Bw’ozuulibwa nti olina kookolo w’amabeere, omusawo ajja kukola ebigezo ebiwerako okumanya ebisingawo ku butoffaali bwa kookolo. Kino kitera okukolebwa nga batwala ekitundu ku bitundu bya kookolo nga bayita mu kulongoosebwa oba okukebera ebitundu by’omubiri. Ekimu ku bigezo bino kwe kulaba oba obutoffaali bwa kookolo bulina ‘ hormone receptors ’. Lowooza ku bikwata bino nga ‘ebizibiti’ ebitonotono ku ngulu w’obutoffaali. ‘Ebisumuluzo’ ebiyitibwa obusimu bwe biyingira mu kkufulu zino, obutoffaali bufuna obubaka okukula.
Progesterone busimu obukolebwa mu butonde mu mibiri gyaffe. Kikulu nnyo ku bintu ng’obuvubuka, okugenda mu nsonga, n’okufuna embuto mu bakyala. Obutoffaali obumu obwa kookolo w’amabeere bulina ebikwata ku busimu buno. Ekika kya kookolo kino ayitibwa kookolo w’amabeere progesterone-receptor positive, oba simply PR-positive (PR+). Ekibaawo mu mbeera eno kwe kuba nti obusimu obuyitibwa progesterone bujja ne bukwatagana n’obutoffaali bwa kookolo ne bubuyamba okwongera okukula. Kale, obujjanjabi bwa kino bugezaako okuyimiriza enkola eno ey’obusimu.
Obusimu obulala obukola mu ngeri y’emu ye estrogen. Singa obutoffaali bwa kookolo buba n’ebikwata estrogen, kiyitibwa kookolo wa estrogen-receptor positive, oba ER-positive (ER+).
Ani ali mu bulabe obw’amaanyi olw’embeera eno?
Singa obutoffaali bwa kookolo wo buba bwa PR-positive, ER-positive oba byombi, kitera okuyitibwa kookolo w’amabeere hormone-receptor positive (HR+). Ekirungi nti kookolo w’amabeere nga 7 bokka ku 10 abazuuliddwa be ba kika kino. Wadde kookolo ow’ekika kino asobola okukwatibwa ku myaka gyonna, asinga kubeera mu bakyala abayise mu nsonga.
Okutwaliza awamu, ensonga ze zimu ez’akabi ezikwata kookolo yenna ow’amabeere nazo zikwata ne kookolo alina HR-positive. Ka tulabe kiki kye bali.
| Ensonga y’akabi | Mu ngeri ennyangu... |
|---|---|
| Okubeera omukazi | Abakyala bali mu bulabe bwa maanyi bw’ogeraageranya n’abasajja. |
| Okukaddiwa | Obulabe bweyongera n’emyaka. |
| Ebitali bya bulijjo mu butoffaali bw’amabeere | Bw’oba nga emabegako walina okukula kw’obutoffaali okutali kwa bulijjo mu mabeere (e.g. LCIS ). |
| Ebyafaayo by’amaka | Singa omuntu ow’omu maka ow’oku lusegere aba alina kookolo w’amabeere. |
| Okutuuka mu myaka gy’obuvubuka nga bukyali | Okugenda mu nsonga kutandika nga tannaweza myaka 12. |
| Okuzaala abaana ekikeerezi | Okuzaala omwana wo asooka oluvannyuma lw’emyaka 35 oba obutafuna lubuto. |
| Okuva mu nsonga nga kikeeredde | Okuva mu nsonga oluvannyuma lw’emyaka 55. |
| Okumira obujjanjabi bw’obusimu | Okumira eddagala erikyusa obusimu oluvannyuma lw’okuggwaamu amaanyi. |
Obubonero bwe buliwa?
Ebiseera ebisinga abakyala abasinga tebalina bubonero bwonna bwe bazuuliddwa nga balina kookolo w’amabeere. Wabula, kizuulibwa mu butanwa nga bakeberebwa amabeere aga bulijjo.
Obubonero bwa kookolo w’amabeere alina HR-positive bufaananako n’obw’ebika bya kookolo w’amabeere ebirala . Bino bye bimu ku bubonero obusinga okulabika.
| Obubonero | Kino kifaayo. |
|---|---|
| Ekizimba ekipya mu bbeere | Ekizimba kyonna ekipya ky’osobola okuwulira, ne bwe kiba nga tekiruma. |
| Okuzimba mu bbeere | Okuzimba ebbeere lyonna oba ekitundu kyalyo. |
| Obulumi mu mabeere oba enfuli | Obulumi obutali bwa bulijjo, obutasalako. |
| Olususu lukyuka | Olususu olubbira, okulabika ng’ebikuta by’emicungwa, olususu okugonvuwa, okumyuuka oba olususu olukalu, oluliko ebikuta. |
| Enfuli zikyuka | Enfuli efuuka indented oba okufulumya amazzi. |
| Ennywanto z’omusaayi ezizimba | Ebizimba mu nnyindo oba mu bulago ebiyinza okukwatibwa mu ngalo. |
Obujjanjabi bw’obusimu bukozesebwa butya?
