Yu no bɔt dis kansa we nɔ kin bɔku we kin apin na di layn na di bɛlɛ (peritoneal mesothelioma)?

Sɔntɛnde yu kin fil pen ɔ blo na yu bɛlɛ we nɔ klia? Yu kin fil se yu nɔ want fɔ it ɛn yu nɔ de gɛt bɔku bɔku bɔdi? Pan ɔl we sɔntɛnde wi nɔ kin pe atɛnshɔn to dɛn sayn ya, dɛn kin bi sayn fɔ wan siriɔs sik we de ɔnda dis sik. Tide wi go tɔk bɔt wan kayn kansa we nɔ kin bɔku, bɔt i fɔ gɛt bɔku atɛnshɔn. Dat na kansa we dɛn kɔl `Peritoneal Mesothelioma`.

Wetin na dis Pɛritonial Mɛsotelioma?

fכ simpul wan, `Peritoneal Mesothelioma` na kεnsar we de divεlכp insay wi bεlε, dat na, insay di tכn mεmbran we de kכba di bכdi, fכ mεdikal tεm, `peritoneum`. tink bɔt am, dis `peritoneum` lεk wan dilik protεktiv kכba rawnd imכtant כgan dεm insay wi bεlε, lεk di liva, intestinal, εn bεlε.

Dis kansa, lɛk ɔda kayn mɛsotelioma, kin gɛt fɔ du wit wan tin we dɛn kɔl asbest bifo tɛm. Yu go dɔn yɛri se asbest na tin we dɛn kin yuz fɔ mek sɔm tin dɛn fɔ bil. I rili denja bikɔs di fayv dɛn we de insay kin mek yu gɛt siriɔs prɔblɛm if yu blo dɛn ɔ it dɛn.

Pɛritonial mɛsotelioma na kansa we nɔ kin rili bad ɛn we kin skata kwik kwik wan. Bɔku tɛm, ivin we dɛn no se di kansa dɔn ɔlrɛdi skata ɔlsay na di layn na di bɛlɛ. So, i nɔ kin izi fɔ no am kwik kwik wan.

Wetin na di difrɛns bitwin Pɛritonial Mɛsotelioma ɛn Pleural Mɛsotelioma?

כl tu di `Peritoneal Mesothelioma` εn `Pleural Mesothelioma` de divεlכp insay di mεmbran dεm we de layn di imכtant kכva dεm εn di intanεt כgan dεm na wi bכdi.

• di pεritonεal mεsotelioma de divεlכp insay di mεmbran we de layn di bכdi kכva εn de rawnd di bכdi כgan dεm, dat na di pεritoneal we wi bin tכk bכt.
• di pleura mesothelioma de divεlכp na di mεmbran we de layn di chεst kεviti, spεshal wan di lכng dεm. Dɛn kɔl am di pleura.

dεn tu mεmbran dεm ya na wan spεshal tכp sεl we dεn kכl `mεsotelial sεl dεm`. Na dat mek dɛn kɔl dis kansa `mesothelioma`.

Dɛn tu kayn mɛsotelioma kin gɛt bad bad sik, we min se dɛn gɛt kansa . dis malignant mesothelial sel dεm de gro kwik kwik wan εn we dεn nכ de kכntro, we de pwεl di hεlty tisu we de rawnd. Pleural mesothelioma na wan kayn kansa we kכmכn pas di pεritoneal mesothelioma.

Udat kin gɛt dis sik pas ɔlman? Aw i kɔmɔn?

Ɛnibɔdi kin gɛt `Peritoneal Mesothelioma`. Bɔt i nɔ kin apin so ɔltɛm pan yɔŋ pikin dɛn. Bɔrku tɛm, dɛn kin no dis sik pan pipul dɛm wae dɔn pas 50 ia.

pan ɔl we `Peritoneal Mesothelioma` na di sɛkɔn kayn `Mesothelioma` (di fɔs wan na `Pleural Mesothelioma`), i kin bi bak wan kansa we nɔ kin bɔku. `Peritoneal Mesothelioma` de divεlכp bitwin 10% εn 20% pan כl di `Mesothelioma` pasεnshכn dεm. Imajin, na kɔntri lɛk Amɛrika, na bitwin 400 ɛn 1000 nyu kes dɛm nɔmɔ dɛn kin ripɔt ɛvri ia. So, pan ɔl we dɛn sik pipul ya kin de na Sri Lanka bak, di nɔmba rili smɔl.

Wetin na di sayn dɛm fɔ Pɛritonial Mɛsotelioma? Aw fɔ no dɛn?

Dis na rili impɔtant pɔynt bikɔs bɔku tɛm, Pɛritonial Mɛsotelioma nɔ kin sho ɛni simptom na di fɔs stej. Di sayn dɛm kin jɔs bigin fɔ sho afta di kansa dɔn skata to di ɔgan dɛm na di bɛlɛ.

Di sayn we kin apin mɔ na we wata kin bɔku na di bɛlɛ. Dɛn kin kɔl dis bak `ascites`. We di wata bɔku, di bɛlɛ kin bigin fɔ big ɛn swel. Di sɛkɔn sayn we kin apin mɔ na di bɛlɛ pen.

Ɔda sayn dɛn kin bi:

• Ascites : I kin fil lɛk se di bɛlɛ ful ɛn ebi.
• Bεlε kin swel ɔ blo : Klos kin tayt.
• Bɛlɛ pen : Dis kin bi pen we de skata ɔlsay na di bɛlɛ, ɔ i kin bi pen we pɔsin kin fil na jɔs wan ples.
• Yu kin fil wan lump we de mek yu fil pen na yu bɛlɛ we de dɔŋ .
• Kɔnstipɛshɔn ɔ bowel obstruction : I kin tan lɛk se yu bɛlɛ dɔn blo ɛn i nɔ kin izi fɔ yu fɔ pas stɔl.
• Nɔs ɛn vɔmit .
• Fiva we nɔ ɛksplen ɛn swet na nɛt .
• We yu nɔ go ebul fɔ imajin fɔ lɔs yu wet .
• Fɔd nɔ kin te .

Impɔtant: If yu kɔntinyu fɔ gɛt wan ɔ mɔ pan dɛn sik ya, i rili impɔtant fɔ go to dɔktɔ fɔ advays. Nɔ wɔri, nɔto ɔl dɛn sayn ya kin kam wit kansa. Dɛn kin kam bak wit ɔda kɔmɔn tin dɛn. Bɔt i bɛtɛ ɔltɛm fɔ mek dɛn chɛk yu.

Wetin na di tin dɛm wae kin mek yu gɛt Pɛritonial Mɛsotelioma?

Di men tin we kin mek pɔsin gɛt mɛsotelioma na we pɔsin de gɛt asbest. Asbest na fayv tin we dɛn kin yuz fɔ bil, fɔ mek plaba, fɔ wok wit ilɛktrik, fɔ mek ruf, fɔ mek sɔm tin dɛn, ɛn fɔ mek motoka dɛn. Bɔrku pipul dɛm wae gɛt mesothelioma gɛt wok wae de mek dɛn gɛt asbestos.

Bɔt pan ɔl we bɔku pipul dɛn we kin gɛt pleura mesothelioma (di kayn we kin afɛkt di lɔng) gɛt histri fɔ gɛt asbest, di link bitwin peritoneal mesothelioma (di kayn we kin afɛkt di layn na di bɛlɛ) ɛn asbest nɔ klia so. Sɔm pipul dɛm wae gɛt peritoneal mesothelioma kin nɔr bin dɔn gɛt histri bɔt aw dɛn bin de gɛt asbestos na dɛn wokples. Dɛn stil de du risach bɔt dis.

