Aw yu kin trit di inflamɛns we kin kam wit yu asma? Mek wi tok!

If yu gɛt asma, yu kin si se i nɔ kin izi fɔ yu fɔ blo sɔntɛnde. Fɔ fil tayt na yu chɛst ɛn fɔ swɛt na di men sayn dɛm fɔ asma. Di men tin we kin mek dis apin na we yu de swel insay yu aywe, ɔ wetin wi kin kɔl na mɛrɛsin `inflammation` . Dis inflamɛns kin mek yu aywe dɛn smɔl ɛn ful-ɔp wit mכkus, we kin mek i nɔ izi fɔ blo.

Wetin na di rilayshɔn bitwin asma ɛn inflamɛns?

If yu gɛt asma, yu go mɔs no se dis inflamɛns de mek di layn na yu aywe dɛn swel ɛn mek yu gɛt mɔ mכkus. Tink bɔt am lɛk wata paip we dɔn lɔk, we de mek i nɔ izi fɔ mek di wata pas. Dis inflamɛns de mek yu aywe dɛn rili sɛnsitiv. Dɔn, we sɔm tin ya (wi kin kɔl dɛn ``triggers``) lɛk dɔst, smok, ɛn animal dander go insay yu bɔdi, dɛn kin briŋ asma kwik kwik wan, we min se asma atak .

Dis na wae mek anti-inflammatory mɛrɛsin na impɔtant tritmɛnt fɔ pipul dɛm wae gɛt asma. Dɛn kin stɔp di prɔses wae kin mek asma frayd. Fɔ tɔk am simpul wan, dɛn tan lɛk we dɛn put wata pan faya.

Wetin na di tritmɛnt fɔ asma?

Difrɛn kayn mɛrɛsin de wae dɛn kin yuse fɔ kɔntrol di inflamɛns wae kin kam pan asma. Di men wan dɛn na:

• di kכtikostεroyd dεm we dεn injεkt dεn wan dεm dεn wan dεm na di rεspiretכri trakt (wi kכl dis inhala).
• Dɛn kin gi sistɛm kɔtikosterɔyd (we dɛn tek as pil ɔ injɛkt insay wan vein) fɔ afɛkt di wan ol bɔdi.
• pan tap dat, mεdikeshכn dεm de we dεn kכl ``Mast cell stabilizers'' εn ``Leukotriene modifiers''. dis dεm de εp fכ ridyus di inflameshn we ``Kכtikostεroyd'' de mek.
• wan nyu tritmεnt opshכn na ``Monoclonal antibodies'' כ ``bayolojikal tεrapi''. dis dεm de tכk bכt di sεl dεm we de involv insay inflameshn (``eosinophil sεl dεm'').

Naw lɛ wi tɔk smɔl bɔt ɛni wan pan dɛn mɛrɛsin ya .

Inhaled Corticosteroids: Na bɛst padi fɔ kɔntrol asma!

Kɔtikosterɔyd we yu inhal na di mɛrɛsin dɛn we de wok fayn pas ɔl fɔ mek yu nɔ swel ɛn mek yu nɔ gɛt bɔku bɔku wata na yu aywe . Bɔku tɛm, dis kayn inhala na di fɔs tin we dɔktɔ go gi pɔsin fɔ gɛt asma.

Wetin na di bɛnifit dɛn we pɔsin kin gɛt we i yuz dɛn tin ya?

Bɔku bɛnifit dɛn de we yu yuz dis inhala kɔrɛkt wan:

• Di simptom dɛm fɔ asma ɛn di flare-up kin ridyus.
• Short-acting beta agonists, ɔ as wi kɔl dɛn , rilieva, ɔ rescue inhalers, dɛn kin yuz am we imejensi ɛn ridyus di nɔmba fɔ di tɛm we yu nid fɔ yuz dɛn.
• Yu lɔng dɛn kin wok fayn.
• Di nid fɔ go na imejensi rum ɛn fɔ de na ɔspitul go stɔp.
• Ɔl togɛda, dɛn kin kɔntrol asma fayn fayn wan.

Impɔtant: Yu fɔ mɛmba dɛn tin ya we yu de yuz dɛn tin ya!

