Yu gɛt Tayp 2 Dayabitis? Yu dɔktɔ go dɔn gi yu wan pil we dɛn kɔl Jardiance. Yu kin want fɔ no mɔ bɔt dis mɛrɛsin. Us kayn mɛrɛsin na am, wetin kin apin to yu bɔdi, ɛn us tin dɛn fɔ tek tɛm wit. So tide, lɛ wi tɔk smɔl bɔt Jardiance, aw i de wok, di bɛnifit dɛn we i gɛt, ɛn wetin yu fɔ no bɔt.
Wetin na Jardiance? Aw i de wok na di bɔdi?
Jardiance na mɛrɛsin wae dɛn kin yuse fɔ trit big pipul ɛn pikin dɛm wae gɛt tayp 2 dayabitis. I de wok bay we i de kɔntrol di shuga we de na di blɔd. I kin ɛp bak fɔ ridyus di risk fɔ gɛt at atak ɛn strok pan big pipul dɛn we gɛt dayabitis. Bɔt dɛn nɔ gri fɔ mek dɛn gɛt tayp 1 dayabitis. Sɔmtɛm dɛn kin yuse am bak pan pipul dɛm wae nɔr gɛt shuga bɔt wae gɛt at pwɛl ɔr kidni sik.
Okay, naw mek wi si aw dis de wok. Fɔ tɔk am simpul wan, wetin wi kidni dɛn kin du na fɔ filta di shuga (glukɔs) we de na di blɔd ɛn tek am bak insay di bɔdi. Dɛn nɔ de mek i kɔmɔt na di urine.
wan spεshal protin de we de εp di kidni dεm fכ dis wok we dεn kכl SGLT2 (Sodium-glucose cotransporter-2) .
di Jardiance pil de blok di akshכn fכ di SGLT2 protin fכ sכm tεm. dis de mek di ekstra shuga we di bכdi nכ kin ebul fכ tek bak fכ pas tru di urine. Dis kin mek di shuga we de na di blɔd go dɔŋ. Dis prɔses kin ɛp yu bak fɔ lɛf fɔ it sɔm wet ɛn kɔntrol yu blɔd prɛshɔn .
Aw mak dɛn dɔn pruv di bɛnifit dɛn we dis mɛrɛsin de gi?
Dɛn dɔn du bɔku big klinik stɔdi fɔ no aw Jardiance sef ɛn ifektiv. Dɛn stɔdi ya bin men wan luk aw di drɔg bin wok fɔ ridyus HbA1c (wan tɛst we de sho di avɛrej blɔd shuga lɛvɛl fɔ di pas 3 mɔnt).
Di stɔdi dɛn bin gɛt big pipul dɛn we gɛt tayp 2 dayabitis, pikin dɛn we ol 10-17 ia, pipul dɛn we gɛt sik na dɛn kidni, ɛn pipul dɛn we gɛt at sik. Dɛn bin kɔmpia di ifɛkt dɛn we di drɔg gɛt bak wit ɔda dayabitis mɛrɛsin dɛn (e.g., insulin, mɛtfɔmin, glimepiride).
Okay, naw lɛ wi si wetin di rizɔlt fɔ dɛn stɔdi ya dɔn fɛn. Mɛmba se dɛn tin ya na avrej tin dɛn we kin apin. Yu rizulyt kin difrɛn difrɛn wan bay yu bɔdi.
| Rizult fɔ big pipul dɛn (Adult wit Tayp 2 Dayabitis) | ||
|---|---|---|
| Di doz fɔ di mɛrɛsin | Di blɔd shuga we yu de fast we yu de fast (mg/dL) de go dɔŋ . | HbA1c we dɔn go dɔŋ |
| Jardiance 10 mg (we nɔ gɛt ɔda mɛrɛsin) . | Bay lɛk 19 mg/dL | Bay lɛk 0.7% . |
| Jardiance 25 mg (we nɔ gɛt ɔda mɛrɛsin) . | Bay lɛk 25 mg/dL | Bay lɛk 0.8% . |
| Jardiance (wit ɔda mɛrɛsin dɛn) . | bay bכt 10 - 22 mg/dL | Bitwin 0.2% - 2.1% . |
| Di tin dɛn we kin apin to big pipul dɛn we gɛt at sik | |
|---|---|
| Tritmɛnt | Pasɛnt pan di wan dɛn we kin day bikɔs ɔf at atak, strok, ɔ sik dɛn we de mek dɛn at ɛn blɔd |
| Jardiance 10 mg ɔ 25 mg | 10.5% na di . |
| Plɛsɛbo we dɛn kɔl | 12.1% na di . |
Rizult fɔ pikin ɛn kidni pasɛnt dɛn
Dɛn dɔn sho se jardiance kin ridyus di HbA1c lɛvɛl ɛn di fast blɔd shuga lɛvɛl na pikin dɛn we ol 10-17 ia. I dɔn ɛp bak fɔ ridyus di HbA1c lɛvɛl pan big pipul dɛn we gɛt dayabitis ɛn kidni sik.
Ɔda mɛrɛsin dɛn kin miks wit Jardiance?
Yɛs, i rili impɔtant fɔ tek kia ɔf dis.
- Lɔw blɔd shuga: If yu tek ɔda mɛrɛsin fɔ dayabitis, mɔ insulin ɔ sulfonylureas (lɛk glimepiride), yu kin gɛt lɔw blɔd shuga (hypoglycemia) we yu bigin Jardiance. So, yu dɔktɔ kin ridyus di doz fɔ yu ɔda mɛrɛsin dɛn.
