Sɔntɛnde, wi kin fil bad, wɔri, ɛn wi nɔ kin ebul fɔ du ɛnitin, dat kin mek wi nɔ ebul fɔ ivin du di wok dɛn we wi kin du ɛvride. Dɛn kayn tɛm ya, we yu go to dɔktɔ, i kin no se yu gɛt pwɛl hat ɛn tɛl yu fɔ gi yu tritmɛnt. Desipramine na wan mɛrɛsin wae dɛn kin yuse bɔrku tɛm fɔ mɛn pwɛl hat. So if dɛn dɔn gi yu ɔ pɔsin we de nia yu dis mɛrɛsin, i impɔtant fɔ no bɔt am.
Wetin na Desipramine?
Fɔ tɔk am simpul wan, Desipramine na mɛrɛsin wae dɛn kin yuse fɔ mɛn pwɛl hat. Na wi bren kin mek kemikal mɛsenja dɛn we dɛn kɔl nyurotransmitta. Serotonin ɛn Norepinephrine na tu pan di men kemikal dɛn we de kɔntrol wi maynd, we min se wi kin fil gladi, kol at, ɛn gɛt trɛnk.
Pwɛl hat kin kam bikɔs dɛn kayn kemikal ya nɔr balans. Desipramine de wok bay we i de mek di sεrotonin εn norepinephrine na di bren go כp, we de εp fכ mek dεn wok bak. Dis mɛrɛsin de pan wan klas ɔf drɔgs we dɛn kɔl tricyclic antidepressants (TCA) .
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin
Bifo yu bigin fɔ tek Desipramine, i impɔtant fɔ gi yu dɔktɔ wan kɔmplit pikchɔ bɔt yu wɛlbɔdi kɔndishɔn. Dis mɛrɛsin nɔ kin gri wit sɔm mɛrɛsin dɛn. If yu gɛt ɛni wan pan dɛn tin ya, mek shɔ se yu tɛl yu dɔktɔ.
| Kɔndishɔn ɔ abit | Wetin mek yu nid fɔ tɛl di dɔktɔ? |
|---|---|
| If yu gɛt at sik ɔ yu bin dɔn gɛt at atak bifo | Dis mɛrɛsin kin afɛkt di at rit sɔmtɛm. |
| Tin dɛn we pɔsin kin tink bɔt fɔ kil insɛf, we i dɔn tray fɔ kil insɛf trade, ɔ we i dɔn gɛt famili istri we dɔn kil insɛf | Di mɛrɛsin wae de mɛk pɔrsin nɔr gɛt pwɛl hat sik, mɔr lɛk wae pɔrsin kin gɛt dis sik kin mek sɔm pipul dɛn de tink bɔt dɛn tin ya, so dɛn fɔ pe atɛnshɔn to am gud gud wan. |
| Ɔda maynd sik dɛm, lɛk bipolar disorder ɔr schizophrenia | Dis mɛrɛsin kin chenj ɔr mek dɛn sik dɛn de wɔs. |
| Liva sik | Na di liva de pul dis mɛrɛsin na di bɔdi. If di liva nɔ de wok fayn, di mɛrɛsin kin gɛda na di bɔdi. |
| Glaukoma kɔndishɔn we pɔsin kin gɛt | Dis mɛrɛsin kin mek di yay prɛshɔn go ɔp. |
| I nɔ izi fɔ pis, prɔblɛm wit prɔstat | Mɛrɛsin kin mek dis sik wɔs. |
| Epilepsy ɔr sik wae de mek pɔrsin fil bad (Seizures) . | Dis mɛrɛsin kin mek di risk fɔ mek pɔsin sik smɔl smɔl. |
| Wan prɔblɛm we pɔsin kin gɛt we i de drink | If yu miks rɔm ɛn dis mɛrɛsin, dat kin mek yu slip ɛn ɔda bad bad tin dɛn we kin apin to yu. |
| If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ | Yu fɔ tɔk to yu dɔktɔ if di mɛrɛsin kin afɛkt di pikin. |
| Alɛji to ɔda mɛrɛsin, it, ɛn day | Fɔ no if yu gɛt alɛji fɔ desipramine ɔ ɛni wan pan di tin dɛn we de insay am. |
Aw ɛksaktɔli a kin yuz dis mɛrɛsin?
I rili impɔtant fɔ tek di kɔrɛkt doz di rayt tɛm, jɔs lɛk aw di dɔktɔ tɛl yu.
- Swɛla dis pil wit wan glas wata.
- Gɛt di abit fɔ tek yu mɛrɛsin di sem tɛm ɛvride, lɛk aw yu dɔktɔ tɛl yu.
- Nɔ tek mɔ mɛrɛsin pas aw dɛn tɛl yu fɔ tek.
