Yu at nɔ de rit ɔltɛm? Mek wi lan bɔt Dofetilide!

Di dɔktɔ dɔn tɛl yu se prɔblɛm de wit yu at ritm, dat na di spid we yu at de bit? Yu go mɔs dɔn fil se yu de fred smɔl, nɔto so? Dofetilide na wan kayn mɛrɛsin we dɛn kin gi dɛn kayn tɛm ya. So, tide wi go tɔk bɔt dis mɛrɛsin we dɛn kɔl Dofetilide, lɛk se wi de tɛl wi padi.

Wetin na Dofetilide?

Fɔ tɔk am simpul wan, Dofetilide na mɛrɛsin we de mek pɔsin nɔ gɛt rit . Dis min se i de ɛp fɔ mek yu at ritm nɔmal. Bɔku tɛm i kin kam lɛk kapsul. Bɔku tɛm, dɛn kin tek am wan ɔ tu tɛm insay di de. Yu go dɔn si am ɔnda di brand nem Tikosyn®.

Bɔt wan tin de we wi fɔ mɛmba. Di doz fɔ dis mɛrɛsin, dat na di amount we dɛn gi yu fɔ drink, kin difrɛn frɔm wan pɔsin to ɔda pɔsin . If yu padi de tek dis mɛrɛsin, dɛn nɔ go gi yu di sem mɔni we dɛn gi am. Di dɔktɔ go asɛs yu kɔndishɔn ɛn gi yu di rayt doz (lɛk `125 mcg, 250 mcg` ɔ `500 mcg`). `(mcg)` tinap fɔ maykrogram.

Insay us kes dɛn dɛn kin yuz Dofetilide?

Dɛn kin yuse dis mɛrɛsin mɔ fɔ trit sɔm prɔblɛm dɛn we gɛt fɔ du wit at ritm ɛn fɔ mek dɛn nɔ kam bak.

Di prɔblɛm dɛn we kin mek pɔsin gɛt at ritm

• Atrial Fibrillation (Afib): Dis na we di כp chεmba dεm na yu at (dεn kin kכl am bak atria) de bit kwik kwik wan εn i nכ de bit, pas fכ bit di ritm. Tink bɔt am lɛk drɔm we dɛn se dɛn fɔ ple wan patikyula we, bɔt i de bit aut ɔf tiun ɛn kray. Dɛn kɔl dis ``Afib''.
• Atrial Flutter: Dis na ɔda abnɔmal at bit we de apin na di ɔpa chɛmba dɛm na di at. I sɔm kayn we fiba ``Afib``, bɔt sɔm smɔl difrɛns dɛn de.

Impɔtant: Insay dɛn tu tin ya, di at nɔ kin wok fayn, so dɛn nɔ kin pɔmp blɔd fayn fayn wan. Dis kin mek yu gɛt difrɛn prɔblɛm dɛn. So, dis mɛrɛsin de wok bay we i de kɔrɛkt da tin we nɔ de apin ɔltɛm ɛn mek di at wok fayn bak.

"Off-label" de yuz

Sɔntɛnde, dɔktɔ dɛn kin gi Dofetilide fɔ ɔda at prɔblɛm dɛn apat frɔm di we aw dɛn bin de yuz am fɔs. Dɛn kɔl dis "ɔf-lɛbul" yus. Dat min se, dɔktɔ dɛn no se di mɛrɛsin kin ɛp fɔ gɛt dɛn sik dɛn de, bɔt dɛn nɔ bin gri fɔ am fɔs fɔ dɛn sik dɛn de.

Ɔda kayn at ritm dizayd dɛm we fiba dis na:

• Ventricular Tachycardia: Insay dis, di lכw chεmba dεm na di at de bit kwik kwik wan.
• Supraventricular Tachycardias: Dis na bak we di at de bit kwik kwik wan we de apin na di כp chεmba dεm na di at. Ɔda kayn dɛn de apat frɔm `(Afib)` ɛn `(Atrial Flutter).`
• Wolff-Parkinson-White Syndrome: Dis na wan kכndyushכn we di at de bit fast bikoz fכ wan εkstra ilektrikal path na di at.

Aw fɔ stat Dofetilide?

Dis na spɛshal tin smɔl. We yu bigin fɔ tek Dofetilide, yu go gɛt fɔ de na ɔspitul fɔ lɛk tri to 4 dez . Dis kin tan lɛk se i strenj smɔl, nɔto so? Di rizin na bikɔs di dɔktɔ dɛn want fɔ wach aw di mɛrɛsin de afɛkt yu at ritm ɛn if yu gɛt ɛni nyu prɔblɛm. Dɛn go yuz dis tɛm bak fɔ fɛn di rayt doz fɔ yu. We yu de na ɔspitul, dɛn kin chenj di mɛrɛsin we dɛn de gi yu. Nɔ wɔri, dis na ɔl fɔ yu sef.