I impɔtant fɔ no se dɛn stɛroyd ya we pɔsin kin inhal kin jɔs mek pɔsin nɔ gɛt asma, nɔto fɔ pul di sik dɛn we dɔn de . Dis min se if yu tek dɛm we yu gɛt asma atak, yu nɔ go gɛt rilif wantɛm wantɛm. Na dat di riliva inhala de fɔ.

Dis ``kɔntrola`` inhala (as wi kɔl am) fɔ yuz ɛvride, lɛk aw yu dɔktɔ tɛl yu . Fɔ sɔm, i kin bi tu tɛm insay di de, fɔ ɔda wan dɛn, wan tɛm insay di de. I nɔ fayn fɔ ridyus ɔ stɔp fɔ yuz dɛn tin ya we yu nɔ tɔk to yu dɔktɔ, ɛn tink se yu sik dɛn de bɛtɛ. If yu du dat, dat kin mek yu asma wɔs bak.

Wetin na dɛn nos kɔtikosterɔyd ya?

Bɔku difrɛn kayn kɔtikosterɔyd dɛn de we pɔsin kin inhal na di makit. Sɔm ɛgzampul dɛn na:

• ``Bɛklɔmɛtazɔn dipropionɛt (Qvar RediHaler®)''.
• `Budesonide (Pulmikort®; Simbikɔt®)`. (Dis `(Symbicort®)` na wan kɔmbaynshɔn fɔ `(budesonide)` ɛn `(formoterol)`.)
• `Siklisɔnayd (Alvesko® HFA)`
• `Flutikason (Flovent® HFA; Advair® HFA ɛn diskus, Wixela® Inhub, AirDuo®)`. (Dεn wan ya gεt `(flutikason)` εn `(salmeterol)`.)
• Flutikason furoat (Arnuity® Ɛlipta; Breo® Ɛlipta; Trelegy® Ɛlipta). (Breo® gɛt fluticasone furoate ɛn wan beta agonist we de wok fɔ lɔng tɛm we dɛn kɔl vilanterol. Trelegy® gɛt umeclidinium apat frɔm dɛn tu ya.)
• ``Flutikason propionεt (ArmonAir® RespiKlik)''.
• `Mɔmɛtasɔn (Asmanɛks®, Dulera®)`. (`(Dulera®)` gɛt `(mometasone)` wit `(formoterol)`.)

Aw dɛn kayn tin ya we dɛn kin yuz fɔ blo kin kam?

dis ``(inhaled corticosteroids)`` de kam insay tri men fכm dεm:

1. `(Metered Dose Inhaler - MDI)`: Dis na di kayn we we tan lɛk smɔl tin, ɛn yu de yuz am pan tap. We yu de yuz dis, i bɛtɛ fɔ yuz am wit `(valved holding chamber)` ɔ `(spacer)` (sɔntin we wi kɔl 'intermediate chamber' insay Sinhala). dis `(spacer)` de εp di mεdisin fכ go dayrekt to di lכng dεm, εn i de ridyus di mεdisin we de dכn na di mכt εn trot. Dis tan lɛk we yu de yuz tiub we yu de sprɛy wata frɔm watasay.

2. `(Dry Powder Inhaler - DPI)`: Dis kin gɛt di mɛrɛsin we tan lɛk dray pauda. Dɛn kin yuz am bay we dɛn tek dip briz insay.

3. `(Nebulizer solutions)`: Dis kin kam as likwid. I de vaypa ɛn inhal am yuz smɔl mashin (`(nebulizer mashin)`). Bɔku tɛm dɛn kin yuz dis we fɔ yɔŋ pikin dɛn ɛn di wan dɛn we gɛt siriɔs asma.

A fɔ fred fɔ yuz dɛn tin ya? Ɛni bad bad tin dɛn de we kin apin to am?

Kɔtikosterɔyd we dɛn kin inhal na mɛrɛsin we rili sef fɔ big pipul ɛn pikin dɛn . Di sayd ɛfɛkt dɛn nɔ kin bɔku, mɔ we dɛn yuz am smɔl.

Bɔt nɔ kin apin so ɔltɛm, if yu yuz dɛn bɔku bɔku wan, fɛns infɛkshɔn na yu mɔt (thrush) kin kam, ɛn yu vɔys kin chenj (i kin mek yu vɔys ala). Dis kin rili izi fɔ mek dɛn nɔ du dis. Afta ɛni tɛm we yu yuz di inhala , was yu mɔt fayn fayn wan, gargle, ɛn spit di mɛrɛsin . If yu yuz MDI, yu kin ridyus dis risk bak bay we yu yuz spɛshal say. If yu aksidɛntli gɛt thrush, yu kin trit am izi wan wit wan anti-fungal mouthwash we yu dɔktɔ gi yu.

Aw dɔktɔ kin gi dɛn tin ya?

Yu dɔktɔ go tray ɔltɛm fɔ gi yu di smɔl doz fɔ dis mɛrɛsin we go kɔntrol yu asma. Bɔrku pipul kin frayd wae dɛn yɛri di wɔd "steroids." Dis na bikɔs dɛn dɔn yɛri bɔt anabolic steroids, we atlet dɛn kin yuz fɔ bil mɔsul. Bɔt stɛroyd fɔ asma nɔ tan lɛk dat . Dɛn na mɛrɛsin dɛn we de mek pɔsin nɔ gɛt sik. Infakt, if yu tek dɛn ɛvride, dat kin ɛp fɔ kɔntrol yu asma.

Sistem Kɔtikosterɔyd: Ɛp fɔ siriɔs asma!

Dɛn ``Systemic corticosteroids`` ya na mɛrɛsin dɛm wae dɛn kin yuse fɔ trit siriɔs asma episɔd dɛm. Dɛn kin gi dɛn as pils ɔ likwid (``oral``), ɔ dɛn kin gi dɛn insay di bɔdi tru wan vein (``intravenous - IV``).

Us tɛm dɛn kin gi dɛn tin ya?

Dɛn kin yuse dis mɛrɛsin wit ɔda mɛrɛsin fɔ kɔntrol asma atak wae kin kam kwik kwik wan, ɔr fɔ trit asma wae kin teik lɔng tɛm, wae nɔr kin izi fɔ kɔntrol.

Aw dɛn tin ya kin bigin fɔ wok?

Sεstεmik stεroyd dεm de tek lεk tri awa fכ bigin wok, wit di bεst risכlt we dεn kin si afta siks to twεlv awa. Sɔntɛnde dɛn kin gi dɛn bɔku bɔku dez fɔ sɔm dez (dɛn kin kɔl am stɛroyd bɔrst), ɔ dɛn kin ridyus di doz smɔl smɔl as tɛm de go (dɛn kin kɔl am stɛroyd taper). Sɔntɛnde, fɔ kɔntrol fɔ lɔng tɛm, dɛn kin gi dɛn smɔl smɔl ɛvride ɔ ɛvri ɔda de.

Wetin na dɛn kayn `(Systemic Steroids)` ya?

difrεn kayn ``sistεmik stεroyd dεm'' de we dεn kin yus (dεn wan ya de bak as ``jεnεrik'' prodakt):

• `Kɔrtizɔn asɛtat`
• `Dɛksamɛtazɔn`
• `Haydrokɔtizɔn (Kɔrtɛf®)`
• `Mεtilprεdnisolon (Mεdrכl®, Sכlu-Mεdrכl®, Dεpo-mεdrol®)`
• `Prednisɔn (Dɛltasɔn®)`
• `Prεdnisolon (Prεlכn®, Pεdiaprεd®, Ɔraprεd®)`

Yu tink se wi fɔ no bak bɔt di bad tin dɛn we kin apin to wi?

di sayd ifekt dεm fכ sistεmik stεroyd dεm kin apin we dεn yuz am fכ lכng tεm . Dɛn sayd ɛfɛkt ya kin bi:

• Akni we gɛt akni.
• We yu de gɛt mɔ wet.
• Chenj na di we aw pɔsin de fil ɔ di we aw i de biev.
• Bɛlɛ we de at (e.g. gastritis).
• Bɔn wik, bon we de lɔs.
• di yay kin chenj, fכ egzampl glaukoma (we di ay prεshכn kin bכku) כ katarakt (di yay kin kכlכd).
• (Pikin dɛn nem) growth retardation.

Bɔt mɛmba se dɛn bad bad tin ya nɔ kin apin so ɔltɛm we dɛn yuz am fɔ shɔt tɛm . Yu fɔ yuz dɛn fɔ shɔt tɛm nɔmɔ we yu asma rili bad. If yu gɛt asma we yu nɔ ebul fɔ kɔntrol ɛn yu nid fɔ yuz stɛroyd fɔ lɔng tɛm, yu fɔ go to dɔktɔ we de mɛn yu pulmonɔn ɔ dɔktɔ we de mɛn alɛji. Dɛn kin ɛp yu fɔ disayd fɔ gɛt mɔ advans tritmɛnt ɛn sɛn yu to ɔda spɛshal pipul dɛn if nid de.

