Koj puas feem ntau muaj kev ua xua nrog cov pob liab thiab khaus thoob plaws koj lub cev? Qhov no yuav yog Mastocytosis!

Koj puas feem ntau muaj pob liab, khaus, thiab qee zaum mob hnyav rau ntawm koj lub cev? Los yog koj puas raug kev tsis haum tshuaj hnyav rau txawm tias yog yam me me li ntau hnub? Tej zaum koj yuav xav tias, "Kuv muaj lwm yam kev tsis haum tshuaj." Txawm li cas los xij, qee zaum tom qab cov tsos mob no, tej zaum yuav muaj ib qho mob tsis tshua muaj uas peb tsis tau hnov ​​​​dua. Ib qho mob zoo li no yog '(Mastocytosis)'. Txawm hais tias lub npe yuav suab txawv me ntsis, cia peb tham txog nws yooj yim.

Mastocytosis yog dab tsi? Hais yooj yim xwb...

Xav txog seb, hauv peb lub cev muaj cov hlwb uas zoo li cov neeg zov me nyuam me. Peb hu lawv ua "mast cells." Cov "mast cells" no yog ib feem ntawm peb lub "tiv thaiv kab mob ." Lawv zoo li cov tub rog kev ruaj ntseg ntawm peb lub teb chaws. Thaum cov yeeb ncuab xws li cov kab mob, cov kab mob me me, thiab cov tshuaj ua xua nkag mus rau hauv lub cev, cov "mast cells" no tawm los thiab tawm tsam.

Thaum cov '(mast cells)' no teb rau cov yeeb ncuab, lawv tso tawm cov tshuaj hu ua '(histamine).' Cov '(histamine)' no yog qhov ua rau muaj cov tsos mob ua xua hauv peb lub cev (piv txwv li, khaus, liab ntawm daim tawv nqaij, o). Cov '(mast cells)' no kuj pab tsim cov kua qaub hauv plab.

Feem ntau, cov '(mast cells)' no ua lawv txoj haujlwm thiab tswj cov yeeb ncuab thiab tom qab ntawd rov qab ntsiag to dua. Txawm li cas los xij, qhov tshwm sim hauv lub cev ntawm tus neeg uas muaj '(Mastocytosis)' yog tias cov '(mast cells)' no nce ntxiv tsis zoo thiab tsis tuaj yeem tswj tau. Thaum lawv nce ntxiv zoo li no, cov cell no tso tawm ntau dhau '(histamine).' Qhov ntawd yog thaum koj ua xua loj rau txawm tias qhov me tshaj plaws, lossis thaum koj ua xua, nws phem dua li tus neeg ib txwm, thiab nws kav ntev dua.

Qhov tseem ceeb tshaj plaws, txhua tus neeg uas muaj Mastocytosis muaj feem yuav mob anaphylaxis , uas yog kev ua xua tam sim ntawd, hnyav, thiab muaj peev xwm ua rau tuag taus . Yog li ntawd, nws yog ib qho tseem ceeb uas yuav tsum paub txog qhov no.

Txawm hais tias cov kws kho mob tsis tuaj yeem kho tau Mastocytosis tag nrho, lawv tuaj yeem tswj cov tsos mob thiab kho txhua yam teeb meem uas yuav tshwm sim.

Cov hom mob Mastocytosis tseem ceeb yog dab tsi?

Muaj ob hom kab mob no tseem ceeb:

1. Mob Mastocytosis ntawm daim tawv nqaij: Qhov no feem ntau tshwm sim rau cov menyuam mos thiab cov menyuam yaus . Txawm li cas los xij, nws kuj tuaj yeem tshwm sim rau cov neeg laus. Qhov tshwm sim ntawm no yog tias cov "mast cells" tsis zoo sib sau ua ke hauv daim tawv nqaij, ua rau khaus liab, liab tsaus, xim av, lossis cov pob liab sib xyaw thiab cov pob. Nws zoo li ib tug menyuam yaus me me tam sim ntawd muaj ntau cov pob liab ntawm lawv lub cev thiab lawv khawb lawv tsis tu ncua.