Aw fɔ tek Dofetilide na os?

Afta yu kam na os frɔm ɔspitul, di prɛskrishɔn lɛbl we dɛn gi yu go sho klia wan ɔmɔs fɔ tek ɛn ɔmɔs tɛm yu fɔ tek am insay di de.

I rili impɔtant fɔ mɛmba dɛn pɔynt dɛn ya:

• Tek di mɛrɛsin jɔs lɛk aw di dɔktɔ tɛl yu. Nɔ inkrisayz ɔ ridyus di doz.
• Tek di mɛrɛsin di sem tɛm ɛvride. If na mɔnin, tek am na mɔnin, if na nɛt, tek am na nɛt. Nɔ chenj di tɛm.
• Ivin if yu fil fayn, nɔ stɔp fɔ tek di mɛrɛsin. Kɔntinyu fɔ tek am as lɔng as yu dɔktɔ tɛl yu fɔ tek am.
• Yu kin tek dis mɛrɛsin wit it ɔ yu nɔ it am.
• Nɔ skip yu mɛrɛsin.
• Na di mɔni nɔmɔ we di dɔktɔ tɛl yu fɔ tek.

If yu gɛt ɛni kwɛstyɔn bɔt yu mɛrɛsin ɔ aw fɔ gɛt rifil, nɔ fred fɔ aks yu dɔktɔ ɔ fama. If sɔntin de we yu nɔ ɔndastand, aks dɛn fɔ ɛksplen am.

Wetin a fɔ tɛl mi dɔktɔ bifo a tek Dofetilide?

Bifo yu gi yu dis mɛrɛsin, i impɔtant fɔ tɛl yu dɔktɔ dɛn tin ya:

• Yu dɔn ɛva gɛt alɛji fɔ dofetilide? If na so, duya tɔk bɔt wetin apin.
• List ɔl di mɛrɛsin dɛn we yu de tek naw (prɛskrishɔn, ɔva-di-kɔnta (OTC), vaytamɛn, ɛn ɛbul sɔpɔtmɛnt). Nɔ bigin fɔ tek ɛni nyu mɛrɛsin ɔ sɔpɔtmɛnt if yu nɔ go to yu dɔktɔ fɔs.
• Tɛl wi if yu gɛt at sik, mɔ wan at sik we dɛn kɔl `Long QT Syndrome` , ɔ if yu gɛt kidni ɔ liva sik, ɔ if yu gɛt smɔl potashɔm ɔ magnɛsiɔm na yu blɔd.
• Mek shɔ se yu tɛl wi if yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ .

Us mɛrɛsin dɛn we yu nɔ fɔ tek wit Dofetilide?

If yu de tek dɛn mɛrɛsin ya, fɔ tek Dofetilide kin rili denja.So, if yu de yuz mɛrɛsin lɛk dis, yu fɔ rili tɛl yu dɔktɔ. Dɔn i nɔ go gi yu Dofetilide.

• Simɛtidin (fɔ ɛgzampul, Tagamet®) .
• Cisapride we dɛn kɔl Cisapride
• Dolutegravir (`Dɔlutegravir` - fɔ ɛgzampul, `Tivicay®`)
• Vɛrapamil (`Vɛrapamil` - fɔ ɛgzampul, `Calan®`)
• Ketokonazɔl we dɛn kɔl
• Itrakonazɔl (e.g. Sporanox®) .
• Trimɛtɔprim (`Trimɛtɔprim` - ɛgz. `Proloprim®`)
• Trimɛtɔprim wit sɔlfamɛtɔksazɔl (e.g., Bactrim®, Sɛptra®) .
• Haydroklorotiazayd (`Haydroklorotiazayd` - e.g. `Maykrozayd®`)
• Ziprasidone we gɛt di sik
• Trisayklik antidipreshan dɛm lɛk amitriptyline
• Prɔmɛtazin we dɛn kɔl Prɔmɛtazin
• Proklɔrpɛrazin (e.g., Kɔmprɔ®) .
• Kwinidin we dɛn kɔl
• Disopyramid (e.g., Nɔrpɛs®) .
• Sotalol (`Sotalol` - ɛgz., `Betapace®`) .

Ɔda mɛrɛsin dɛn we kin miks wit Dofetilide

Ɔda mɛrɛsin dɛn de we kin miks wit Dofetilide. Dis min se if yu tek dɛn mɛrɛsin ya togɛda, dɛn kin chenj aw Dofetilide de wok ɔ mek in sayd ɛfɛkt dɛn bɔku. So, if yu de tek ɛni wan pan di mɛrɛsin dɛn we de dɔŋ ya, tɔk to yu dɔktɔ bifo yu bigin fɔ tek Dofetilide.

