Yu dɔn ɛva yɛri bɔt HTLV-1 (Human T-lymphotropic Virus type-1)? Lɛ wi tɔk bɔt am!

Yu go mɔs dɔn yɛri bɔt vayrɔs lɛk `HIV`. Bɔt yu nɔ go dɔn yɛri bɔku bɔt di vayrɔs `HTLV-1`. Dis na wan kayn vayrɔs bak we kin go insay wi bɔdi in sɛl dɛn ɛn mek wi gɛt sik. Bɔt nɔr wɔri, fɔ bɔrku pipul dis nɔr go bi big prɔblɛm. Bɔt i fayn fɔ no, nɔto so? So lɛ wi si wetin na `HTLV-1`, aw i de divɛlɔp, ɛn wetin dɛn kin du bɔt am.

Wetin na `HTLV-1`? Lɛ wi ɔndastand am simpul wan!

`HTLV-1` tinap fɔ `Human T-lymphotropic Virus tayp-1` . dis de pan wan grup fכ vayrus dεm we dεn kכl `Retrovirus`. Yu mɛmba se wi bin tɔk bɔt `HIV` (HIV) vayrɔs we na `Retrovirus`? wan pan di spεshal tin dεm fכ dεn `Retrovirus` ya na we dεn de enta wi sεl dεm, dεn jεnεtik infכmeshכn, dat na dεn `jεnεtik mεtirial`, de insay di `DNA` (DNA) fכ wi sεl dεm. Imajin am lɛk se wan vayrɔs dɔn go insay kɔmpyuta.

di `HIV` vayrus εn di `HTLV-1` vayrus tu de atak di `T sεl dεm` na wi imyun sistεm. Bɔt di we aw dɛn de wok rili difrɛn. `HIV` de pwεl di `T sεl dεm` εn i de wik di imyun sistεm. bכt `HTLV-1` nכ de pwεl dεn kayn `T sεl dεm` ya. Infakt, bɔrku pipul dɛm wae gɛt `HTLV-1` nɔr de sho ɛni simptom. Dɛn de liv jɔs lɛk pipul dɛn we gɛt wɛlbɔdi.

Bɔt, na smɔl pan di pipul dɛn we gɛt di sik kin gɛt tu sik bɔku ia afta dat, sɔntɛm 30 to 60 ia afta dat. Wan na wan kayn blɔd kansa we dɛn kɔl Adult T-cell Leukemia/Lymphoma (ATL ɔ ATLL). di כda wan na wan sik we de na di nεv sεstem we dεn kכl HTLV-1- asosiet Myelopathy/Tropical Spastic Paraparesis (HAM/TSP).

Ɔda kayn `HTLV` de?

Yes, difrεn kayn `HTLV` vayrus dεm de we de infεkt mכtalman. fכ egzampl, `HTLV-1`, `HTLV-2`, `HTLV-3` εn `HTLV-4` de. Ɔl dɛn tin ya kin mek pɔsin gɛt di sik fɔ ɔl in layf. כltu, te naw, na `HTLV-1` nכmכ de mek spεshal sik dεm.

Aw kɔmɔn dis `HTLV-1`? Yu tink se i de na Sri Lanka?

Di `HTLV` vayrɔs de na bɔku say dɛm na di wɔl. di masta sabi pipul dεm se bitwin 5 εn 20 milyan pipul dεm na di wכl gεt di sik wit `HTLV-1`. Bɔt di infɛkshɔn rit kin difrɛn bad bad wan bitwin kɔntri ɛn rijyɔn.

Fɔ ɛgzampul, na Nɔt Amɛrika, nɔto 1% pan di pipul dɛn gɛt am. Bɔt na sɔm pat dɛn na Jepan, Afrika, Sawt Amɛrika, Ɔstrelia, Iran, ɛn sɔm pat dɛn na di Karibian, dɛn kin ripɔt se pas wan pat pan tri pipul dɛn gɛt dis sik. I at fɔ fɛn klia data bɔt di tin we de apin na Sri Lanka, bɔt i impɔtant fɔ no bɔt dɛn kayn vayrɔs ya.

