Yu tink se yu rɛd blɔd sɛl dɛn bɔku pasmak? Lɛ wi tɔk bɔt Polycythemia Vera (PV)!

Bɔku tɛm yu kin fil taya, sɔntɛnde yu kin fil lɛk se yu de swɛt, ɔ yu kin jɔs yɛri sɔntin we de ring na yu yes? Pan ɔl we dɛn tin ya kin tan lɛk nɔmal tin, sɔntɛnde ɔda rizin kin de biɛn dɛn. So, di sik we wi go tɔk bɔt tide na Polycythemia Vera (PV) , we na wan sik we kin kam bikɔs ɔf di bɔku bɔku rɛd blɔd sɛl dɛn we de na wi bɔdi. Pan ɔl we dis na lɔng nem smɔl, lɛ wi ɔndastand am simpul wan.

Wetin na Polisaytemia Vɛra (PV)? Fɔ tɔk am simpul wan...

Fɔ tɔk am simpul wan, Polycythemia Vera (PV) na wan kכndyushכn we yu bכdi, spεshal wan yu bon mכro (we wi kכl ``Bכn mכro''), de prodyuz mכr rεd bכdi sεl dεm pas aw i fכ mek. Jɔs lɛk aw trafik jam, we bɔku motoka dɛn de na di rod, di blɔd kin ambɔg. Dis kin mek di blɔd tik ɛn travul sloslo. Dis kin mek di blɔd klɔt mɔ ɛn mɔ. Dis kin mek yu gɛt siriɔs prɔblɛm lɛk at atak ɛn strok .

Nɔto dis nɔmɔ, sɔmtɛm di sayn dɛm lɛk di skin we de it, we de ring na di yes (`(Tinnitus)`), bɛlɛ pen, blɔd we de kɔmɔt na yu nos, ɛn we yu nɔ de si fayn kin apin bak.

Polycythemia Vera (PV) na wan sik we nɔ de mɛn we nɔ kin wɛl ɔl. Bɔt nɔ wɔri. If yu gɛt gud mɛrɛsin, yu kin kɔntrol di sik dɛn ɛn ridyus di prɔblɛm dɛn we kin apin to yu. Sɔm pipul dɛn kin kɔl am bak `primary polycythemia`, `polycythemia rubra vera`, `erythema` ɛn `Osler-Vaquez sik`.

Policythemia Vera (PV) na kansa?

Yɛs, fɔ tru, dis na wan kayn kansa. Bɔt i nɔ siriɔs ɔ i nɔ de skata kwik kwik wan lɛk aw wi kin tink we wi yɛri di wɔd kansa. dis na bכdi kεnsar we de pan wan grup we dεn kכl `myeloproliferative neoplasm (MPN) . `MPN` de tכk bכt wan grup fכ sik dεm we de mek difrεn kayn bכdi sεl dεm de כva prodyuz.

di men tin we de mek di Policythemia Vera (PV) de chenj (mכtεshכn) na wan jin na wi bכdi. Dis nɔto sɔntin we dɛn bɔn wi wit, bɔt na sɔntin we kin apin insay wi layf fɔ sɔm rizin we wi nɔ no. Dis sik kin kam kwik kwik wan. Bɔku tɛm dɛn kin no am afta dɛn dɔn ol 60. Dis kansa nɔ kin rili mek pɔsin day dairekt wan. Di men risk kin kɔmɔt frɔm di prɔblɛm dɛn we kin kam we di blɔd kin klɔt. Dɔn bak, if yu nɔ gɛt bɛtɛ blɔd, i kin tɔn to ɔda kayn blɔd kansa.

Udat dɛn dis kayn tin kin afɛkt mɔ?

Polycythemia Vera (PV) na wan sik we nɔ kin bɔku. Insay kɔntri lɛk Amɛrika, i kin apin to lɛk 50 pan ɛvri 100,000 pipul dɛn. E kin bɔrku pan pipul dɛm wae dɔn pas 60 ia.

Aw dis sik kin afɛkt wi bɔdi?