2. Kev mob Mastocytosis hauv lub cev: Hom no feem ntau pom muaj rau cov neeg laus.Ntawm no, cov "mast cells" uas tsis zoo li qub sib sau ua ke hauv cov kabmob sab hauv xws li cov pob txha, cov pob txha, peb lub cev zom zaub mov, thiab cov ntsws. Xav txog seb, yog tias cov cell no sib sau ua ke ntau dhau hauv cov pob txha, nws tuaj yeem cuam tshuam rau kev tsim cov qe ntshav. Tsis tas li ntawd, yog tias cov cell no nce ntxiv hauv plab, lawv tuaj yeem tsim cov kua qaub hauv plab ntau dhau thiab ua rau mob plab.

Qhov no puas yog ib yam kab mob uas neeg feem ntau muaj?

Tsis yog, qhov no yog ib qho mob tsis tshua muaj. Raws li kev soj ntsuam, lawv hais tias tsuas yog ib tug ntawm kaum txhiab (10,000) lossis ib tug ntawm nees nkaum txhiab (20,000) tus neeg raug tus kab mob no. Yog li ntawd, nws yog ib qho ib txwm muaj uas tsis yog txhua tus paub txog nws.

Cov tsos mob ntawm Mastocytosis yog dab tsi?

Thaum cov "mast cells" no loj hlob tsis zoo li qub, muaj ntau yam tsos mob tshwm sim. Txawm hais tias cov tsos mob no yuav tsis hnyav heev rau qee tus neeg, tab sis lawv tuaj yeem hnyav rau lwm tus.

• Mob pob txha: Zoo li koj cov pob txha mob.
• Mob plab (mob plab): Yuav tsum mus chav dej ntau zaus.
• Tsaus muag (zoo li tsis nco qab): Tam sim ntawd, koj ob lub qhov muag tig xiav thiab koj zoo li tsis nco qab lawm.
• Ib qho xwm txheej ntxhov siab thiab ntshai tas li: Xav tias ntxhov siab yam tsis muaj laj thawj.
• Flushing: Tam sim ntawd daim tawv nqaij liab thoob plaws lub cev.
• Khaus khaus lossis pob ntawm daim tawv nqaij: Raws li peb tau tham txog ua ntej.
• Mob taub hau: Mob taub hau ntau zaus.
• Kab mob kiv taub hau los ntawm cov ntshav qis: Muaj kev xav tias kiv taub hau thaum sawv ntawm qhov chaw sawv ntsug.
• Mob pob qij txha: Mob pob qij txha.
• Cov pob liab los yog xim av ntawm daim tawv nqaij: Cov no tej zaum yuav khaus los yog tsis khaus.

Thaum muaj hnub nyoog li cas mastocytosis pib?

Nws txawv nyob ntawm hom kab mob. Feem ntau hais lus:

• Cutaneous Mastocytosis: Qhov no tuaj yeem cuam tshuam txawm tias cov menyuam mos.
• Mastocytosis hauv lub cev: Feem ntau cuam tshuam rau cov neeg laus hnub nyoog tshaj 50 xyoo.

Vim li cas ho ua li no?

`(Mastocytosis)` tsis yog ib yam dab tsi uas peb yug los nrog. Nws yog tshwm sim los ntawm kev hloov pauv hauv cov noob hu ua `(KIT noob)`. Cov `(KIT noob)` no yog cov noob uas pab qee hom cell, xws li peb cov cell ntshav, `(mast cell)`, loj hlob. Hauv `(Mastocytosis), cov `(KIT noob)` uas tau hloov pauv no muab cov cim tsis raug rau `(mast cell)` kom "loj hlob ntau dhau thiab loj hlob tsis tuaj yeem tswj tau."

Dab tsi yog cov ua rau mob mastocytosis?

