Lɛ wi lan bɔt Paratayroyd Kansa. Nɔ fred, lɛ wi tɔk!

Wi ɔl kin gɛt smɔl chenj ɛn tin dɛn we nɔ kin izi fɔ wi bɔdi wan wan tɛm, nɔto so? Sɔntɛm na smɔl smɔl tin na yu nɛk, ɔ i kin bi sɔntin lɛk fɔ fil taya fɔ natin, ɔ fɔ fil tɔsti ɔltɛm. Pan ɔl we bɔku pan dɛn tin ya nɔto sɔntin we pɔsin fɔ wɔri bɔt, nɔto so i kin bi di men sayn dɛn we de sho se pɔsin gɛt sik. Tide wi go tɔk bɔt wan kayn kansa we nɔ kin bɔku, bɔt i rili impɔtant fɔ mek wi ɔl no bɔt. Dat na kansa we de divεlכp na di paratayroyd gland dεm, we dεn kכl mεdikal kεnsar paratayroyd kεnsar , כ `(Parathyroid Carcinoma)`.

Wetin na Paratayroyd Kansa?

Fɔ tɔk am simpul wan, paratayroyd kansa na wan kayn kansa we nɔ kin bɔku ɛn we kin kam na di tisu dɛn na yu paratayroyd gland dɛn. Yu paratayroyd gland dɛn kin de biɛn di tayroyd gland we shep lɛk bɔtaflay we de bifo yu nɛk.

Paratayroyd kansa dεn nכ de kכl fכ stej dεm (di ``fo stej neming sistεm``) lεk כda kayn kεnsar dεm. Bifo dat, dɔktɔ dɛn kin sheb di kansa to tri men kayn:

• Localized: Dis min se di kansa de na yu paratayroyd gland nɔmɔ. Sɔntɛnde, i kin dɔn spre smɔl to di tisu we de rawnd am. Dis min se di kansa stil de na wan eria.
• Metastatic: Dis na we di kansa dɔn spre to ɔda pat dɛn na yu bɔdi, lɛk di limf no dɛm, liva, lɔng, bon, ɔ pankrias. Bitwin 10% ɛn 30% pan di pipul dɛm wae gɛt paratayroyd kansa gɛt di kansa we de skata (mɛtastatik) di tɛm we dɛn no di sik. di say dεm we kin kכmכn pas כl na di lכng, bon, כ liva.
• Rikɔrɛnt: Dis na we di kansa de kam bak afta di fɔs tritmɛnt – bɔku tɛm afta dɛn dɔn ɔpreshɔn di kansa gland. Mɔr pas af pan pipul dɛm wae gɛt paratayroyd kansa go gɛt dis kayn kansa. Bɔku tɛm, di kansa kin kam bak insay tu to fayv ia afta dɛn du di fɔs ɔpreshɔn. Bɔt sɔntɛnde, i kin kam bak lɛk 20 ia.

Wetin na dɛn paratayrɔyd gland ya?

Bɔku pan wi gɛt 4 paratayroyd gland dɛn we gɛt sayz lɛk pis. As wi bin dɔn tɔk, dɛn tin ya de biɛn di tayroyd gland. lεk di tayroyd gland, di paratayroyd gland dεm na pat pan yu εndokrin sistεm. Sɔntɛnde, dɛn paratayroyd gland ya kin de nia yu εsophagus ɔ ivin na yu chɛst. Dɛn kɔl dis ɛktɔpik.di paratayroyd gland dεm dεn kכl dεm paratayroyd gland dεm, we min se dεn nכ de usay dεn fכ de nכmal.

Di men wok we yu paratayroyd gland dɛn de du na fɔ kɔntrol di kayn kalsiɔm we de na yu blɔd bay we dɛn de mek paratayroyd ɔmon (PTH) . Sɔntɛnde, wan ɔ mɔ pan yu paratayroyd gland dɛn kin bigin fɔ mek tumɔs pan dis paratayroyd ɔmon (PTH). Dɛn kɔl dis sik Primary Hyperparathyroidism (pHPT) . We dɛn mek tumɔs PTH, di kalsiɔm lɛvɛl na yu blɔd de go ɔp. Dɛn kɔl dis sik we dɛn kɔl haypa kalsiɔm .

Wetin na di difrɛns bitwin paratayroyd kansa ɛn paratayroyd adenoma?

Paratayroyd adenoma na wan fayn fayn tin we nɔ de mek kansa na di paratayroyd gland. Bɔt paratayrɔyd kansa na di divɛlɔpmɛnt fɔ di bad bad sɛl dɛn we nɔ gɛt kansa na yu paratayroyd tisu. Fɔ di sik dɛm we gɛt fɔ du wit di paratayroyd gland dɛm, paratayroyd adenoma kin bɔku pas paratayroyd kansa.

Bɔt dis na di impɔtant tin: Insay dɛn tu kɔndishɔn ya, paratayroyd kansa ɛn paratayroyd adenoma, yu paratayroyd gland kin wok pasmak ɛn mek tumɔs paratayroyd ɔmon (PTH). Dɔn, lɛk aw wi bin dɔn tɔk, aypa kalsiɔm kin apin. Dis aypa kalsiɔm kin ambɔg yu bɔdi ɛn yu wɛlbɔdi. So, di tritmɛnt we dɛn kin yuz mɔ fɔ paratayrɔyd kansa, ɛn bak fɔ paratayrɔyd adenoma, na fɔ ɔpreshɔn fɔ pul di paratayroyd gland we de wok pasmak.

Ivin fɔ dɔktɔ dɛn, i kin at fɔ no wantɛm if na paratayroyd adenoma ɔ paratayroyd kansa. biכs di sεl dεm fכ dεn tu kin luk sכm kayn we, afta dεn dכn כpכt di כva aktiv paratayroyd gland, dεn nid fכ du mכr tεst fכ kכnfכm if na adenoma כ na kansa.

Wetin na aypa kalsiɔm? Aw i gɛt fɔ du wit paratayrɔyd kansa?

Hypercalcemia na we yu blɔd kalsiɔm lɛvɛl pas aw i fɔ bi. Bɔku tɛm, pipul dɛn we gɛt paratayroyd kansa kin gɛt aypa kalsiɔm. Dis na bikɔs di kansa de mek yu paratayrɔyd gland de wok pasmak ɛn mek tumɔs paratayroyd ɔmon (PTH). Paratayroyd ɔmon (PTH) de mek di kayn kalsiɔm we de na yu blɔd bɛtɛ. So, if yu gɛt tumɔs paratayroyd ɔmon (PTH), yu blɔd kalsiɔm go bɔku.

Hypercalcemia kin ambɔg yu wɛl bɔdi ɛn bɔdi. So, i rili impɔtant fɔ trit di aypa kalsiɔm we di paratayroyd kansa kin mek ɛn bak di kansa insɛf.

Difrɛn kayn paratayrɔyd kansa de?

Yɛs, tu men kayn paratayrɔyd kansa de.

1. Di kayn we we kɔmɔn pas ɔl: Insay dis kes, di kansa sɛl dɛn kin mek yu paratayrɔyd gland mek tumɔs paratayroyd ɔmon (PTH) ɛn pul am na di blɔd. Dis kin mek di kalsiɔm lɛvɛl na yu blɔd go ɔp.

2. paratayroyd kansa we nכ de wok: dεn kכl dis bak ``paratayroyd kansa we nכ de sekret''. Dis difrɛn frɔm di ɔda kayn dɛn. Bikɔs, pipul dɛn we gɛt dis kayn kansa nɔ kin gɛt bɔku bɔku paratayrɔyd ɔmon (PTH) ɔ kalsiɔm na dɛn blɔd. Dis kayn tin nɔ kin apin so ɔltɛm, i kin apin to less dan 10% pan di wan dɛn we gɛt paratayroyd kansa.

We dɛn dɔn no se i gɛt paratayrɔyd kansa, dɛn kin du ɔda tɛst fɔ no if i de na di say we i de , if i de go ɔlsay , ɔ if i de kam bak . As wi bin dɔn tɔk, dɛn nɔ de yuz di 4 stej klasification we dɛn kin yuz fɔ ɔda kansa dɛn fɔ dis.

Udat dɛn kin gɛt paratayrɔyd kansa?

Dis kansa kin afɛkt uman ɛn man ikwal. Dɛn kin si am pan pipul dɛn we dɔn pas 30 ia .