As wi bin dɔn tɔk, Polycythemia Vera (PV) kin mek di bɔdi mek tumɔs rɛd blɔd sɛl dɛn. Dis bɔku bɔku sɛl dɛn kin mek di blɔd kɔmɔt, brus, ɛn blɔd kin klɔt. Bikɔs di blɔd kin tik ɛn travul sloslo, wi bɔdi in tisu ɛn ɔgan dɛn nɔ kin gɛt di ɔksijɛn we dɛn nid.

Dis kin put bɔku wok bak pan wi bɔdi in splin. Wan pan di men wok we di splin de du na fɔ filta blɔd ɛn pul di ol blɔd sɛl dɛn. We di rɛd blɔd sɛl dɛn bɔku, di splin kin wok pasmak bak, ɛn dis kin mek i swel ɛn mek i fil pen. Dɛn kɔl dis `(Splenomegaly)`. As tɛm de go, dis sik kin mek yu gɛt difrɛn sayn dɛm wae nɔr kin fayn fɔ yu. Dɔn bak, PV kin mek ɔda sɛkɔndari kɔndishɔn dɛn.

Wetin na di risk ɛn kɔmplikeshɔn dɛm fɔ Polycythemia Vera (PV)?

Pan ɔl we PV na sik we de go bifo, risk de fɔ mek blɔd klɔt wantɛm wantɛm bikɔs di blɔd sɛl dɛn de bɔku pasmak. As tɛm de go, PV kin mek ɔda sɛkɔndari kɔndishɔn dɛn bak. Na smɔl tɛm nɔmɔ, i kin tɔn to siriɔs kansa.

Blɔd we de klɔt

Dis na di men ɛn mɔs kwik risk fɔ PV. If blɔd klɔt fɔm ɛn travul go na di at ɔ bren, i kin mek pɔsin gɛt at atak ɔ strok . if i travul go na di lכng dεm (Pulmonary Embolism - PE), i kin mek di bכdi prεshכn na di lכng dεm (pulmonary hypertension) εn at fεl. if blɔd klɔt stɔp na wan vein (Venous Thromboembolism - VTE), i kin mek di tisu dɛn day ɔ di venus insufficiency we nɔ de dɔn. If blɔd klɔt stɔp na di men blɔd vesel to di liva (hepatic vein thrombosis), i kin mek blɔd klɔt na di liva (Budd-Chiari syndrome), janda ɛn liva nɔ wok fayn.

Sɛkɔndari kɔndishɔn dɛn

we rεd bכdi sεl dεm de prodyuz pasmak εn brok dכn, di lεvεl fכ `yurik asid` na di bכdi de inkrεs. Dis kin mek wi gɛt bɔku prɔblɛm dɛn:

• Kidni ston: We yurik asid de put insay di kidni.
• Gaut: Na at at sik we de mek pɔsin fil pen we yurik asid bɔku na di jɔyn dɛn.
• Ɔlsa na di bɛlɛ: di ɛkstra rɛd blɔd sɛl dɛn kin mek di bɛlɛ asid bak go ɔp. di ekstra rεd bכdi sεl dεm de mek di bכdi kכl wan kεmikכl we dεn kכl histamin, we in tכn de mek di bεlε prodyuz mכr asid fכ fכt di infεkshכn. Pipul dεm wae gεt PV kin gεt bεlε כlsa (pεptik כlsa sik) lεk fכ tεm mכr.

Fɔ tɔn to Lukimia

Polycythemia Vera na kansa na di bon marrow, bɔt i nɔ kin bi wan sik we kin mek pɔsin in layf de pan denja. If dɛn trit am fayn, dɛn kin ebul fɔ mɛn am fayn fayn wan fɔ lɔng lɔng tɛm. Bɔt fɔ sɔm pipul dɛn, PV kin, pan ɔl we i nɔ kin apin so ɔltɛm, .I kin tɔn to siriɔs blɔd kansa lɛk `Acute Leukemia`.