• Amiodarone (`Amiodarone` - fɔ ɛgzampul, `Kɔdarɔn®`)
• Digoxin (`Digoxin` - fɔ ɛgzampul, `Lanoxin®`) .
• Metformin (`Mεtformin` - fכ egzampl `Glukofaj®`)
• Megestrol we dɛn kɔl Megestrol
• Diltiazem (fɔ ɛgzampul, Cardizem®) .
• Zafirlukast we de na di wɔl
• Kwinin we dɛn kɔl
• Flukonazɔl we dɛn kɔl
• Eritromaysin (`Eritromaysin` - fכ egzampl `PCE®`)
• Klaritromaysin we dɛn kɔl
• Fluoroquinolone antibayɔtiks lɛk Nɔflɔksasin ɛn Mɔksiflɔksasin
• SSRI dεm (Sεlektiv Sεrotonin Riuptek Inhibitor dεm) lεk Fluoxetine, Sertraline, Paroxetine (e.g. Paxil®) .
• Diuretics (mɛrɛsin we de pul wata na di bɔdi) lɛk Furosemide, Triamterene, ɛn Amiloride
• Protease inhibitors (mεdisin fכ sik dεm lεk HIV) lεk Indinavir

Jɔs fɔ no: Lɛk sɔm mɛrɛsin dɛn, if yu drink grep jus (frut we fiba grep) i kin mek di mɛrɛsin we dɛn kɔl dofetilide go ɔp na yu bɔdi. Dis kin mek pɔsin denja. So, aks yu dɔktɔ if i fayn fɔ drink grep jus we yu de tek dis mɛrɛsin.

Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?

If dis apin, tek di doz we yu mis as yu mɛmba . Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks doz we yu mɛmba, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu dɔn sɛtul. Nɔ ɛva tek dabl doz. If yu nɔ shɔ wetin fɔ du, tɔk to yu dɔktɔ ɔ fama.

Wetin na di bɛnifit dɛn we Dofetilide gɛt?

Dofetilide kin ɛp fɔ kɔntrol sɔm pan di at bit we nɔr de ɔltɛm na yu at, we kin mek yu layf izi smɔl. Bɔt, i impɔtant fɔ mɛmba se i nɔ de mɛn di sik ɔltogɛda.

Wetin na di sayd ɛfɛkt dɛm we Dofetilide gɛt?

Lɛk ɛni mɛrɛsin, Dofetilide kin mek sɔm sayd ɛfɛkt. Nɔto ɔlman kin gɛt dɛn, bɔt i fayn fɔ no bɔt dɛn.

Smɔl smɔl sayd ɛfɛkt dɛn we pɔsin kin gɛt:

• Chɛst de pen
• Ɛd we de at (ed we de at) .
• Diziz (vɛrtigo) .
• Nɔs (fɔ fil lɛk se yu de vɔmit) .
• Dayarɛa (bɛlɛ de at) .
• Bɛlɛ de pen

Sɔntin we wi fɔ rili tek tɛm wit:

Dɛn kin gi dofetilide fɔ kɔrɛkt di at bit we nɔ de bit ɔltɛm, bɔt risk de fɔ mek ɔda kayn at bit we nɔ de bit ɔltɛm wit dis mɛrɛsin. כl di at bit kwik kwik wan na di lכw chεmba dεm na di at (`ventricular tachycardia`) we dεn kכl ``Torsades de Pointes`` kin apin.

Dis na di men rizin we mek yu nid fɔ de na ɔspitul ɛn bigin fɔ tek mɛrɛsin! Di dɔktɔ dɛn want fɔ wach yu gud gud wan fɔ dis denja, abnɔmal at bit.

Aw kwik a go fil fayn afta a dɔn bigin fɔ tek di mɛrɛsin?

Dofetilide kin tek lɛk tu to tri awa so fɔ bigin wok. Bɔt ivin if yu fil fayn, nɔ stɔp fɔ tek di mɛrɛsin te yu dɔktɔ tɛl yu fɔ tek am. Kɔntinyu fɔ tek am.

Aw a go tek kia ɔf mi wɛlbɔdi we a de tek Dofetilide?

Sɔm tin dɛn de we yu fɔ du pan yu pat we yu de tek dis mɛrɛsin.

