Yu gɛt Tayp 2 Dayabitis? Ɔ na at ɔ blɔd vesel kɔndishɔn? If na so, yu dɔktɔ go dɔn gi yu wan mɛrɛsin we dɛn kɔl Empagliflozin, we dɛn kin kɔl bak Jardiance. Dɛn kin gi dis mɛrɛsin bak to pipul dɛm wae nɔr gɛt shuga bɔt gɛt sɔm kayn at pwɛl hat sik. So, bikɔs dis na mɛrɛsin we dɛn de gi bɔku pipul dɛn naw, lɛ wi tɔk bɔt am smɔl mɔ tide, lɛk se wi de tɔk to wi padi.
Aw dis drɔg Empagliflozin (Jardiance) de wok?
Dis kin tan lɛk sayɛns smɔl, bɔt i rili simpul. Dis mεdikeshכn de pan wan klas כf drog dεm we dεn kכl SGLT2 inhibito dεm. di ful nem na Sכdiכm-glukoz kכ-transpכta 2 inhibito.
Okay, naw in simpul wɔd, dis na wetin kin apin:
wi kidni dεm gεt wan protin we dεn kכl SGLT2. I wok na fɔ tek bak di shuga (glukɔs) frɔm di blɔd bak insay di bɔdi. empagliflozin de blok dis protin we dεn kכl SGLT2. Dɔn , di kidni dɛn nɔ kin tek di shuga we pasmak na di blɔd bak insay di bɔdi, bɔt bifo dat, dɛn kin pas am na di urine. I tan lɛk se filta de pul tin dɛn we dɛn nɔ want. dis we ya, dεn kin kכntro di εksyכs shuga lεvεl na di bכdi.
dis mεdisin de ridyus bak di riabsכpshכn fכ sכdiכm (sכlt) frכm di kidni dεm insay di bכdi. Dis kin mek di wok we de na di at nɔ bɔku. Na dat mek dis mɛrɛsin kin fayn bak fɔ pipul dɛn we gɛt at sik.
Wetin yu fɔ ɛkspɛkt we yu de yuz dis mɛrɛsin?
Empagliflozin na wan pil we yu kin tek wan tɛm insay di de. I bɛtɛ fɔ mek yu stik to di sem tɛm ɛvride. Bɔku tɛm, dɔktɔ dɛn kin tɛl yu fɔ tek am na mɔnin. Yu kin tek am wit it ɔ yu nɔ it am.
Dis mεdikeshכn de insay tu trεnk: 10 miligram (10 mg) εn 25 miligram (25 mg). Yu dɔktɔ kin stat yu wit smɔl doz ɛn afta dat i kin inkrisayz di doz if nid de.
Wetin fɔ du if yu fɔgɛt? If yu fɔgɛt fɔ tek wan pil, tek am jɔs afta yu mɛmba. Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks pil, nɔ tek di pil we yu mis ɛn di nɛks wan di sem tɛm. Skip di pil we yu mis ɛn tek di nɛks pil di tɛm we yu dɔn sɛtul.
Sɔntɛnde yu dɔktɔ go gi yu dis mɛrɛsin wit ɔda mɛrɛsin fɔ dayabitis. Fɔ ɛgzampul, yu kin gɛt am wit mɛtfɔmin (we dɛn kɔl Synjardy) ɔ wit linagliptin (we dɛn kɔl Glyxambi) as wan pil.
Fɔ mek yu gɛt di bɛst pan dis mɛrɛsin, i impɔtant fɔ it fayn it ɛn ɛksesaiz ɔltɛm , lɛk aw yu dɔktɔ tɛl yu fɔ du. Ɛn nɔ fɔgɛt fɔ drink bɔku wata ɔl di de.
We yu de tek dis mɛrɛsin, wan wan tɛm yu dɔktɔ go du blɔd tɛst fɔ chɛk aw yu kidni dɛn de wok fayn. I go tɛl yu bak fɔ chɛk yu blɔd shuga ɔltɛm. I kin tek 6 mɔnt fɔ mek dɛn fil di ful ɛfɛkt fɔ dis mɛrɛsin.
Wetin na di sayd ɛfɛkt dɛm we dis kin gɛt?