Qhov no yuav txawv ntawm ib tus neeg mus rau ib tus neeg. Tsis yog txhua tus muaj tib yam ua rau mob. Txawm li cas los xij, muaj qee yam uas feem ntau tuaj yeem ua rau cov tsos mob ntau ntxiv:

• Txhuam los yog khawb daim tawv nqaij: Qhov no kuj tuaj yeem tshwm sim rau qee tus neeg tsuas yog hnav khaub ncaws nruj.
• Kev tawm dag zog thiab kev ua ub ua no ntau dhau.
• Kab tom los yog tom:Tshwj xeeb tshaj yog cov tsiaj xws li ntsaum, ntsaum me, thiab muv.
• Haus dej cawv.
• Tej yam khoom noj: Tshwj xeeb tshaj yog cov khoom noj ntsim, cov khoom noj uas muaj ntxhiab heev.
• Qee cov tshuaj: Piv txwv li, cov tshuaj tua kab mob hu ua "NSAIDs" (Cov tshuaj tsis yog steroidal anti-inflammatory), cov tshuaj ua kom cov leeg so, thiab cov tshuaj loog "(anesthesia)"
• Kev hloov pauv sai sai ntawm qhov kub thiab txias: Zoo li dhia mus rau hauv dej txias heev.
• Kev ntxhov siab ntawm lub cev lossis lub hlwb: Qhov no feem ntau muaj kev cuam tshuam loj heev.

Cov teeb meem uas yuav tshwm sim ntawm Mastocytosis yog dab tsi?

Tus kab mob no tuaj yeem ua rau muaj lwm yam teeb meem kev noj qab haus huv, suav nrog:

• Kab mob pob txha (Osteoporosis): Qhov no ua rau cov pob txha tsis muaj zog thiab yooj yim tawg.
• Teeb meem siab: Ib qho mob uas lub siab o thiab tsis ua haujlwm zoo.
• Cytopenia: Lub cev tsis muaj peev xwm tsim cov qe ntshav txaus.
• Kev kis kab mob ntau zaus.

Yuav kuaj mob Mastocytosis li cas?

Koj tus kws kho mob yuav nug txog koj cov tsos mob thiab kuaj koj daim tawv nqaij. Tsis tas li ntawd xwb, lawv yuav ua cov kev kuaj xws li:

• Kev kuaj ntshav: Xyuas seb koj cov ntshav muaj pes tsawg lub enzyme hu ua "tryptase". Lub "tryptase" no yog ib yam dab tsi uas "mast cells" tso tawm thaum lawv teb rau cov yeeb ncuab.
• Kev kuaj pob txha: Txhawm rau kuaj xyuas seb pob txha puas puas tsuaj.
• Kev kuaj mob pob txha: Yuav muab cov qauv pob txha coj mus kuaj thiab xyuas seb puas muaj cov hlwb mast cell txawv txav.
• Kev kuaj noob caj noob ces: Yog tias koj muaj Systemic Mastocytosis, koj tuaj yeem raug kuaj xyuas seb puas muaj kev hloov pauv hauv cov noob caj noob ces KIT.

Cov kev kho mob rau Mastocytosis yog dab tsi?

Cov kev xaiv kho mob sib txawv nyob ntawm hom kab mob thiab koj cov tsos mob. Cov kws kho mob feem ntau siv cov tshuaj thiab lwm yam kev kho mob los txo cov tsos mob.

Cov tshuaj siv rau Mastocytosis:

• Cov tshuaj Antacids rau cov teeb meem plab (Antacids - H2 blockers): Rau cov teeb meem xws li mob plab thiab mob plab hnyuv.
• Cov Tshuaj Antihistamines: Txo cov tsos mob ntawm daim tawv nqaij xws li khaus thiab liab.
• Bisphosphonates rau osteoporosis: Ua kom cov pob txha muaj zog.
• Cov tshuaj Corticosteroids: Txo qhov o.
• Cov tshuaj monoclonal antibodies: tshwj xeeb yog cov tshuaj xws li omalizumab (Xolair®).
• Tshuaj mob .