• Mek shɔ se yu go ɔl yu apɔntinmɛnt wit yu dɔktɔ, inklud di lab tɛst. Na da tɛm de yu kin si aw di mɛrɛsin de afɛkt yu.
• I go mɔs bi se yu go nid fɔ gɛt ilɛktrokardiogram (EKG) tɛst lɛk ɛvri siks mɔnt . Dis go chɛk di rit ɛn ritm we yu at de bit.
• Dɛn kin ɔda bak fɔ mek dɛn du blɔd tɛst fɔ si if dɛn nid fɔ chenj di mɛrɛsin we dɛn de tek.
• Ɔltɛm rid di infɔmeshɔn liflet we de kam wit yu mɛrɛsin, mɔ if ɛni chenj dɔn apin dis biɛn tɛm to yu mɛrɛsin ɔ yu wɛlbɔdi kɔndishɔn. Aks yu fama if yu gɛt ɛni kwɛstyɔn.

Mɔ tin dɛn we yu kin du:

• If yu de du ɛni ɔpreshɔn, dɛnt prosidur, ɔ imejensi tritmɛnt, tɛl di dɔktɔ ɔ dɛntist se yu de tek Dofetilide.
• Yu kin nid bak fɔ wɛr aydentifikeshɔn kad we de sho se yu de tek Dofetilide.
• Nɔ ɛva stɔp fɔ tek dis mɛrɛsin we yu nɔ aks yu dɔktɔ.
• Fɔ fala yu dɔktɔ in advays bɔt it ɛn drink, mɔ fɔ drink rɔm.
• Kip inof mɛrɛsin wit yu ɔltɛm. Bifo yu go vaykashun ɔ travul, chɛk fɔ si if yu mɛrɛsin de dɔn. If nɔto dat, yu nɔ go ebul fɔ fɛn am we ɛnitin apin.

Ustɛm yu fɔ go to dɔktɔ?

If yu gɛt ɛni wan pan dɛn sik ya, kɔl yu dɔktɔ wantɛm wantɛm ɔ go na imejensi rum:

• At bit fast ɔ i nɔ de bit ɔltɛm.
• Fɔ fil lɛk se yu at de bit fast, fil lɛk se yu at de bit.
• Chɛst de pen.
• Diziz ɔ fil lɛk se yu gɛt layt (`layt ed`).
• I nɔ kin izi fɔ yu fɔ blo.
• Sivɛri dayarɛa.
• Fɔ vɔmit wit we yu nɔ want fɔ it.
• Swet we nɔ kɔmɔn.
• Di tɔsti fɔ wata mɔ ɛn mɔ.
• Rash na di skin.

Ivin if sayd ɛfɛkt dɛn we nɔ kin rili siriɔs lɛk dɛn wan ya, tɔk to yu dɔktɔ if dɛn de mɔna yu:

• Ed de at.
• Nɔ ebul slip.
• Ɛni ɔda sayd ɛfɛkt we de mɔna yu.

Usay a kin bay Dofetilide?

Dofetilide nɔ de na ɔl di famasi dɛn. So, kɔl di famasi we de nia yu fɔ si if dɛn gɛt am. If yu gɛt prɔblɛm fɔ fɛn di mɛrɛsin, tɔk to yu dɔktɔ.

Aw fɔ kip Dofetilide?

• Stɔr Dofetilide insay kɔntena we dɛn lɔk tayt, na rum tɛmpracha, na dray ples .
• Nɔ put am usay di san de shayn dairekt ɔ na say we wam.
• Nɔ kip dis mɛrɛsin na say dɛn we gɛt bɔku wata, lɛk na di bafa. Mɔstɔ kin pwɛl di tin dɛn we di mɛrɛsin gɛt.
• Nɔto dis mɛrɛsin nɔmɔ nɔ fɔ kip, bɔt ɔl ɔda mɛrɛsin dɛn usay pikin dɛn nɔ go ebul fɔ rich.
• Nɔ ɛva sheb yu mɛrɛsin wit ɔda pɔsin.
• Nɔ ɛva yuz mɛrɛsin we dɔn pas. Sɔm mɛrɛsin paket dɛn gɛt wan de we dɛn rayt pan dɛn. Ɔ, if yu nɔ shɔ aw di mɛrɛsin ol, kɔl yu famasi ɛn aks.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

I kin rili mek yu at pwɛl fɔ no se yu gɛt prɔblɛm wit yu at ritm. Bɔt if yu dɔktɔ dɔn gi yu Dofetilide, i kin ɛp yu. Di tin we impɔtant pas ɔl na fɔ fala di dɔktɔ in instrɔkshɔn ɛn di instrɔkshɔn dɛn we de na di mɛrɛsin paket ɛksaktɔli. If yu gɛt ɛni ɔda kwɛstyɔn ɔ wɔri bɔt dis mɛrɛsin, nɔ shem fɔ aks yu dɔktɔ ɔ fama. Dɛn go ebul fɔ ɛp yu.

` Dofetilide, At palpiteshɔn, Aritmia, Atrial fibrilashɔn, Atrial fluta, Tikosyn, At sik