plaub tus, yuav tsis muaj tus kab mob no li.
Qhov no txhais tau hais tias cov noob caj noob ces ib leeg tsis txaus los ua rau muaj tus kab mob no. Ntxiv rau cov kev cuam tshuam ntawm noob caj noob ces , cov yam ntxwv ib puag ncig kuj yuav tsum muaj. Txawm hais tias tseem tsis tau paub meej tias cov yam ntxwv no yog dab tsi, nws ntseeg tias qee yam, xws li qee yam kev kis kab mob, yuav ua lub luag haujlwm. Hais yooj yim, cov noob caj noob ces zoo li hmoov phom uas npaj txhij rau kev kub hnyiab, thiab nws xav tau lub hluav taws xob los kub hnyiab.
Yog li ntawd, kuv yuav tsum ua li cas?
Yog tias koj muaj cov tsos mob zoo li cov uas tau hais hauv tsab xov xwm no (mob nraub qaum uas pib thaum tseem hluas, mob hnyav dua thaum sawv ntxov, thiab mob tau zoo dua los ntawm kev tawm dag zog), lossis yog tias ib tug neeg hauv koj tsev neeg muaj Ankylosing Spondylitis, koj tsis tas yuav txhawj.
Qhov zoo tshaj plaws uas koj ua tau yog mus ntsib kws kho mob uas tsim nyog, koj tus kws kho mob GP, tam sim ntawd . Nws yuav mloog koj cov tsos mob, kuaj koj, thiab yog tias tsim nyog, xaj kev kuaj ntshav thiab X-rays. Lawv kuj tseem yuav pom zoo kom kuaj seb koj puas muaj HLA-B27 gene.
Nco ntsoov tias, qhov tseem ceeb tshaj plaws yog txheeb xyuas thiab tswj cov mob no thaum ntxov . Yog tias koj ua tau, koj tuaj yeem tswj tau qhov mob, tiv thaiv kev mob nraub qaum, thiab ua neej nyob zoo siab thiab zoo siab.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Ankylosing Spondylitis (AS) yog ib hom mob pob qij txha uas feem ntau cuam tshuam rau tus txha nraub qaum. Nws feem ntau tshwm sim rau cov tub ntxhais hluas.
- Tus kab mob no muaj kev sib txuas lus zoo heev nrog cov noob caj noob ces, tshwj xeeb tshaj yog cov noob HLA-B27 yog ib qho tseem ceeb.
- Txawm li cas los xij, tsuas yog muaj cov noob HLA-B27 hauv koj lub cev tsis tau txhais hais tias koj yuav muaj tus kab mob. Nws tsuas yog ib qho kev pheej hmoo xwb.
- Ntxiv rau cov noob caj noob ces (genes), cov yam ntxwv ib puag ncig kuj tseem cuam tshuam rau qhov tshwm sim ntawm tus kab mob no.
- Yog tias koj mob nraub qaum ntev, mob nqaij tawv thaum sawv ntxov, lossis muaj keeb kwm mob hauv tsev neeg, tsis txhob ntshai thiab sab laj nrog koj tus kws kho mob kom tau cov lus qhia zoo.
💬 Comments (0)
Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus