Bɔku tɛm yu kin fil taya ɛn yu nɔ gɛt layf? Sɔntɛnde wi kin tink se dis na nɔmal tin, we kin mek wi taya we wi de wok pasmak. Bɔt, siriɔs rizin kin de we ayd ɔnda dis taya. Tide wi go tɔk bɔt dis kayn anemia, ɔ wan spɛshal kɔndishɔn we gɛt fɔ du wit blɔd we nɔ de na di bɔdi. Dɛn kɔl dis Heinz Bɔdi Anemia.
Fɔ tɔk am simpul wan, wetin na dɛn Heinz Bɔdi ya?
Fɔ ɔndastand dis, wi fɔ no smɔl bɔt wi blɔd fɔs. Wi blɔd gɛt wan kayn sɛl we dɛn kɔl rɛd blɔd sɛl. Dis na di sɛl dɛn we de kɛr ɔksijɛn go ɔlsay na wi bɔdi. Tink bɔt dɛn rɛd blɔd sɛl ya as smɔl smɔl trak dɛn we de kɛr ɔksijɛn. Di men pat pan dɛn trak ya we de kɛr ɔksijɛn na in dɛn kɔl ɛmoglobin . Dis prɔtin we dɛn kɔl ɛmoglobin na in de gi wi blɔd in rɛd kɔlɔ.
Bɔt fɔ sɔm rizin, dɛn ɛmoglobin mɔlyul ya kin pwɛl. Jɔs lɛk aw di lod dok na trak kin pwɛl. Di ɛmoglobin we dɔn pwɛl kin gɛda togɛda, gɛda togɛda, ɛn stik na di wɔl na di rɛd blɔd sɛl. Wi kin kɔl dɛn klɔmp dɛn de Heinz Bodies .
Dɛn Heinz bɔdi ya kin mek di rɛd blɔd sɛl dɛn nɔ ebul fɔ chenj ɛn dɛn kin stif. Nɔmal wan, i izi fɔ mek di rɛd blɔd sɛl dɛn we gɛt wɛlbɔdi kin pas ivin di blɔd vesel dɛn we tan pas ɔl. Bɔt i nɔ kin izi fɔ dɛn sɛl dɛn ya we stif fɔ du dat. Wi splin na wan ɔgan we de klin wi blɔd. as i de pas tru dis filta, di splin de no di rεd bכdi sεl dεm wit dεn stif Heinz bכdi dεm ya εn i de pwεl dεm. Sɔntɛnde, na di Heinz bɔdi pat nɔmɔ dɛn kin pul, ɛn di rɛd blɔd sɛl dɛn kin tan lɛk se pɔsin dɔn bit wan pat pan biskit. Wi kin kɔl dɛn bayt sɛl ya bak .
Dis we ya, we dɛn rɛd blɔd sɛl ya we dɔn pwɛl kin brok kwik kwik wan pas aw wi bɔdi kin mek nyu wan dɛn, di blɔd we de na wi bɔdi kin go dɔŋ. Na dat wi kin kɔl Heinz Bɔdi Anemia.
Wetin mek dis tin kin apin? Wetin na di rizin dɛn?
di men tin we de mek Heinz bodi dεm na kεmikכl כ כksidεtiv damej to wi rεd bכdi sεl dεm. Dis kin gɛt am afta dɛn bɔn am, ɔ i kin bi bikɔs ɔf wan sik we dɛn bɔn wit.
Kɔz dɛm we kin apin afta dɛn bɔn am
Dɛn tin ya kin apin mɔ frɔm tin dɛn we de kam insay di bɔdi frɔm ɔdasay.
| Rizin | Diskripshɔn ɛn ɛgzampul dɛn |
|---|---|
| Sɔm drɔgs ɛn kemikal dɛn | If pɔsin tek sɔm mɛrɛsin ɛn kemikal dɛn, i kin pwɛl di rɛd blɔd sɛl dɛn. Ɛgzampul dɛn:
|
| Minral we nɔ de wok fayn | Selenium na impɔtant minral fɔ wi bɔdi. I de ɛp fɔ mek wan pawaful antiɔksidant we dɛn kɔl glutathione. Dis antiɔksidant na in de protɛkt wi rɛd blɔd sɛl dɛn fɔ mek dɛn nɔ pwɛl. if di sεlεnium dεfichεns de, dis protεkshכn de rεdכks εn di Heinz bכdi dεm kin fכm. |
Di tin dɛn we kin mek dɛn bɔn pikin (di tin dɛn we kin apin to pɔsin we gɛt jɛnɛtiks) .
