Yu dɔn ɛva tink bɔt aw i impɔtant fɔ mek blɔd klɔt na wi bɔdi? Na bikɔs ɔf dis prɔses we blɔd kin stɔp we smɔl injuri de. Bɔt, wetin fɔ du if blɔd klot insay di bɔdi fɔ natin? Dat kin denja smɔl. Tide wi go tɔk bɔt dis kayn kɔndishɔn. dat na di Protein S dεfisiεns, כ `(Protein S Dεfisiεns)`.
Fɔ tɔk am simpul wan, wetin na Protein S dɛfisiɛns?
Tink bɔt di we aw blɔd de klɔt na wi bɔdi lɛk trafik polis ɔfisa we de kɔntrol trafik jam. Sɔmbɔdi nid fɔ de fɔ kip ɔltin in chɛk. Semweso, wan pan di imכtant protin dεm we de kכntro di bכdi we de kכlכt na wi b כdi na Protein S.
naw, we di Protein S dεfichεns min se wi gεt sכm di wan we dεn kכl "polis כfisa" כ Protein S na wi bכdi pas aw wi nid. Wetin kin apin da tɛm de? Bikɔs nɔbɔdi nɔ de fɔ kɔntrol di we aw di blɔd de klɔt, i kin wok pasmak ɛn blɔd kin bigin fɔ klɔt we i nɔ nid.
Blɔd klɔt we kin mek dis kayn we kin fɔm bɔku tɛm na di dip vein dɛn na di leg dɛn. Wi kin kɔl dis dip vein trombosis (DVT) . Sɔntɛnde dis blɔd klɔt kin brok frɔm de ɛn travul wit di blɔd to di lɔng dɛn ɛn stɔp. Dis na tin we de mek pɔsin denja pas ɔl. Wi kin kɔl am pulmonary embolism (PE) . Na smɔl tɛm nɔmɔ dɛn blɔd ya kin mek bak na di vein dɛn na di bren ɔ di bɛlɛ.
Bɔt wan impɔtant tin de we yu fɔ rili mɛmba na ya. Dat min se nɔto ɔlman we gɛt dis Protein S dɛfisiɛns kin gɛt blɔd klɔt. Bɔrku pipul dɛn kin liv nɔrmal layf ɛn nɔr gɛt ɛni prɔblɛm.
Aw dis sik kin kɔmɔn? Ɛn ustɛm di prɔblɛm kin pas ɔl?
di prכtin S dεfichεshכn na rili wan kכndyushכn we nכ kin apin. Bɔrku tɛm, na hereditary, min se na jenɛtik. Bɔt sɔm tin dɛn we de na do kin mek am bak.
If yu gɛt dis sik, sɔm tin dɛn kin de we yu kin gɛt mɔ risk fɔ mek yu blɔd klɔt. Lɛ wi tek tɛm luk wetin na dɛn tin dɛn de.
| Di chans fɔ mek di risk bɔku | Wan simpul ɛksplen |
|---|---|
| We uman gɛt bɛlɛ | we uman bεlε, di bכdi in כmon dεm we de chenj εn di chenj dεm we di bכdi de chenj de mek di bכdi kin kכlכt. |
| We pɔsin de ol | Di risk kin go ɔp wit di ej as di bɔdi in wok de dכn ɛn ɔda mεdikal kכndyushכn dεm kin apin. |
| Sɔm mɛrɛsin dɛn | If yu tek bɔn kɔntrol pils ɔ ɔda ɔmon tritmɛnt, mɔ, dat kin mek yu gɛt mɔ prɔblɛm. |
| Dɛn de du ɔpreshɔn pan am | Afta dɛn dɔn du big ɔpreshɔn, yu kin de na bed fɔ sɔm tɛm, we kin mek yu blɔd nɔ go fayn ɛn blɔd kin klɔt. |
| Shɔk | Afta big aksidɛnt, di bɔdi kin lɛk fɔ klɔt kin bɔku as dis ansa. |
| Fɔ de na di sem pozishɔn fɔ lɔng tɛm | Fɔ ɛgzampul, tin dɛn lɛk fɔ flay fɔ lɔng tɛm ɔ fɔ sik we yu de na bed kin mek blɔd nɔ go na di leg ɛn mek yu gɛt DVT. |
Wetin na di sayn dɛm fɔ dis sik?
Bɔrku tɛm, pɔrsin wae nɔr gɛt Protein S nɔr go gɛt ɛni sayn te blɔd klɔt. If blɔd klɔt, di sayn dɛm go difrɛn difrɛn wan bay usay i fɔm.
- If yu gɛt blɔd klɔt (DVT) na yu leg:
- Wan leg de swel, mɔ di say we di groin de swel.
- Fɔ fil pen ɔ stiff na di leg.
- Rɛd ɔ fil wam na di skin na di leg.
- If yu gɛt blɔd klɔt (PE) na yu lɔng (dis na imejensi):
- I nɔ kin izi fɔ yu fɔ blo wantɛm wantɛm.