- Di tin we impɔtant pas ɔl na fɔ nɔ stɔp fɔ tek dis mɛrɛsin wantɛm wantɛm we yu nɔ gɛt yu dɔktɔ in advays. If yu du dat, yu kin gɛt sɔm sayn dɛn we yu kin gɛt fɔ lɛf fɔ drink rɔm lɛk fɔ gɛt diziz, nɔs, ɛn ed we de at. Ɔ yu sik kin wɔs. If yu stɔp, du am lɛk aw yu dɔktɔ tɛl yu, ɛn smɔl smɔl yu fɔ ridyus di doz.
Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?
If yu fɔgɛt fɔ tek wan doz, tek am jɔs lɛk aw yu mɛmba. Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks doz, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu dɔn sɛtul. Nɔ ɛva tek tu doz wan tɛm fɔ mek di doz we yu mis.
Wetin a go du if a tek bɔku mɛrɛsin?
If yu saspek se yu dɔn tek mɔ mɛrɛsin pas aw yu tink, nɔ tek am layt. Go na ɔspitul in Imejɛnsi Tritmɛnt Yunit (ETU) wantɛm wantɛm. Ɔ kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital .
Ɔda mɛrɛsin dɛm wae kin intarakt wit Desipramine
Desipramine kin intarakt wit bɔku ɔda mɛrɛsin dɛm, so i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛm wae yu de tek, lɛk di mɛrɛsin dɛm wae yu kin gi yu, di mɛrɛsin dɛm wae yu kin bay na kɔt, tradishɔnal mɛrɛsin dɛm, vaytamɛn dɛm, ɛn sɔpɔtmɛnt dɛm.
Dis dɔŋ ya na jɔs sɔm ɛgzampul dɛn.
- I rili denja fɔ tek Desipramine wit ɔda antidipreshan lɛk MAOI (e.g. Carbex, Marplan).
- Mεdisin dεm fכ mεntal sik lεk fεnotiazin (e.g. pεrfεnazin, klorpromazin).
- Sɔm mɛrɛsin fɔ at sik.
- Sɔm antibayɔtiks, lɛk Linezolid.
- I kin riak bak wit di tin dɛn we de insay sɔm mɛrɛsin dɛn we dɛn kin bay na kɔt fɔ kol, kɔf, ɛn alɛji.
So, aks yu dɔktɔ ɔltɛm bifo yu bigin fɔ tek ɛni nyu mɛrɛsin.
Tin dɛn we yu fɔ tek tɛm wit we yu de yuz di mɛrɛsin
- Yu fɔ no wetin yu de tink bɔt: Insay di fɔs wik dɛm wae yu bigin fɔ tek mɛrɛsin wae de mek yu nɔr fil bad, ɔr wae yu de chenj di doz, sɔm pipul dɛm kin tink bɔt fɔ kil dɛnsɛf, wɔri, nɔr kin rɛst, ɛn kin fil kwik kwik wan. If yu ɔ yu famili notis ɛni wan pan dɛn chenj ya, tɔk to yu dɔktɔ wantɛm wantɛm.Nɔ fred dis, bɔt i impɔtant fɔ no.
- Drɔw ɛn diziz: Dis mɛrɛsin kin mek yu fil fɔ slip ɛn diziz. So, nɔ drayv, wok na ayt, ɔ yuz mashin dɛn we nid fɔ de wach te yu no aw dis mɛrɛsin de afɛkt yu. Ɛspɛshali if yu na ol pɔsin, tinap stret we yu de grap we yu sidɔm ɔ we yu de grap na bed.
- Alkol: Nɔ drink rɔm ɔltogɛda we yu de tek desipramine. Rɔm kin rili mek di sayd ɛfɛkt dɛn we di drɔg gɛt, mɔ we pɔsin kin slip.
- Dray mɔt: Dis na kɔmɔn sayd ɛfɛkt. Yu kin ebul fɔ kɔntrol dis bay we yu de it gɔm we nɔ gɛt shuga, sok kandy we nɔ gɛt shuga, ɛn drink wata ɔl di de.
- Kɔnstipɛshɔn: Dis mɛrɛsin kin mek pɔsin gɛt kɔnstipɛshɔn. I impɔtant fɔ it mɔ it dɛn we gɛt fayv (frut, vɛjitebul) ɛn drink bɔku wata. If yu nɔ gɛt bɔdi fɔ pas 2-3 dez, tɛl yu dɔktɔ.
- San sɛnsitiviti: Yu skin kin fil mɔ to di san we yu de tek dis mɛrɛsin. So, yuz tin fɔ protɛkt yusɛf frɔm di san ɛn wɛr klos we de kɔba yu bɔdi we yu de go na do na di san.
Us sayd ɛfɛkt dɛn we a go gɛt?