Stej dɛm fɔ di Policythemia Vera (PV) Disiz

PV sik de go bifo lɛk dis:

• Ali stej (`Early PV`): Insay dis stej, na smɔl ɔ nɔr de simptom.
• PV we de go bifo: As PV de kam tranga, yu kin bigin fɔ gɛt mɔr sik wae nɔr kin fayn, ɔr sɛkɔndari kɔndishɔn kin kam.
• Spent phase: Dɛn kɔl dis “spent phase.” na dis tεm ya, di abnכmal blכd sεl dεm we de mek di sik de mכltipכl we dεn nכ de kכntrכl εn blכk di bon mכro kכmplit wan, we de mek blכd sεl dεm. we dεn abnכmal sεl dεm ya day, ska tisu de fכm insay dεn ples. We bɔku pan di bon mɛro ful-ɔp wit dis ska tisu, i nɔ kin ebul fɔ mek wɛlbɔdi blɔd sɛl dɛn. I fayn fɔ no se dis kin mek dɛn nɔ gɛt bɛtɛ blɔd – we nɔ gɛt wɛlbɔdi rɛd blɔd sɛl. I kin mek bak di risk fɔ mek pɔsin blɔd kɔmɔt.

Ɔda blɔd sik dɛn we kin apin afta PV

We PV kin tranga, i kin mek yu gɛt ɔda sik dɛn na yu blɔd.

• Maylofibrosis (MF): nכ bכku difrεns de bitwin di ``spεnt fεz'' fכ PV εn ``Myelofibrosis (MF)'' , כda kayn bכdi kεnsar. Sɔm dɔktɔ dɛn kin si dɛn di sem tin. ``Myelofibrosis'' na we abnכmal sεl dεm de fכm ska tisu na di bon mכro εn fulכp am. dis abnכmal sεl dεm kin spre ausayd di bon mכro εn go כda pat dεm na di bכdi. ``MF'' na ``mayloproliferative disorder'' bak.Na lεk 10% pan di ``MF'' pasεn dεm de divεlכp ``Acute Myeloid Leukemia.''
• Myelodysplastic Syndrome (MDS): Na sכm tεm, PV kin divεlכp to wan kכndyushכn we dεn kכl Myelodysplastic Syndrome (MDS) . Dis na wan sik we di blɔd sɛl dɛn nɔ kin machɔ fayn, dɛn kin gro fayn, ɛn dɛn kin day kwik kwik wan. di bכdi nכ kin ebul fכ mek hεlty, machכ sεl dεm, we kin mek di nכmba fכ difrεn kayn bכdi sεl dεm dכn dכn. MDS kin tranga pas PV ɔ MF, ɛn i gɛt 30% risk fɔ gɛt Acute Myeloid Leukemia (AML).
• Acute Myeloid Leukemia (AML): Na lɛk 3% pan di pipul dɛm we gɛt Polycythemia Vera kin gɛt Acute Myeloid Leukemia (AML) insay 10 ia afta dɛn dɔn no se dɛn gɛt di sik. AML na wan siriɔs blɔd kansa we kin bigin na di bon mɛro ɛn i kin spre kwik kwik wan to di blɔd ɛn afta dat i kin go na ɔda pat dɛn na di bɔdi. I nid fɔ gɛt tritmɛnt kwik kwik wan, bɔt di chans fɔ mek i nɔ day kin bɔku.

Wetin na di sayn dɛm fɔ Polycythemia Vera (PV)?

Bɔrku tɛm, de sik kin apun kwik kwik wan, ɛn sɔmtɛm nɔr kin gɛt ɛni sayn atɔl. Fɔs, di vayg sayn dɛm wae kin kam pan bɔrku sik dɛm:

• Ed de at.
• Diziz we pɔsin kin gɛt.
• Taya.
• Di ay blɔd prɛshɔn.
• Blɔr vishɔn ɔ dabl vishɔn.
• Fɔ yɛri wan ring na di yes (`(Tinnitus)`).