- Chɛst pen, mɔ we yu de tek dip briz.
- Fɔ brith kwik kwik wan ɛn fɔ mek yu at rit fɔ natin.
- Diziz ɔr nɔr kin no natin.
- Blɔd we de kɔmɔt na di mכkus.
- We uman gɛt bɛlɛ: I kin mek di bɛlɛ ɔ ɔda prɔblɛm dɛn apin.
- Na yכŋ pikin dεm (insay di wan dεm we kin tranga pas כl): Kכndyushכn dεm we lεk strכk kin apin.
Wetin mek dis Protein S dɛfisiɛns kin apin?
Tu men rizin dɛn de fɔ dis. Wan na inherited (inherited) ɛn di ɔda wan na acquired (acquired) .
1. Di tin dɛn we kin mek pɔsin gɛt frɔm in mama ɛn papa
Dis na di wan we bɔku pipul dɛn kin du. di prodakshכn fכ Protein S na wi bכdi na wan jin we dεn kכl PROS1 de kכntro am. if mכtεshכn כ chenj de na dis jin, di prodakshכn fכ Protein S de pwεl.
- If yu gɛt dis mutated jin frɔm wan mama ɔ papa nɔmɔ , yu go gɛt smɔl Protein S deficiency.
- If yu gɛt dis jin frɔm yu mama ɛn papa ɔl tu , yu go gɛt wan rili siriɔs we fɔ di dɛfisiɛns. Dis nɔ kin apin so ɔltɛm.
2. Di tin dɛn we kin mek pɔsin kɔmɔt na do
Sɔm mεdikal kɔndishɔn ɔr tin kin mek bak di Protein S nɔr de na di bɔdi. Dis kin kɔmɔn pas we pɔsin kin gɛt frɔm in mama ɛn papa.
| Sɔm tin dɛn we kin mek pɔsin kɔmɔt na do |
|---|
| Liva sik |
| Kidni sik ɛn nɛfrɔtik sindrom |
| Kimotɛrapi fɔ kansa |
| Sɔm infɛkshɔn dɛn |
| Vitamin K we nɔ de |
| Yuz pil fɔ kɔntrol uman we gɛt bɛlɛ ɛn we yu de bɔn pikin |
Aw yu go fɛn dis, Dɔktɔ?
Yu dɔktɔ kin sɔprayz bɔt dis, mɔ pan tin dɛn lɛk dis:
- If pɔsin na yu famili gɛt histri fɔ gɛt blɔd we kin klot bɔku tɛm (Venous Thromboembolism).
- If yu gɛt blɔd we de klɔt bɔku tɛm .
- If yu dɔn gɛt blɔd we dɔn klot bifo yu ol 50 ia, we dɛn nɔ fɛn ɛni patikyula rizin .
- If blɔd klɔt dɔn fɔm na say dɛn we nɔ kɔmɔn usay blɔd klɔt nɔ kin fɔm nɔmal wan (lɛk di bren, intestinal, liva) .
If dis kayn saspekshɔn kam, di dɔktɔ go du dɛn tin ya fɔ kɔnfirm di sik:
1. Blɔd tɛst: Dɛn go tɛst yu blɔd fɔ si if yu gɛt Protein S lɛvɛl ɛn ɔda tin dɛn we gɛt fɔ du wit blɔd we de klɔt.
2. Fɔ chɛk yu bɔdi: Dɛn go du kɔmplit bɔdi ɛgzamin fɔ chɛk fɔ ɔda prɔblɛm dɛn.
3. Yu mɛdikal istri: Wi go aks yu bɔt yu mɛdikal kɔndishɔn ɛn yu famili.
Aw dɛn kin trit am?
Di we aw dɛn de trit yu dipen pan if yu gɛt blɔd we de klɔt ɔ yu nɔ gɛt.
Di impɔtant tin na dat, ivin if blɔd tɛst sho se yu nɔ gɛt Protein S, if yu nɔ ɛva gɛt blɔd klot, i go mɔs bi se yu nɔ go nid fɔ kɔntinyu fɔ tek mɛrɛsin.
Bɔt if yu dɔn ɔlrɛdi gɛt blɔd we de klɔt (DVT ɔ PE), yu dɔktɔ go bigin yu fɔ tek mɛrɛsin we de mek yu blɔd blɔd . Dɛn tin ya kin wok bay we dɛn kin mek nyu blɔd klɔt nɔ fɔm ɛn bay we dɛn kin mek di blɔd we dɔn de nɔ big. Di kayn mɛrɛsin dɛn we dɛn kin yuz mɔ na:
- Heparin we dɛn kin yuz
- Warfarin we dɛn kɔl Warfarin
- Rivaroxaban we dɛn kɔl Rivaroxaban
- Apixaban we dɛn kɔl Apixaban
- Dabigatran we dɛn kɔl Dabigatran
Na sɔntin we yu fɔ no: If yu dɔktɔ disayd fɔ gi yu wan mɛrɛsin we dɛn kɔl ``Warfarin,'' i go nid fɔ gi yu wan mɛrɛsin we dɛn kɔl ``Heparin'' (bɔku tɛm as injɛkshɔn) sɔm dez bifo. If yu nɔ du dat, sɔntɛnde yu kin gɛt wan prɔblɛm we dɛn kɔl blɔd klot na di skin ɛn di sɔft tisu dɛn. Bɔt dis prɔblɛm nɔ kin apin wit ɔda nyu mɛrɛsin dɛn.
