Yu de mek tumɔs blɔd sɛl dɛn na yu bɔdi? Lɛ wi lan bɔt dɛn Myeloproliferative Neoplasms (MPN) ya!

Yu dɔn ɛva tink bɔt wetin go apin if yu bon mɛro mek bɔku blɔd sɛl dɛn insay yu bɔdi? Na so di myeloproliferative neoplasm, ɔ MPN fɔ shɔt, tan lɛk. Dis na blɔd kansa we nɔ kin apin so ɔltɛm, bɔt we kin mek pɔsin in layf de pan denja ɛn we kin kil pɔsin if dɛn nɔ mɛn am fayn. Lɛ wi tɔk bɔt am simpul wan we yu go ɔndastand.

Wetin na dis mayloproliferativ niɔplasm (MPN)?

Fɔ tɔk am simpul wan, myeloproliferative neoplasms (MPN) na tin dɛn we yu bon mɛro (wan sɔft tisu we de insay yu bon dɛn) de mek mɔ rɛd blɔd sɛl, wayt blɔd sɛl, ɔ pletlɛt (sɛl dɛn we de ɛp yu blɔd fɔ klɔt). Tink bɔt am lɛk faktri we de mek bɔku tin dɛn. Dis kin apin we sɔntin nɔ apin we dɛn de mek blɔd sɛl.

Bɔku tɛm dɛn MPN kɔndishɔn ya kin divɛlɔp rili sloslo . So sɔm pipul dɛn nɔ kin gɛt ɛni sayn fɔ lɔng tɛm. na dat mek dεn kin kכl dεm bak "krכnik" כ lכng tεm mayloproliferativ niכplasm. Bɔt, insay rare kes dɛm, dɛn MPN kɔndishɔn ya kin divɛlɔp to sɔntin we siriɔs pasmak.

Bɔt nɔr wɔri, gud tritmɛnt de fɔ kɔntrol de sayn dɛm fɔ dis sik ɛn fɔ mek i nɔr siriɔs.

Us kayn MPN dɛn de?

Bɔku kayn MPN dɛn de. Ɛni wan pan dɛn kin afɛkt di kayn blɔd sɛl dɛn we yu bon mɛro kin mek pasmak. Sɔntɛnde, na rɛd blɔd sɛl nɔmɔ dɛn kin mek, ɛn ɔda tɛm dɛn na wayt blɔd sɛl ɔ pletlɛt nɔmɔ dɛn kin mek. insay sכm tכp dεm fכ MPN, wan kכmbaynshכn fכ dεn kayn sεl dεm ya kin prodyuz pasmak. Wan ɔda rizin na bikɔs dɛn sɛl dɛn ya we pasmak kin biev difrɛn frɔm di blɔd sɛl dɛn we gɛt wɛlbɔdi.

Udat dɛn dis kayn tin kin afɛkt mɔ?

Tu pan di men tin dɛm we de afɛkt di we aw MPN de apin na yu ej ɛn yu man ɔ uman .

• Ej: Pan ɔl we MPN kin apin to pipul dɛn we gɛt ɔl kayn ej, dɛn kin si am mɔ pan pipul dɛn we ol 50, 60, ɔ pas dat .
• Jɛnda: Fɔ ɛgzampul, polycythemia vera, we na wan kayn MPN, kin bɔku pan man dɛn. Essential thrombocythemia de mכr kכmכn pan uman dεm. Ɔda kayn MPN kin afɛkt ɔl tu di man ɛn uman ikwal.

Aw MPN de afɛkt yu bɔdi?

Dɛn sik ya we gɛt fɔ du wit blɔd kin apin we yu bon mɛrɔ de mek bɔku pan wan patikyula kayn blɔd sɛl pas aw yu bɔdi nid. So, di ifɛkt we dis gɛt pan yu bɔdi dipen pan us kayn blɔd sɛl dɛn de mek pasmak . Fɔ ɛgzampul, wan kayn MPN kin mek yu gɛt at atak ɔ strok. Wan ɔda kayn we kin mek pɔsin nɔ gɛt bɛtɛ blɔd.