As tɛm de go, mɔ patikyula sayn dɛn kin apia:

• Swet, mɔ na nɛt.
• I nɔ kin izi fɔ yu fɔ blo, mɔ we yu de ledɔm.
• Skin kin it, mɔ afta yu dɔn was yu wit ɔt wata. (Dis na sɔm patikyula sayn fɔ PV)
• Rɛd, wam, swɛt, ɔ bɔn na di an ɛn fut dɛn.
• Blɔd pasmak ɔ brus.
• Blɔd we de kɔmɔt na di nos ɛn di gɔm.
• Fɔ bi tin fɔ no rizin.

If PV bi siriɔs ɛn go bifo to sɛkɔndari kɔndishɔn, di simptom dɛn we gɛt fɔ du wit am kin apin bak. Fɔ ɛgzampul:

Di sayn dɛm fɔ Splenomegaly:

• Wan pen lɛk sɔntin de stɔp na di ɔp lɛft pat na di bɛlɛ.
• Wan ɛkspiriɛns we de ful-ɔp yu bɛlɛ.
• Ivin afta a dɔn it smɔl, a kin fil ful.

Di simptom dɛm fɔ bɛlɛ ɔlsa (`Pɛptik ɔlsa sik`):

• Pen we kin kam wit bɛlɛ we de at.
• At bɔn.
• Asid riflɔks.

Di sayn dɛn we de sho se pɔsin gɛt Gaut:

• Di jɔyn dɛn we de swel wit pen.
• Di jɔyn dɛn we stif.
• Swel na di big fut.

Di sayn dɛn we de sho se pɔsin gɛt ston na in kidni:

• Pen na di bɛlɛ we de dɔŋ ɔ di flank.
• Pen we yu de pis.
• Nid fɔ pis bɔku tɛm.

Di sayn dɛm fɔ Budd-Chiari syndrome:

• Liva we swel, pen na di ɔp rayt say na di bɛlɛ, ɛn blo.
• Di yay ɛn di skin kin yɔlɔ (jaundice).
• Asayt ɛn Ɛdima.

Di simptom dɛm fɔ Dip Vein Thrombosis (DVT):

• Swel na yu an ɔ yu leg ɛn pen we yu tɔch am.
• Rɛd ɔ wam de na da say de.
• Di we aw di blɔd vesel dɛn we de bulbul kin tan lɛk se na di say we di skin de.

di simptom dεm fכ blɔd kכlכt na di lכng (Pulmonary Embolism - PE):

• I kin pen na yu chɛst wantɛm wantɛm.
• Shot we yu de blo.
• Di at rit de go ɔp.

Di sayn dɛm fɔ Anemia (insay di let stej dɛm fɔ PV sik):

• Diziz (vertigo) we pɔsin kin gɛt.
• Pale skin.
• Taya.

Wetin kin mek pɔsin gɛt Polycythemia Vera (PV)?

Polycythemia Vera (PV) de stat na di sכft, spכnj pat pan wi bon dεm we dεn kכl bon mכro. Na dis say dɛn kin mek nyu blɔd sɛl dɛn. PV de stat wit wan jin mכtεshכn insay wan singl stεm sεl na di bon mכro. mכr dan 90% pan di tεm, dis mכtεshכn de insay wan jin we dεn kכl JAK2.

Dis jin we dɔn chenj de tɛl di stem sɛl fɔ kɔntinyu fɔ bɔn pikin. εvri sεl we dεn prodyuz de kכntinyu fכ rεplik insεf. Afta sɔm tɛm, dɛn nɔmal sɛl dɛn ya kin ful-ɔp di bon mɛro, ɛn dis kin mek di nɔmal sɛl dɛn nɔ gɛt say fɔ de.

כl di kes dεm, dis `JAK2` jin mכtεshכn nכto sכmtin we wi kin inhεrit. Na sɔntin we kin apin we pɔsin de liv in layf, fɔ rizin dɛn we wi nɔ no. Bɔt, na smɔl tɛm nɔmɔ, dɛn dɔn ripɔt se sɔm pipul dɛn na di famili gɛt PV.

Aw dɛn kin no se pɔsin gɛt di sik we dɛn kɔl Polycythemia Vera (PV)?