Aw dis sik kin bɔku?

Paratayroyd kansa na sik we nɔ kin bɔku. Jɔs tink, i jɔs de mek 0.005% pan ɔl di kansa dɛn. Dɔn bak, paratayroyd kansa de mek bitwin 0.5% ɛn 1% pan ɔl di sik dɛn we gɛt fɔ du wit paratayroyd gland. So, dis na rili rare.

Wetin na di tin dɛn we kin mek pɔsin gɛt Paratayroyd Kansa?

Infakt, dɛn nɔ dɔn fɛn ɛni patikyula tin we kin mek pɔsin gɛt paratayrɔyd kansa yet.

כltu, dεn kin tek dεn jεnεtik (i.e., we dεn gεt frכm famili) kכndyushכn dεm as risk fכ dis kεnsar:

• Mכltipכl εndokrin niכplasia tayp I (MEN1) .
• Famili aysolεt haypaparatayroydism (FIHP) .
• Haypaparatayroydism-jaw tumor sindrom

Apat frɔm dat, if yu dɔn gɛt redyushɔn tɛrapi na yu ed ɔ yu nɛk trade, i kin mek yu gɛt paratayrɔyd kansa bak.

Wetin na di sayn dɛm fɔ Paratayroyd Kansa?

Bɔrku tɛm, di sayn dɛm fɔ paratayroyd kansa na di sayn dɛm fɔ haypa kalsiɔm we kin kɔmɔt. Di sayn dɛm ɛn sayn dɛm fɔ aypa kalsiɔm kin bi:

• Nid fɔ pis bɔku tɛm pas aw i kin pis (fɔ pis bɔku tɛm) .
• Fɔ fil se yu tɔsti pas aw yu kin fil
• Nɔs ɛn vɔmit
• As yu kin du amNɔto fɔ fil angri
• Banbɛlɛ
• Fɔ fil se yu taya bad bad wan
• Fɔ fil lɛk se yu at pwɛl
• Fɔgɛt fɔgɛt ɔ fɔ mɛmba tin
• Mɔsul dɛn de pen, wik, ɛn/ɔ limp

Ɔda sayn dɛn we kin sho se pɔsin gɛt paratayroyd kansa:

• Fɔ gɛt wan lump na yu nɛk
• Voys de chenj ɔ i de ala lawd lawd wan
• I nɔ izi fɔ swɛla it

If yu gɛt wan ɔr mɔr pan dɛn sik ya, nɔr frayd fɔ tink se na paratayroyd kansa fɔ tru. Dɛn kin si dɛn sayn ya bak pan bɔrku ɔda sik dɛm. Bɔt if sɔntin lɛk dis kɔntinyu, i go fayn fɔ mek yu go to dɔktɔ fɔ advays.

Aw dɛn kin no se pɔsin gɛt Paratayroyd Kansa?

Sɔntɛnde, fɔ no if yu gɛt paratayroyd kansa kin tranga smɔl. Wan rizin na dat di sɛl dɛn na wan paratayroyd adenoma we nɔ gɛt kansa ɛn di wan dɛn we gɛt paratayroyd kansa kin luk di sem.

Bɔku tɛm dɛn kin no se yu gɛt paratayroyd kansa afta dɛn dɔn ɔspitul yu abnɔmal, ɔva aktiv paratayroyd gland (a `parathyroidectomy`), ɛn dɛn kin chɛk di tisu mɔ. Sɔntɛnde, di dɔktɔ we de du di ɔpreshɔn kin no se pɔsin gɛt paratayrɔyd kansa we dɛn de du di ɔpreshɔn.

Us tɛst dɛn kin du fɔ no if pɔsin gɛt di sik?

As wi bin dɔn tɔk, bɔku tɛm dɛn kin no se yu gɛt paratayroyd kansa afta dɛn dɔn no se yu gɛt praymari haypaparatayroyd , ɛn dɛn kin ɔpreshɔn di paratayroyd gland we nɔrmal ɛn we de wok pasmak. Sɔntɛnde, di dɔktɔ we de du di ɔpreshɔn kin no se i gɛt paratayrɔyd kansa we dɛn de du di ɔpreshɔn.