Lwm yam kev kho mob:

• Kev kho mob lub teeb ultraviolet (UV): Txo cov pob tsaus ntawm daim tawv nqaij.
• Kev kho mob tsom mus rau .
• Epinephrine rau anaphylaxis:Kev kho mob thaum muaj xwm txheej ceev rau kev ua xua hnyav.
• Kev kho mob qog noj ntshav: Qhov no tsis tshua muaj thiab tsuas yog muab yog tias Mastocytosis hloov mus ua mob qog noj ntshav.
• Kev hloov hlwb pob txha (allogeneic stem cell): Qhov no kuj raug txiav txim siab rau cov teeb meem loj heev thiab nyuaj ntawm mastocytosis. Feem ntau cov neeg tsis xav tau qhov no.

Puas muaj teeb meem lossis cov kev mob tshwm sim ntawm kev kho mob?

Yog, ib yam li kev kho mob twg los xij, muaj qee qhov kev mob tshwm sim uas tuaj yeem tshwm sim nrog kev kho mob rau Mastocytosis. Qee qhov yuav me me, thaum lwm tus yuav loj dua. Yog tias koj muaj Mastocytosis, koj tus kws kho mob yuav piav qhia txog kev kho mob uas koj tau txais thiab cov kev mob tshwm sim uas yuav tshwm sim.

Puas kho tau Mastocytosis kom zoo?

Feem ntau hais lus, Mastocytosis yog suav hais tias yog ib yam kab mob uas tsis tuaj yeem kho tau tag nrho, tab sis tuaj yeem tswj tau los ntawm kev tswj cov tsos mob thiab kho cov teeb meem .

Tib txoj kev kho mob uas yuav kho tau qhov teeb meem no yog "allogeneic stem cell (bone marrow) transplantation" uas tau hais ua ntej lawm. Txawm li cas los xij, txawm tias qhov ntawd tsuas yog pom zoo rau cov neeg mob uas muaj mob hnyav thiab nyuaj tshaj plaws xwb.

Puas yog Mastocytosis zuj zus tuaj raws sijhawm?

Yog tias tsis kho, cov tsos mob tuaj yeem hnyav zuj zus tuaj, tshwj xeeb tshaj yog rau ib tus neeg uas muaj mastocytosis hauv lub cev , vim tias cov hlwb mast cell tsis zoo tseem cuam tshuam rau cov pob txha thiab cov kabmob sab hauv.

Puas tiv thaiv tau tus kab mob Mastocytosis?

Tu siab kawg li, tsis yog. Vim tias nws yog los ntawm kev hloov pauv hauv cov noob caj noob ces KIT, tsis muaj txoj hauv kev los tiv thaiv nws. Txawm li cas los xij, yog tias koj muaj Mastocytosis, koj tuaj yeem tswj koj cov tsos mob los ntawm kev paub meej tias dab tsi ua rau koj ua xua thiab zam lawv ntau li ntau tau.

Piv txwv li, yog tias koj muaj ib yam tshuaj uas ua rau koj xav noj, nws yog ib lub tswv yim zoo kom hnav ib txoj hlua tes ceeb toom kev kho mob uas teev cov tshuaj ntawd. Qhov no yuav qhia rau lwm tus paub tias koj yuav tsum tsis txhob noj cov tshuaj twg yog tias muaj xwm txheej ceev.

Yog koj muaj tus kab mob Systemic Mastocytosis, nws yog ib qho tseem ceeb uas yuav tsum nqa ib lub koob txhaj tshuaj uas muaj epinephrine. Qhov no siv tau los kho cov kev ua xua hnyav, uas ua rau tuag taus xws li anaphylactic shock.

Kuv yuav saib xyuas kuv tus kheej li cas? (Mastocytosis) Thaum nyob nrog...