Di Wol Wɛlbɔdi Ɔganayzeshɔn (WHO) dɔn tɔk bɔt tri men tin dɛn fɔ no if pɔsin gɛt di sik we dɛn kɔl Polycythemia Vera (PV). Dɔktɔ fɔ kɔnfirm ɔl di tri krayteria dɛn.

Krayteria 1: Na blɔd tɛst we de sho se di rɛd blɔd sɛl dɛn bɔku:

Dɛn kin mɛzhɔ di rɛd blɔd sɛl dɛn:

• di hεmoglobin lεvεl (wan protin we de insay di rεd bכdi sεl dεm).
• wan ay hεmatokrit lεvεl (di pasεnshכn fכ di rεd bכdi sεl dεm na di bכdi).
• di ay blɔd volyum (rɛd sɛl mas).

Krayteria 2: Bɔn mɛro bayɔpsi we sho wan pan dɛn tin ya:

• Tumɔs blɔd sɛl dɛn na di bon mɛro, ɔ
• di prεsεns fכ machכ mεgakaryosayt dεm (sεl dεm we de mek bכdi pletlet dεm).

Krayteria 3: Yu kin mit di tɔd krayteria bay we yu sho ɛni wan pan dɛn tu tin ya:

• kכnfכmeshכn fכ di prεsεns fכ di JAK2 jin mכ tεshכn tru mכlikul tεst, כ
• we dεn tεst di bכdi de kכnfכm se di lεvεl fכ `erythropoietin' (wan כmon we de mek di kidni dεm fכ mek rεd bכdi sεl dεm) na di bכdi rili lכw.

"Dɔkta go luk ɔl dɛn tin ya fɔ tɛl yu ɛksaktɔli if yu gɛt Polycythemia Vera ɔ nɔ gɛt am. So if yu gɛt ɛni simptom, i bɛtɛ fɔ go to dɔktɔ ɛn gɛt advays."

Aw dɛn kin trit Polycythemia Vera (PV)?

Insay di fɔs stej dɛm fɔ PV, di tritmɛnt kin rili simpul. Di tritmɛnt dɛn we dɛn kin yuz na:

Plɛbotomi (we dɛn kin pul blɔd) .

Dis na di men ɛn di kɔmɔn tritmɛnt fɔ PV. Dɛn kin du am di sem we aw yu go gi blɔd. Pɔsin we de kia fɔ wɛlbɔdi biznɛs kin put nidul insay wan vein na yu an ɛn pul smɔl blɔd (bɔku tɛm na lɛk wan pint, bɔt di blɔd kin difrɛn difrɛn wan bay aw yu sik). Dis kin mek yu blɔd nɔ bɔku ɛn di ɛkstra blɔd sɛl dɛn nɔ bɔku.

Aspirin we nɔ bɔku

Dis na mɛrɛsin we yu kin bay na di famasi. Bɔku tɛm, dɛn kin gi am fɔ ridyus di risk fɔ mek blɔd klɔt. We dɛn tek am smɔl wan tɛm insay di de, aspirin kin mek di blɔd pletlɛt dɛn nɔ stik togɛda. I kin ɛp bak fɔ ridyus di sayn dɛm lɛk fɔ swel na di an ɛn fut dɛm. Bɔt i kin at smɔl na di bɛlɛ ɛn i kin mek blɔd bɔku. So dis nɔto fayn tin if yu gɛt ɔlsa na yu bɛlɛ.

If yu sik bad bad wan, ɔ if yu gɛt histri bɔt blɔd we dɔn klɔt (thrombosis), dɛn kin put yu na grup we gɛt bɔku prɔblɛm ɛn dɛn kin tɛl yu fɔ du ɔda tritmɛnt. Sɔm pan dɛn tin ya na:

Tritmɛnt fɔ ridyus di it:

We PV kin tranga, dɔktɔ kin gi yu mɛrɛsin lɛk dis fɔ trit di it:

• Antihistamines: Dɛn mɛrɛsin ya na kɔmɔn mɛrɛsin dɛn we dɛn kin gi fɔ alɛji.
• Fɔtotɛrapi: Na tritmɛnt we de miks ɔltra vayolɛt (UVA) layt wit wan kemikal we dɛn kɔl psoralen (wan ɔrganik kɔmpawnd we de mek di skin fil fɔ gɛt layt tɛrapi).
• SSRI (Selective Serotonin Reuptake Inhibitors): Dis na wan kayn mɛrɛsin wae dɛn kin gi pɔrsin fɔ gɛt pwɛl hat. Bɔt we dɛn gi dɛn insay rili smɔl dos, dɛn dɔn si bak se dɛn kin wok fayn fɔ di sik dɛn we de kɔntinyu fɔ de na di bɔdi lɛk fɔ it.

