Yu dɔn ɛva wɔnda aw dɛn kin kɔntrol di shuga we de na wi blɔd? Wan spɛshal tin de we de ɛp wit dis we dɛn kɔl Glucagon. Lɛk smɔl hiro na wi bɔdi, Glucagon de mek wi blɔd shuga lɛvɛl nɔ go tu smɔl. Tide, wi go tɔk bɔt dis Glucagon ditayli ɛn rili simpul.
Wetin na Glucagon?
Fɔ tɔk am simpul wan, glukagon na wan ɔmon we wi bɔdi kin mek . yu no, na di alfa sεl dεm na wi pankrias de mek am. We wi blɔd glukɔs lɛvɛl go dɔŋ, we wi nɔ de it fɔ lɔng tɛm (we wi de fast fɔ lɔng tɛm), we wi de du ɛksɛsayz tranga wan, ɔ we wi it it we gɛt bɔku prɔtin, dis glukagon de kɔmɔt.
Tink bɔt am, glukɔs na di men kayn shuga we de na wi blɔd. Wi kin gɛt dis glukɔs frɔm di kabɔhaydrɛt dɛn we de insay di tin dɛn we wi de it ɛn drink. Dis shuga na in de gi ɛnaji to wi bɔdi in ɔgan dɛm, mɔsul dɛm, ɛn nervɔs sistɛm. I tan lɛk petrol fɔ motoka. So, wi bɔdi kin kip dis blɔd shuga lɛvɛl na di rayt lɛvɛl insay wan we we rili kɔmpleks. Ilɛksɛf dis tu bɔrku ɔr tu smɔl, difrɛn sik ɛn diskɔmfɔt kin kam.
Glucagon injɛkshɔn ɛn nos sprɛy
apat frכm di glukagon we de na di nכmal, sεntetik glukagon dεm de bak. Dɛn kin gi dɛn tin ya as injɛkshɔn ɔ as dray nos sprɛy. Yu go dɔn si se dɛn kin yuz dis pan imejensi, mɔ fɔ pipul dɛn we gɛt Tayp 1 dayabitis , we dɛn blɔd shuga kin go dɔŋ tumɔs wantɛm wantɛm (haypoglycemia). di glukagon we dεn gi dis tεm de rilis di glukכs we dεn stכr na wi liva εn i de mek wi bכdi shuga lεvεl go כp kwik kwik wan. I tan lɛk se yu de gi wi smɔl ‘boost’.
Wetin glukagon de du to wi bɔdi?
If yu pankrias de wok fayn, yu bɔdi go tek tɛm kɔntrol di glukɔs we de na yu blɔd. Dis kin apin mɔ bay tu ɔmon dɛn we dɛn kɔl glukagɔn ɛn insulin . Fɔ ɛgzampul, we di shuga na yu blɔd go dɔŋ tumɔs (haypoglycemia), yu pankrias de pul mɔ glukagon. Dis glukagon de ɛp fɔ mek yu blɔd shuga go ɔp difrɛn we dɛn:
- fכs, glukagon de go na wi liva εn i de kכnvכlt di glukכs we dεn stכr de – we wi kכl glycogen – to sכmtin we wi kin yuz. Dɔn di liva kin pul am insay di blɔd.
- Sɛkɔn, glukagon kin stɔp di liva fɔ tek ɛn kip glukɔs, ɛn lɛf mɔ glukɔs na di blɔd.
- Tɔd, amino asid dɛnGlucagon de ɛp bak fɔ mek di bɔdi mek glukɔs frɔm ɔda tin dɛn.
Mɛmba se i tan lɛk sisaw. We di blɔd shuga go dɔŋ, glukagon de wok, ɛn we di blɔd shuga go ɔp, insulin de wok!
Us sik dɛn kin gɛt fɔ du wit prɔblɛm wit di glukagon wok?
Naw lɛ wi si us prɔblɛm dɛn kin apin if glukagon nɔ wok fayn.
If yu gɛt dayabitis, yu bɔdi nɔ go ebul fɔ pul inof glukagon we yu blɔd shuga nɔ bɔku. Dis kin mek yu gɛt smɔl shuga na yu blɔd bɔku tɛm, ɔ ivin yu blɔd shuga smɔl . Dis risk kin bɔku mɔ if yu tek mɛrɛsin dɛn we de mek yu blɔd shuga go dɔŋ lɛk insulin ɔ sulfonylureas.
Na sɔm pipul dɛm wae gɛt tayp 2 dayabitis, di glukagon lɛvɛl kin pas di nɔmal, we yu kɔmpia am wit di blɔd shuga lɛvɛl. Dis na wan rizin bak we mek di shuga na di blɔd kin bɔku.