Fɔ ɔndastand dɛn kayn tin ya we nɔ kin apin so ɔltɛm, i go fayn fɔ mek yu ɔndastand smɔl bɔt aw dɛn mek yu bon mɛro ɛn blɔd sɛl dɛn. Ɔl wi blɔd sɛl dɛn kin bigin as stem sɛl dɛn na yu bon mɛro. dis bon mכro na di sכft, spכnj tisu we de insay yu bon dεm. di stεm sεl dεm we de divεlכp frכm am kin bi mayloid stεm sεl dεm כ limfoyd stεm sεl dεm.

• Limfoyd stεm sεl dεm na di kayn wayt bכdi sεl dεm we de fכt infεkshכn.
• di mayloid stεm sεl dεm kin gi rεd bכdi sεl dεm (we de kכri כksijεn כlsay na di bכdi), כda kayn wayt blכd sεl dεm, εn pletlεt dεm (we de εp fכ stכp blכd we i apin).

Lɛk ɔl ɔda sɛl dɛn, dɛn stem sɛl dɛn ya de wok akɔdin to di instrɔkshɔn dɛn we di jin dɛn gi dɛn. nכmal wan, dεn stεm sεl dεm ya de sheb εn bכku as nid de insay yu bon mכro fכ mek nyu sεl dεm. Bɔt if chenj de na dɛn jin ya, dat min se if di jin dɛn chenj, dɛn jin dɛn de kin sɛn di rɔng instrɔkshɔn to di stem sɛl dɛn fɔ kɔntinyu fɔ sheb ɛn bɔku. Afta sɔm tɛm, dɛn blɔd sɛl dɛn ya we pasmak kin gɛda na di bon mɛro ɔ na di blɔd vesel dɛn, ɛn dis kin mek di blɔd nɔ ebul fɔ flɔ. We dis blɔd nɔ de flɔ, siriɔs wɛlbɔdi prɔblɛm kin apin.

Wetin na di kayn MPN we dɛn kin gɛt mɔ?

tri kayn MPN dεm de we kכmכn pas כl: polycythemia vera, εsεnsial trombocythemia, εn praymar myelofibrosis.

Polisaytemia Vɛra

Dis na di kayn MPN we kɔmɔn pas ɔl . I kin apin we yu bon mɛro mek tumɔs rɛd blɔd sɛl dɛn . Dis kin mek yu blɔd tik ɛn slo. Pipul wae gɛt polycythemia vera kin gɛt bɔrku risk fɔ gɛt blɔd klɔt. Dɛn klɔt ya kin mek pɔsin gɛt at atak ɛn strok. Na smɔl tɛm nɔmɔ dis sik kin tɔn to siriɔs blɔd kansa we dɛn kɔl akyu lukimiya.

Maylofibrosis we dɛn kɔl myelofibrosis

Dɛn kin tek dis as di kayn MPN we kin agresiv pas ɔl . insay maylofibrosis, yu bon mכro de mek stεm sεl dεm we nכ nכmal. dis sεl dεm kin inflamεd εn fכm ska tisu insay di bon mכro. As tɛm de go, di bon mɛro kin ful-ɔp wit dis ska tisu. afta dat di bon mכro nכ kin mek inof rεd bכdi sεl dεm igen fכ kכri כksijεn rawnd di bכdi. Dis kin mek yu gɛt anemia. Yu gɛt smɔl pletlɛt prodakshɔn bak. Sɔm pipul dɛm wae gɛt maylofibrosis kin gɛt akyu mayloid lukimiya (AML) bak.

Impɔtant Trombosaytemia

Essential thrombocythemia na wan kכndyushכn we yu bon mכro de mek tu mכch pletlet dεm.Fɔ mek. Nɔmal wan, we blɔd vesel bɔs, di pletlɛt dɛn kin gɛda togɛda fɔ mek wan klot ɛn stɔp di blɔd. Bɔt pan dis kɔndishɔn, dɛn kin mek pletlɛt dɛn na di bon mɛro fɔ natin. Dɛn ɛkstra pletlɛt ya kin mek blɔd klɔt ɛn i kin mek pɔsin gɛt at atak ɛn strok. Lɛk ɔda MPN dɛm, di sayn dɛm kin kam smɔl smɔl. Bɔrku pipul dɛn kin no se dɛn gɛt dis sik we dɛn kin du blɔd tɛst ɔltɛm sho se dɛn gɛt bɔku pletlɛt dɛn. Na sɔm pipul dɛm, de sik kin go bifo to lukimiya.