Lɛk ɛni mɛrɛsin, Desipramine kin mek yu gɛt sayd ɛfɛkt, pan ɔl we nɔto ɔlman kin gɛt am. Di tebul we de dɔŋ ya ɛksplen dis klia wan.
| Sayd ɛfɛkt we pɔsin kin gɛt | Tɔk bɔt |
|---|---|
| Tin dɛn fɔ ripɔt to yu dɔktɔ wantɛm wantɛm | |
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip, tong, i nɔ izi fɔ blo. |
| Di chenj dɛn we de apin na di at rit | Fɔ fil lɛk se yu at de bit fast, at nɔ de bit ɔltɛm, yu de tɔn diziz, yu de fil pen na yu chɛst. |
| Sɛrotonin Sindrɔm we pɔsin kin gɛt | Nɔr de rɛst, yu mɔsul dɛn de stif ɔ yu de shek, yu de swet pasmak, yu gɛt ay fiva, yu de kɔnvuls, yu de vɔmit, yu gɛt dayarɛa. Dis na tin we rili denja. |
| Di bad bad tin dɛn we kin chenj di we aw pɔsin de fil | Fɔ tink bɔt fɔ kil yusɛf, fɔ wɔs pan pwɛl hat, fɔ fɛt. |
| Ɔda siriɔs sayn dɛn | Siz, ay pen wantɛm wantɛm, yu nɔ de si fayn, yu nɔ ebul fɔ pis. |
| If i kɔntinyu ɔ i de mɔna yu, tɛl yu dɔktɔ. | |
| Kɔmɔn sayd ɛfɛkt dɛn | Mɔt dray, slip, diziz, kɔnstipɛshɔn, nɔs, trem. |
| Ɔda | Chenj pan di we aw pɔsin want fɔ du mami ɛn dadi biznɛs ɔ di we aw i de wok. |
Mɛsej we dɛn kin kɛr go na os
- Desipramine na mɛrɛsin fɔ pwɛl hat. I kin tek sɔm wiks fɔ mek yu bɛnifit gud gud wan frɔm dis mɛrɛsin. So, peshɛnt ɛn tek di mɛrɛsin lɛk aw yu dɔktɔ tɛl yu.
- Nɔ stɔp fɔ tek di mɛrɛsin ɔ chenj di doz fɔ ɛni rizin if yu dɔktɔ nɔ advays yu.
- Tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek (inklud vaytamɛn ɛn tradishɔnal mɛrɛsin dɛn).
- Yu fɔ no mɔ bɔt aw yu de tink ɛn fil we yu fɔs bigin fɔ tek dis mɛrɛsin. If yu notis ɛni chenj we nɔ kɔmɔn, mɔ we yu de tink bɔt fɔ kil yusɛf, tɛl yu dɔktɔ wantɛm wantɛm.
- If yu tek bɔku mɛrɛsin, go na ɔspitul imejensi rum (ETU) wantɛm wantɛm ɔ kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta .
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Dɛn kin gi dɛn desipramine / Norpramin tablɛt fɔ us sik?
Dis na wan pan di ol ɛn pawaful (TCA - Tricyclic Antidepressant) saykayatrik drɔgs wae dɛn kin yuse fɔ trit siriɔs ‘Diprɛshɔn ɛn Wɔri’! Dis difrɛn smɔl frɔm ɔda TCA drɔgs (lɛk Amitriptyline). Wae di ɔda wan dɛm de mek di sikman slip/slip, dis pil de gi di sikman ‘Stimulating effect’ ɛn kip am aktif ɔl di de.
💬 Aw dis drɔg (Desipramine) de gi di pɔsin gladi ɛn ɛnaji di sem tɛm?
Pwɛl hat kin kam bikɔs di kεmεkal dεm we de mek yu gladi na di bren (Norepinephrine, Serotonin) de dכn. Wetin dis mεdisin bεsכl de du (pas fכ inkrεs di Serotonin) na fכ inkrεs di bren in kכnsantreshכn fכ wan kεmikכl we dεn kכl ‘Norepinephrine’ bay 100%, we de εliminet di bכdi εn gi di bren εnεji εn di ebul fכ fכs pan wan tin. Na dat mek dɔktɔ dɛn kin se dis to di wan dɛn we rili les ɛn we nɔ kin ebul fɔ grap na bed.
💬 Wetin na di men sayd effekt ɛn denja denja pas ɔl fɔ dis?
Bɔku denja dɛn de! (Anti-kolinεrjik ifekt dεm). Dis kin mek yu mɔt dray, i nɔ kin izi fɔ pis, ɛn yu kin gɛt diziz/layt ed we yu de kɔmɔt na bed. Di ɔda denja pas ɔl na dat i kin afɛkt di at bad bad wan! Risk de fɔ chenj di pɔsin in at ritm ɛn mek i gɛt wan sik we go kil am (Arrhythmia/Tachycardia).
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