Yu kidni dɛn de pul bɔku prɔtin? Lɛ wi tɔk bɔt Nephrotic Syndrome!

Yu leg, yu an, ɔ yu fes dɔn bigin fɔ swel wantɛm wantɛm? Ɔ yu urine tan lɛk pikin in bɔdi we de swel? I kin tan lɛk fom we yu de pis ? Dɛn tin ya kin bi smɔl prɔblɛm wit yu kidni dɛm, we kin bi bikɔs ɔf wan mɛrɛsin. Tide wi go tɔk bɔt wan pan dɛn kayn kidni sik ya, ‘Nephrotic Syndrome’. Nɔ wɔri, wi go tɔk bɔt dis simpul wan, di we we yu go ɔndastand.

Wetin na di sik we dɛn kɔl Nephrotic Syndrome?

Fɔ tɔk am simpul wan, nɛfrɔtik sindrom na wan sik we wi kidni dɛn kin pul bɔku bɔku prɔtin na di urine. Dɔktɔ dɛn kin kɔl dis ``proteinuria''. fכ bi prεsis, if dεn kכl mכr dan 3 gram protin (we hεvi sכm pas wan US pεni) insay di urine fכ wan de, dat na di men sayn fכ dis kכndyushכn. Dis na lɛk 20 tɛm pas di wan we di kidni dɛn we gɛt wɛlbɔdi kin pul kɔmɔt.

Naw tink bɔt wi kidni dɛn lɛk filta . dis filta gεt sכm sכm bכdi vεsul dεm, we wi kכl `(glomeruli)` . dis `(glomeruli)` dεm de filta di west prodakt dεm (fכ egzampl, naytrojen west `(urea)`, mכsul west `(creatinine)`, εn asid dεm), εn wata we nכ nid frכm di bכdi. Dɔn dɛn kin pul dɛn kɔmɔt lɛk urine. nכmal wan, insay hεlty kidni, di `(glomeruli)` de filta di tin dεm we di bכdi nid, lεk di protin dεm, εn kip dεm na di bכdi, spεshal wan di protin `(albumin)` . Bɔt we dɛn `(glomeruli)` ya dɔn pwɛl, dɛn nɔ de wok fayn. afta dat, valyu protin dεm lεk `(albumin)` kin kכmכt izi wan na di urine.

Yu tink se dis de mek pɔsin in layf de pan denja?

Yɛs, di sik we dɛn kɔl nephrotic syndrome na siriɔs sik . If yu nɔ trit yu fayn, i kin mek yu gɛt ɔda prɔblɛm dɛn ɛn ivin afɛkt yu layf. So, i rili impɔtant fɔ no bɔt dis ɛn go to dɔktɔ wantɛm wantɛm if yu gɛt sɔm sayn dɛn.

Udat kin gɛt di sik we dɛn kɔl nephrotic syndrome?

Ɛnibɔdi kin divɛlɔp dis. Bɔt pipul dɛm wae gɛt dis kayn kidni sik wae gɛt fɔ du wit dayabitis, wae gɛt sɔm kayn alɛji, ɛn wae gɛt dis kayn kidni sik na dɛn famili (wit nɛfrotik sindrom) kin gɛt dis sik.

Dis nɔto sik we bɔku pipul dɛn kin gɛt.

• I kin ambɔg lɛk 1 pan ɛvri 50,000 pikin dɛn ɛvri ia. Bɔku tɛm dɛn kin no am pan pikin dɛn we ol bitwin 2 ɛn 5. Bɔy pikin dɛn kin gɛt am tu tɛm pas gyal pikin dɛn.
• Na big pipul dɛm , dis kin apin to lɛk tri pan ɛvri ɔndrɛd tawzin pipul dɛm insay wan ia.

Aw di sik we dɛn kɔl nephrotic syndrome kin afɛkt di bɔdi?

We di prɔtin dɛn we rili impɔtant to wi bɔdi, kɔmɔt na di urine, difrɛn prɔblɛm dɛn kin kam.

• Sɔm prɔtin dɛn kin ɛp fɔ mek blɔd nɔ klot . We dɛn nɔ de, blɔd kin klɔt.
• Wan ɔda impɔtant kayn prɔtin na`(Imyunoglobulin dɛn)` . Dɛn tin ya kin ɛp wi imyun sistɛm fɔ fɛt sik ɛn infɛkshɔn. We dɛn tin ya nɔ de, i kin izi fɔ mek wi gɛt infɛkshɔn. Fɔ ɛgzampul:
• `(Nimonia)` (Nimonia)
• Sεlulayt (na wan baktri infεkshכn na di skin) .
• Pɛritonitis (na infεkshɔn na di layn na di bɛlɛ) .

Wetin na di sayn dɛm wae de sho se yu gɛt nefrotic syndrome?

I impɔtant fɔ pe atɛnshɔn gud wan to dɛn sayn ya:

• fכ gεt bכku protin `(albumin)` na di urine (`(albuminuria)`) : mכr dan 3.5 gram `(albumin)` protin de kכmכt fכ wan de.
• di fεt εn kכlestכl we de na di bכdi de bכku (hyperlipidemia) .
• Swel (`(edema)`) : Bɔku tɛm, di leg, anklɛ, ɛn fut kin swel. Sɔntɛnde, di an ɛn di fes kin swel bak. Imajin, if yu pikin wek na mɔnin ɛn di say we de rawnd in yay tan lɛk se i dɔn swel, dat kin bi sayn bak fɔ dis.
• di lεvεl dεm we di albumin protin de dכn na di bכdi (hypoalbuminemia) .
• Fɔd nɔ kin te .
• Fɔ fil se yu nɔ gɛt layf ɛn yu taya ɔltɛm .
• Bɛlɛ pen (ɛnisay frɔm di rib to di ɔda bɛlɛ).
• Foamy urine , lɛk wata we gɛt sop.

Wan ɔda tin na dat wi bɔdi kin lɔs impɔtant minral ɛn vaytamɛn dɛn, mɔ di kalsiɔm ɛn vaytamɛn D , dis we. Insay yɔŋ pikin dɛn, dis kin afɛkt di we aw dɛn de gro. di ia we de lכs, di nel dεm we wik, εn sik dεm we de mek yu bon wik lεk ``(Osteoporosis)`` (bon tinin sik) kin apin bak.

Wetin na di prɔblɛm dɛn we kin apin we pɔsin gɛt nɛfrɔtik sindrom?

If dɛn nɔ trit am, prɔblɛm dɛn lɛk:

• `(Acute kidney injury)` - Na kכndyushכn we di kidni dεm kin stכp fכ wok fayn wan wan.
• Anemia - Na di bכdi sεl dεm we de fכm we de kכri כksijεn to di bכdi in כgan dεm we nכ de.
• Koronari at sik - Fεt dεm we de na di at dεm we de gi bכdi to di at.
• haypatεnshכn - Bכdi prεshכn we hכy pas nכmal as i de travul tru di bכdi vεsul dεm.
• haypotayroydism - di tayroyd gland nכ de rilis inof tayroyd כmon insay di bכdi.

Wetin na de tin wae kin mek pɔrsin gɛt nefrotic syndrome?

כltεm, dεn `(glomeruli)` dεm ya kin pwεl bikoz fכ di sik dεm na di kidni. Dɔktɔ ɛn risach pipul dɛn stil nɔ shɔ wetin mek dɛn sik ya kin afɛkt di `(glomeruli)` dairekt wan. dis `(glomeruli)` dεm we dεn dכn pwεl na di mεn kכz fכ nεfrotik sεndrכm. Sɔm pan dɛn sik ya na:

• `(Amyloidosis)` : insay dis, wan kayn protin we dεn kכl amyloid de dכn insay wi imכtant כgan dεm. Bɔku tɛm dis kin apin na di kidni dɛn. afta dat di filta abiliti fכ di kidni dεm de dכn.
• `(Nɛfropati we gɛt fɔ du wit dayabitis)`Nεfropati: Dis na we di kidni dεm nכ de wok fayn. Dis kכndyushכn kin apin we dayabεtis de pwεl wan כ mכr pan di nεv dεm na di kidni dεm. Dis kin mek yu nɔ gɛt bɛtɛ trɛnk, yu mɔsul dɛn kin wik, ɛn yu kin fil pen.
• fכkal sεgmεnt glomerulosclerosis (FSGS) : dis de mek ska na sכm sכm pat dεm na di glomeruli. Dis kin mek yu swel, yu kidni nɔ de wok fayn, ɛn i kin mek yu gɛt prɔtin na di urine.
• Lupus : Lupus na sik we pɔsin kin gɛt we i de fɛt insɛf. I kin mek di bɔdi inflamɛns, swel, ɛn pen ɔlsay na di bɔdi. I kin afɛkt di kidni dɛn bak.
• Membranous nephropathy : insay dis, wi bכdi in כwn imyun sistεm de atak di filta mεmbran dεm na di kidni dεm.
• Minimal chenj sik (MCD) : Dis na wan kayn nεfropathy bak we di kidni dεm nכ de wok fayn fayn wan. Bɔt we dɛn tek di kidni bayɔpsi nɔ de sho ɛni big damej pan di glomeruli ɔ di kidni tisu. Pan ɔl we i kin apin ɛni ej, i kin apin mɔ pan yɔŋ pikin dɛn.

Aw dɛn kin no se pɔsin gɛt di sik we dɛn kɔl nephrotic syndrome?

Dɔktɔ dɛn kin du bɔku tɛst fɔ no if yu gɛt dis sik:

Urinalysis tɛst dɛn we dɛn kin du

Dɛn kin no dis bay we dɛn de chɛk yu urine, we de luk aw yu urine tan, di kemikal dɛn we de insay, ɛn aw yu urine de luk wit maykroskɔpik.

• Dipstik tɛst : Insay dis tɛst, yu kin pis insay spɛshal kɔntena na dɔktɔ in ɔfis ɔ ɔspitul. Dɔn, dɔktɔ ɔ nɔs kin put wan pepa we dɛn kɔt wit kemikal (dipstik) insay di kɔntena. If albumin de na yu urine, di strip go chenj in kɔlɔ.
• Yurin prɔtin tɛst : Dɛn kin du dɛn tɛst ya if dɛn nid fɔ mɛzhɔ mɔ kɔrɛkt wan.
• Wan singl urine sample : Dɛn kin sɛn dis to lab. Dɛn go luk aw bɔku `(albumin)` ɛn `(creatinine)` de na yu urine (`(albumin-to-creatinine ratio)`). If yu gɛt pas 30 miligram `(albumin)` pan wan gram `(creatinine)`, dat kin bi prɔblɛm.
• 24 awa urine collection : Di dɔktɔ go gi yu wan bɔtul fɔ gɛda yu urine na os. Di de we dɛn go du di tɛst:
• Fɔs tin na mɔnin, we yu wek, pis na tɔylɛt lɛk aw yu kin pis.
• Dɔn, pis insay da bɔtul de ɔl di de te yu go slip na nɛt.
• Di nɛks mɔnin, jɔs afta yu wek, pis insay di sem bɔtul fɔ di las tɛm.
• Dɔn yu fɔ kɛr da sampul de go na di dɔktɔ in ɔfis ɔ na di lab, usay dɛn kin jɔs mɛzhɔ di amɔnt fɔ `(albumin)`.

Blɔd tɛst dɛn

Insay dis, di dɔktɔ kin yuz wan tint nidul fɔ tek smɔl blɔd frɔm wan vein we de na yu an. Dɛn kin sɛn am na wan lab fɔ mek dɛn tɛst am. if di lכw lεvεl fכ `(albumin)` כ כda protin dεm de na di bכdi, i kin bi nεfrotik sεndrכm. dεn de chεk bak di lεvεl dεm fכ kכlestכl εn `(triglyceride)` na di bכdi. We `(albumin)` smɔl, dɛn tin ya kin bɔku.

Kidni bayɔpsi

We dɛn de du dis, di dɔktɔ kin tek wan smɔl pat pan yu kidni ɛn chɛk am wit maykroskɔp. Di eria de numb bifo di prosidur, so yu nɔ go fil ɛni pen. Dɛn kin gi yu smɔl mɛrɛsin bak fɔ slip fɔ ɛp yu fɔ rilaks. Dɔn di dɔktɔ kin put nidul tru yu skin insay yu kidni fɔ tek di tisu sɛmpul.

Bɔt if yu gɛt dayabitis ɛn yu dɔktɔ tink se yu gɛt nephrotic syndrome, bɔku tɛm i nɔ kin nid fɔ tek di kidni bayɔpsi. Yu mɛdikal histri, urine test, ɛn blɔd tɛst kin ɛp fɔ no if yu gɛt nefrotic syndrome we dayabitis kin mek yu gɛt.

Yu tink se dɛn kin mɛn di sik we dɛn kɔl nephrotic syndrome?

Dis nɔto sik we pɔsin kin mɛn ɔltogɛda . Bɔt gud nyus de! If i apin to yɔŋ pikin dɛm, bɔku tɛm i kin go bay di tɛm we dɛn yɔŋ, arawnd 18-20 ia.

Tritmɛnt kin kɔntrol di sayn dɛm ɛn stɔp mɔ damej pan di kidni dɛm.

Di tritmɛnt na fɔ trit di ɔndalayn kɔz, fɔ ridyus ay blɔd prɛshɔn, kɔlɔstrel, swel, ɛn di risk fɔ gɛt di sik. Bɔku tɛm, i kin gɛt fɔ du wit mɛrɛsin ɛn chenj di it dɛn we pɔsin de it .

• Sɔm mɛrɛsin wae de gi yu ay blɔd prɛshɔn kin ɛp fɔ kɔntrol di sik na yu kidni wae kin mek yu gɛt nefrotic syndrome. Fɔ ɛgzampul:
• `(Angiotensin-kכnvεrt εnzym (ACE) inhibito dεm)`
• `(Angiotensin rεsεptכr blכkεr dεm (ARBs))`
• Dɛn mɛrɛsin ya de ridyus di prɛshɔn we de insay di glomeruli ɛn ridyus di albumin we de kɔmɔt na di urine. Bɔku pipul dɛn kin nid tu ɔ tri mɛrɛsin fɔ kɔntrol dɛn blɔd prɛshɔn.
• Apat frɔm wan ACE inhibitor ɔ wan ARB, yu dɔktɔ kin gi yu wan diuretic . Diuretics de ɛp yu kidni fɔ pul di wata we pasmak na yu blɔd. Dɛn kin ɛp bak fɔ ridyus blɔd prɛshɔn ɛn swel. Ɔda mɛrɛsin dɛn we de mek blɔd prɛshɔn go dɔŋ na beta-blɔk ɛn kalsiɔm chanɛl blɔk .
• di dכkta kin gi yu ``statin`` mεdikeshכn fכ lכs kכlestכl.
• If yu gɛt nefrotic syndrome, i fayn bak fɔ gɛt di influenza (flu) vaysin ɛn di nyumococcal vaysin ɛvri ia. di nyumokok vaksin kin protεkt frכm infεkshכn dεm we baktri dεm we dεn kכl nyumokok (e.g. infεkshכn na di yes, nyumonia, mεningaytis).
• Sɔntɛnde, yu dɔktɔ kin gi yu mɛrɛsin we de mek yu blɔd tan (anticoagulants), bɔt dɛn kin gi yu dɛn tin ya if yu gɛt blɔd klɔt. Dɛn nɔ kin mek yu nɔ gɛt di sik we dɛn kɔl nephrotic syndrome ɔ di sayn dɛn we i kin gɛt.

Yu nid fɔ tek tɛm wit it ɛn drink?

Di it ɛn drink nɔ gɛt ɛni impɔtant ifɛkt pan di divɛlɔpmɛnt ɔ prɛvɛnshɔn fɔ di nɛfrɔtik sindrom pan big pipul dɛn. Bɔt if yu gɛt dis sik, .Sɔm sayn dɛn kin ridyus if yu chenj di it we yu de it.

• If yu ridyus sɔl (sɔdiɔm) na yu it, dat kin ɛp fɔ mek yu nɔ swel . Bɔku pan di sodium we de insay di it we wi de it kɔmɔt frɔm sɔl. If yu drink mɔ wata, dat kin ɛp bak fɔ mek yu nɔ swel.
• we yu ridyus di satεrayt fεt εn kכlestכl na yu it kin εp fכ kכntrכl ``hyperlipidemia'' (high bכdi fεt). I bɛtɛ fɔ lɛ yu nɔ it bɔku it dɛn lɛk tin dɛn we dɛn mek wit milk we gɛt ful fat, rɛd mit, mit we dɛn dɔn prosɛs, chiz, it dɛn we dɛn dɔn frɛsh, tin dɛn we dɛn dɔn bek, ɛn swit.

Aw a kin kia fɔ misɛf?

Di bɛst we fɔ kɔntrol yu sik dɛn na fɔ tek yu mɛrɛsin dɛn lɛk aw yu dɔktɔ tɛl yu . I fayn bak fɔ it it we gɛt bɔku potashɔm ɛn prɔtin, bɔt we nɔ gɛt bɔku sodium, sɛtyuret fat, ɛn kɔlɔstrel.

Aw kwik a go fil fayn afta dɛn dɔn trit mi?

Dis kin difrεn dipכnt pan di kכz fכ di nεfrotik sεndrכm. Sɔm pipul dɛn kin bigin fɔ fil fayn insay sɔm dez afta dɛn bigin fɔ trit dɛn. Fɔ ɔda pipul dɛn, i kin tek sɔm wik ɔ ivin sɔm mɔnt. I impɔtant fɔ peshɛnt.

Wetin kin apin to pɔsin we gɛt nefrotic syndrome?

If dɛn no di sik ɛn trit dɛn kɔrɛkt wan, pipul dɛn we gɛt nefrotik sindrom kin gɛt gud tin fɔ du . Mɔs pipul dɛn kin ansa fayn to tritmɛnt ɛn go insay rɛmishɔn (`(rɛmishɔn)`). Dis min se di sayn dɛm kin go. If yu bin gɛt nephrotic syndrome we yu bin smɔl, lɛk aw wi bin dɔn tɔk, i pɔsibul se i go dɔn kpatakpata we yu rich big pɔsin.

Yu tink se dɛn kin ebul fɔ avɔyd di sik we dɛn kɔl nephrotic syndrome?

Nephrotic syndrome nɔ kin ebul fɔ avɔyd , bɔt di rayt tritmɛnt fɔ di ɔndalayn kɔndishɔn dɛm we de mek i kam (e.g., dayabitis, ay blɔd prɛshɔn) ɛn chenj na di it kin ɛp fɔ mek di simptom dɛn bɛtɛ ɛn ridyus di damej pan di kidni dɛm.

Ustɛm yu fɔ go to dɔktɔ?

If yu gɛt sayn dɛn fɔ sik na yu kidni, mɔ yu urine we gɛt fom ɛn swɛlin, we kin las fɔ pas sɔm dez, go to dɔktɔ wantɛm wantɛm . Di kwik we dɛn no am, na di mɔ i izi fɔ trit.

Us kwɛstyɔn dɛn yu fɔ aks di dɔktɔ?

Yu kin aks dɛn kwɛstyɔn ya we yu go to dɔktɔ:

• "Aw yu no se a gɛt nɛfrɔtik sindrom?"
• "A nid fɔ du ɛni ɔda tɛst fɔ kɔnfɔm yu diagnosis?"
• "If a nɔ gɛt nefrotik sindrom, us ɔda kɔndishɔn a go gɛt?"
• "Us kɔndishɔn mek a gɛt nɛfrɔtik sindrom?"
• "Yu tink se mi nɛfrɔtik sindrom go go insay rɛmishɔn wit tritmɛnt?"
• "Mi pikin in nefrotik sindrom go go as i de gro?"
• "Us mɛrɛsin ɔ tritmɛnt yu kin advays?"
• "A nid fɔ mek ɛni chenj to mi it?"

Difrɛns bitwin Nɛfrɔtik Sindrom ɛn Nɛfritik Sindrom

Dɛn tu tin ya na tin dɛn we kin afɛkt di kidni dɛn.

• di men sayn fכ nεfrotik sεndrכ m na bכku protin na di urine.
• Di men sayn fɔ di nephritic syndrome na di inflamɛns na di kidni dɛm. Bɔrku tɛm, dis inflamɛns kin kam bikɔs ɔf infekshɔn, blɔd vesel sik, ɔr degeneration.

Difrɛns bitwin Nɛfrɔtik Sindrom ɛn Glomerulonephritis

Glomerulonephritis na sik bak na di kidni. Di sayn dɛm we i kin gɛt tan lɛk di sik we dɛn kɔl nephrotic syndrome. Bɔt di men difrɛns na di bɔku bɔku prɔtin we de kɔmɔt na di bɔdi .

• If yu gɛt nɛfrɔtik sindrom, yu kin pul pas 3.5 gram prɔtin fɔ wan de.
• If yu gɛt Glomerulonephritis, i nɔ rich 3.5 gram prɔtin we de kɔmɔt na di bɔdi ɛvride.

Wetin na di sik we dɛn kɔl congenital nephrotic syndrome?

Dis na wan sik we de apin we dɛn bɔn am . I kin mek yu kidni nɔ wok fayn fɔ ɔltɛm, bɔku tɛm na bitwin 2 ɛn 8. Dis na sik we pɔsin kin gɛt frɔm in kidni. Dat min se i kin pas frɔm mama ɛn papa to pikin dɛn.

Fɔ dɔn, tin dɛn fɔ mek yu mɛmba (Take-Home Message) .

so, fכ sכt, nεfrotik sεndrכm na wan kכndyushכn we di kidni dεm de kכl tu mכch protin na di urine. If yu gɛt sɔm sayn dɛn lɛk bɛlɛ pen, yu de urine we gɛt fom, yu de swel, yu nɔ de want fɔ it, ɛn yu de taya ɔltɛm we de las fɔ pas sɔm dez, i go fayn fɔ mek yu go to dɔktɔ. Mɛmba se if yu no yu kidni kwik kwik wan ɛn trit yu, dat kin ɛp fɔ mek yu kidni dɛn gɛt wɛlbɔdi ɛn fɔ mek yu nɔ gɛt siriɔs prɔblɛm dɛn . Nɔ panik, jɔs fala wetin yu dɔktɔ tɛl yu fɔ du. A de wish yu fɔ wɛl kwik kwik wan!

` Nεfrotik Sεndrכm, Kidni Sindrכm, Protεin, Swεl, Yurin Tεst, Pikin dεm, Nεfrotik Sεndrכm