Ɔda kayn MPN dɛn de?

Yes, sɔm ɔda kayn MPN dɛn de. Sɔm pan dɛn na:

• Chronic eosinophilic leukemia (CEL): Dis na wan sik we de mek wan kayn wayt blɔd sɛl we dɛn kɔl eosinophil bɔku pasmak. Bɔku tɛm, i kin apin na di splin. Na smɔl tɛm nɔmɔ i kin go bifo to akyu mayloid lukimiya (AML). Dɛn kin kɔl dis bak haypareosinophilic syndrome.
• Chronic myelogenous leukemia (CML): Dis na wan kayn wayt blɔd sɛl we dɛn kɔl granulocytes we de prodyuz pasmak. Dɛn sɛl ya kin gɛda ɛn mek i nɔ izi fɔ mek di bon mɛro mek ɔda blɔd sɛl dɛn we nid.
• Chronic neutrophilic leukemia (CNL): Insay dis, dɛn kin mek wan kayn wayt blɔd sɛl we dɛn kɔl nyutrofil pasmak.
• Mayloproliferative neoplasm, unclassifiable (MPN-U): Dis na wan kayn MPN we nɔ fit insay ɛni wan pan di ɔda kategori dɛm. I kin mek difrɛn kayn blɔd sɛl dɛn lɛk wayt blɔd sɛl, rɛd blɔd sɛl, ɔ pletlɛt dɛn, bɔku pasmak.

Wetin na di sayn dɛm fɔ MPN?

We yu bigin, yu nɔ go gɛt ɛni sayn . As di sik de go bifo, yu kin notis sayn dɛm fɔ se yu splin dɔn swel (splenomegaly). di splin de na yu lεft say כnda yu rib dεm. I kin fil ful, i kin stif, ɛn i nɔ kin fil fayn. pan ɔl we dis swɛlin na di splin kin kɔmɔn fɔ bɔku kayn MPN, i nɔ kin kɔmɔn lɛk di impɔtant trombosaytemia.

Ɔda sayn dɛm kin difrɛn difrɛn wan bay di kayn MPN .

Kronik eosinofilik lukimiya (CEL) .

• Di sayn we kin apin mɔ na we pɔsin gɛt rɔsh na in skin .
• Yu kin fil taya ɛn yu kin fil fiva.
• Ɔda sayn dɛm de dipen pan di pat dɛm na yu bɔdi we yu gɛt di ay eosinophil lɛvɛl.

Kronik maylojenik lukimiya (CML) ɛn kronik nyutrofilik lukimiya (CNL) .

• Bɔn pen
• Nayt swet dɛn
• Fiva ɛn taya
• Brus izi wan
• I nɔ kin want fɔ it ɛn i nɔ kin gɛt bɔku bɔku bɔdi

Impɔtant trombosaytemia

• Brus izi wan
• Blɔd we de kɔmɔt na yu nos, yu mɔt, ɔ yu gɔm fɔ natin
• Blɔd we de kɔmɔt na di bɛlɛ ɔ di insay
• Blɔd we de na di urine

Polisaytemia vera

• Ed de at
• Diziz we pɔsin kin gɛt
• We pɔsin taya
• Blɔr vishɔn ɔ dabl vishɔn

Praymari maylofibrosis we de mek pɔsin gɛt sik

• Di sayn dɛm fɔ anemia (we yu taya, yu wik, yu nɔ de blo fayn) kin sho.
• Ɔda tin dɛn we dɛn kin du:
• Pale skin
• Nayt swet dɛn
• Fiva
• Skin we de it
• Fɔ it pasmak ɔ fɔ fil ful kwik kwik wan afta yu dɔn it (we yu satis kwik kwik wan) .
• We yu de lɔs yu wet
• Bɔn pen

Wetin kin mek pɔsin gɛt MPN?

כl di MPN kכndishכ n dεm na akwyayz jεnεtik dizכrd . Dis min se dɛn nɔ gɛt frɔm yu mama ɛn papa. Dɛn kin apin we chenj ɔ chenj apin na di jin dɛn we de kɔntrol di sɛl dɛn we de gro, ɛn dis kin mek di blɔd sɛl dɛn nɔ gro di rayt we.

