Koj ob txhais ceg puas o thiab daim tawv nqaij puas ntxhib? Cia peb kawm txog qhov no (Pretibial Myxedema)!

Koj puas tau pom tias daim tawv nqaij ntawm koj ob txhais ceg, tshwj xeeb tshaj yog hauv qab lub hauv caug, cia li o, tuab, thiab qee zaum hloov xim? Los yog nws zoo li daim tawv txiv kab ntxwv hauv qee qhov chaw? Yog tias koj muaj cov tsos mob no, tej zaum koj muaj tus mob hu ua Pretibial Myxedema, uas peb yuav tham txog hnub no.

Qhov no (Pretibial Myxedema) yog dab tsi? Cia peb nkag siab yooj yim!

Hais yooj yim xwb, Pretibial Myxedema, qee zaum hu ua Graves' Dermopathy, yog ib hom kab mob Graves', uas yog ib yam mob uas cuam tshuam rau peb daim tawv nqaij. Nws yog tshwm sim los ntawm kev sib sau ua ke ntawm cov carbohydrates thiab suab thaj, lossis ntau dua, glycosaminoglycans lossis mucopolysaccharides, nyob rau hauv cov txheej tob dua ntawm peb daim tawv nqaij. Cov no feem ntau sib sau ua ke hauv qab ob txhais ceg, hauv qab lub hauv caug. Qhov no yog thaum ob txhais ceg o, daim tawv nqaij ua pob, thiab daim tawv nqaij ua pob khaus (scaling plaques). Cov lus "Pretibial" thiab "Myxedema" txhais li cas?

• "Pretibial": Qhov no yog hais txog pob txha loj nyob rau sab ntawm peb ceg hauv qab lub hauv caug, pem hauv ntej ntawm '(tibia)'. Yog tias peb hais nws hauv Sinhala, nws zoo li "nyob rau pem hauv ntej ntawm pob txha ncej puab".
• "Myxedema": Qhov no txhais tau tias o ntawm cov nqaij hauv qab peb daim tawv nqaij.

Leej twg raug kev cuam tshuam ntau tshaj plaws los ntawm qhov xwm txheej no?

(Pretibial Myxedema) Txawm hais tias leej twg los yeej muaj tau tus mob no, tab sis qee tus neeg yuav muaj feem ntau dua. Lawv yog:

• Cov neeg uas muaj tus kab mob Graves: Qhov no yog qhov teeb meem tseem ceeb.
• Cov neeg uas muaj teeb meem thyroid: Qhov no txhais tau tias cov mob xws li '(Hypothyroidism)' (cov thyroid hormone qis) lossis '( Hyperthyroidism )' ( cov thyroid hormone siab).
• Cov neeg uas muaj kab mob qhov muag hnyav: Qhov no feem ntau kuj cuam tshuam nrog Graves' Disease.
• Cov neeg hnub nyoog ntawm 40 thiab 60 xyoo.
• Cov Poj Niam: Tus mob no feem ntau tshwm sim rau cov poj niam dua li cov txiv neej.

Xav txog seb, koj tus neeg zej zog, Phauj Susila, tau muaj teeb meem thyroid tau ib ntus. Mam li nco dheev, nws pom tias thaj tsam hauv qab nws ob txhais ceg o, daim tawv nqaij liab me ntsis, thiab nws zoo li pob me me thaum kov. Thaum xub thawj, nws xav tias tej zaum yog vim nws siv zog ua haujlwm. Tab sis tsuas yog thaum nws qhia rau kws kho mob xwb nws thiaj paub tias tej zaum yog Pretibial Myxedema.

Cov hom mob Pretibial Myxedema tseem ceeb yog dab tsi?

Muaj plaub hom mob no tseem ceeb. Cov tsos mob yuav txawv me ntsis raws li: 1. Diffuse: Qhov no yog hom mob uas pom ntau tshaj plaws. Qhov no yog tus yam ntxwv los ntawm oedema uas tsis muaj qhov thiab tsis loj thaum daim tawv nqaij raug nias rau ntawm daim tawv nqaij. 2. Plaque:Ntxiv rau qhov o, muaj cov plaques tuab, tsa, thiab tawv ntawm qhov chaw ntawm daim tawv nqaij. 3. Nodular: Ntxiv rau qhov o, muaj cov nodules tawv hauv qab daim tawv nqaij. 4. Elephantiasis: Qhov no yog hom tsawg tshaj plaws. Hauv hom no, cov kua lymphatic sib sau ua ke hauv qab daim tawv nqaij, ua rau daim tawv nqaij zoo li pob khaus, ntxhib.