Drug dɛn we de ridyus di rɛd blɔd sɛl dɛn:

Dɛn kin yuz dɛn wan ya ɔ yu kin yuz dɛn togɛda. Ɛgzampul dɛn:

• `Haydroksiyuria`
• `Intɛrfɛrɔn alfa`
• `Rɔksolitinib`
• `Busulfan`

Klinik trial dɛn we dɛn kin du

Dɛn tin ya kin gi pipul dɛn di chans fɔ tray di nyu tritmɛnt dɛn ɛn ɛp fɔ du risach bɔt mɛrɛsin. Sɔm pan di mɛrɛsin dɛn we dɛn de du risach naw na:

• `Pɛgintɛrfɛrɔn alfa-2a`
• `Givinostat` we de na di wɔl
• `Idasanutlin` we de na di wɔl

Fɔ transplant bon mɛrɔ

Sɔntɛnde, dɛn kin se dɛn fɔ transplant bon mɛro. Dɔktɔ go disayd dis bay sɔm tin dɛn lɛk aw yu sik bad ɛn aw yu bɔdi ebul fɔ wɛl.

Sɔpɔtiv kia

If yu PV kɔntinyu fɔ wɔs pan ɔl we dɛn de trit yu, yu dɔktɔ go pe atɛnshɔn fɔ kɔntrol yu sik dɛn. Insay di leta stej dɛm fɔ PV, yu kin gɛt anemia ɛn yu splin kin big. Dɛn kin gi yu tritmɛnt dɛn lɛk:

• Di tin dɛn we dɛn kin yuz fɔ mek pɔsin fil pen.
• Blɔd we dɛn kin gi pɔsin.
• Low-dose redyushɔn tɛrapi to di splin.

Wetin na di layf we pɔsin we gɛt Polycythemia Vera (PV) kin liv?

Stɔdi dɛn we dɛn jɔs dɔn du sho se di avɛrej layf we pɔsin kin liv afta dɛn dɔn no se i gɛt Polycythemia Vera (PV) na lɛk 20 ia. Di avrej ej fɔ day na lɛk 77 ia. Di men tin we kin mek pɔsin day na di kɔmplikeshɔn dɛn we kin kɔmɔt frɔm di blɔd we kin klɔt (lɛk 33%). Di sɛkɔn tin we kin mek pɔsin gɛt kansa (lɛk 15%).

"Nɔ fred wit dɛn statystik ya. Dis na nɔmal valyu. If yu gɛt di rayt tritmɛnt ɛn mek chenj na yu layf, yu kin gɛt wɛlbɔdi fɔ lɔng tɛm."

Aw a go tek kia ɔf misɛf ɛn kɔntrol mi sik dɛn?

If yu de liv wit Polycythemia Vera (PV), i impɔtant fɔ de kɔntakt yu dɔktɔ ɔltɛm. Dis go ɛp yu dɔktɔ fɔ wach aw yu sik de go bifo. Yu kin tɛl yu dɔktɔ bak aw yu de du tritmɛnt ɛn if yu de gɛt ɛni sayd ɛfɛkt. Yu kin liv fɔ lɔng tɛm ɛn nɔr gɛt siriɔs sik.