Dis na jεnεtik kכndyushכn dεm we mama εn papa kin gεt frכm pikin dεm.
- G6PD dεfisiεns: di ful nem fכ dis na Glucose-6-phosphate dehydrogenase dεfisiεns. Dis na kɔndishɔn we dɛn kin si bak na wi kɔntri. dis G6PD na wan rili imכtant εnzym we de protεkt rεd bכdi sεl dεm. pan pipul dεm we nכ gεt dis εnzym, we dεn tek sכm mεdikeshכn, we dεn gεt sכm infεkshכn, כ we dεn it sכm it dεm (e.g. fava bins), dεn rεd bכdi sεl dεm kin bigin fכ brok kwik kwik wan.
- Thalassemia: Dis na bak wan jenɛtik dɛfekt we de mek ɛmoglobin we kɔmɔn na wi kɔntri. Yu kin si Heinz bɔdi bak na di blɔd fɔ di wan dɛn we gɛt thalassemia.
- Ɛmoglobinopathies we nɔ stebul: Dɛn kin bɔn sɔm pipul dɛn wit abnɔmal, nɔ stebul fɔm dɛn fɔ ɛmoglobin. Dɛn tin ya kin pwɛl izi wan ɛn kin mek Heinz bɔdi dɛn.
Yu gɛt dɛn sik ya bak?
Di prɛzɛns fɔ Heinz bɔdi nɔ de kɔz di simptom dɛm. Bɔt we bɔku bɔku rɛd blɔd sɛl dɛn bigin fɔ brok, anemia kin kam ɛn difrɛn sayn dɛn kin sho.
| Kɔmɔn simptom dɛm fɔ Heinz bɔdi anemia | |
|---|---|
| Di skin ɛn yay we de yɔlɔ (Jaundice) . | Bɔku tɛm, yu kin fil se yu taya pasmak ɛn yu kin taya |
| I nɔ izi fɔ blo ɛn swɛt | Pale skin |
| At nɔ kin bit ɔltɛm ɔ i kin bit kwik kwik wan | Liva ɔ splin we swɛl (pen na di ɔp pat na di bɛlɛ) . |
Aw yu rili si dis? Us tɛst dɛn dɛn kin du?
If yu gɛt sayn dɛn lɛk dis, di fɔs tin we yu dɔktɔ go du na fɔ chɛk yu ɛn ɔda fɔ mek dɛn du sɔm blɔd tɛst.
- Complete Blood Count (CBC): Dis de sho di nɔmba fɔ di rɛd blɔd sɛl dɛn, di wayt blɔd sɛl dɛn, ɛn di pletlɛt dɛn we de na yu blɔd. Dis impɔtant fɔ chɛk fɔ si if pɔsin nɔ gɛt bɛtɛ blɔd.
- Ɛmoglobin ɛn Ɛmatokrit: Dis kin mɛzhɔ bak di nɔmba fɔ di rɛd blɔd sɛl dɛn ɛn di ɛmoglobin lɛvɛl.
- Peripheral Blood Smear: Dis na tɛst we rili impɔtant. Na ya, dɛn kin smɛl wan drɔp blɔd pan glas slayd ɛn chɛk am ɔnda maykroskɔp. Dɔn, yu kin si di shep ɛn saiz fɔ di rɛd blɔd sɛl dɛn. di "bayt sel dεm" we wi bin tכk bכt fכs yu kin si am bak wit dis tεst. Fɔ si Heinz bɔdi dɛn dairekt wan, dɛn fɔ yuz spɛshal day (stain) fɔ dis tɛst.
- Yurin tɛst: We di rɛd blɔd sɛl dɛn brok, di ɛmoglobin kin kɔmɔt na di urine. Dɛn kin du dis tɛst fɔ si if i de.