Cov tsos mob ntawm (Pretibial Myxedema) yog dab tsi? Cia peb kawm paub lawv kom meej!

Yog koj muaj tus mob no, koj yuav muaj ib lossis ntau yam ntawm cov tsos mob no:

• O: Daim tawv nqaij ntawm koj txhais ceg zoo li loj dua thiab o dua li hnub ua ntej.
• Cov pob tawv tawv hauv qab daim tawv nqaij: Cov no tuaj yeem hnov ​​​​​​thaum koj kov lawv nrog koj txhais tes.
• Qee qhov chaw ntawm daim tawv nqaij ua tuab thiab zoo li cov plaques: zoo li cov nplai ntses.
• Cov tawv nqaij thiab cov plaub hau follicles yuav ci ntsa iab, zoo li roj nplaum: Nws yuav zoo li daim tawv txiv kab ntxwv .
• Cov xim ntawm daim tawv nqaij hloov pauv: nws tuaj yeem yog los ntawm daj thiab txiv kab ntxwv mus rau xim av, liab, thiab ntshav.
• Muaj kev tawm hws ntau ntxiv lossis cov plaub hau loj hlob ntau dhau ntawm cov cheeb tsam uas raug mob.
• Daim tawv nqaij mob los yog khaus.

Thaum xub thawj, tus mob no yuav pib ua ib lub pob tawv tawv rau ntawm daim tawv nqaij. Lub pob no yuav loj zuj zus, lossis yuav sib xyaw nrog lwm lub pob.

Cov tsos mob no cuam tshuam rau qhov twg ntawm lub cev tshaj plaws?

Cov tsos mob feem ntau ntawm Pretibial Myxedema yog:

• Ntawm ob txhais ceg hauv qab lub hauv caug.
• Nyob rau ntawm lub hauv paus ntawm ko taw.
• Cov ceg nyob rau hauv thaj tsam ceg.

Qee zaum kev hloov pauv ntawm lub ntsej muag tuaj yeem yog los ntawm Graves' Kab Mob lossis tus mob thyroid, tab sis qhov ntawd yog qhov teeb meem sib cais.

Vim li cas peb thiaj li muaj mob Pretibial Myxedema? Dab tsi yog cov ua rau muaj?

Txawm hais tias qhov ua rau qhov no tseem tsis tau nkag siab tag nrho, muaj ntau yam tau tshwm sim los ntawm kev tshawb fawb. Qhov laj thawj tseem ceeb rau qhov no yog kev sib sau ua ke ntawm cov suab thaj '(glycosaminoglycans lossis mucopolysaccharides)' uas peb tau hais ua ntej hauv '(dermis)' thiab '(hypodermis)' txheej ntawm daim tawv nqaij. Tab sis vim li cas nws thiaj sib sau ua ke li ntawd? 1. Ib qho txheej txheem tiv thaiv kab mob '(Autoimmune response)': Hais yooj yim, peb lub cev tus kheej tiv thaiv kab mob pib ua haujlwm tawm tsam peb. Hauv qhov no, peb lub cev tiv thaiv kab mob qhia peb cov hlwb kom tsim '(antibodies)' tawm tsam cov tshuaj hormones thyroid. Cov '(antibodies)' no ua rau cov hlwb tsim cov tshuaj hu ua '(glycosaminoglycans)' ntau dhau. 2. Kev ua haujlwm ntawm (T lymphocyte) hlwb: '(T lymphocytes)' yog ib hom hlwb tshwj xeeb hauv peb lub cev tiv thaiv kab mob. Cov hlwb no mus rau hauv cov ntaub so ntswg ntawm daim tawv nqaij thiab tso cov protein xa xov hu ua '(cytokines)'. Cov cytokines no ua rau cov hlwb tsim cov glycosaminoglycans ntau dhau. 3. Kev raug mob teb:Xav txog koj raug mob rau koj ceg qis, nyob rau hauv thaj tsam pretibial. Yog tias koj muaj hypothyroidism, cov hlwb tiv thaiv kab mob thiab cov protein tuaj yeem sib sau ua ke ntawm qhov chaw raug mob. Qhov no yog vim cov tshuaj hormones thyroid tswj cov khoom sib sau ua ke ntawm cov tshuaj no hauv cov nqaij. Thaum tsis muaj cov tshuaj hormones, qhov kev tswj hwm ntawd ploj mus.

Tus kws kho mob kuaj mob Pretibial Myxedema li cas?