Apat frɔm di tɛst ɛn tritmɛnt we dɛn kin du ɔltɛm, yu dɔktɔ go tɔk bak bɔt sɔm simpul chenj dɛn na yu layf we go ɛp fɔ mek yu nɔ gɛt blɔd klot ɛn ɔda prɔblɛm dɛn. Fɔ ɛgzampul:

• Ɛksasayz. Ivin smɔl ɛksesaiz kin ɛp fɔ mek di blɔd go fayn fayn wan.
• Nɔ smok. Smok kin mek yu blɔd vesel dɛn smɔl.
• Avɔyd say dɛn we ɔksijɛn nɔ bɔku. If yu de ay ay, dat kin mek di ɔksijɛn we de na di blɔd nɔ bɔku.
• Kɔntrol yu blɔd prɛshɔn. If yu kɔntinyu fɔ gɛt wɛlbɔdi wet, dat go ɛp fɔ du dis.

Pan ɔl we Polycythemia Vera (PV) na wan kayn kansa, bɔku pipul dɛn kin liv fayn fɔ bɔku bɔku ia afta dɛn dɔn no se dɛn gɛt dis sik. Dis kansa kin apin bikɔs dɛn kin mek di sɛl dɛn we dɛn nɔ ebul fɔ kɔntrol. Bɔt i kin tek lɔng tɛm fɔ mek di rɛd blɔd sɛl dɛn we yu nɔ ebul fɔ kɔntrol bigin fɔ afɛkt yu. Ivin if yu du dat, yu kin ebul fɔ kɔntrol di sik fɔ lɔng tɛm bay we yu pul sɔm pan yu blɔd we pasmak.

Di big trɛt frɔm Polycythemia Vera (PV) nɔto di kansa insɛf, bɔt na di risk fɔ mek blɔd klɔt. If yu de liv wit PV, mek shɔ se yu de si yu dɔktɔ ɔltɛm. Ɛn nɔ fɔgɛt fɔ tek kia ɔf yusɛf wit di "smɔl tin dɛm" - dat na, wɛl bɔdi layf abit dɛm. Dɛn tin ya kin ɛp fɔ mek yu kɔntinyu fɔ gɛt di jenɛral wɛlbɔdi na yu at ɛn blɔd sistɛm, we kin impɔtant pas ɛni mɛrɛsin fɔ Polycythemia Vera.

Wetin na di mɛsej we wi want fɔ kɛr go na os frɔm dis stori?

Okay, so wi don tok plenti boht Polycythemia Vera (PV). Na sɔm pan di impɔtant tin dɛn we yu fɔ mɛmba:

• PV na blɔd sik we di bɔdi de mek tumɔs rɛd blɔd sɛl ɛn gro nɔmal wan. i de pan wan grup fכ kεnsar dεm we dεn kכl `mayloproliferative neoplasm (MPN)`.
• Di men risk kin kam wae blɔd tik ɛn blɔd kin klɔt, we kin mek yu gɛt siriɔs sik lɛk at atak ɛn strok.
• Di sayn dɛm kin bi wae yu skin kin it (espɛshali afta yu dɔn was), yu kin fil lɛk yu taya, yu ed kin at, ɛn yu kin gɛt diziz.
• Pan ɔl we dɛn nɔ go ebul fɔ mɛn am ɔl, dɛn kin ebul fɔ mɛn am fayn if dɛn trit am fayn, chenj in layf, ɛn tek mɛrɛsin. Plɛbotomi (blɔd) ɛn smɔl doz aspirin na di praymar tritmɛnt.
• di `JAK2` jin mכtayshכn na di kכz fכ dis bכku tεm.
• If yu gɛt ɛni wan pan dɛn sik ya, mek shɔ se yu go to dɔktɔ fɔ advays. If yu no am kwik, dat kin mek yu gɛt mɔ chans fɔ avɔyd prɔblɛm dɛn ɛn liv fayn layf.

Nɔ fred, bɔt nɔ tek am layt sɛf. Tek kia ɔf yu wɛlbɔdi. Tɔk to yu dɔktɔ ɔltɛm, gɛt di tɛst ɛn tritmɛnt dɛn we yu nid di rayt tɛm. Dɔn yu kin gɛt wɛlbɔdi ivin wit dis sik!

` Polycythemia Vera, Rεd Blɔd Sεl, Blɔd Klɔt, MPN, JAK2, Flebotomy, Kansa