Bw’oba okola enteekateeka yo ey’obujjanjabi, omusawo wo ajja kulowooza ku mbeera y’obusimu bwa kookolo wo. Obujjanjabi bwa hormone bwe bujjanjabi obukulu era obukulu eri kookolo alina PR. Ekigendererwa kwe kutangira obutoffaali bwa kookolo okukozesa obusimu okukula.
Mu ngeri ennyangu, obujjanjabi bw’obusimu busalako ‘emmere’ (obusimu) kookolo gy’ayagala.
Kino kiyinza okukolebwa mu ngeri bbiri enkulu:
- Okulongoosa okuggyamu enkwaso : Kino kikendeeza ku busimu bw’omubiri.
- Empeke oba empiso ezijjanjaba obusimu: Eddagala lino liremesa omubiri okukola obusimu, oba liziyiza ebikwata (ebizibiti) ku butoffaali bwa kookolo, ne liziyiza okusiba ku busimu (ebisumuluzo).
Ekika ky’obujjanjabi bw’obusimu bw’ofuna nakyo kijja kusinziira ku oba oyise mu nsonga. Obujjanjabi buno busobola okukozesebwa ku mutendera gwonna ogwa kookolo. Okusinziira ku mutendera gwa kookolo, obujjanjabi bw’obusimu buweebwa wamu n’obujjanjabi obulala, gamba ng’okulongoosa oba eddagala eriweweeza ku bulwadde.
Bujjanjabi obulala bwe buruwa?
Ng’oggyeeko obujjanjabi bw’obusimu, oyinza okuweebwa ekimu oba ebisingawo ku bino wammanga ku kookolo w’amabeere alina PR .
- Okulongoosa: Okulongoosa okuggyamu obutoffaali bwa kookolo. Okugeza, okuggyawo ekizimba kyokka (`Lumpectomy`) oba okuggyawo ebbeere lyonna (`Mastectomy`).
- Chemotherapy: Eddagala ery’amaanyi eriweebwa okusaanyaawo obutoffaali bwa kookolo.
- Radiation therapy : Ekozesa emisinde egy’amaanyi amangi okusaanyaawo obutoffaali bwa kookolo bwonna obusigaddewo.
- Targeted Therapy: Eddagala erigenderera obutoffaali obw’enjawulo obuyamba obutoffaali bwa kookolo okukula. Bino era bisobola okwongera ku bulung’amu bw’obujjanjabi bw’obusimu.
Prognosis eri etya?
Wano waliwo amawulire amalungi gy'oli. Kookolo ayitibwa hormone-receptor-positive (HR+) atera okukula mpola okusinga kookolo alina hormone-receptor-negative (HR-Negative). Ekirala, olina enkizo mu bujjanjabi kubanga busobola okuziyiza enkola y’obusimu n’okukomya kookolo okukula. Kyokka nga bwe kiri ku kookolo yenna, okuwona mu biseera eby’omu maaso kisinziira ku ngeri gy’azuulibwamu amangu.
Naye waliwo ekintu eky'okujjukira. Wadde ng’obujjanjabi bw’obusimu busobola okufuga okukula n’okusaasaana kwa kookolo, oluusi buyinza okubaawo oluvannyuma lw’emyaka mingi ng’amaze okujjanjabwa. Eno y’ensonga lwaki abasawo oluusi bawa obujjanjabi bw’obusimu okumala ebbanga eddene, oluusi okumala emyaka 5 oba 10.
N’olwekyo, kikulu nnyo okwogera mu lwatu era mu bulambulukufu n’omusawo wo ku mbeera y’obusimu obukwata kookolo wo n’engeri gy’anaakosaamu enteekateeka yo ey’obujjanjabi n’ekkubo ly’okugenda mu maaso.
Obubaka Obutwala Awaka
- Kookolo w’amabeere PR-Positive (PR+) kitegeeza nti obutoffaali bwa kookolo bukozesa obusimu obuyitibwa progesterone okukula.
- Kookolo ow’ekika kino atera nnyo naddala ng’ovudde mu nsonga.
- Obujjanjabi bwa hormone nkola ya bujjanjabi ekola nnyo era enkulu ekozesebwa ku kino.
- Okutwalira awamu enteekateeka y’okuteebereza kookolo ono nnungi kubanga akula mpola, naye obujjanjabi obw’ekiseera ekiwanvu n’okukeberebwa abasawo buli kiseera kyetaagisa okuziyiza okuddamu okulwala.
- Tolonzalonza kwogera na musawo wo ku mbeera yo, obujjanjabi, n’ebikweraliikiriza byonna by’oyinza okuba nabyo.
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