Yu dɔktɔ dɔn gi Ribociclib fɔ brɔst kansa fɔ yu ɔ pɔsin na yu famili? Na nɔmal tin fɔ gɛt bɔku kwɛstyɔn bɔt dis mɛrɛsin, aw i de wok, ɛn di sayd ɛfɛkt dɛm we i gɛt. Nɔ wɔri. Insay dis atikul, wi go ɛksplen ɔltin simpul wan, jɔs lɛk aw yu de tɔk to yu padi.
Wetin rili na dis drɔg we dɛn kɔl Ribociclib?
Fɔ tɔk am simpul wan, Ribociclib na kansa drɔg we de pan di kategori we dɛn de tɔk bɔt fɔ mɛn pipul dɛn. I de wok bay we i de blok di akshɔn fɔ sɔm prɔtin dɛn we de insay di kansa sɛl dɛn we de ɛp dɛn fɔ gro ɛn sheb. Dɔn dis kin mek di kansa sɛl dɛn nɔ sheb ɛn skata.
Dis drɔg kin de na di makit ɔnda di brand nem `KISQALI`. Dɛn kin yuz am mɔ fɔ mɛn bɔdi kansa.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
I rili impɔtant fɔ mek yu dɔktɔ gɛt kɔmplit pikchɔ bɔt yu wɛlbɔdi. So, bifo yu bigin dis mɛrɛsin, mek shɔ se yu tɛl yu dɔktɔ if yu gɛt ɛni wan pan di sik dɛn we de dɔŋ ya.
- If yu gɛt at sik ɔ yu dɔn gɛt at bit we nɔr de bit ɔltɛm.
- Wan infεkshכn we de naw, spεshal wan vayral infεkshכn lεk chikinpoks כ hεpi.
- If yu gɛt liva sik.
- If di nɔmba fɔ di wayt blɔd sɛl, di pletlɛt, ɔ di rɛd blɔd sɛl dɛn we de na di blɔd nɔ bɔku.
- If yu nɔ gɛt bɔku kalsiɔm, magnɛsiɔm, potashɔm, ɔ fɔsfɔr na yu blɔd.
- If yu gɛt prɔblɛm wit yu brith lɛk lɔŋ sik ɔ asma.
- If yu dɔn gɛt alɛji fɔ dis Ribociclib mɛrɛsin, ɔda mɛrɛsin, it, ɔ day.
- If yu de tray fɔ gɛt bɛlɛ ɔ yu gɛt bɛlɛ naw .
- If yu na mama we de gi pikin in bɛlɛ .
Aw a fɔ yuz di mɛrɛsin ɛksaktɔli?
As di dɔktɔ se, i rili impɔtant fɔ tek di kɔrɛkt doz di rayt tɛm.
- Swɛla dis tablɛt ɔl wit wan glas wata. Nɔ brok, krɔs, ɔ chew di tablɛt.
- Yu kin tek dis mɛrɛsin bifo ɔ afta yu it. Bɔt if yu bɛlɛ at, i go fayn fɔ tek am wit it.
- I rili impɔtant: Nɔ drink grep jus, pomegranate jus, ɔ lɛmon jus we yu de tek dis mɛrɛsin. Dɛn tin ya kin afɛkt aw di mɛrɛsin de wok.
- Gɛt di abit fɔ tek yu mɛrɛsin di sem tɛm ɛvride.
- Nɔ stɔp fɔ tek yu mɛrɛsin if yu dɔktɔ nɔ advays yu.
Wetin fɔ du if yu mis wan doz ɔ yu vɔmit?
Lɛ wi se yu mis wan doz fɔ yu mɛrɛsin. Ɔ yu bin vɔmit afta yu dɔn tek di mɛrɛsin. If dat apin, nɔ tek ɔda pil da de de. Nɔ wɔri, jɔs tek yu nɛks doz di tɛm we yu dɔn sɛtul.
Wetin a go du if a tek bɔku mɛrɛsin?
If yu tink se yu dɔn tek bɔku mɛrɛsin aksidɛntli, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital wantɛm wantɛm ɔ go na di Imejɛnsi Dipatmɛnt (ETU) na di ɔspitul we de nia yu.
Dɛn dɔn gi yu dis mɛrɛsin fɔ yu nɔmɔ. Nɔ ɛva sheb yu mɛrɛsin wit ɔda pipul dɛn.