Wetin na di sayn dɛm fɔ dis? Yu tink se i kin apin to ɔlman?

As wi bin dɔn tɔk bifo tɛm, .Bɔrku pipul dɛm wae gɛt HTLV-1 nɔr de sho ɛni sayn. Dɛn nɔ ivin no se dɛn gɛt di vayrɔs. Di simptom dεm de sho כnli ia afta di infεkshכn, we di kכndyushכn dεm we wi bin dכn tכk bכt, lεk ATL כ HAM/TSP, de divεlכp.

Di simptom dɛm fɔ `ATL` (Adult T-cell Leukemia/Lymphoma) kin inklud:

• Fɔ fil taya ɔltɛm (`Fatigue`) .
• Skin rash, kɔndishɔn dɛn we tan lɛk ɛkzema
• di limf no dεm we swεla – lεk na di nεk, di armpit dεm, εn di groin
• Banbɛlɛ
• Memori lɔs, kɔnfyushɔn
• Bɔn pen

di simptom dεm fכ `HAM/TSP` (HTLV-1-asכsiet mayopati/tropik spastik paraparesis) kin inklud:

• Wik ɔ stif we de go ɔp smɔl smɔl na wan ɔ ɔl tu di leg dɛn
• Bak pen
• Urinary incontinence
• di limb dεm we de sכmtεm sכmtεm, tingling sensation (Peripheral neuropathy) .

Us ɔda sik dɛn kin kam wit `HTLV-1`?

Na lɛk wan pan ɛvri 20 pipul dɛm (lɛk 5%) we gɛt di HTLV-1 vayrɔs kin gɛt kɔndishɔn we dɛn kɔl ATL (kansa) ɔ HAM/TSP (nyurolɔjik sik).

• `ATL` na wan kayn kansa we de divεlכp na di bכdi . i gεt sεvεra sכbtayp dεm bak (lεk `acute`, `lymphoma`, `smoldering`, `krכnik`). Di tritmɛnt ɛn prɔgnosis fɔ ɛni kayn kin difrɛn smɔl.
• `HAM/TSP` na sik we de afɛkt di nervɔs sistɛm. I gɛt sɔm tin dɛn we fiba di sik we dɛn kɔl `Multiple Sclerosis` (`MS`). I kin mek di mɔsul dɛn wik ɛn gɛt prɔblɛm wit di nervɔs sistɛm we de go bifo.

Apat frɔm dɛn tu men sik ya, sɔm pipul dɛn we de stɔdi bɔt dis dɔn kam fɔ no se HTLV-1 kin mek sɔm sik dɛn bak we kin mek pɔsin gɛt inflammatory ɛn autoimmune diseases . Bɔt di rayt rilayshɔn bitwin dɛn stil nɔ klia. Sɔm pan dɛn sik ya na:

• Dɛmatitis we dɛn kɔl Dɛmatitis
• Atraytis we pɔsin kin gɛt
• Inflameshɔn na di insay pat dɛn na di yay (`Uveitis`) .
• Di sik we dɛn kɔl Sjögren in sindrom

Aw sik dɛn we gɛt fɔ du wit HTLV-1 kin kam? Wetin mek nɔto ɔlman kin gɛt dɛn?

we di `HTLV-1` vayrus go insay wi bכdi, i de go stret to di `CD4` sεl dεm (dεn kכl dεm bak `helper T-cells`) insay wi imyun sistεm. dis `CD4` sεl dεm lεk wi bכdi in polis כfisa dεm, na wan kayn sεl we de εp fכ protεkt wi frכm sik.

naw, rεtrovayrus dεm lεk HTLV-1 de kכri dεn jεnεtik infכmeshכn insay wan mכlikul we dεn kכl RNA. We dɛn go insay wi sɛl dɛn, di vayrɔs kin tek sɛns fɔ chenj in RNA to sɔntin we fiba di DNA we gɛt wi sɛl dɛn infɔmeshɔn. Dɔn, di pat pan di DNA (we dɛn kɔl provayrɔs) we i dɔn mek kin put insɛf insay wi sɛl dɛn DNA. In ɔda wɔd dɛn, di vayrɔs kin put wan pat pan insɛf insay di softwe we de kɔntrol wi sɛl dɛn.

naw wi sεl dεm, we de tink se di pat pan di vayrus in `DNA` na pat pan dεn sεf, de bigin fכ mek mכr kכpi fכ di vayrus. dis nyu kכpi dεm fכ di `HTLV` vayrus de go εn infεkt bכku mכr `CD4` sεl dεm. Pan ɔl we di vayrɔs kin skata na di bɔdi dis kayn we, i nɔ kin gɛt ɛni sayn.