Thaum koj mus ntsib kws kho mob, nws yuav nug koj txog koj cov tsos mob thiab lwm yam mob uas koj muaj ('(keeb kwm kho mob)'). Tom qab ntawd lawv yuav kuaj koj ('(kev kuaj lub cev)'). Txhawm rau kom paub tseeb tias qhov no puas yog (Pretibial Myxedema), kws kho mob yuav ua cov kev kuaj mob hauv qab no:

• Kuaj ntshav: Xyuas koj cov qib hormone thyroid .
• Kev kuaj tawv nqaij: Qhov no siv tau los txiav txim seb puas muaj tus mob thiab ntsuas cov glycosaminoglycans hauv daim tawv nqaij.

Puas muaj kev kho rau qhov no? Yuav ua li cas tau?

Feem ntau, cov tsos mob ntawm Pretibial Myxedema tsuas yog kho kom zoo nkauj xwb, yog li kev kho mob tsis tas yuav tsum tau kho tas li. Qhov ntawd yog, feem ntau lawv tsis ua rau muaj kev puas tsuaj loj . Txawm li cas los xij, yog tias koj tsis xis nyob nrog qhov tsos lossis muaj lwm yam tsos mob (khaus, mob), muaj kev kho mob.

• Hnav cov thom khwm nruj lossis cov thom khwm ntev: Qhov no tuaj yeem txo qhov o.
• Cov tshuaj pleev lossis tshuaj pleev rau sab nraud: Tiv thaiv kev khaus thiab o.
• Cov tshuaj noj thiab tshuaj pleev thiab tshuaj txhaj: Txhawm rau txo cov qog hauv qab daim tawv nqaij lossis txo qhov kev hloov pauv ntawm qhov tsos.
• Kev Kho Mob Graves' Kab Mob lossis Mob Thyroid: Qhov no yog qhov tseem ceeb tshaj plaws . Thaum kho qhov ua rau mob, cov tsos mob ntawm Pretibial Myxedema feem ntau zoo dua.
• Kev siv plasmapheresis: Qhov no yog ib txoj kev kho mob uas nyuaj me ntsis. Nws yog kev tshem tawm cov kua ntawm cov ntshav (plasma), hloov cov qe ntshav liab thiab cov qe ntshav dawb thiab cov platelets rau hauv cov kua tshiab, thiab tom qab ntawd rov qab coj lawv rov qab rau hauv lub cev. Qhov no tsis yog ib yam dab tsi uas txhua tus tuaj yeem ua tau.

Tseem Ceeb: Txawm hais tias kev phais mob tuaj yeem tshem tawm cov pob me me hauv qab daim tawv nqaij, feem ntau tsis pom zoo. Qhov no yog vim tias, thaum daim tawv nqaij kho tom qab phais mob, cov pob me me yuav rov tshwm sim dua ntawm qhov chaw raug mob. Qhov no yog vim tias lub cev kho qhov chaw phais mob zoo li "qhov txhab."

Cov tshuaj twg muab rau Pretibial Myxedema?

Koj tus kws kho mob yuav muab cov tshuaj rau koj xws li cov no los pab txo cov tsos mob ntawm tus mob no:

• (Cov tshuaj Corticosteroids):Cov no yog cov tshuaj pleev rau sab nraud uas pab txo qhov o, o, thiab khaus.
• (Pentoxifylline): Qhov no yog ib yam tshuaj noj uas pab kom cov ntshav ncig hauv ob txhais ceg zoo dua.
• (Octreotide): Qhov no yog ib qho tshuaj txhaj. Nws tuaj yeem txo qhov loj ntawm cov qog hauv qab daim tawv nqaij.
• (Rituximab): Qhov no kuj yog kev txhaj tshuaj rau hauv cov hlab ntsha. Nws pab peb lub cev cov tshuaj tua kab mob ua haujlwm kom zoo.
• Tshuaj immunoglobulin txhaj rau hauv cov hlab ntsha (IVIG): Qhov no kuj yog ib yam tshuaj uas muab rau hauv cov hlab ntsha. Nws ua kom cov tshuaj tua kab mob hauv lub cev tiv thaiv kab mob ua haujlwm tau zoo dua.

Ua ntej pib siv tshuaj tshiab, nco ntsoov nrog koj tus kws kho mob tham txog nws cov kev mob tshwm sim, koj yuav tsum noj ntev npaum li cas, thiab seb nws puas yuav ua teeb meem nrog lwm cov tshuaj uas koj tab tom noj.

Kuv yuav zoo sai npaum li cas tom qab kho tas?