Di wan dɛn we de stɔdi bɔt mɛrɛsin dɔn mek dɛn tin ya bɔt di jɛnɛtik muteshon we de mek MPN:

• Janus kinase (JAK) mכtεshכn: kכndyushכn lεk polycythemia vera, praymar myelofibrosis, εn εsεnsial trombocythemia kin kכz fכ mכtεshכn insay wan jin we dεn kכl Janus kinase 2 (JAK2) . Dis mכtεshכn kin mek di sεl dεm sheb we dεn nכ ebul fכ kכntrכl.
• mכtεshכn dεm na di MPL jin כ CALR jin: Pipul dεm we gεt εsεnsial trombocythemia εn praymar myelofibrosis kin gεt mכtεshכn na dεn MPL jin כ CALR jin.
• Kromozom mistek: Pipul dεm we gεt krכnik maylojen lukimiya (CML) gεt spεshal mistek na dεn kromozom (di strכkchכ we gεt jin dεm). insay CML, wan pat pan wan kromozom de swap wit כda kromozom, we de fכm wan "Philadelphia kromozom."

Pan ɔl we dɛn tin ya we dɛn dɔn fɛn nɔ ɛksplen gud gud wan wetin kin mek pɔsin chenj in jɛnɛtiks, dɛn kin ɛp dɔktɔ dɛn fɔ no if pɔsin gɛt sik dɛn ɛn mek tritmɛnt dɛn we go mek dɛn chenj dɛn jɛnɛtiks.

Wetin na di risk factor dɛm fɔ MPN?

Famili histri fɔ di sik (pan ɔl we dɛn sik ya na sik dɛn we dɛn kin gɛt, sɔm famili kin sho se dɛn gɛt dis sik), ej, ɛn man ɔ uman kin mek di risk fɔ gɛt MPN bɔku.

Risach pipul dεn dכn fכn bak se lεkshכn bitwin MPN εn εkspos to sכm tכxin εn rεdyushכn . Sɔm stɔdi dɛn sho se pipul dɛn we gɛt ay levul fɔ redyushɔn ɛn sɔm pɔyzin, lɛk bɛnzin, kin gɛt mɔ risk fɔ gɛt MPN, lɛk polycythemia vera, praymari myelofibrosis, ɛn chronic myelogenous leukemia.

Aw dɛn kin no MPN?

Yu dɔktɔ go aks bɔt yu sik ɛn wɛl bɔdi istri. Dɔn, dɛn go du fizik ɛgzam fɔ chɛk fɔ sayn dɛn fɔ MPN. Dɛn go tɛst yu blɔd ɛn bon mɛro fɔ no if yu gɛt di sik.

• Kɔmplit blɔd kɔnt (CBC): .Dis de mekɔp ɔl di kayn blɔd sɛl dɛn we yu gɛt. insay esεnsial trombosaytεmia, dεn de chεk di pletlet lεvεl dεm. Insay polycythemia vera, dɛn kin chɛk ɛmoglobin (wan prɔtin we de insay rɛd blɔd sɛl dɛn), ɛn bak di wayt blɔd sɛl ɛn pletlɛt lɛvɛl.
• Peripheral blood smear (PBS): Dis tεst kin luk fכ abnכmal shep dεm na di bכdi sεl dεm, we kin gi klyu fכ wan mεdikal kכndyushכn.
• Blɔd kemistri tɛst: Dɛn tin ya kin no di lɛvɛl we difrɛn kemikal dɛn (lɛk prɔtin, ɛnzaym, ɛn glukɔs) de na yu blɔd. Dɛn nɔmba ya kin gi klyu bɔt aw yu ɔgan dɛn de wok, we kin mek pipul dɛn sɔprayz fɔ gɛt MPN.
• Bon mכro bayopsi: Yu dכkta kin du bon mכro aspirash כn כ bon mכro bayopsi. Dis min se yu fɔ tek wan sɛmpul pan yu bon mɛrɔ ɛn chɛk am fɔ si if yu gɛt blɔd sɛl. Dɔn di mɛdikal patɔlɔjis dɛn kin chɛk di blɔd sɛl dɛn ɛn di tisu dɛn ɔnda maykroskɔp fɔ luk fɔ difrɛns bitwin di nɔmal ɛn di nɔmal sɛl dɛn. Dɛn go luk bak fɔ ɛni stεm sɛl we nɔr nכmal. dεn go luk bak fכ di kromozom chenj dεm εn כda jεnεtik abnכmaliti dεm we kin sho wan kayn MPN.
• Jɛnɛtik tɛst: Dɔktɔ dɛn kin chɛk yu blɔd sɛl dɛn fɔ si if ɛni chenj de na di jin dɛn we de afɛkt di we aw dɛn de mek blɔd sɛl.