I nɔ kin izi fɔ mek prɔblɛm wit glukagon prodakshɔn apin we yu nɔ gɛt dayabitis, bɔt sɔm tin dɛn de we i kin apin:
- Pankrias: If yu gɛt dayabitis bikɔs ɔf pankrias ɛn tek insulin fɔ am, yu kin gɛt glukagon dɛfisiɛns bak. Dis kin mek di risk fɔ lɛ di blɔd shuga nɔ bɔku.
- Glucagonoma: Dis na wan tumbu we nɔ kin bɔku na di pankrias. I de rilis tumɔs glukagon. Dis kin mek yu gɛt sɔm sayn dɛm lɛk ay blɔd shuga, skin rɔsh, ɛn we yu de lɔs yu wet.
- Multiple Endocrine Neoplasia (MEN): Dis na bak wan jεnεtik kכndyushכn we rili rεs. insay dis, di tכmכro dεm de divεlכp na mכr dan wan gland na yu εndokrin sistεm. Dis inklud di pankrias.
- Di sayd ɛfɛkt dɛm we dɛn kin pul pan di pankrias: If fɔ sɔm rizin dɛn pul pat ɔ ɔl yu pankrias, di sɛl dɛm we de mek glukagon ɛn insulin kin lɔs.
Wetin na di sayn dɛm fɔ prɔblɛm wae gɛt fɔ du wit glukagon?
As wi bin dɔn tɔk, if di glukagon lɛvɛl nɔ de wok fayn, dat kin mek di blɔd shuga nɔ bɔku (haypoglycemia) ɔ di blɔd shuga go ɔp (hyperglycemia). Lɛ wi tek wan luk pan wetin na dɛn sayn dɛn de.
Di sayn dɛn we de sho se yu blɔd shuga nɔ bɔku (Hypoglycemia) .
Imajin se yu padi, Nilanthi, de tek mɛrɛsin fɔ dayabitis. Wan de, wantɛm wantɛm i bigin fɔ shek, swet, ɛn fil lɛk se in ed de tɔn. I tan lɛk bak se i de slɔp in wɔd dɛn we i de tɔk. If dɛn sik ya apin, i kin min se in blɔd shuga rili smɔl.
Di kɔmɔn sayn dɛm na:
- I de shek shek, i de shek shek
- Swet ɛn fil kol
- Diziz, fil lɛk yu ed layt
- Di at we de blo
- Angri
- I nɔ izi fɔ kɔnsɛntret, kɔnfyushɔn
Impɔtant: If yu gɛt dɛn sik ya, i rili impɔtant fɔ it sɔntin we gɛt shuga, it ɔ drink we gɛt bɔku kabɔhaydrɛt kwik kwik wan . Dis go ɛp yu blɔd shuga fɔ kam bak to nɔmal. If yu kin gɛt dɛn sik ya ɔltɛm, yu fɔ rili go to yu dɔktɔ.
Di sayn dɛn we de sho se yu gɛt bɔku blɔd shuga (Hyperglycemia) .
Bɔku tɛm, di ay blɔd shuga (haypa glycemia) kin bi bikɔs yu nɔ gɛt insulin, nɔto prɔblɛm wit glukagon nɔmɔ. Bɔt di prɔblɛm dɛn we kin apin to di glukagon we nɔ kin apin so ɔltɛm kin mek bak di blɔd shuga bɔku. Di fɔs sayn dɛn na:
- Fɔ tɔsti ɔltɛm ɛn/ɔ angri
- Di vishɔn we nɔ klia
- Fɔ pis bɔku tɛm ( fɔ pis bɔku tɛm) .
- Ed de at
If yu gɛt dɛn sik ya, i rili impɔtant fɔ go to dɔktɔ.
Us tɛst dɛn kin du fɔ chɛk di glukagon lɛvɛl?
If yu gɛt sɔm sayn dɛn, yu dɔktɔ kin tɛl yu fɔ du blɔd tɛst fɔ no if yu gɛt glukagon. Insay dis tɛst, dɔktɔ ɔ nɔs kin yuz nidul fɔ tek blɔd sɛmpul frɔm yu vein. Dɔn dɛn kin sɛn am na wan lɛb fɔ mek dɛn tɛst am.
Wetin na di nɔmal glukagon lɛvɛl?
nכmal wan, di כmכnt fכ glukagon we wi fכ gεt na wi bכdi de bitwin 50 εn 100 pikogram pan wan mililita (pg/mL) . Pikogram na wan trilyɔn pat pan wan gram! Na rili smɔl mɔni, nɔto so?
Bɔt mɛmba se dɛn nɔmal valyu ya kin difrɛn smɔl frɔm wan lab to ɔda lab. Dɛn kin difrɛn bak dipen pan aw lɔng yu dɔn de fast ɛn aw yu blɔd shuga bin de di tɛm we dɛn de du di tɛst. So, ɔltɛm kɔmpia yu rizɔlt wit di valyu dɛn we de na yu blɔd tɛst ripɔt . If yu gɛt ɛni kwɛstyɔn, tɔk to yu dɔktɔ.