Lɛk ɛni mɛrɛsin, dis wan kin gɛt smɔl smɔl sayd ɛfɛkt dɛn. Bɔt nɔ wɔri, bɔku pan dɛn nɔ siriɔs. Lɛ wi tek wan luk pan wetin na dɛn sayd ɛfɛkt ya.
| Sayd ɛfɛkt we pɔsin kin gɛt | Diskripshɔn ɛn wetin fɔ du |
|---|---|
| Di Kɔmɔn Sayd Ɛfɛkt dɛn | |
| Yist Infεkshכn dεm na di Jεnital εria | I kin apin mɔ pan uman dɛn, bɔt i kin apin to man dɛn bak. Di sayn dɛm na fɔ it, pen, swel, rɛd, ɛn wata we de kɔmɔt na di wata. Tritmɛnt de fɔ dɛn tin ya, so go to dɔktɔ if yu gɛt dɛn sik ya. |
| Infεkshכn dεm na di urinary tract (UTI) . | Sɔm sayn dɛm lɛk fɔ bɔn, pen, fɔ pis ɔltɛm, fɔ pis wit klawd, ɔ fɔ gɛt blɔd. Bɛlɛ pen kin apin bak. Tɛl yu dɔktɔ bɔt dɛn tin ya bikɔs dɛnsɛf nid tritmɛnt. |
| Ɔda smɔl smɔl sayd ɛfɛkt dɛn | Yu kin gɛt tin dɛn lɛk we yu de tɔsti mɔ ɛn mɔ, yu kin pis ɔltɛm, yu kin gɛt nɔys, yu jɔyn dɛn kin pen, ɛn yu kin gɛt infekshɔn na yu trot. Dɛn tin ya kin go as tɛm de go as yu bɔdi de ajɔst to di mɛrɛsin. If dɛn kɔntinyu fɔ du dat, tɛl yu dɔktɔ. |
| Siriɔs Sayd Ɛfɛkt dɛn we nid fɔ pe atɛnshɔn to kwik kwik wan | |
| Siriɔs infɛkshɔn dɛn na di urinary tract | Fiva, kol, bad bad pen na di lכw bכdi כ bak. Dis kin bi sayn dɛm fɔ se infɛkshɔn de afɛkt di kidni dɛm. Go to dɔktɔ wantɛm wantɛm. |
| Lɔw Blɔd Prɛshɔn | Diziz, layt ed, mɔ we yu tinap. |
| Di blɔd shuga we nɔ bɔku | Sɔm kayn sik lɛk fɔ swet, fɔ shek shek, at rit we de go ɔp, angri, ɛn kɔnfyushɔn kin apin, mɔ we yu tek am wit ɔda mɛrɛsin fɔ dayabitis. |
| Fournier in wan sik we dɛn kɔl gangrene | Dis na wan rili rare, siriɔs infekshɔn na di say we di uman in bɔdi de. Di sayn dɛm na di say we yu de fil bad bad wan, yu kin swel, yu kin gɛt fiva, ɛn yu kin taya pasmak. Dis na imejensi, go na di ɔspitul in Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm. |
| Dayabitik ketoacidosis we pɔsin kin gɛt | Wan rili siriɔs kɔndishɔn we kin kam bikɔs ɔf di blɔd shuga we bɔku. Di sayn dɛm na fɔ tɔsti pasmak, fɔ pis bɔku tɛm, fɔ gɛt bɛlɛ pen, fɔ nɔs, fɔ fil wik, ɛn fɔ gɛt frut smel na yu briz. Dis na imejensi bak, go na ETU wantɛm wantɛm. |
| Alɛji Riakshɔn dɛn | Skin rash, swel na yu fes, lip, ɔ trot, i nɔ izi fɔ swɛla ɔ blo. Dis na imejensi bak, go to dɔktɔ wantɛm wantɛm. |
Wonin ɛn sef we yu fɔ no bifo yu yuz am
Bifo yu bigin dis mɛrɛsin, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud di mɛrɛsin fɔ ɔda sik dɛn, vaytamɛn, sɔpɔtmɛnt, ɛn tradishɔnal mɛrɛsin). Empagliflozin kin intarakt wit dɛn mɛrɛsin ya mɔ:
- Ɔda mɛrɛsin dɛn fɔ gɛt dayabitis
- Blɔd prɛshɔn mɛrɛsin dɛn lɛk ACE inhibitor ɛn Angiotensin riseptɔ blɔk (ARB) .
- Diuretik ɔ "wata pils".