Yu tink se MPN kin wɛl ɔltogɛda? Wetin na di tritmɛnt dɛn?

di onli kכretiv tritmεnt we de naw fכ dεn sik ya na allogeneic stεm sεl transplant . Bɔt i sɔri fɔ no se bɔku pipul dɛn nɔ kin ebul fɔ du dis stem sɛl transplant bikɔs na tin we nɔ izi ɛn we kin mek dɛn bɔdi wok tranga wan.

Yu dɔktɔ go gi yu tritmɛnt fɔ kɔntrol yu sik, fɔ ridyus yu blɔd sɛl, fɔ mek yu nɔ gɛt di sik, ɛn fɔ mek yu nɔ gɛt prɔblɛm dɛn. Sɔm tritmɛnt kin ivin put di sik na rɛmishɔn. Di tritmɛnt fɔ MPN kin difrɛn difrɛn wan bay di kayn we:

• Chronic eosinophilic leukemia (CEL): Yu dɔktɔ kin yuz kemotɛrapi, kɔtikosterɔyd, ɔ imyunotɛrapi fɔ mek yu eosinophil lɛvɛl go dɔŋ.
• Chronic myelogenous leukemia (CML): Di tritmɛnt we dɛn kin yuz mɔ na targeted therapy, we kin stɔp di sɛl dɛn fɔ bɔku we dɛn nɔ ebul fɔ kɔntrol. Ɔda tritmɛnt dɛn na kemotɛrapi, imyunotɛrapi, redyushɔn tɛrapi, ɛn stem sɛl transplant.
• Kronik nyutrofilik lukimiya (CNL): Di tritmɛnt kin inklud kemotɛrapi, imyunotɛrapi, ɛn transplant stem sɛl.
• Impɔtant trombosaytemia: .If yu nɔr gɛt di sik, yu dɔktɔ kin disayd fɔ wach yu sik gud gud wan instead fɔ gi yu tritmɛnt. If yu gɛt sɔm sayn dɛn, yu go nid fɔ tek tritmɛnt we go mek di sɛl dɛn nɔ bɔku we yu nɔ ebul fɔ kɔntrol. Yu kin nid fɔ tek mɛrɛsin bak fɔ mek yu nɔ gɛt bɔku blɔd ɔ fɔ mek yu bon mɛrɔ nɔ mek bɔku pletlɛt.
• Polycythemia vera: Phlebotomy na di tritmɛnt we dɛn kin yuz mɔ fɔ polycythemia vera. We yu de du dis, yu dɔktɔ go pul smɔl blɔd ɔltɛm (lɛk we dɛn de gi yu blɔd) fɔ mek yu blɔd nɔ bɔku ɛn fɔ pul di rɛd blɔd sɛl dɛn we pasmak. If yu gɛt sɔm sayn dɛm, dɛn kin gi yu targeted therapy fɔ stɔp di sɛl dɛm fɔ multiply out of control. Dɛn kin gi yu bak mɛrɛsin dɛn we de ridyus di risk fɔ mek yu blɔd klɔt (lɛk aspirin) ɔ mɛrɛsin dɛn we de ridyus di nɔmba fɔ di rɛd blɔd sɛl dɛn.
• Praymari maylofibrosis: If yu nɔr gɛt ɛni sayn, yu dɔktɔ kin disayd fɔ wach yu sik gud gud wan. Difrɛn we ɔ mɛrɛsin dɛn de we dɛn kin yuz fɔ mɛn anemia. Fɔ ɛgzampul, if yu bon mɛro nɔ de mek inof rɛd blɔd sɛl, yu go nid fɔ tek blɔd. Yu kin nid bak fɔ tek mɛrɛsin dɛn we de mek di bon mɛro wok fɔ mek i gɛt mɔ blɔd sɛl dɛn. Ɔda tritmɛnt dɛn na targeted therapy, kemotɛrapi, immunotherapy, radiation therapy, ɛn stem cell transplant.