Na sɔm ɔda tin dɛn we kin mek pɔsin gɛt `Peritoneal Mesothelioma`:

• Asbestos exposure : We asbestos fayba dɛn kam insay wi envayrɔmɛnt, dɛn kin kam na di briz. We dɛn du dat, dɛn kin go insay wi bɔdi tru wi mɔt ɛn nos, travul go na di layn na di bɛlɛ (peritoneum), ɛn lod de. we dεn dכn lod, dεn de pwεl di mεsotelial sεl dεm, we de mek dεn divayd abnכmal wan. Dis na wetin kin mek kansa tumbu dɛn fɔm. Imajin, mɛsotelioma kin apin sɔm ia afta yu dɔn gɛt asbest, sɔmtɛm i kin te fɔ 40 ia.
• Silica and Erionite Exposure : Dis na kɔmɔn minral dɛm we dɛn kin si na di wɔl. Dɛn dɔn si bak se we pɔsin gɛt dɛn tin ya, i gɛt fɔ du wit ɔl tu di Pleural ɛn Peritoneal Mesothelioma.
• Jin mכtεshכn : Sɔm stכdi dεn sho se if yu de pan asbest εn yu gεt sכm jin mכtεshכn, yu risk fכ gεt pεritoneal mεsotelioma kin bכku. wan pan di mכtεshכn dεm we kכmכn na di chenj na wan jin we dεn kכl BAP1. Dis jin we dɛn kɔl BAP1 na in de mek kansa nɔ gro.
• Radiation exposure : If yu dɔn gɛt redyushɔn tɛrapi fɔ wan kansa na yu bɛlɛ we yu bin dɔn gɛt bifo, dɛn kin tink bak se i kin mek yu gɛt peritoneal mesothelioma. Bɔt dɛn nid fɔ du mɔ risach fɔ ɔndastand gud gud wan di rilayshɔn bitwin redyushɔn ɛn di risk fɔ mek di mɛsotelioma.

Aw yu go no if yu gɛt Pɛritonial Mɛsotelioma?

Fɔ no if pɔsin gɛt Pɛritonial Mɛsotelioma kin tranga, lɛk aw wi bin dɔn tɔk, bikɔs bɔku tɛm i nɔ kin sho di sayn dɛn we i de bigin. We di sayn dɛm kin sho, dɛn kin tan lɛk ɔda kɔmɔn sik dɛm na di bɛlɛ ɔ ɔda kayn kansa. So, bɔku tɛm dɛn kin pul dɛn kɔmɔn tin ya we dɛn de du diagnosis.

Dɛn kin du dɛn tɛst ya fɔ no if yu gɛt di sik:

• CT scan : Yu dɔktɔ kin ɔda fɔ mek dɛn du CT skan fɔ pul ɔda tin dɛn we kin mek yu gɛt sayn dɛn we fiba di peritoneal mesothelioma, lɛk ovarian kansa ɔ adenocarcinoma. Dis kin min fɔ injekt wan sef day (kɔntrast) insay yu blɔd fɔ mek tin dɛn lɛk lumps na yu bɛlɛ de mɔ fɔ si pan di skan.
• MRI skan (Magnetic Resonance Imaging (MRI)) : MRI kin gi di sem lεvεl כf ditel lεk CT skan. Dɛn kin du MRI if yu nɔ ebul fɔ du CT skan wit kɔntrast.
• Blɔd tɛst dɛn: Yu dɔktɔ kin tɛst fɔ sɔm mak dɛn na yu blɔd, lɛk sɔm patikyula prɔtin dɛn, we kin bi sayn fɔ se yu gɛt kansa.
• Peritoneal fluid analysis : Insay dis prosidur, yu dכkta de put nidul insay yu bכdi εn tek sεmpl fכ di fluid fכ chεk fכ sayn dεm fכ mεsothelioma. Bɔt dis tɛst gɛt wan tin we i nɔ ebul fɔ du. I jɔs de gi infɔmeshɔn bɔt di wata we de na yu bɛlɛ, nɔto di tisu we de na yu bɛlɛ. Di stej we di kansa gɛt de dipen pan aw di kansa dɔn skata to di tisu.
• CT-guided core needle biopsy ɔ laparoscopic biopsy : di onli we fɔ kɔnfyus di diagnosis fɔ peritoneal mesothelioma na fɔ gɛt bayɔpsi. Insay dis, yu dɔktɔ kin yuz imej (lɛk skan) fɔ fɛn di rayt say we yu lump de. Dɔn, dɛn kin yuz ɔspitul inschrumɛnt dɛn fɔ tek wan tisu sɛmpul ɛn sɛn am na lɛb fɔ mek dɛn tɛst am.

Wetin na di stej dɛm fɔ Pɛritonial Mɛsotelioma?