כltu, insay sכm pipul dεm, afta plεnti ia, dis infεkshכn de mek dεn bכdi de prodyuz tu mכch `T sεl dεm`. Na da tɛm de wan kɔndishɔn we dɛn kɔl `ATL` lukimiya kin apin. כda kes dεm, dis vayrus kin infεkt di nεv sεstem εn mek wan kכndyushכn we dεn kכl `HAM/TSP`. Dɛn stil de du risach bɔt wetin mek dis kin apin to sɔm pipul dɛn nɔmɔ.

Aw dis `HTLV-1` vayrɔs kin kɔmɔt frɔm wan pɔsin to ɔda pɔsin?

difrεn men we dεm de we di `HTLV-1` vayrus kin transmit. I rili impɔtant fɔ no bɔt dɛn tin ya:

• Tru mami ɛn dadi biznɛs: mami ɛn dadi biznɛs wit yu vagina, anal ɔ ɔral we nɔ gɛt protɛkshɔn.
• Frɔm mama to pikin tru di pikin we i de gi in bɛlɛ: We mama we gɛt di sik de gi in pikin in bɛlɛ.
• Bay we yu de sheb nidul: Ɛspɛshali pan pipul dɛn we de injekt drɔgs.
• Rarely: Na tru fɔ transfyuz blɔd ɔ transplant ɔgan transplant. Bɔt na bɔku kɔntri dɛn, naw dɛn kin chɛk fɔ no if pɔsin gɛt di vayrɔs fɔ gi blɔd ɛn ɔgan dɛn, so i nɔ kin izi fɔ mek i pas am tru dɛn we ya.

Udat de pan ay risk fɔ gɛt `HTLV-1`?

Bɔku tin dɛn de we kin mek di risk fɔ gɛt HTLV-1 infɛkshɔn bɔku:

• Injekt drɔgs we yu nɔ gɛt prɛskrishɔn.
• Fɔ bɔn ɔ liv na eria usay di `HTLV` vayrɔs bɔku.

Sɔm eria dɛn we gɛt bɔku HTLV-1 infɛkshɔn na:

• Sawt Wɛst pat na Jepan
• Afrika kɔntri dɛn we de na di sawt pat na di Sahara Dɛzat (`Sab-Saharan Afrika`)
• Sɔm pat dɛn na Sawt Amɛrika
• Di Ayland dɛn na di Karibian
• Nɔtan Iran
• Sɛntral Ɔstrelia

Impɔtant: Ivin insay di sem kɔntri, di nɔmba fɔ di sik nɔ kin di sem na ɔl di eria dɛn. Sɔm smɔl smɔl say dɛn kin gɛt bɔku bɔku infɛkshɔn, ivin if di ɔl rit nɔ bɔku.

Wetin na di prɔblɛm dɛn we kin apin we pɔsin gɛt HTLV-1?

di `HTLV-1` vayrus nכmכ nכ de wik di imyun sistεm. כltu, if `ATL` (kansa) כ `HAM/TSP` (nyurolכjik sik) de divεlכp, di imyun sistεm kin wik.Dis kin mek yu gɛt opportunistic infection wae nɔr kin de pan pipul dɛm wae gɛt wɛl bɔdi. Sɔm pan dɛn sik ya kin mek pɔsin in layf de pan denja.

Aw yu kin no kɔrɛkt wan if yu gɛt `HTLV-1` infɛkshɔn?

