Koj thiab koj cov txheeb ze muaj ntau yam zoo sib xws, puas yog? Qhov muag xiav, qhov siab, thiab cov kab mob xws li mob hawb pob thiab mob plawv tuaj yeem kis tau los ntawm ntau tiam neeg. Yog li ntawd, yog tias koj muaj tus kab mob ntshav qab zib hom 1, tej zaum koj yuav xav tias, "Qhov no puas yog ib yam dab tsi uas kuv tau txais los ntawm niam txiv?" Thiab koj yuav txhawj me ntsis tias koj cov menyuam kuj yuav kis tau tus kab mob no. Nws yog ib qho tseem ceeb uas yuav tsum paub txog qhov no.
Ua ntej, cia peb nkag siab tias tus kab mob ntshav qab zib hom 1 yog dab tsi?
Hais yooj yim xwb, tus kab mob ntshav qab zib hom 1 yog ib yam kab mob autoimmune . Txiv, qhov ntawd puas zoo li nyuaj me ntsis? Okay, cia kuv piav qhia yooj yim xwb. Xav txog tias muaj ib pab tub rog los tiv thaiv peb lub teb chaws. Lub luag haujlwm ntawm pab tub rog ntawd tsuas yog tiv thaiv lub teb chaws ntawm cov yeeb ncuab sab nraud. Peb lub cev kuj muaj ib lub cev tiv thaiv zoo sib xws. Peb hu nws ua lub cev tiv thaiv kab mob . Nws txoj haujlwm yog txheeb xyuas thiab rhuav tshem cov yeeb ncuab sab nraud xws li cov kab mob, cov kab mob, thiab cov kab mob uas ua rau muaj kab mob thiab ua rau peb noj qab nyob zoo.
Txawm li cas los xij, nyob rau hauv tus kab mob autoimmune no, peb tus kheej lub cev tiv thaiv kab mob mus me ntsis 'yuam kev' thiab tsis tuaj yeem paub qhov txawv ntawm peb cov hlwb zoo thiab cov yeeb ncuab txawv teb chaws. Nws zoo li peb cov tub rog tawm tsam cov neeg tsis muaj txim hauv peb lub tebchaws.
Hauv hom ntshav qab zib hom 1, lub cev tiv thaiv kab mob no yuam kev tawm tsam ib hom cell tshwj xeeb hauv peb lub txiav hu ua beta cells . Cov beta cells no yog cov uas ua cov tshuaj insulin, uas yog qhov tseem ceeb rau peb lub cev. Insulin yog qhov uas coj cov suab thaj (glucose) los ntawm cov khoom noj uas peb noj thiab xa mus rau hauv cov cell kom hloov mus ua lub zog. Yog li thaum lub cev tiv thaiv kab mob rhuav tshem cov beta cells no, kev tsim insulin nres kiag li. Thaum ntawd yog thaum ntshav qab zib hom 1 tshwm sim.
Yog li ntawd, tiam neeg muaj feem cuam tshuam li cas rau qhov no?
Yog, tus kab mob ntshav qab zib hom 1 muaj nyob hauv tsev neeg. Qhov ntawd txhais tau tias muaj qee qhov kev sib txuas ntawm caj ces. Yog tias koj niam, txiv, kwv tij, muam, lossis tus menyuam muaj tus kab mob ntshav qab zib hom 1, koj muaj feem yuav mob li ntawm 15 npaug ntau dua li ib tus neeg uas tsis muaj tsev neeg uas muaj.
Tiam sis nco ntsoov qhov no: Tsis txhob ntshai thaum koj hnov qhov no. Tsuas yog vim koj muaj feem yuav kis tus kab mob 15 npaug ntau dua tsis tau txhais hais tias koj yuav kis tau tus kab mob ntawd.
Qhov xav tsis thoob yog, 85% ntawm cov neeg uas muaj tus kab mob ntshav qab zib hom 1, lossis ntau dua yim ntawm kaum tus neeg, tsis muaj keeb kwm tsev neeg muaj tus kab mob no . Tsis tas li ntawd, txawm tias ib tug neeg hauv tsev neeg muaj tus kab mob no los xij, qhov uas lwm tus yuav muaj tus kab mob no kuj tsawg heev.
Yog li qhov no tshwm sim li cas? Puas yog nws tsuas yog los ntawm noob caj noob ces xwb?
Tsis yog. Qhov tseem ceeb yog, cov noob caj noob ces xwb tsis yog qhov ua rau muaj qhov teeb meem no.Xav txog cov noob caj noob ces zoo li ib pawg hmoov phom uas npaj txhij yuav raug hluav taws. Tab sis kom nws hluav taws, nws xav tau lub hluav taws xob sab nraud. Lub hluav taws xob ntawd yog qhov peb hu ua 'cov yam ntxwv ib puag ncig' .