- Dehydration: If yu de tek diuretics, if yu tek am wit Jardiance, i kin mek yu gɛt dehydration. So, i impɔtant fɔ drink bɔku wata.
- Lithium: If yu de tek lithium fɔ wan mental kɔndishɔn, in ifɛkt kin chenj we yu bigin Jardiance. Tɔk to yu dɔktɔ bɔt dis ɛn du blɔd tɛst if nid de.
Aw fɔ avɔyd di bad bad tin dɛn we kin apin to pɔsin?
Dis pat rili impɔtant. Pan ɔl we Jardiance na mɛrɛsin we rili yusful, sɔm siriɔs sayd ɛfɛkt dɛn de we wi fɔ no bɔt.
1. Dayabitik Kεtoasidכsis (DKA): .
- Dis na tin we de mek pɔsin denja smɔl. We di bɔdi nɔ ebul fɔ yuz shuga, i kin yuz ɔda we fɔ gɛt ɛnaji. Dis kin mek kemikal dɛn we dɛn kɔl ketɔn . We dɛn tin ya gɛda na di blɔd, dɛn kin rili denja.
- Di sayn dɛm: nɔs, vɔmit, bɛlɛ kramp, taya pasmak, i nɔ kin izi fɔ blo.
- > If yu gɛt dɛn sik ya, stɔp fɔ tek Jardiance wantɛm wantɛm ɛn go to dɔktɔ ɔ go na ɔspitul imejensi rum (ETU). Dis na imejensi.
2. Infɛkshɔn dɛn:
- Dis mɛrɛsin de mek di shuga we de na di urine bɔku, we de mek di risk fɔ gɛt baktri ɛn yist infɛkshɔn go ɔp. Infεkshכn kin apin na di urinary tract, blad, εn jεnital εria.
- Fournier’s Gangrene: Na wan sik we nɔ kin apin so ɔltɛm, bɔt we kin rili denja we kin apin rawnd di say we di uman in bɛlɛ de. Go to dɔktɔ kwik kwik wan if yu gɛt pen, rɛd, ɔ swel na di say wit fiva ɛn wik.
3. Prɔblɛm dɛn we gɛt fɔ du wit di leg ɛn fut:
- Sɔm stɔdi dɔn sho se di wan dɛn we dɛn kin kɔt dɛn an kin bɔku smɔl, mɔ pan pipul dɛn we gɛt di sik we dɛn kɔl peripheral artery disease.
- So tek tɛm chɛk yu fut ɛvride.If yu gɛt ɛni wund, ɔlsa, krak krak, ɔ sayn fɔ se yu gɛt di sik, tɛl yu dɔktɔ wantɛm wantɛm.
4. Di tin dɛn we kin apin to di kidni dɛn:
- If yu nɔ gɛt wata na yu bɔdi, dat kin afɛkt di we aw yu kidni de wok. So, i impɔtant fɔ drink bɔku wata. Yu dɔktɔ kin tɛl yu fɔ du blɔd tɛst fɔ chɛk aw yu kidni de wok.
5. Alɛji Riakshɔn:
- If yu gɛt siriɔs alɛji lɛk fɔ swel na yu lip, yu fes, ɔ yu tɔng, yu nɔ kin ebul fɔ blo, ɔ yu gɛt rɔsh na yu skin, stɔp fɔ tek di mɛrɛsin wantɛm wantɛm ɛn go to dɔktɔ.
Aw fɔ yuz di mɛrɛsin kɔrɛkt wan?
Jardiance na pill we yu kin tek wan tɛm insay di de. Tek di doz (10mg ɔ 25mg) we yu dɔktɔ gi yu.
- I bɛtɛ fɔ tek am na mɔnin: Bɔku dɔktɔ dɛn kin se yu fɔ tek am na mɔnin. Di rizin na dat i de mek di pikin de pis bɔku bɔku wan, so dat i kin apin na di de we i nɔ go ambɔg di slip na nɛt.
- Aw yu go no if di mɛrɛsin de wok?: Yu kin no bay we yu blɔd shuga lɛvɛl ɛn HbA1c dɔn go dɔŋ. Bɔt i kin tek lɛk 3 mɔnt fɔ mek yu HbA1c chenj. If yu du urine test we yu de tek Jardiance, i go sho se shuga de na yu urine. Dis na nɔmal tin, nɔ wɔri bɔt am. I min se di mɛrɛsin de wok.
Mɛsej we dɛn kin kɛr go na os
- Jardiance na mɛrɛsin fɔ tayp 2 dayabitis we de mek di blɔd shuga go dɔŋ bay we i de pul di shuga na di urine.
- Ɔltɛm tek di doz nɔmɔ we yu dɔktɔ tɛl yu fɔ tek, di tɛm we yu tɛl yu (i bɛtɛ fɔ tek am na mɔnin).
- Drink bɔku wata ɔl di de fɔ mek yu nɔ gɛt wata na yu bɔdi.
- Yu fɔ no di sayn dɛm we de sho se yu blɔd shuga nɔ bɔku (haypoglycemia) ɛn di denja simptom dɛm fɔ dayabitik ketoacidosis (DKA) (vomit, bɛlɛ pen, at fɔ blo). Go to dɔktɔ wantɛm wantɛm if yu gɛt sayn dɛn fɔ DKA.
- Chek yu fut ɛvride fɔ wund, sos, ɔ sayn dɛn fɔ infekshɔn.
- Tɔk to yu dɔktɔ bɔt ɛni sayd ɛfɛkt ɔ prɔblɛm we yu gɛt. Nɔ ɛva stɔp fɔ tek yu mɛrɛsin ɔ chenj di doz if yu nɔ gɛt dɔktɔ advays.
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