Di stej dɛm we di kansa gɛt de sho aw fa di sik dɔn go bifo ɛn aw i dɔn skata. di stej sistεm we dεn kin yus mכst fכ di pεritoneal mεsotelioma na di PCI (Peritoneal Cancer Index).

insay di `PCI` mεtכd, dεn sheb yu bεlε to 13 sεkshכn dεm, εn dεn gi εvri sεkshכn wan skכ frכm 0 to 3.

• 0 min se kansa nɔ de na da eria de.
• 3 min se pat pan am dɔn kɔba wit kansa ɔlsay.

Dɔn di dɔktɔ kin ad di mak dɛn fɔ ɛni wan pan dɛn pat ya ɛn no di stej we di kansa gɛt. Stej 1 na di stej we nɔ de go bifo. Stej 4 na di stej we de go bifo pas ɔl.

• Stej 1: PCI skor frɔm 1 to 10.
• Stej 2: PCI skor frɔm 11 to 20.
• Stej 3: PCI skor frɔm 21 to 30.
• Stej 4: PCI skor 31 to 39.

Wetin na di tritmɛnt fɔ Pɛritonial Mɛsotelioma?

Di tritmɛnt we dɛn kin pik kin dipen pan di stej we yu kansa gɛt, yu ɔl wɛl bɔdi, ɛn sɔm ɔda tin dɛn.

Saytɔridukshɔn ɔpreshɔn ɛn HIPEC tritmɛnt (Saytɔrɔdukshɔn wit HIPEC) .

di tritmεnt we dεn kin yus fכ pεritoneal mεsotelioma na we dεn kכmbayn saytכrεdukshכn כpεrayshכn εn haypatεmik intrapεritכnial kεmothεrapi (HIPEC) .

• Saytoredukshɔn : Dis na ɔpreshɔn we de pul di kansa sɛl dɛn we de insay yu bɛlɛ. Dɔktɔ dɛn go pul ɛni lumps we pɔsin kin si. Dɛn kin pul sɔm pat dɛn bak na di bɛlɛ ɛn di bɛlɛ ɔgan dɛn usay di kansa dɔn skata.
• Hyperthermic intraperitoneal kimotɛrapi (`HIPEC`) .: Dis na spɛshal kayn kemotɛrapi we dɛn kin gi afta dɛn dɔn ɔpreshɔn di saytɔridukshɔn. Dɛn kin wam di kemotɛrapi drɔgs dɛn to say we sef ɛn gi dɛn dairekt insay di bɛlɛ. Dis ɔt de mek di mɛrɛsin dɛn gɛt pawa pas di kemotɛrapi we dɛn kin tek ɔltɛm. HIPEC de kil ɛni smɔl kansa sɛl dɛn we kin dɔn lɛf biɛn we dɛn nɔ bin pul we dɛn bin de du di ɔpreshɔn. HIPEC nɔ gɛt bɛtɛ sayd ɛfɛkt bak pas di kemotɛrapi we dɛn kin gi ɔltɛm.

Saytɔridukshɔn ɔpreshɔn ɛn HIPEC na big, kɔmpleks prɔsidyu we kin tek pas 10 awa. Bɔt risach dɔn sho se dis tritmɛnt we dɛn kin yuz kin ɛp pipul dɛn we gɛt Pɛritonial Mɛsotelioma fɔ liv lɔng.

Kimotɛrapi

If yu nɔ ebul fɔ gɛt saytɔrɔdukshɔn ɔpreshɔn ɛn HIPEC, dɛn kin gi yu sistɛm kimotɛrapi. Sistem kimotɛrapi drɔgs kin travul tru yu blɔd ɛn kil kansa sɛl dɛn ɔlsay na yu bɔdi. Dɛn kin gi difrɛn kayn kemotɛrapi mɛrɛsin dɛn togɛda.