Cov kws kho mob thiab cov kws tshawb fawb tseem tab tom sim nrhiav seb qhov 'hluav taws' no yog dab tsi. Nws yuav yog kev kis kab mob los ntawm cov kab mob, ib yam dab tsi hauv cov khoom noj uas peb noj, lossis lwm yam ib puag ncig. Yog li, rau ib tus neeg kom muaj tus kab mob ntshav qab zib hom 1, lawv yuav tsum muaj cov noob caj noob ces uas ua rau lawv muaj tus kab mob, thiab lawv yuav tsum raug rau ib qho ib puag ncig uas ua rau cov noob caj noob ces ntawd. Thaum ob yam no los ua ke, lub cev tiv thaiv kab mob yuav tsis ua haujlwm thiab pib tawm tsam cov beta cell.
Cov noob caj noob ces twg cuam tshuam nrog tus kab mob ntshav qab zib hom 1?
Cov kws tshawb fawb tab tom ua ntau yam kev tshawb fawb txog kev hloov pauv caj ces uas cuam tshuam nrog tus kab mob ntshav qab zib hom 1. Ntau yam ntawm cov noob caj ces no cuam tshuam rau txoj kev uas peb lub cev tiv thaiv kab mob ua haujlwm. Ib qho tseem ceeb tshaj plaws ntawm cov no yog cov noob caj ces HLA (Human Leukocyte Antigen) . Cov noob caj ces HLA no yog cov uas qhia lub cev tiv thaiv kab mob kom paub qhov txawv ntawm "peb cov hlwb thiab cov hlwb txawv teb chaws." Yog li ntawd, yog tias muaj qhov tsis zoo hauv cov noob caj ces HLA no, lub cev tiv thaiv kab mob yuav tsis tuaj yeem ua qhov txawv no kom raug.
Cov noob caj noob ces HLA no kuj muab faib ua ntau hom sib txawv. Koj tuaj yeem tau txais lub tswv yim yooj yim ntawm qhov no los ntawm lub rooj hauv qab no.
| Kev Hloov Pauv ntawm Gene | Kev Cuam Tshuam rau Kab Mob Ntshav Qab Zib Hom 1 |
|---|---|
| HLA-DR2 | Nws zoo li tiv thaiv tau tus kab mob ntshav qab zib hom 1 rau qee qhov. |
| HLA-DR3 los yog HLA-DR4 | Kab mob ntshav qab zib hom 1 ua rau muaj kev pheej hmoo ntau ntxiv . Nws yog qhov tshwj xeeb tshaj yog rau cov neeg dawb. |
| HLA-DR7 | Cov neeg dub tau raug txheeb xyuas tias muaj kev pheej hmoo ntau dua . |
| HLA-DR9 | Nws tau raug txheeb xyuas tias yog qhov ua rau muaj kev pheej hmoo ntxiv rau cov neeg Nyiv Pooj. |
Tsis tas li ntawd xwb, qee qhov kev hloov pauv hauv INS gene, uas qhia lub cev kom tsim cov insulin, kuj tseem yuav muaj feem cuam tshuam nrog ntshav qab zib hom 1.
Cov kev kuaj noob caj noob ces no feem ntau yog ua nyob rau theem kev tshawb fawb. Yog tias koj xav paub ntxiv txog qhov no lossis muaj kev txhawj xeeb txog koj keeb kwm tsev neeg, nws yog qhov zoo tshaj plaws los tham nrog koj tus kws kho mob txog qhov no.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Kab mob ntshav qab zib hom 1 yog ib yam kab mob uas tshwm sim los ntawm qhov tsis zoo ntawm lub cev tiv thaiv kab mob (kab mob autoimmune), es tsis yog los ntawm noob caj noob ces.
- Txawm hais tias muaj ib tug neeg hauv tsev neeg uas muaj tus kab mob ntshav qab zib hom 1 ua rau koj muaj feem yuav mob ntau ntxiv, nws tsis tau txhais hais tias koj lossis koj tus menyuam yuav mob.
- Feem ntau cov neeg uas muaj tus kab mob ntshav qab zib hom 1 (kwv yees li 85%) tsis muaj keeb kwm tsev neeg ntawm tus kab mob no.
- Ob qho tib si yuav tsum muaj kev mob caj ces thiab ib puag ncig uas ua rau muaj tus kab mob no.
- Yog koj muaj kev txhawj xeeb lossis kev tsis ntseeg txog keeb kwm mob ntshav qab zib hauv koj tsev neeg lossis koj tus menyuam txoj kev pheej hmoo, nrog koj tus kws kho mob tham txog qhov ntawd thiab tau txais cov lus qhia kom raug.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus