Ekibuuzo ekimu ekijja mu birowoozo waakiri omulundi gumu mu birowoozo by’omuntu yenna agenda okujjanjabibwa kookolo w’amabeere kiri nti, ‘Obulwadde buno kati buweddewo ddala?’. Okutya okwo kwa magezi nnyo. Naye ekirungi nti ebiseera ebisinga, kookolo w’amabeere takomawo. Kyokka, oluusi kisobola.
Bwe kidda, tukiyita ' okuddamu' . Waliwo engeri eziwerako kino gye kiyinza okubaawo. Ekimu kwe kudda mu mabeere ge gamu ne kookolo eyasooka oba mu kitundu ekiriraanyewo. Oluusi kiyinza okusaasaana mu nnywanto eziriraanyewo. Oluusi, kiyinza okusaasaana mu bitundu by’omubiri eby’ewala, gamba ng’amagumba oba amawuggwe.
Omusawo essira aliteeka ku ki?
Okuva lwe wasooka okuzuulibwa nti olina kookolo w’amabeere, abasawo bajja kukebera ensonga ezikyongera obulabe bw’okumuddamu. Amawulire gano gajja kubayamba okusalawo obujjanjabi obusinga okukuyamba.
"Tetusobola kugamba na bukakafu 100% nti kookolo ajja kudda. Naye kati tusobola okukiragula n'emikisa mingi nnyo okusinga edda," omukugu bw'agamba.
Wabaddewo enkulaakulana ennene mu mulimu guno mu myaka 10 egiyise naddala mu kookolo alina estrogen -receptor positive.
Mu ngeri ennyangu, ekizimba gye kikoma okuba ekinene, gye kikoma okusaasaana mu bitundu ebirala, emikisa gy’okuddamu okuddamu. Ate era, ebiramu bya kookolo kikulu nnyo. Kwe kugamba, biki ebitongole ebikwata ku butoffaali bwa kookolo. Okugeza, ekika kya kookolo w'amabeere ayitibwa ``triple-negative'' (kwe kugamba, kookolo atalina bikozesebwa byonna ebisatu ebya estrogen, progesterone, ne HER2) atera okuddamu.
| Ebintu by’olina okulowoozaako ng’okebera akabi | Lwaki ekyo kikulu? |
|---|---|
| Emyaka gyo n’okumanya oba oyise mu nsonga | Emyaka n’obusimu bisobola okukosa akabi. |
| Sayizi y’ekizimba | Okutwalira awamu ebizimba ebinene bikwatagana n’obulabe obw’amaanyi obw’okuddamu okulwala. |
| Oba esaasaanidde mu nnywanto z’omusaayi | Okubeerawo kw’obutoffaali bwa kookolo mu musulo kiraga nti kookolo asobola okusaasaana. |
| Embeera y’abaweereza (receptor status) eya kookolo | Obujjanjabi n’akabi byawukana okusinziira ku oba kookolo alina ER-positive, PR-positive, HER2-positive, oba triple-negative. |
Ebigezo eby’enjawulo ebitunuulira ennyo akabi
Oluusi, singa kookolo aba munene nnyo oba ng’asasaanye n’ennywanto, kizibu okwogera ddala akabi akali. Kino abasawo bakiyita ‘gray zone.’
Mu mbeera nga zino, waliwo ebigezo eby’enjawulo ebiyinza okuwa ebisingawo . Wabula okukeberebwa kuno kwonna tekusaanira buli kika kya kookolo.
- Oncotype DX: Kino kye kigezo ekisinga okukozesebwa. Etunuulira obuzaale 21 mu sampuli entono eya kookolo wo. Okusinziira ku ngeri obuzaale obwo gye bukolamu obulungi, ofuna ‘obubonero bw’okuddamu okukola’ wakati wa 0 ne 100. Obubonero buno busobola okuyamba omusawo wo okutegeera engeri kookolo wo gy’ayinza okuddamu mu biseera eby’omu maaso n’okumanya oba ojja kuganyulwa mu bujjanjabi bw’eddagala. Wabula okukebera kuno kuyinza okukolebwa ku kookolo zokka alina estrogen-receptor positive era nga tesaasaana mu nnywanto.