Aw lɔŋ pɔsin we gɛt MPN kin liv?

Dis kin difrɛn bad bad wan frɔm wan pɔsin to ɔda pɔsin . Bɔrku tin kin afɛkt dis, lɛk di kayn MPN, aw dɛn kin no di sik kwik kwik wan, ɛn aw yu kin du wɛl to tritmɛnt. If dɛn de wach ɛn trit dɛn fayn, bɔku pipul dɛn kin liv fɔ bɔku ia . Nɔr wan prɔgnosis ɔr ɛkspɛkt autkam nɔr de fɔ dɛn kɔndishɔn ya. In jɛnɛral, bɔrku pipul dɛm wae dɛn no se gɛt MPN stil de alayv afta fayv ia.

di rεt fכ sכvayv fכ spεsifi k MPN tכp dεm na dεn wan ya:

• Chronic myelogenous leukemia (CML): Di rεt we de liv wit CML dɔn inkrεs bכku bikɔs ɔf di sakrifays we nyu tεrapi dεm we dεn tכk bכt. di fayv ia sכvayv rεt fכ CML na 90%.
• Krεse nyutrofilik lukimiya (CNL) εn polycythemia vera: Wit gud mεnejmεnt, bכku pipul dεm de liv avεj lεk 20 ia afta dεn no di sik.
• Essential thrombocythemia: Bɔrku pipul dɛn kin liv fɔ bɔrku ia wae dɛn de tek mɛrɛsin wae de mek dɛn nɔr gɛt prɔblɛm dɛn we kin mek dɛn layf de pan denja lɛk we blɔd kin klɔt.
• Praymari maylofibrosis: Bɔrku pipul dɛm wae gɛt praymari maylofibrosis de liv fayv to tɛn ia afta dɛn dɔn no se dɛn gɛt am.

If yu gɛt dis sik, aks yu dɔktɔ bɔt yu prɔgnosis. Na dεn wan dεm wae no כl di tin dεm wae de afekt prognosis. Ɛn di impɔtant tin na dat, dɛn no yu, yu ej, ɛn yu ɔl wɛl bɔdi, ɛn bak di risk factor dɛm wae de afɛkt di prɔgnosis.

Yu tink se dɛn sik ya kin kil pɔsin?

Dɛn tin ya nɔto sik dɛn we kin kil pɔsin fɔ dɛnsɛf , bɔt sɔm kayn MPN kin mek pɔsin gɛt prɔblɛm dɛn we kin mek pɔsin in layf de pan denja lɛk at atak ɛn strok.

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

MPN na wan kɔmpleks sik. Bɔrku tritmɛnt de fɔ yu, ɛn sɔmtɛm dɛn kin gɛt sɔm kayn sayd ɛfɛkt. Dɔn bak, bɔku prɔblɛm dɛn de we kin apin dipen pan yu kɔndishɔn. E fayn fɔ no us sayn dɛm wae yu fɔ no bɔt. Tɔk to yu dɔktɔ fɔ ɔndastand aw yu gɛt di sik ɛn fɔ disayd bɔt di tritmɛnt.

Sɔm kwɛstyɔn dɛn we yu kin aks:

• Wetin na di gol fɔ tritmɛnt (fɔ pul di sik, fɔ ridyus di sayn dɛm, fɔ mek i nɔ gɛt prɔblɛm, ɛn ɔda tin dɛm)?
• Wetin na di tritmɛnt dɛn we a kin gɛt?
• Wetin na di sayd ɛfɛkt dɛn we pɔsin kin gɛt we i gɛt tritmɛnt?
• Aw lɔng a go nid fɔ gɛt tritmɛnt fɔ mi sik?
• Aw ɔltɛm a go nid fɔ du tɛst (imajin ɔ blɔd wok) fɔ wach mi kɔndishɔn?
• Wetin na de sayn dɛm wae go ɛp mi fɔ no if mi sik de bɛtɛ ɔr de wɔs?
• Wetin na di sayn dɛm wae de wɔn mi bɔt wan kɔmplikeshɔn?
• Us kɔmplikɛshɔn dɛn we nid fɔ gɛt mɛrɛsin kwik kwik wan?
• Wetin na di prɔgnosis we dɛn kin ɛkspɛkt fɔ mi kɔndishɔn?
• Us chenj dɛn na mi layf yu kin advays fɔ kɔntrol mi kɔndishɔn ɛn di sayd ɛfɛkt dɛn we di tritmɛnt kin gɛt?