Imyunotɛrapi

di imyun tεrapi dεm we dεn kכl ``immune checkpoint inhibitors`` de εp yu כwn imyun sistεm fכ fכn εn pwεl di kεnsar sεl dεm. Dɛn kin yuse dɛn mɛrɛsin ya fɔ trit ``pleural mesothelioma.`` Yu dɔktɔ kin gi dɛn bak fɔ trit ``peritoneal mesothelioma.``

Targeted therapy

Sɔm pipul dɛm wae gɛt peritoneal mesothelioma kin gɛt chenj na dɛn jɛnɛtiks na dɛn kansa sɛl dɛm. Dɛn kin trit dis wit tritmɛnt dɛm wae dɛn dɔn tɔk bɔt. di tεrapi dεm we dεn de tכk bכt de wok bay we dεn de tכk bכt di jεnεtik chenj dεm we de mek di hεlty sεl dεm bi kεnsar sεl dεm. Dɛn tritmɛnt ya kin de tru yu ɔnkɔlɔjis wae de trit yu, ɔr tru stɔdi dɛm wae dɛn kɔl klinik trial wae de tɛst di sef ɛn ifektiv fɔ nyu tritmɛnt dɛm. I impɔtant fɔ mek dɛn du jɛnɛtik tɛst (jin tɛst) pan di kansa tisu we dɛn tek frɔm yu bayɔpsi fɔ si if yu kansa gɛt dɛn jɛnɛtik chenj ya we dɛn kin tɔch.

Paliativ kia we dɛn kin kia fɔ

Fɔ ɛp yu fɔ kɔntrol di sayn dɛm fɔ kansa ɛn di sayd ɛfɛkt dɛm we di tritmɛnt kin gɛt, yu dɔktɔ kin tɛl yu fɔ kia fɔ yu fɔ mek yu nɔ fil bad. If yu nɔr gɛt wɛl bɔdi fɔ ɔpreshɔn, ɔr if yu kansa dɔn go bifo, palliativ kia kin bi di bɛst opshɔn fɔ yu. Palliative care kin inklud bak tin dεm lεk paracentesis, we de pul wata na di bεlε. Dis kin ɛp fɔ ridyus di diskɔmfɔt ɛn pen we de kam bikɔs ɔf di wata we de bɔku.

Aw yu go ridyus di risk fɔ gɛt dis sik?

di onli we fכ ridyus di risk fכ gεt Pεritoneal Mesothelioma na fכFɔ avɔyd fɔ gɛt asbest. Insay di 1970 dɛm, ɛjɛnshi dɛm lɛk di Envayrɔmɛnt Protɛkshɔn Ajɛns (EPA) na Amɛrika bin put lɔ dɛn bɔt aw fɔ yuz asbest. Bɔt di bildin dɛn we dɛn bil bifo dɛn lɔ dɛn de bigin fɔ wok kin stil gɛt asbest. If dɛn ambɔg di asbest fayv, dɛn kin kɔmɔt na di briz ɛn i kin rili bad.

Fɔ mek yu nɔ gɛt bɔku prɔblɛm, nɔ mek tin dɛn we go mek yu ripɛnt ɔ chenj tin dɛn we go mek yu gɛt asbest. Bifo dat, tek wan spɛshal pɔsin, lɛk pɔsin we sabi fɔ pul asbest, fɔ du dɛn kayn wok dɛn de.

Us kayn op yu kin gɛt we yu de liv wit Pɛritonial Mɛsotelioma?

Pɛritonial mɛsotelioma nɔto sik we pɔsin kin mɛn ɔltogɛda. Bɔt, tritmɛnt kin mek yu liv lɔng ɛn ivin mek yu nɔr gɛt di sik fɔ sɔm tɛm. If yu wok wit wan tim we gɛt ɔnkɔlɔjis we spɛshal fɔ trit mɛsotelioma, dat kin mek yu tritmɛnt go bifo. Fɔ wok wit palliative care professionals kin ɛp bak fɔ mek yu kwaliti layf bɛtɛ as yu de liv wit dis kansa diagnosis.

Us tin dɛn kin afɛkt yu prɔgnosis?