Yu tritmɛnt kin las frɔm sɔm mɔnt to yu layf, i kin dipen pan ustɛm yu blɔd klɔt ɛn ɔda tin dɛn we kin mek yu gɛt dis sik.
Wetin yu kin du fɔ pipul dɛm wae nɔr gɛt blɔd klɔt, bɔt dɛn gɛt deficiency?
Di dɔktɔ in gol fɔ pipul dɛn lɛk dis na fɔ ɛp fɔ mek blɔd nɔ klɔt.
- Dɛn kin advays yu fɔ nɔ tek mɛrɛsin dɛn we de mek blɔd klot mɔ ɛn mɔ, lɛk pils we de mek yu nɔ bɔn pikin.
- If dɛn de du ɔpreshɔn pan yu, yu gɛt bɛlɛ, ɔ yu nɔ de na bed fɔ sɔm tɛm bikɔs ɔf aksidɛnt , dɛn kin se yu fɔ yuz blɔd tin fɔ sɔm tɛm fɔ da tɛm de nɔmɔ.
Aw a fɔ kia fɔ misɛf?
- If yu de tek Warfarin: Yu go nid fɔ mek dɛn chɛk yu INR ɔltɛm .Yu go nid fɔ du blɔd tɛst. Dis go chɛk if di doz fɔ `(Warfarin)` we dɛn de gi yu kɔrɛkt. Bikɔs dɛn kin nid fɔ chenj di doz fɔ dis mɛrɛsin wan wan tɛm.
- If yu de tek mɛrɛsin we de mek yu blɔd tan: Tek tɛm fɔ mek yu blɔd kɔmɔt. Tek tɛm we yu de yuz tin dɛn we shap lɛk naif. I bɛtɛ fɔ yuz tut brɔsh we saf ɛn ilɛktrik reza.
- Yu fɔ no di sayn dɛm fɔ DVT ɛn PE: Yu fɔ ebul fɔ no di sayn dɛm lɛk fɔ swel yu leg, fɔ pen na yu chɛst, ɛn fɔ blo shɔt if dɛn apin.
Ustɛm a fɔ si di dɔktɔ ɛn go na di ETU?
### Kɔl yu dɔktɔ wantɛm wantɛm pan dɛn kayn tin ya:
- If yu fɔdɔm ɔ gɛt ɔda aksidɛnt we yu de tek mɛrɛsin we de mek yu blɔd tan.
- If ɛni blɔd we nɔ kɔmɔn de (e.g. blɔd we de kɔmɔt na di nos, blɔd na yu urine ɔ stɔl).
- If yu sɔspɛkt se yu gɛt DVT (blɔd we de klɔt na yu leg) .
### If yu gɛt dɛn sik ya, go to di Imejɛnsi Dipatmɛnt (ETU) wantɛm wantɛm:
- If yu de tek blɔd tina ɛn yu de vɔmit blɔd ɔ kɔf blɔd .
- If yu nak yu ed ɔ yu gɛt bad bad ed pen wantɛm wantɛm .
- If blɔd de we dɛn nɔ go ebul fɔ stɔp .
- If yu tink se yu gɛt sayn dɛm fɔ PE (blɔd we de klɔt na di lɔng) (we yu de blo wantɛm wantɛm, yu chɛst de pen, yu at de bit kwik kwik wan, yu de tɔn diziz).
Mɛsej we dɛn kin kɛr go na os
- di protin S we de dכn na wan kכndyushכn we de mek di bכdi fכ kכlכt bכku. Bɔku tɛm, dis na tin we pɔsin kin gɛt frɔm dɛn mama ɛn papa.
- Nɔto ɔlman we gɛt dis prɔblɛm kin gɛt blɔd klɔt. Bɔku pipul dɛn nɔ kin gɛt ɛni prɔblɛm.
- Ɔltɛm yu fɔ no bɔt di sayn dɛm lɛk fɔ swel yu leg, pen (DVT) ɛn fɔ blo shɔt wan wantɛm wantɛm ɛn pen na yu chɛst (PE).
- If dɛn dɔn gi yu mɛrɛsin fɔ mek yu blɔd tan, tek am jɔs lɛk aw yu dɔktɔ tɛl yu, di rayt doz, di rayt tɛm. Nɔ ɛva stɔp fɔ tek di mɛrɛsin.
- If ɛni sayn we de mek yu sɔfa wantɛm wantɛm, nɔ fred fɔ go to dɔktɔ wantɛm wantɛm ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU).
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