- Di mɛrɛsin dɛn we de mek pɔsin fil pen lɛk aspirin, ibuprofen, ɛn naproxen
Yu dɔktɔ kin nid fɔ chenj di doz fɔ ɔda mɛrɛsin dɛn we yu de tek ɔ tek tɛm mɔ bɔt di sayd ɛfɛkt dɛn.
If yu gɛt sayn dɛm fɔ ketoacidosis, yu dɔktɔ kin aks yu bak fɔ chɛk yu blɔd fɔ keto. Spɛshal divays ɔ urine tɛst strip dɛn de fɔ dis.
Nɔ fɔgɛt fɔ drink bɔku wata , bikɔs dis mɛrɛsin kin mek yu nɔ gɛt wata na yu bɔdi.
Tɛl yu dɔktɔ if yu de drink rɔm, ɛn if yu gɛt yist infɛkshɔn ɔ yurinary tract infɛkshɔn ɔltɛm.
Udat nɔ fɔ tek dis mɛrɛsin?
Empagliflozin nɔ fayn fɔ ɔlman. Sɔm tin dɛn de we yu nɔ fɔ tek dis mɛrɛsin:
- If yu de du kidni dayalaysis.
- If yu na mama we de gi pikin in mama in bɛlɛ (di mɛrɛsin kin pas to di pikin tru in mama in milk).
- If yu gɛt bɛlɛ ɔ yu de plan fɔ gɛt bɛlɛ (as i kin ambɔg di pikin, tɔk to yu dɔktɔ bɔt dis).
- If yu gɛt alɛji fɔ empagliflozin ɔ ɛni wan pan di tin dɛn we de insay am.
Dɔn bak, dɛn nɔ gri fɔ tek dis mɛrɛsin fɔ pipul dɛn we gɛt Tayp 1 Dayabitis, bikɔs i kin mek dɛn gɛt Ketoacidosis mɔ ɛn mɔ.
Aw Ɛmpagliflozin (Jardiance) kin wok fayn?
Dɛn dɔn rayt bɔt aw dis mɛrɛsin de wok fayn fayn wan insay klinik trial dɛn. Insay wan stɔdi we dɛn du fɔ 6 mɔnt pan big pipul dɛn we gɛt tayp 2 dayabitis, Empagliflozin:
- di blכd shuga lεvεl dεm we yu de fast dεn jεnarali dכn dכn bay lεk 19-25.
- di A1c valyu, we de sho se di avrej bכdi shuga lεvεl dεm ova di pas 2-3 mכnt, dεn dכn dכn bay 0.7% - 0.8%.
Apat frɔm dat, sɔm pipul dɛn bak dɔn lɔs dɛn wet . di wan dεm we tek di 10mg doz fכ wan de lכs lεk 2.5% pan dεn bכdi wet (fכ egzampl, bכt 2.25 kg fכ 90 kg pכsin). di wan dεm we tek di 25mg dכz lכs 2.8% pan dεn bכdi wet (fכ egzampl, bכt 2.5 kg fכ 90 kg pכsin).
Dɛn dɔn si bak se di sistolik blɔd prɛshɔn dɔn go dɔŋ smɔl pan di wan dɛn we bin tek dis mɛrɛsin.
Mɛsej we dɛn kin kɛr go na os
- Empagliflozin (Jardiance) na wan mɛrɛsin wae dɛn kin yuse fɔ trit shuga ɛn sɔm kayn hat sik. I de wok bay we i de ɛp di kidni dɛn fɔ pul di shuga we pasmak na di bɔdi tru di urine.
- Tek dis mɛrɛsin jɔs lɛk aw yu dɔktɔ dɔn tɛl yu, di sem tɛm ɛvride. If yu mis wan doz, nɔ tek tu doz di sem tɛm di nɛks tɛm.
- Infεkshכn na di urinary tract εn jεnital yist infεkshכn na kכmכn wit dis mεdikal. Tɛl yu dɔktɔ if yu gɛt ɛni wan pan dɛn sik ya.
- Drink bɔku wata ɔl di de bikɔs dis mɛrɛsin kin mek yu nɔ gɛt wata na yu bɔdi.
- I impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek.
- If yu gɛt siriɔs sik dɛn lɛk we yu gɛt siriɔs alɛji, i nɔ izi fɔ blo, Fournier’s gangrene, ɔ ketoacidosis , go na ɔspitul in imejensi dipatmɛnt (ETU) wantɛm wantɛm.
- Nɔ ɛva stɔp fɔ tek dis mɛrɛsin if yu nɔ gɛt dɔktɔ advays.
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