Lub sijhawm ntev npaum li cas koj muaj cov tsos mob ntawm Pretibial Myxedema yuav txawv nyob ntawm seb koj tus mob hnyav npaum li cas. Yog tias kho, cov tsos mob yuav zoo dua li ob peb lub lis piam mus rau ob peb lub hlis. Yog tsis kho, qee zaum nws yuav siv sijhawm ntau xyoo rau qhov mob kom ploj mus. Tab sis nco ntsoov, yog tias koj raug mob rau koj ob txhais ceg qis, qhov mob tuaj yeem rov tshwm sim dua.

Puas muaj txoj hauv kev los tiv thaiv qhov no (Pretibial Myxedema) kom tsis txhob tshwm sim?

Tsis muaj ib txoj kev twg los tiv thaiv qhov no kom tsis txhob tshwm sim tag nrho, tab sis koj tuaj yeem ua cov hauv qab no kom txo koj qhov kev pheej hmoo:

• Tsis txhob siv cov khoom haus luam yeeb.
• Yog tias koj muaj cov mob uas cuam tshuam rau koj txoj kev ua haujlwm ntawm cov thyroid, nrhiav kev kho kom zoo.
• Hnav cov thom khwm nruj lossis cov thom khwm rau ntawm koj ob txhais ceg.

Yog tias kuv kuj muaj tus mob no thiab, puas yog ib yam uas yuav tsum ntshai?

Feem ntau cov neeg uas muaj tus kab mob Pretibial Myxedema yeej paub tias lawv yuav zoo. Yog tias koj cov tsos mob tsuas yog cuam tshuam rau koj qhov tsos xwb, tej zaum koj yuav tsis tas yuav kho mob. Yog tias koj muaj mob me me xwb, feem ntau nws yuav ploj mus nws tus kheej. Yog tias koj mob hnyav dua, qhov kev kwv yees yuav zoo, tab sis nws yuav siv sijhawm ntau xyoo los kho kom zoo.

Kuv puas yuav tsum tau mus ntsib kws kho mob?

Kab mob Pretibial Myxedema tuaj yeem rov qab tshwm sim txawm tias nws tau zoo lawm los xij, tshwj xeeb tshaj yog tias koj raug mob rau koj ceg qis. Yog li, yog tias koj cov tsos mob tau ploj mus thiab rov tshwm sim dua, tham nrog koj tus kws kho mob. Tsis tas li ntawd, yog tias koj muaj mob lossis khaus heev, nco ntsoov mus ntsib kws kho mob.

Kuv yuav tsum nug tus kws kho mob li cas?

Nws yog ib lub tswv yim zoo kom npaj qee cov lus nug zoo li no thaum koj mus ntsib kws kho mob:

• Kuv puas siv tau cov thom khwm compression los pab kho Pretibial Myxedema?
• Kuv puas xav tau kev kho mob rau Pretibial Myxedema?
• Puas yog kuv cov tsos mob yog los ntawm tus mob thyroid?
• Kuv yuav saib xyuas kuv daim tawv nqaij uas raug cuam tshuam los ntawm Pretibial Myxedema li cas?

Qhov txawv ntawm (Pretibial Myxedema) thiab (Erythema Nodosum) yog dab tsi?

Ob yam mob no cuam tshuam rau peb daim tawv nqaij, tshwj xeeb tshaj yog daim tawv nqaij ntawm peb ob txhais ceg hauv qab lub hauv caug. Txawm li cas los xij, muaj qhov sib txawv ntawm cov tsos mob:

• (Pretibial Myxedema): Qhov no ua rau o thiab ci ntsa iab, tuab, zoo li cov pob txha coral.
• (Erythema Nodosum): Qhov no ua rau o thiab me me, mob pob ntawm daim tawv nqaij.

Thaum kawg, tej yam uas yuav tsum nco ntsoov

Pretibial Myxedema yog ib yam mob uas feem ntau tsis tas yuav kho. Feem ntau, nws yuav ploj mus nws tus kheej. Txawm li cas los xij, yog tias qhov kev hloov pauv ntawm qhov tsos mob ua rau koj ntxhov siab, muaj kev kho mob. Kev hnav thom khwm nruj tuaj yeem pab txo qhov o thiab ua rau koj xis nyob dua. Yog tias koj muaj mob lossis khaus heev rau hauv koj ob txhais ceg qis, nco ntsoov tham nrog kws kho mob. Tsis tas li ntawd, qhov mob no feem ntau cuam tshuam nrog Graves' Kab Mob thiab teeb meem thyroid, yog li nws tseem ceeb heev uas yuav tsum paub txog cov ntawd thiab.

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