Vim tias Mastocytosis yog ib yam kab mob uas tsis tuaj yeem kho tau tag nrho, koj yuav tsum tau nyob nrog nws ib pliag. Nws tuaj yeem nyuaj. Txawm li cas los xij, ntawm no yog qee yam uas tuaj yeem pab koj:

• Paub meej tias yog dab tsi ua rau koj cov tsos mob tshwm sim.Txhua tus neeg muaj tej yam ua rau mob sib txawv. Tej zaum koj yuav xav sau ib phau ntawv sau txog koj tus kheej thiab sau thaum twg koj cov tsos mob hnyav zuj zus, koj noj dab tsi thiab haus dab tsi, thiab koj ua dab tsi thaum ntawd.
• Kev ntxhov siab ua rau cov tsos mob no hnyav zuj zus. Yog tias koj xav tau kev pab tswj kev ntxhov siab, nug koj tus kws kho mob txog cov kev pab cuam tswj kev ntxhov siab. Tej yam xws li kev xav thiab kev ua yoga yuav pab tau.
• Hnav ib txoj hlua tes ceeb toom txog kev kho mob. Nws yuav tsum teev koj tus mob thiab cov tshuaj uas koj tsis tas yuav noj.
• Nqa ib rab koob txhaj tshuaj epinephrine nrog koj tas li. Nws tuaj yeem cawm tau txoj sia yog tias muaj kev tsis haum tshuaj hnyav.

Kuv yuav tsum mus ntsib kuv tus kws kho mob thaum twg?

Koj yuav tsum mus ntsib koj tus kws kho mob tsis tu ncua . Lawv yuav saib xyuas koj cov tsos mob thiab hloov koj txoj kev kho mob yog tias tsim nyog. Yog tias koj muaj cov tsos mob tshiab, lossis yog tias koj cov tsos mob hnyav zuj zus, qhia rau koj tus kws kho mob tam sim ntawd.

Kuv yuav tsum mus rau Chav Xwm Ceev thaum twg?

Yog koj muaj kev tsis haum tshuaj hnyav heev uas tsis tuaj yeem tswj tau nrog tshuaj, mus rau chav kho mob ceev tam sim ntawd. Yog li ntawd, yog tias koj muaj cov tsos mob xws li ua pa nyuaj, caj pas nruj, kiv taub hau hnyav, lossis tsis nco qab.

Kuv yuav tsum nug kuv tus kws kho mob li cas?

Yog tias koj muaj Mastocytosis, nws yog ib lub tswv yim zoo los nug koj tus kws kho mob cov lus nug zoo li no:

• Kuv muaj hom Mastocytosis twg?
• Muaj kev kho mob dab tsi rau hom mob uas kuv muaj?
• Kev kho mob puas yuav tshem tawm kuv cov tsos mob tag nrho?
• Cov tsos mob ntxiv twg yuav qhia tau tias kuv tus mob hnyav zuj zus tuaj?
• Kuv puas yuav tau kho mob mus ib txhis?
• Yog tias kuv muaj daim ntawv hnyav dua, kuv qhov kev kwv yees yuav ua li cas?
• Puas muaj kev sim tshuaj uas kuv tuaj yeem koom nrog?

Thaum kawg, yuav tsum nco ntsoov li cas (Cov Lus Coj Mus Tsev)

Mastocytosis yog ib yam mob tsis tshua muaj uas ua rau muaj kev loj hlob tsis zoo thiab tsis tswj tau ntawm cov hlwb mast hauv lub cev. Nws tuaj yeem cuam tshuam rau daim tawv nqaij thiab cov kabmob sab hauv. Cov neeg feem coob tuaj yeem tswj lawv cov tsos mob los ntawm kev txheeb xyuas thiab zam cov teeb meem ua rau muaj kev tsis haum tshuaj thiab noj tshuaj. Nws tseem ceeb heev uas yuav tsum khaws cov tshuaj epinephrine txhaj rau ntawm tes kom kho cov kev tsis haum tshuaj hnyav.

Txawm hais tias qhov no yog ib yam kab mob uas tsis tuaj yeem kho tau tag nrho, nrog kev qhia thiab kev kho mob kom zoo, koj tuaj yeem sim tswj cov tsos mob thiab ua neej nyob li qub. Yog tias koj muaj lus nug ntxiv txog qhov no, tsis txhob yig nrog koj tus kws kho mob tham. Lawv yuav pab koj.

Mastocytosis , mast cells, histamine, allergy, kab mob ntawm daim tawv nqaij, lub cev tiv thaiv kab mob, anaphylaxis