- Ebigezo ebirala: Waliwo n'ebigezo ebiyitibwa `(MammaPrint)`, `(Breast Cancer Index)`, `(Pam50)`, ne `(EndoPredict)`. Ebimu ku bino biyamba okulagula obulabe bwa kookolo okuddamu oluvannyuma lw’emyaka etaano.
Okukebera omusaayi mu biseera eby’omu maaso
Mu kiseera kino ekibinja ky’abanoonyereza kigezaako okukola eky’okukebera omusaayi ekiyinza okuzuula oba kookolo ayolekedde okuddamu.
Okukebera okw’ekika kino kikulu nnyo ng’obujjanjabi bwonna buwedde, nga tewakyali bitundu bya kookolo ebisigadde okwekebejjebwa.
"Bwe tuba tusobola okumanya ddala ani agenda okuddamu okufuna kookolo, tusobola okusalawo oba beetaaga obujjanjabi obw'enjawulo. Olwo tusobola okutandika okunoonyereza ku bujjanjabi obupya obubakolera amangu," omu ku bannassaayansi abeenyigira mu kunoonyereza kuno bw'agamba. "Ekigendererwa kyaffe ekisembayo kwe kutangira kookolo w'amabeere agenda okusaasaana, nga muzibu okuddukanya era nga y'akola ebitundu 90% ku bantu abafa kookolo w'amabeere."
Wabula kigambibwa nti kijja kutwala emyaka emirala egiwerako okukola eky’okukebera omusaayi ekiyinza okukozesebwa abasawo .
Kiki ky’oyinza okukola?
Okutuusa nga bannassaayansi bafunye ebigezo ebipya nga bino, waliwo ebintu by’osobola okukola. Emize gyo egya bulijjo giyinza okuyamba okukendeeza ku bulabe buno. Ng’ekyokulabirako, kikulu okukola dduyiro buli kiseera n’okukuuma omugejjo omulungi .
Ekirala eky'okujjukira nti akabi k'okuddamu okulwala n'emiwendo gy'okuwona ebintu bibiri eby'enjawulo . Kino kikulu nnyo. Teebereza omuntu alina kookolo w’amabeere, n’afuna obujjanjabi, oluvannyuma kookolo n’akomawo oluvannyuma lw’emyaka ebiri. Naye singa kizuulibwa nga bukyali, omuntu oyo asobola okubeera obulungi okumala emyaka mingi.
Kale, tosubwa ssaawa yonna ey’okugoberera . Bw’oba olina ekibuuzo kyonna oba ekikweraliikiriza, kakasa nti obuuza omusawo wo.
"Kikulu okwogera n'omusawo wo n'otegeera bulungi akabi kwo ku bubwe kye kali ne kye kitegeeza. Kino kijja kukuyamba okusalawo obulungi ku bujjanjabi bwo. Okukola ku kookolo kiyinza okuba ekintu ekitiisa, ekitabula. Kale olina okuwulira nga weeyagaza okwogera n'omusawo wo ku by'otya."
Obubaka Obutwala Awaka
- Ebiseera ebisinga kookolo w’amabeere taddamu oluvannyuma lw’okujjanjabwa, n’olwekyo totya mu ngeri eteetaagisa.
- Obulabe bwa kookolo okuddamu businziira ku bintu nga obunene bw’ekizimba, okusaasaana mu bitundu ebiriraanyewo, n’ekika kya kookolo ow’ebiramu.
- Okumanya obulungi akabi k’olina n’okulonda obujjanjabi obusinga obulungi, abasawo basobola okukozesa okukebera okw’enjawulo nga Oncotype DX.
- Osobola n’okuyamba okukendeeza ku bulabe buno ng’okola dduyiro buli kiseera n’okukuuma obuzito bw’omubiri obulungi.
- Ekisinga obukulu kwe kwogera mu lwatu n’omusawo wo. Wuliriza byonna by'otya n'ebibuuzo byo. Era kikulu nnyo eri obulamu bwo obw'omutwe.
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