Ɔda drɔgs dɛn we kin intarakt wit Ribociclib
Sɔm mɛrɛsin kin mek yu gɛt prɔblɛm we yu tek am wit Ribociclib, so i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud vaytamɛn ɛn ɛbul mɛrɛsin).
| Kategori fɔ drɔgs | Ɛgzampul dɛn |
|---|---|
| Nɔ tek Ribociclib wit dis mɛrɛsin. | |
| Sɔm antivayral drɔgs fɔ HIV/Epatitis | Atazanavir, Cobicistat, Darunavir, Nɛlfinavir, Saquinavir |
| Sɔm mɛrɛsin dɛn fɔ mek pɔsin gɛt kɔlɔstrel | Lovastatin, Simvastatin, ɛn ɔda pipul dɛn |
| Sɔm mɛrɛsin fɔ fungal infɛkshɔn | Flukonazɔl, Posakonazɔl |
| Difrɛn ɔda mɛrɛsin dɛn | Mεdisin dεm lεk Cisapride, Dronedarone, Pimozide, Thioridazine, Tolvaptan, Triazolam. (Ask yu dɔktɔ fɔ wan kɔmplit list) |
| Infɔm yu dɔktɔ if yu de tek Ribociclib wit dis mɛrɛsin. | |
| Mɛrɛsin fɔ fungal infɛkshɔn | Kεtokonazכl, Itrakonazכl, Vכrikonazכl |
| Mɛrɛsin fɔ mek pɔsin gɛt sik we de mek pɔsin sik | Kabamazɛpin, Fɛnitɔyn |
| Difrɛn ɔda mɛrɛsin dɛn | Klaritromaysin, Sayklɔspɔrin, Rifampin, Sɛnt Jɔn Wɔt, Takrɔlimus |
Dis list nɔr kɔmplit, so i go fayn fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛm wae yu de tek.
Tin dɛn we yu fɔ tek tɛm wit mɔ we yu de tek mɛrɛsin
- Nɔ gɛt bɛlɛ: Nɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ 3 wik afta yu dɔn stɔp di mɛrɛsin. Dis mɛrɛsin kin ambɔg pikin we nɔ bɔn yet. Dɔn bak, if di man patna insɛf de tek dis mɛrɛsin ɛn i de plan fɔ bɔn pikin, tɛl di dɔktɔ bɔt am.
- Nɔ gi yu pikin in bɛlɛ: Nɔ gi yu pikin in bɛlɛ we yu de tek di mɛrɛsin ɛn fɔ 3 wik afta yu dɔn stɔp.
- Protɛkt yusɛf frɔm infɛkshɔn: Dis mɛrɛsin kin mek yu bɔdi in imyuniti (abiliti fɔ fɛt infɛkshɔn) dɔŋ. So tray fɔ de fa frɔm pipul dɛn we gɛt fiva ɔ kol. If yu gɛt sɔm sayn dɛn lɛk fiva, bɔdi we de at, ɔ yu trot we de at, nɔ fɔ tek mɛrɛsin fɔ yusɛf ɛn kɔl yu dɔktɔ wantɛm wantɛm.
- Blɔd ɛn brus: Dis mɛrɛsin kin mek yu gɛt mɔ blɔd ɔ brus frɔm ivin smɔl injury. Tek tɛm we yu de brus yu tit ɔ sheb yu tit wit reza. Tɛl yu dɔktɔ if yu gɛt blɔd ɔ brus we nɔ kɔmɔn.
- Blɔd tɛst: Yu dɔktɔ go ɔda fɔ mek dɛn du blɔd tɛst ɔltɛm fɔ wach aw yu liva de wok ɛn aw yu blɔd sɛl dɛn de bɔku we dɛn de trit yu. Nɔ skip dɛn.
Di sayd ɛfɛkt dɛn we di mɛrɛsin kin gɛt
Lɛk ɛni mɛrɛsin, Ribociclib kin gɛt sayd ɛfɛkt. Sɔm na smɔl smɔl tin dɛn, ɛn ɔda wan dɛn nid fɔ pe atɛnshɔn to dɛn wantɛm wantɛm.