Bifo dɛn du yu ɔpreshɔn fɔ pul yu haypa aktif paratayrɔyd gland, yu kin gɛt tɛst dɛn lɛk dɛn wan ya:

• Blɔd kalsiɔm tɛst
• Blɔd PTH tɛst
• Paratayroyd skan - Dis kin bi redioaktiv sestamibi skan ɛn/ɔ CT skan.

If dɛn no se yu gɛt paratayroyd kansa, yu dɔktɔ kin ɔda fɔ mek dɛn du imej tɛst lɛk dɛn wan ya fɔ si if di kansa dɔn skata (metastasized) to ɔda pat dɛn na yu bɔdi:

• CT skan (kɔmpyuta tomografi skan): CT skan de yuz X-ray ɛn kɔmpyuta fɔ mek bɔku tri-dimɛnshɔnal (3D) pikchɔ dɛn bɔt yu bɔdi.
• MRI skan (MRI - magnɛtik rɛsɔnans imej):MRI skan de yuz big magnet, redio wev, ɛn kɔmpyuta fɔ mek ditayli pikchɔ dɛn bɔt yu bɔdi. I nɔ de yuz X-ray (rɛdyushɔn).

Wetin na di tritmɛnt fɔ paratayrɔyd kansa?

di men tritmεnt opshכn fכ paratayroyd kεnsar na כpεrayshכn fכ pul di kansa paratayroyd gland (`en bloc resection`). If paratayrɔyd kansa dɔn skata (we dɔn mɛtastasayz), yu dɔktɔ kin nid bak fɔ pul di tisu dɛn we de rawnd yu paratayrɔyd gland ɔ kansa tisu frɔm ɔda pat dɛn na yu bɔdi.

Dɛn kin yuz dɛn ɔpreshɔn tɛknik ya fɔ paratayrɔyd kansa:

• En bloc resection: Insay dis prosidur, di sajin de pul yu ɔl paratayroyd gland ɛn di kapsul we de rawnd am. Sɔntɛnde, dɛn kin pul af pan di tayroyd gland bak we de na di sem say wit di paratayroyd gland we gɛt kansa, wit di tisu, mɔsul, ɛn nɛv dɛn we de rawnd am.
• Tumor debulking: Insay dis prosidur, di ɔspitul kin pul bɔku pan di tumor as i pɔsibul. Sɔm tumbu dɛn nɔ kin kɔmɔt kpatakpata.
• Metastasectomy: Insay dis, di ɔspitul kin pul ɛni kansa we dɔn spre (metastasized) to ɔda tisu ɛn/ɔ ɔgan dɛn na yu bɔdi, fɔ ɛgzampul, di lɔng dɛn.

A go gɛt kemotɛrapi ɔ redyushɔn tɛrapi?

Dɛn nɔ kin yuz kemotɛrapi ɛn redyushɔn tɛrapi fɔ mɛn paratayrɔyd kansa. Yu dɔktɔ go disayd if kemotɛrapi ɛn/ɔ redyushɔn tɛrapi na fayn tin fɔ yu.

Yu tink se mɛrɛsin de fɔ paratayrɔyd kansa?

Naw, no patikyula mɛrɛsin nɔ de fɔ paratayrɔyd kansa. Bɔrku pipul dɛm wae gɛt paratayroyd kansa kin gɛt sayn dɛm wae de sho se dɛn gɛt aypa kalsiɔm. Bikɔs aypa kalsiɔm kin ambɔg yu, yu dɔktɔ kin gi yu wan ɔ mɔ pan dɛn mɛrɛsin ya we de mek yu gɛt aypa kalsiɔm:

• Sinakalsεt (Sinakalsεt - Sεnsipar®) .
• Bisfosfonat dɛn
• Denosumab (Denosumab - XGEVA®) we de na di bɔdi.

If yu gɛt siriɔs sayn fɔ aypa kalsiɔm, yu dɔktɔ kin tɛl yu fɔ go na ɔspitul wantɛm wantɛm ɛn bigin fɔ gi yu wata we de insay yu bɛlɛ (IV) ɛn ɔda tritmɛnt dɛn.

Mi paratayrɔyd kansa kin kam bak?

