Lɛ wi lan bɔt Rediofamasitikal insay wan simpul we. Dis go rili impɔtant fɔ yu!

Yu go mɔs fred smɔl we yu yɛri di wɔd "radiopharmaceuticals," nɔto so? Di wɔd "radioactive" kin mek yu mɛmba sɔntin we denja wantɛm wantɛm, bɔt we yu yuz am fayn fayn wan na mɛrɛsin, dɛn kin ɛp yu bad bad wan. So tide, lɛ wi tɔk bɔt wetin dɛn bi, aw dɛn de wok, ɛn aw dɛn sef fɔ yu.

Wetin na dɛn redio famasitik ya? Lɛ wi ɔndastand am simpul wan!

Fɔ tɔk am simpul wan, dɛn `(Radiopharmaceuticals)` ya na spɛshal kayn mɛrɛsin bak . Bɔt dɛn gɛt smɔl redioaktiv ɛlimɛnt, dat min se dɛn gɛt redioaktiv. Nɔ wɔri, dis na kɔntrol, sef redioaktiviti. Wi dɔktɔ dɛn, dat na, dɔktɔ dɛn ɛn di wan dɛn we de kia fɔ wɛlbɔdi biznɛs we gɛt fɔ du wit am, kin yuz dɛn mɛrɛsin dɛn ya fɔ tɛst dɛn pikchɔ dɛn na nyuklia mɛrɛsin ɛn fɔ trit sɔm sik dɛn, mɔ di tumbu dɛn we gɛt kansa .

Tink bɔt am, we dɛn want fɔ si if sɔntin nɔ rayt insay yu bɔdi, sɔntɛnde dɔktɔ dɛn kin gi yu smɔl mɛrɛsin fɔ drink ɔ dɛn kin gi yu injɛkshɔn bifo dɛn skan yu? Dis na sɔntin we tan lɛk dat. Na pipul dɛn we gɛt spɛshal trenin we dɛn kɔl nyuklia fama de mek ɛn gi dɛn spɛshal mɛrɛsin ya . Dɔn , raydiɔlɔjis ɛn raydiɔlɔjik tɛknɔlɔjis (RT) kin yuz dɛn fɔ du diagnostik imej tɛst. Sɔntɛnde, di wan dɛn we de stɔdi bɔt rɛdyushɔn ɔnkɔlɔji kin gi dɛn mɛrɛsin ya bak as tritmɛnt.

Wetin dɛn kin yuz dɛn redio famasitik ya fɔ?

Dɛn kin yuz dɛn mɛrɛsin ya mɔ pan tu pat. Lɛ wi si wetin dɛn bi.

1. Diagnostik RedioFamasiutik

Bɔku tɛm dɛn kin yuz redio famasitik fɔ du nyuklia mɛrɛsin imej tɛst . Wi kin kɔl dɛn tin ya "diagnostic radiopharmaceuticals." Insay Amɛrika nɔmɔ, dɛn se dɛn kin du bɔku bɔku pan dɛn nyuklia mɛrɛsin ya ɛvri ia. So yu kin imajin aw dɛn de yuz dɛn bɔku bɔku wan.

Dɛn tɛst ya kin chɛk if di ɔgan ɛn tisu dɛn we de insay yu bɔdi de wok fayn . Dɛn kin du dis lɛk dis:

Dɛn kin gi yu smɔl smɔl pan dis redioaktiv mɛrɛsin fɔ drink, inhal, ɔ injɛkt. Sɔntɛnde dɛn kin kɔl dɛn tin ya redio traysa . Di amount of redioaktiv mɛrɛsin we dɛn gi yu nɔ go ambɔg yu. Na smɔl tin we rili smɔl. Dis mɛrɛsin kin go na di say we prɔblɛm de na yu bɔdi ɛn i kin gɛda. Dɔn, wan kamɛra we rili sɛnsitiv, lɛk gama kamɛra, kin no di raytin we de na yu bɔdi ɛn mek pikchɔ dɛn we di dɔktɔ kin si.

Imajin, dis mɛrɛsin tan lɛk ditektiv we de go insay di bɔdi, de fɛn di say dɛn we di prɔblɛm de ɛn sho wi se, "Na dis say di prɔblɛm de."