Leukotriene Modifiers: Na ɔda ɛp!

Wetin na dɛn tin ya? Aw dɛn kin wok?

Lukotrien na kεmεkal dεm we de apin na wi bכdi nכmal wan. Dɛn kin mek di mɔsul dɛn na wi aywe dɛn tayt ɛn mek di mכkus prodyuz bכku. Lukotrien modifya dεm de blכk di akshכn fכ di lukotrien dεm. Stɔdi dɔn sho se dɛn mɛrɛsin ya kin ɛp fɔ mek yu ebul fɔ blo fayn ɛn fɔ mek yu nɔ gɛt asma. Dɛn kin kam lɛk tablɛt dɛn. Dɛn kin tek dɛn wan ɔ tu tɛm insay di de. Yu kin ebul fɔ ridyus di ɔda mɛrɛsin dɛn we yu nid fɔ tek asma.

Wetin na di kayn `(Leukotriene Modifiers)`?

Di drɔgs dɛn we de insay dis kategori na:

• `Mɔntɛlukast (Singulair®)`
• `Zafirlukast (Akɔlat®)`
• `Zileuton (Zyflo®)`

Ɛni bad bad tin dɛn de we kin apin to am?

Di sayd ɛfɛkt dɛm we kin apin pas ɔl na ed we kin at ɛn nɔs. Lukotrien modifya kin intarakt bak wit sɔm ɔda mɛrɛsin dɛm (fɔ ɛgzampul, di asma mɛrɛsin tiofilin ɛn di blɔd tina warfarin). So i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek.

Monoclonal Antibodies - Biologic Therapy: Nyu op fɔ siriɔs asma!

Monoclonal antibodies na wan kayn bayolojikal tεrapi we dεn kin yus fכ trit siriכs asma. Dɛn kin wok bay we dɛn de blok di bɔdi in rεspכns to trigεr dεm we de mek inflameshn. dεn de tכk bכt di sεl dεm we de pat pan wi imyun sistεm, lεk di eosinophil sεl dεm.

Bɔku kayn mɛrɛsin ya de. Dɛn kin gi dɛn as injɛkshɔn ɔnda di skin na dɔktɔ in ɔfis, as IV infushɔn na klinik ɔ ɔspitul, ɔ sɔm dɛn kin injɛkt dɛnsɛf na os. Pipul dεm wae de tek dεn bayolojikal dεm ya kin gεt tritmεnt εvri 2 to 8 wik (dipכnd pan di bayolojikal). Yu go nid fɔ de ɔnda di kia fɔ pulmonɔlɔjis ɔ alɛrgist if yu de tek dɛn mɛrɛsin ya.

Mast Cell Stabilizers: Na Drug we dɛn nɔ kin yuz ɔltɛm

di mast sel stεbyulayz dεm de wok bay we dεn de blכk di rilis fכ histamin εn כda inflammatory sכbstans dεm frכm di mast sεl dεm. Bɔt dɛn nɔ kin yuz dɛn tin ya fɔ mɛn asma.

Wetin yu nid fɔ mɛmba pas ɔl!

Asma na wan sik wae de mek yu nɔr de blo fayn fayn wan (dat na, wae de kɔntinyu fɔ de) na di say dɛm wae de blo na yu lɔng dɛm. I kin tan lɛk smɔl spak we de insay ɔltɛm. So, if yu tek di mɛrɛsin dɛm wae yu dɔktɔ dɔn gi yu, yu kin kɔntrol yu asma fayn fayn wan ɛn mek yu gɛt wɛl bɔdi fɔ lɔng tɛm.

Mɛmba se fɔ liv wit asma kin tranga, bɔt if yu gɛt di rayt tritmɛnt, yu kin liv nɔrmal, aktif layf. Tɔk to yu dɔktɔ ɛn mek wan tritmɛnt plan we go wok fɔ yu. Na di bɛst we fɔ blo fayn fayn wan!

` Asma, Inflameshɔn, Inhala, Kɔtikosterɔyd, Tritmɛnt, Respiratory Disease