Ustɛm a fɔ go to dɔktɔ bɔt mi glukagon lɛvɛl?
If yu gɛt dayabitis ɛn yu de gɛt bɔku tɛm we yu blɔd shuga nɔ bɔku ɔ yu gɛt bɔku, i impɔtant fɔ go to dɔktɔ. Dɛn nɔ kin mɛzhɔ di glukagon lɛvɛl pan pipul dɛn we gɛt dayabitis. Bɔt yu kin nid fɔ chenj di we aw yu de du tin wit dayabitis fɔ mek dɛn nɔ gɛt dɛn kayn sik ya.
Pan ɔl we ɔda prɔblɛm dɛn we gɛt fɔ du wit glukagon nɔ kin bɔku, if yu gɛt sɔm sayn dɛn, i impɔtant fɔ fɛn di kɔz. So, mek shɔ se yu go to yu dɔktɔ.
Wetin na di difrɛns bitwin Glucagon ɛn Glycogen?
Yu tink se dɛn tu pipul ya nɔto di sem? Glycogen na wan kayn glukɔs (shuga) we dɛn kin kip na di liva.wi bכdi de kip glycogen mεntal wan na di liva εn mכsul dεm.
Glucagon na כmon we de gi signal fכ di liva fכ kכnvכlt glycogen bak to glukose. Dɔn da glukɔs de go insay di blɔd ɛn wi bɔdi kin yuz am as ɛnaji.
Wetin kin apin to glukagon we yu de fast?
We wi de fast, glukagon rili impɔtant fɔ mek wi blɔd shuga nɔ go dɔŋ tumɔs. Dis na bikɔs wi bɔdi nɔ de gɛt glukɔs frɔm it da tɛm de.
we wi fast fכ lכng tεm, glukagon de mek di bכdi mek glukכs frכm tin dεm we nכ de fכ kכbכhaydret – lεk lipid dεm, amino asid dεm, εn protin dεm. dis prכsεs dεn kכl am gluconeogenesis .
Fɔ dɔn, a fɔ se... (Tek-Home Message)
So, yu go ɔndastand se glukagon na wan rili impɔtant ɔmon we de ɛp fɔ kip wi blɔd shuga lɛvɛl wɛl ‘biɛn di tin dɛn we de apin’. I nɔr kin izi fɔ mek yu gɛt dayabitis ɔr prɔblɛm wae gɛt fɔ du wit glukagon.
Bɔt if yu de gɛt sayn dɛn ɔltɛm we de sho se yu blɔd shuga nɔ bɔku ɔ yu blɔd shuga, duya go to yu dɔktɔ. Dɔn dɛn kin fɛn di kɔz ɛn gi yu di tritmɛnt we yu nid. Fɔ kia fɔ yu wɛlbɔdi na di tin we impɔtant pas ɔl.
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Glucagon na mεdisin we de lכs bכdi shuga lεk Insulin?
Nɔ! dis na כmon na di bכdi we de wok lεk di ‘ivil bכda/opכsite sayd' fכ insulin. Insulin de fos di bɔdi in shuga lɛvɛl fɔ go dɔŋ. bכt ‘glucagon’, we di bכdi in shuga lεvεl dכn dכn denja lכw (Hypoglycemia), de כda di shuga we dεn stכr na di liva (Glycogen) fכ go insay di bכdi wantεm wantεm εn ‘rεs di shuga lεvεl bak to nכmal’.
💬 Wetin mek dis Glucagon ɔmon de na di famasi as imejensi tritmɛnt?
If pɔsin we gɛt dayabitis tek tumɔs mɛrɛsin ɔ insulin ɛn i ‘lɔ blɔd shuga/wantɛm wantɛm i kam na kɔma ɛn i nɔ no natin’ (Hypoglycemia), i nɔ kin ebul fɔ it shuga da tɛm de (i kin stɔp). Na da tɛm de nɔmɔ, if dɛn injɛkt ‘Glucagon Pen’ (we na imejensi injɛkshɔn) insay in pant ɔ in shɔl, di blɔd shuga na di bɔdi kin go ɔp insay sɔm minit ɛn di pɔsin we sik kin gɛt kɔnshɛns bak.
💬 I izi fo injekt dis glukagon injekshon na os?
Yɛs! Dis na jɔs lɛk di EpiPen fɔ alɛji, ɛn i kam insay wan imejensi kit we di famili mɛmba dɛn kin injɛkt izi wan na os. (Na sɔm kɔntri dɛn, i kin de bak as nos sprɛy/Baqsimi.) If pɔsin de na os we de tek insulin fɔ dayabitis, i rili impɔtant fɔ kip dis glukagon injɛkshɔn na frij ɔ kɔba fɔ mek yu nɔ day wantɛm wantɛm.
` glukagon, blɔd shuga, haypoglycemia, haypa glycemia, dayabitis, pankrias, ɔmon
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