Dɔktɔ dɛn kin no if pɔsin gɛt HTLV-1 bay we dɛn de du blɔd tɛst. dis tεst de luk fכ antibodi dεm (antibodi dεm) we dεn dכn prodyuz na di bכdi agens di HTLV vayrus, כ fכ di prεsεns fכ di vayrus in jεnεtik mεtirial (RNA).

Bɔt dis nɔto tɛst we ɔlman kin du ɔltɛm. Dɔktɔ kin rifer yu fɔ dis tɛst pan dɛn kayn tin ya:

• If yu gɛt mɛdikal kɔndishɔn (e.g., simptom dɛm fɔ ATL ɔ HAM/TSP) we yu tink se kin gɛt fɔ du wit HTLV-1 infɛkshɔn.
• If yu de na eria usay HTLV infɛkshɔn kin bɔku ɛn yu de plan fɔ gi pikin in bɛlɛ.
• If yu de op fɔ bi pɔsin we de gi blɔd ɔ pɔsin we de gi ɔgan (dis naw na tɛst we dɛn fɔ du na bɔku say dɛn).

Tritmɛnt de fɔ `HTLV-1`? Yu tink se dɛn kin mɛn am?

Fɔ tɔk tru, no mɛrɛsin nɔ de yet fɔ di `HTLV-1` vayrɔs. Dat min se dɛn nɔ go ebul fɔ pul di vayrɔs kɔmɔt na di bɔdi kpatakpata. כltu, tritmεnt dεm de fכ di sik dεm `ATL` εn `HAM/TSP` we `HTLV-1` de kכz.

Dɛn kin yuz dɛn tin ya as tritmɛnt fɔ `ATL` (kansa):

• Di mɛrɛsin dɛn we dɛn kin yuz fɔ ɔda kayn limfoma, fɔ ɛgzampul, kemotɛrapi .
• Antivayrɔs mɛrɛsin dɛn, lɛk zidovudine (Retrovir®) ɛn intafɛron alfa. Bɔt nɔto ɔl kayn ATL kin ansa dɛn antivayrɔs mɛrɛsin ya.
• Stem sɛl we dɛn kin transplant . Dis nɔ pɔsibul fɔ ɔlman we gɛt ATL. Bɔt if i wok fayn, i kin mek pɔsin liv lɔng pasmak.

Fɔ pipul dɛm wae gɛt `HAM/TSP` (nyurolɔjik sik), dɛn kin yuse dɛn tritmɛnt ya fɔ kɔntrol di sik dɛm ɛn gi dɛn rilif:

• `Intɛrfɛrɔn alfa`.
• Ridyus inflameshn wit `Kɔtikosterɔyd`.
• Intɛrfɛrɔn beta. Dis kin ɛp fɔ ridyus di inflamɛns ɛn mek di nerv dɛn nɔ pwɛl.
• Ridyus di mɔsul spastisiti ɛn stiffness wit Baclofen (Lioresal ®) ɔ tizanidine.
• Oxybutynin fɔ mek yu nɔ ebul fɔ urinary.

Wetin kin apin if a gɛt `HTLV-1`? A fɔ wɔri?

Dis na di tin we impɔtant pas ɔl. Nɔto ɔlman we gɛt di HTLV-1 vayrɔs go gɛt ɛni wan pan di ATL ɔ HAM/TSP. Infakt, bɔku pan di wan dɛn we gɛt di sik kin liv nɔmal layf ɛn nɔ gɛt dɛn siriɔs sik ya.

Bɔt if yu gɛt dɛn kayn tin ya, di we aw yu go si tin go dipen pan di kayn we aw yu gɛt. Pipul wae gɛt di kayn ATL wae de smok ɔr kin gɛt bɛtɛ tin fɔ du pas di wan dɛm wae gɛt ɔda kayn ATL. Pan ɔl we HAM/TSP kin wɔs as tɛm de go, yu kin liv fɔ bɔku bɔku ia afta dɛn dɔn no se yu gɛt di sik.

Aw a go protɛkt misɛf frɔm dis `HTLV-1` vayrɔs? Ɛni we dɛn de fɔ mek i nɔ apin?