| Sayd ɛfɛkt we pɔsin kin gɛt | Tɔk bɔt |
|---|---|
| If dɛn sayn ya apin, tɛl yu dɔktɔ wantɛm wantɛm. | |
| Sivɛri Alɛji Riakshɔn | Skin rash, it, swel na di fes, lip ɔ tong. |
| Di sayn dɛm we de sho se di liva dɔn pwɛl | Dak yɔlɔ ɔ brawn urine, yu yay ɔ yu skin de yɔlɔ, pen na di rayt say na di bɛlɛ, yu nɔ de want fɔ it, yu nɔ de fil fayn. |
| Di chenj dɛn we de apin na di at rit | Chest pen, faint, tranga fɔ blo, fil lɛk yu at de bit fast ɔr nɔr de bit ɔltɛm. |
| Sayn dɛn we de sho se pɔsin gɛt di sik | Fiva, kol , kɔf, trot we de at. |
| Di sayn dɛn we de sho se pɔsin de blɔd | Brus na di skin, rɛd spat na di skin, blɔd na di urine, blak stɔl. |
| Sayd ɛfɛkt dɛm wae bɔrku tɛm nɔr kin siriɔs, bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
| Di Iɛ we De Lɔs | Ed pen, nɔs/vomit, dayarɛa ɔ kɔnstipɛshɔn. |
| Ɔda | Nɔbɔdi nɔ kin want fɔ it, yu mɔt kin gɛt wund, yu bɛlɛ kin pen, yu an ɛn fut dɛn kin swel, yu nɔ kin ebul fɔ slip. |
Aw yu fɔ kip yu mɛrɛsin?
Kip di pils usay pikin dɛn nɔ go ebul fɔ rich, na rum tɛmpracha (bitwin 20-25 sɛlshiɔs). Nɔ yuz mɛrɛsin we dɔn pas.
Kansa tritmɛnt na wan joyn. Nɔto yu wan de pan dis waka. Yu dɔktɔ, nɔs dɛn, ɛn yu fambul dɛn de wit yu. Tɔk to dɛn bɔt ɛni kwɛstyɔn, tin we de mɔna yu, ɔ tin we de mɔna yu.
Mɛsej we dɛn kin kɛr go na os
- Ribociclib na wan tritmɛnt we dɛn kin yuz fɔ mɛn bɔdi kansa. Ɔltɛm tek am jɔs lɛk aw yu dɔktɔ tɛl yu fɔ tek am.
- Bifo yu bigin fɔ tek di mɛrɛsin, tɛl yu dɔktɔ bɔt ɛni ɔda mɛrɛsin we yu gɛt ɛn ɔl di mɛrɛsin dɛn we yu de tek.
- Nɔ drink grep jus ɛn pomegranate jus ɔltogɛda we yu de tek dis mɛrɛsin.
- Wach fɔ siriɔs sayd ɛfɛkt (at ritm chenj, liva prɔblɛm, siriɔs alɛji). If yu gɛt ɛnitin we de mɔna yu, tɛl yu dɔktɔ wantɛm wantɛm.
- Nɔ gɛt bɛlɛ ɛn gi pikin in bɛlɛ we yu de trit am ɛn fɔ 3 wik afta yu dɔn stɔp.
- Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ ɛva sheb am wit ɔda pipul dɛn.
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Wetin dɛn kin yuz Ribociclib / Kisqali tablɛt fɔ?
Dis na wan mɛrɛsin we rili saksesful (Targeted therapy / CDK4/6 inhibitor) na mɛrɛsin we de kɔntrol ‘Advanced/Metastatic Breast Cancer’ ɔlsay na uman dɛn! dεn kin gi am spεshal wan wit wan כmon dכg lεk Letrozole fכ pul di rut dεm fכ di kεnsar dεm we de yuz di uman כmon ‘estrogen’ (ER-positiv / HER2-negative) fכ gro.
💬 Aw dis dכg (Ribociclib) de stכp brεst kεnsar fכ mכltiply/grכw?
Di big denja fɔ kansa, lɛk vayrɔs, na we in sɛl dɛn kin sheb kwik kwik wan ɛn gro! fכ mek wan kεnsar sεl divayd bak, tu εnzym mashin dεm (CDK4 εn CDK6) insay am fכ de wok. wetin dis pil de du na fכ go dayrekt insay di kεnsar sεl dεm εn kכmplit wan dεstroy/blכk dεn (CDK4/6) mashin dεm (Halts sεl saykl). Dɔn di kansa kin stɔp ɛn i kin day.
💬 Wetin na di siriɔs sayd ɛfɛkt dɛm we yu fɔ wach fɔ we yu de tek dis pawaful kansa mɛrɛsin?
we dεn de kil di kεnsar sεl dεm, di bכdi in ‘wayt bכdi sεl dεm/nyutrofil dεm (Neutropenia)' dεn de dכn bak (klose to nכ de). So, ivin smɔl kol kin strɔng fɔ mek yu gɛt nyumonia ɛn day! כlso, dεn pils ya kin mek di at in ilektrikal ritm ‘QT prolongation’ (ECG na mandatory). Di ɔda tin we denja na dat i kin mek di liva pwɛl (Hepatotoxicity).
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