Na sɔm ɛgzampul dɛn bɔt aw dɛn kin yuz redio famasitik fɔ no if pɔsin gɛt sik:

• Fluorine-18: Dis na rediotracer we dɛn kin yuz bɔku tɛm fɔ du PET skan (Positron Emission Tomography scans).
• Technetium 99m: Dis na di redioaktiv ɛlimɛnt we dɛn kin yuz mɔ na nyuklia mɛrɛsin. Dɛn kin yuz am fɔ chɛk di bon dɛn, di we aw di liva de wok, ɛn di we aw di kidni de wok.
• Xenon-133: Dis na redioaktiv drɔg we yu de inhal. dεn kin gi am fכ chεk di lכng fכnshכn (pulmonary function testing).
• Rubidium-82: Dis na drɔg we dɛn kin gi yu insay yu bɛlɛ (IV). dεn kin yus am fכ luk di kכndishכn fכ di at mכsul (myocardial imaging).

2. Tɛrapi RedioFamasiutik dɛn

Naw lɛ wi tɔk bɔt aw dɛn kin yuz dɛn mɛrɛsin ya fɔ mɛn. Dɛn tin ya difrɛn smɔl frɔm di wan dɛn we dɛn kin yuz fɔ no if pɔsin gɛt di sik. Di redio famasitik dɛn we dɛn kin yuz fɔ mɛn di sik kin mek dɛn gɛt raytin we rili pawaful ɛn we kin kil di sɛl dɛn . Dɛn kin du dis fɔ kil di sɛl dɛn we nɔ gɛt wɛlbɔdi, mɔ di kansa sɛl dɛn .

Dɛn drɔgs ya tan lɛk "bounty hunters." Dat min se dɛn kin fɛn kansa sɛl dɛn ɛn gi redyushɔn tɛrapi dairekt to dɛn sɛl dɛn de . Dis difrɛn frɔm ɛksternal bim redyushɔn tɛrapi , we de yuz mashin fɔ sɛn bim dɛn we gɛt raytin frɔm ɔdasay na yu bɔdi. Bɔt dɛn tritmɛnt redio famasitik ya de wok dairekt bay we dɛn de tɔch di pɔsin we dɛn want fɔ du.

Dis fild, di yus fɔ redioaktiv drɔgs fɔ tritmɛnt, na nyu tin. Risach pipul dɛn stil de fɛn nyu we dɛn fɔ yuz dɛn. Dɛn biliv se di tritmɛnt we dɛn kin yuz fɔ mɛn pipul dɛn we gɛt redio famasitik go rili impɔtant fɔ mɛn kansa tumara bambay.

Wetin na redio famasitik dɛm we dɛn kin yuz fɔ mɛn kansa?

Bɔku kayn ``Radiopharmaceuticals`` de we dɔktɔ dɛn kin yuz fɔ trit kansa. Fɔ ɛgzampul:

• PLUVICTO® (lutetium Lu 177 vipivotide tetraxetan): Dis na wan mɛrɛsin we di US Food and Drug Administration (FDA) dɔn gri fɔ. dεn de yuz am fכ trit prכstat kεnsar (PSMA-positiv mεtastas kεstrashכn-rεsistant prכstat kεnsar - PSMA-positiv mCRPC).
• LutatheraTM `(LutatheraTM - Lutetium Lu 177 dotatate)`: di wan dɛn we de wok wit di bɔdi.Dis na mɛrɛsin bak we FDA dɔn gri fɔ. dεn kin yus am fכ trit sכm nyuroεndokrin tכmכro dεm (somatostatin rεsεptכr-positiv gastroenteropancreatic nyuroεndokrin tכmכro dεm) we de apin na di bεlε, intestinal, εn pankrias.
• Ayodin-131: Dis na di men we aw dɛn kin yuz redioaktiv ayodin tɛrapi. I kin trit sɔm tayroyd kansa ɛn sɔm kes dɛm fɔ Graves in sik, we dɛn kin kɔl bak haypa tayroyd.
• Radium-223: Dis kin rili wok fכ trit bon tכmכro dεm we kin apin we prכstat kεnsar spre (mεtastas) to di bon dεm. Di US FDA dɔn gri fɔ Radium-223 dichloride (XofigoTM) fɔ dis.

Apat frɔm dat, sɔm ɔda kayn redio famasitik tritmɛnt dɛn de na klinik trial naw fɔ ɔda kayn kansa.

Wetin na di redio famasitik dɛm we dɛn kin yuz mɔ?