Yes, tin de we wi kin du fɔ mek di `HTLV-1` vayrɔs nɔ go skata.

• We yu tɛst di blɔd ɛn ɔgan dɛn we dɛn dɔn gi fɔ HTLV-1, dat kin ɛp fɔ mek di vayrɔs nɔ skata.
• Yu kin du dɛn tin ya fɔ ridyus yu yon risk:
• Nɔ injekt drɔgs we yu nɔ gɛt prɛskrishɔn.
• Nɔ yuz di sem injɛkshɔn nidul dɛn bak ɔ sheb dɛn wit ɔda pipul dɛn.
• Nɔ du mami ɛn dadi biznɛs we yu nɔ gɛt protɛkshɔn. Yuz latex kɔndɔm ɔltɛm we yu de du ɛni kayn mami ɛn dadi biznɛs (vagina, anal, ɔ ɔral).
• If dɛn dɔn tɛst yu se yu gɛt HTLV-1, nɔ gi pikin bɔbi ɛn gi blɔd. If yu gɛt HTLV-1 ɛn yu want fɔ gi pikin in bɛlɛ, go to dɔktɔ we gɛt ɛkspiriɛns pan HTLV-1. If yu ɛksprɛs di mama in milk ɛn friz am, dɔn yu thaw am, dat kin mek yu nɔ gɛt di vayrɔs to yu pikin, bɔt i impɔtant fɔ go to dɔktɔ bifo yu du dat.

Wetin `HTLV` pɔsitiv min?

Fɔ bi `HTLV` pɔsitiv min se yu gɛt `HTLV-1` ɔ ɔda kayn `HTLV` na yu bɔdi. I nɔ min se yu go rili divɛlɔp `ATL` ɔ `HAM/TSP`. If yu gɛt `HTLV-1` pɔsitiv, tin dɛn de we yu kin tek fɔ mek yu nɔ go prɛd di vayrɔs to ɔda pipul dɛn (lɛk fɔ nɔ gi pikin bɔbi, fɔ avɔyd fɔ du mami ɛn dadi biznɛs we nɔ gɛt protɛkshɔn).

Aw dis `HTLV` denja?

Di `HTLV` vayrɔs, we dɛn tek am in wan, i nɔ kin denja ɛn i nɔ kin mek pɔsin gɛt di sik. Bɔt i impɔtant fɔ no bɔt am, bikɔs sɔntɛnde `HTLV-1` kin mek yu gɛt kansa, nyurolɔjik sik, ɔ inflammatory kɔndishɔn.

Ustɛm a fɔ go to dɔktɔ?

If yu gɛt kwɛstyɔn bɔt fɔ gɛt tɛst fɔ HTLV-1, ɔ if yu gɛt HTLV-1 ɛn yu want fɔ no wetin yu fɔ tek tɛm wit, mek shɔ se yu tɔk to dɔktɔ. I impɔtant mɔ fɔ no bɔt dis if yu de na say usay HTLV-1 bɔku.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

Okay, so wi don tok plenti abaut `HTLV-1,' no bi so? Mɛmba se pan ɔl we dis na vayrɔs we de ɔlsay na di wɔl, i nɔ kin bɔku na bɔku say dɛn. Na smɔl pan di wan dɛn we gɛt di sik kin gɛt siriɔs sik.

Di tin we impɔtant pas ɔl na, nɔ wɔri fɔ tɛst pɔsitiv fɔ HTLV-1.Bɔrku pipul kin liv wɛl bɔdi layf wae nɔr gɛt ɛni sayn. Bɔt fɔ no bɔt dis vayrɔs, aw i de skata, ɛn aw fɔ avɔyd am, dat kin ɛp fɔ protɛkt yusɛf ɛn di wan dɛn we de arawnd yu.

If yu gɛt ɛni ɔda kwɛstyɔn bɔt dis, nɔ shek fɔ aks yu famili dɔktɔ ɔ dɔktɔ we no bɔt dis. Stay wit wɛlbɔdi!

` HTLV-1, Rεtrovayrus, ATL, HAM/TSP, Kansa, Nyurolכjik sik, Vayral infεkshכn