Wetin na di tritmɛnt dɛn?
Di tritmɛnt dipen pan wetin mek di sik de. Yu dɔktɔ go no wetin mek i apin ɛn gi yu di tritmɛnt we fit pas ɔl.
- Fɔ stɔp di mɛrɛsin we de mek pɔsin gɛt di sik: If dɛn no se na wan mɛrɛsin de mek di sik, dɛn go stɔp da mɛrɛsin de ɛn if nid de, dɛn go gi am mɛrɛsin we sef insted.
- Fɔ gi nyutrishɔn sɔpɔtmɛnt: If dis kɔndishɔn kɔmɔt frɔm we yu nɔ gɛt minral lɛk sɛlɛniɔm, dɛn go gi sɔpɔtmɛnt fɔ dat.
- Antibayɔtik: If anemia de wɔs bikɔs ɔf infekshɔn.
- Blɔd Transfyushɔn: If anemia bad bad wan, dɛn kin nid fɔ transfyushɔn blɔd fɔ mek di blɔd kam bak kwik kwik wan.
- Fɔ pul di splin: Sɔntɛnde, dɛn kin se dɛn fɔ du ɔpreshɔn fɔ pul di splin, we na di men say we di rɛd blɔd sɛl dɛn kin pwɛl.
- Dɛn kin yuz tritmɛnt dɛn lɛk mɛrɛsin we de stɔp di imyun ɛn we dɛn kin transplant stem sɛl bak pan kes dɛn we nɔ kin apin so ɔltɛm ɛn we kin rili bad.
Di tin we impɔtant pas ɔl: Nɔ ɛva stɔp fɔ tek ɛni mɛrɛsin ɔ chenj di doz we yu nɔ tɔk to yu dɔktɔ. I kin denja.
Us kɔmplikɛshɔn kin apin bikɔs ɔf dis kɔndishɔn?
If dɛn nɔ de manej di Heinz bɔdi anemia fayn fayn wan, sɔm prɔblɛm dɛn kin apin. Dɛn tin ya kin difrɛn difrɛn wan fɔ di kɔz ɛn aw fɔ trit di sik.
- Blɔd we de klɔt (espɛshali na di lɔng) .
- Ston dɛn we de na di gal blad
- Kidni we nɔ de wok fayn
- At we nɔ de wok fayn
- Shok we i mek
- Di sayd ɛfɛkt dɛm fɔ di mɛrɛsin dɛm we dɛn tek fɔ tritmɛnt
Sɔm pan dɛn prɔblɛm ya na di mɛdikal imejensi. So, if yu nɔ fil fayn wantɛm wantɛm, i nɔ izi fɔ yu fɔ blo bad bad wan, ɔ yu gɛt pen na yu chɛst, go na di Imejɛnsi Dipatmɛnt (ETU) na di ɔspitul we de nia yu wantɛm wantɛm. If yu tink se dis sik dɔn kam bikɔs yu it wan kemikal, yu kin kɔl bak di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital fɔ advays.
Mɛsej we dɛn kin kɛr go na os
- Heinz Body Anemia na wan sik wae de bodi de brok dכn rεd blɔd sεl dεm fast fast pas aw i kin mek nyu wan dεm.
- Dis kin bi bikɔs ɔf sɔm mɛrɛsin, kemikal, ɔr tin wae dɛn kin bɔn wit lɛk G6PD dɛfisiɛns ɛn thalassemia.
- Di men sayn dɛm na fɔ taya ɔltɛm, yu skin kin yɔlɔ, ɛn yu kin gɛt pal.
- I impɔtant fɔ du blɔd tɛst fɔ no if pɔsin gɛt dis sik kɔrɛkt wan.
- Di tritmɛnt de dipen pan wetin de mek yu gɛt di sik, so i rili impɔtant fɔ go to dɔktɔ fɔ advays.
- Nɔ stɔp fɔ tek ɛni mɛrɛsin we yu nɔ go to dɔktɔ. If yu gɛt ɛnitin we nɔ izi fɔ yu, go to yu dɔktɔ wantɛm wantɛm.
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