Yɛs, pas af pan di pipul dɛn we dɛn kin no se gɛt paratayrɔyd kansa kin gɛt di kansa bak.Kansa kin kam bak insay sɔm ia – bɔku tɛm bitwin tu ɛn fayv ia. Bɔt sɔm tɛm, i kin apin bɔku bɔku ia (20 ia ɔ mɔ) afta dɛn dɔn no bɔt yu fɔs ɛn tritmɛnt.

Dis kansa kin spre (metastasize) to ɔda pat dɛm na di bɔdi?

Yes, paratayroyd kansa kin spre (metastasize) to ɔda pat dɛm na yu bɔdi. Bitwin 10% ɛn 30% pan di pipul dɛm wae gɛt paratayroyd kansa gɛt di kansa dɔn ɔlrɛdi skata (metastatic) di tɛm wae dɛn no di sik. Insay dɛn kayn tin ya, di kansa kin pas to yu lɔng, bon, ɔr liva. Bɔt i kin go bak to yu limf no ɔ pankrias.

Wetin na di prɔgnosis fɔ paratayrɔyd kansa?

Di prɔgnosis fɔ paratayroyd kansa dipen pan aw di ɔpreshɔn fɔ pul di paratayroyd gland kɔmplit we dɛn fɔs no se yu gɛt am, bikɔs sɛkɔndari tritmɛnt opshɔn dɛn lɛk redyushɔn tɛrapi ɛn kemotɛrapi nɔ bɔku.

Fɔ pipul dɛm we gɛt paratayroyd kansa we dɔn du en blok rɛsekshɔn ɛn we gɛt nɛgitiv margin, di rεt fɔ liv de rich 90% fayv ia afta di fɔs ɔpreshɔn. di rεt fכ sכvayv de hכy bak lεk 67% tεn ia afta di fכs כpεrayshכn.

Mɔ pas af pan di pipul dɛn we dɛn no se gɛt paratayroyd kansa ɛn we dɛn du ɔpreshɔn fɔ pul di gland go gɛt di kansa bak. Insay dɛn kayn tin ya, di kansa kin kam bak insay tu to fayv ia afta di fɔs ɔpreshɔn. Bɔt, i kin kam bak bɔku bɔku ia afta dat.

Yu tink se dɛn kin ebul fɔ avɔyd Paratayroyd Kansa?

Bɔt i sɔri fɔ no se, no we nɔ de we dɛn no fɔ mek yu nɔ gɛt paratayrɔyd kansa. Dɔn bak, no we nɔ de fɔ ridyus di risk fɔ gɛt dis sik. If ɛnibɔdi na yu famili dɔn gɛt paratayrɔyd gland, i fayn fɔ tɔk to yu dɔktɔ.

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

If yu gɛt paratayrɔyd kansa, yu kin aks yu dɔktɔ kwɛstyɔn dɛn lɛk dɛn wan ya:

• Di kansa dɔn skata pas mi paratayrɔyd gland?
• Wetin na di bɛst tritmɛnt fɔ paratayrɔyd kansa?
• Wetin na de risk ɛn sayd ɛfɛkt dɛm wae de tritmɛnt kin gɛt?
• Mi famili de pan denja fɔ gɛt paratayrɔyd kansa?
• A kin gɛt paratayrɔyd kansa bak?
• A de pan denja fɔ gɛt ɔda kayn kansa?
• Us fɔlɔp kia a go nid afta tritmɛnt?
• A fɔ no bɔt di sayn dɛn we de sho se a gɛt prɔblɛm dɛn?

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

If dɛn no se yu gɛt kansa, dat kin mek yu fred. Bɔt mɛmba se, .Yu mɛdikal tim de ya fɔ ɛp yu ɛn sho yu di bɛst tritmɛnt. Pan ɔl we naw, ɔpreshɔn na di wangren tritmɛnt fɔ paratayrɔyd kansa, risach ɛn tritmɛnt fɔ kansa de go bifo ɔltɛm. I kin ivin gɛt klinik trial we yu kin tek pat pan.So, nɔ fred fɔ aks yu dɔktɔ kwɛstyɔn bɔt yu paratayroyd kansa. Mek shɔ se dɛn ɛksplen ɔltin di we we yu ɔndastand.

` Paratayroyd Kansa, Paratayroyd Gland dɛm, Haypakalsiemia, Paratayroyd Ɔmon, PTH, Kansa Simptom dɛm, Kansa Tritmɛnt, Ɔpreshɔn