As wi bin dɔn tɔk, Technetium-99m na redio famasitik we dɔktɔ dɛn kin yuz mɔ. Dɛn kin yuz am mɔ fɔ tɛst fɔ no if pɔsin gɛt di sik. I de ɛp fɔ "si" dɛn tin ya:

• Pulmonary perfusion (blɔd flɔ) na yu lɔng.
• Blɔd de flɔ na yu vaskul sistɛm (Vascular perfusion).
• Bɔn dɛn.
• Tisu na di mayokardia.
• Gland dɛn we de mek pɔsin kray.
• Tayrɔyd gland we dɛn kɔl.

Sɔm ɔda redio famasitik dɛn we dɛn kin yuz na:

• 18F Fluorodeoxyglucose `(18F Fluorodeoxyglucose - FDG)`
• Galiɔm-68 DƆTƐT
• Galium-68 PSMA `(Galium-68 PSMA)`
• 18F PSMA `(18F PSMA)`
• Ayodin 123 `(Ayodin 123)`

So yu tink se dɛn redio famasitik ya rili sef?

Dis na kwɛstyɔn we bɔku pipul dɛn gɛt. We dɛn yuz am ɛn manej am fayn, redio famasitik nɔ sef. Yu raydiɔlɔjis ɛn/ɔ redyushɔn ɔnkɔlɔjis go wok wit nyuklia fama fɔ mek shɔ se di amount ɔf redio famasitik we dɛn gi yu kɔrɛkt ɛn sef . So natin nɔ de fɔ wɔri bɔt.

Lɛk ɔl di mɛrɛsin dɛn, redyushɔn tɛrapi kin mek sɔm bad bad tin dɛn apin . Bɔt di bɛnifit dɛn we di mɛrɛsin kin gi kin bɔku pas di prɔblɛm dɛn we i kin gɛt. Yu dɔktɔ go ɛksplen to yu dɛn kayn bad bad tin ya we kin apin bifo yu bigin fɔ trit yu.

Pan ɔl we dɛn dɔn de yuz redio famasitik fɔ lɔng lɔng tɛm fɔ mek nyuklia mɛrɛsin imej, na jɔs naw dɛn bigin fɔ yuz dɛn fɔ mɛn kansa. Risach pipul dɛn stil de stɔdi aw dɛn redioaktiv drɔgs ya de atak ɛn kil di kansa sɛl dɛn. If yu want fɔ no bɔt klinik trial fɔ redio famasitik fɔ mɛn kansa, tɔk to yu dɔktɔ. Dɛn kin gladi fɔ ɛp yu.

Fɔ dɔn, di tin dɛn we impɔtant pas ɔl we yu fɔ mɛmba

Okay, so, frɔm wetin wi dɔn tɔk bɔt, na dɛn men tin ya yu nid fɔ mɛmba:

• Redio famasitik na spɛshal kayn mɛrɛsin we dɔn kɔntrol redioaktiviti .
• Dɛn kin yuz dɛn tin ya mɔ fɔ tɛst di imej we pɔsin kin no (e.g. PET skan, bon skan) ɛn fɔ trit sɔm sik dɛn, mɔ di kansa .
• insay diagnostik, dεn ya de wok lεk ``Radiotracers'', we de "point out" di εria dεm na di bכdi usay prכblεm de.
• Insay tritmɛnt, dɛn tin ya kin ɛp fɔ tɔch ɛn pwɛl di kansa sɛl dɛn .
• Dɛn mɛrɛsin ya nɔ bad we dɛn gi dɛn ɔnda di rayt dɔktɔ we de kia fɔ dɛn . Jɔs lɛk ɔl di mɛrɛsin dɛn, smɔl smɔl sayd ɛfɛkt dɛn kin de, bɔt bɔku tɛm di bɛnifit dɛn kin pas dɛn.
• Dis fild, mɔ pan kansa tritmɛnt, stil de evolv , ɛn wi kin op fɔ gɛt bɔku ɔda tin dɛn tumara bambay.

So, di nɛks tɛm we yu yɛri bɔt ``(Radiopharmaceutical)'', yu dɔn ɔndastand mɔ bɔt wetin i bi ɛn wetin dɛn de yuz am fɔ, nɔto so? If yu gɛt ɛni ɔda kwɛstyɔn, nɔ shem fɔ aks yu dɔktɔ ɔltɛm.

` Rediofamasiutik, Nyuklia Mɛdisin, Kansa Tritmɛnt, Skan, Redio Tɛrapi, Diagnosis