Di prɔgnosis fɔ yu sik kin dipen pan sɔm tin dɛm:

• di kayn sεl dεm : Tri kayn sεl dεm de we kin divεlכp to tכmכro. di tכp we kכmכn pas כl, we dεn kכl εpitelכyd sεl dεm, gεt bεtε prognosis pas di כda tu tכp sεl dεm, sarkomatoid sεl dεm εn biphasic sεl dεm.
• Di stej fɔ yu mɛsotelioma : If dɛn no di sik ɛn trit am fɔs, i go mɔs bi se yu go gɛt bɛtɛ tin fɔ du.
• Yu jɛnɛral : We i kam pan Pɛritonial Mɛsotelioma, dɛn dɔn sho se uman dɛn gɛt bɛtɛ prɔgnosis pas man dɛn.
• Fɔ pul di lumps kɔmplit wan : If yu dɔktɔ ebul fɔ pul ɔl di lumps kɔmplit wan, yu prɔgnosis kin bɛtɛ.
• Trombocytosis : If yu gɛt trombocytosis, yu prɔgnosis kin fayn. Trombocytosis na wan sik wae yu gɛt tumɔs pletlet na yu blɔd. Plɛtlɛt na sɛl dɛn we de ɛp yu blɔd fɔ klɔt.

Aw lɔŋ yu kin liv wit Pɛritonial Mɛsotelioma?

Pipul wae dɛn kin no se gɛt Pɛritonial Mɛsotelioma kin liv fɔ lɛk 6 to 12 mɔnt wae dɛn nɔr gɛt tritmɛnt. Bɔt wit tritmɛnt, di rit we pɔsin kin liv kin bɛtɛ pasmak. Pɛritonial Mɛsotelioma pasɛnt dɛn we dɛn kin du saytɔriduktiv ɔpreshɔn ɛn HIPEC kin liv fɔ tu to siks ia afta dɛn dɔn no se dɛn gɛt di sik. Sɔm pipul dɛn kin liv lɔng pas dat.

Bɔt di prɔgnosis de dipen pan sɔm tin dɛn. Yu dɔktɔ na di bɛst pɔsin fɔ ɔndastand wetin go afɛkt yu prɔgnosis, bay di tritmɛnt we yu go pik.

Wetin na di impɔtant kwɛstyɔn dɛn we yu fɔ aks yu dɔktɔ?

If dɛn no se yu gɛt Pɛritonial Mɛsotelioma, tɔk to yu dɔktɔ bɔt:

• "Udat na di spɛshal dɔktɔ dɛn we go trit mi?"
• "I bɛtɛ fɔ mek a gɛt ɛp frɔm palliativ kia tim?"
• "Us kayn mɛsotelioma a gɛt?"
• "Aw fa mi kansa don spred? (Dat na wetin bi di stej?)"
• "Us tritmɛnt opshɔn dɛn a gɛt?"
• "Ɛni `klinik trayal` (stɔdi dɛn de we de tɛst nyu tritmɛnt) we a kin tek pat pan?"
• "Us rizulyt a kin ɛkspɛkt frɔm di tritmɛnt dɛm we de?"
• "Wetin na di sayd ifekt dɛm fɔ tritmɛnt? Aw dɛn go kɔntrol dɛn?"

Fɔ dɔn, tin dɛn fɔ mɛmba...

Pɛritonial Mɛsotelioma na kansa we nɔ kin bɔku bɔt we kin rili siriɔs. If yu gɛt asbest, dat kin bi wan men tin we kin mek yu gɛt am. If yu gɛt ɛni wan pan di sayn dɛm wae wi dɔn tɔk bɔt, e fayn fɔ go to dɔktɔ kwik kwik wan.

Na nɔmal tin fɔ fil fɔ fred ɛn wɔri we yu kam fɔ no bɔt sik lɛk dis. Bɔt mɛmba se nɔto yu wangren de. Yu gɛt dɔktɔ dɛn, fambul dɛn, ɛn padi dɛn fɔ ɛp yu. Di tin we impɔtant pas ɔl na fɔ gɛt di rayt infɔmeshɔn, tɔk to yu dɔktɔ dɛn opin wan, ɛn gɛt di bɛst tritmɛnt fɔ yu. Tritmɛnt kin rili ɛp fɔ mek yu liv lɔng ɛn fɔ mek yu liv bɛtɛ layf.

` Pɛritonial Mɛsotelioma, kansa, bɛlɛ kansa, asbest, pɛritonial, mɛsotelioma, HIPEC, simptom dɛm, tritmɛnt