Aw a kin kia fɔ misɛf? (Sɔm impɔtant tin dɛn fɔ yu)

Fɔ liv wit MPN kin mek yu kɔnfyus smɔl sɔm tɛm. Yu kin de du wɛl ɛn nɔr de fil ɛni prɔblɛm, bɔt yu kin wɔnda if ɛnitin de we a go du fɔ mek a nɔ gɛt di sik. If yu de gɛt tritmɛnt, yu kin nid ɛp fɔ kɔntrol di sayd ɛfɛkt dɛm we di tritmɛnt kin gɛt ɛn di sayn dɛm. Bɔt, yu go gɛt fɔ liv wit dis sik fɔ bɔku ia we de kam. Na sɔm advays dɛn we go ɛp yu:

• Ɔndastand yu wɛl bɔdi kɔndishɔn: Bɔrku MPN simptom kin fiba ɔda, nɔr siriɔs sik. Sɔm sayn dɛm kin bi sayn dɛm bak fɔ siriɔs mɛrɛsin kɔmplikeshɔn. I kin tranga fɔ no di difrɛns, ɛn yu kin fil lɛk se yu de mis impɔtant tin dɛn fɔ no. Aks yu dɔktɔ fɔ ɛksplen aw dis sik kin afɛkt yu. We yu no wetin fɔ ɛkspɛkt, dat kin ɛp yu fɔ fil se yu gɛt kɔnfidɛns bɔt yu sik.
• Manej yu strɛs: Fɔ liv wit sik wae yu dɔn gɛt fɔ lɔng tɛm kin mek yu strɛs. If yu de fil fɔ wɔri bɔt yu sik, tɔk to yu dɔktɔ bɔt am. Dɛn kin ɛksplen wetin dɛn kin du fɔ ɛp yu naw ɛn wetin dɛn kin du fɔ ɛp yu tumara bambay.
• It fayn it we gɛt wɛlbɔdi:If yu it fayn, dat kin ɛp yu fɔ kɔntrol yu sik. Tɔk to pɔsin we sabi bɔt it if yu nid ɛp fɔ mek yu it fayn fayn wan.
• Gɛt sɔm ɛksesaiz: Ɛksesaiz na fayn we fɔ mek yu nɔ strɛs.
• Fɛn sɔpɔt: MPN na sik we nɔ kin bɔku. Sɔpɔt grup kin bi fayn we fɔ kɔnɛkt ɛn tɔk to pipul dɛn we no wetin yu de go tru.

Mɛmba se ivin wit dis kayn sik, yu kin liv gud layf bay we yu de no ɛn fala di advays dɛn we di dɔktɔ gi yu.

Ustɛm a fɔ go to dɔktɔ?

If yu gɛt MPN bɔt yu nɔ gɛt ɛni sayn, ɔ yu notis chenj na yu bɔdi we de sho se yu gɛt di sik, go to yu dɔktɔ wantɛm wantɛm.

MPN na akchuali wan bit of a misteri. Risach pipul dɛn no se MPN gɛt fɔ du wit abnɔmal blɔd sɛl dɛn we de gro. Dɛn no bak se dɛn na jɛnɛtik dizayd, bɔt dɛn stil nɔ no di rayt tin we kin mek di jɛnɛtik chenj dɛn we kin mek pɔsin gɛt MPN . Bikɔs dis na sik wae nɔr kin bɔrku, bɔrku pipul nɔr kin no aw e kin tan lɛk fɔ liv wit MPN. Bɔt dɔktɔ ɛn risecharch dɛn de lan mɔ bɔt MPN, mɔ bɔt mɔ fayn we fɔ mɛn di sik dɛn ɛn ridyus di risk fɔ siriɔs mɛrɛsin kɔmplikeshɔn. So, nɔ ɛva giv ɔp op .

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