Wali owuliddeko ng’okooye, ng’okooye oba nga tolina ssanyu? Oboolyawo obuzito bwo bweyongedde oba bukendedde mu ngeri etategeerekeka, oba ofunye enkyukakyuka endala ezitali za bulijjo. Bino byonna biyinza okuba nga biva ku ‘master gland’ entono, naye nga ya maanyi nnyo mu bwongo bwo. Ekyo kye twogerako leero. Embeera eno mu by'obujjanjabi emanyiddwa nga hypopituitarism .
Ensigo y’omubiri (pituitary gland) ne hypopituitarism kye ki?
Mu ngeri ennyangu, endwadde ya pituitary gland nnywanto eringa entangawuuzi esangibwa wansi w’obwongo bwaffe, emabega w’ennyindo yaffe. Wadde nga ntono, ekola nga ‘master gland’ y’enkola y’obusimu mu mubiri gwaffe. Y'eyo egamba endwadde z'ekibumba, endwadde z'ekibumba, n'endwadde endala nnyingi nti, "Okay, kati okola obusimu buno."
Hypopituitarism (hypopituitarism) bwe buva ku nseke y’omubiri (pituitary gland), master regulator, obutakola busimu bumu oba okusingawo obumala. Oluusi, obusimu bwonna obukolebwa enseke z’omubiri (pituitary gland) busobola okukendeera. Kino tukiyita Panhypopituitarism . Embeera eno esobola okukwata abaana nga kw’otadde n’abantu abakulu. Era kiyinza okuva ku bulwadde bwa hypothalamus, ekitundu ky’obwongo ekifuga obubonero obujja mu nseke.
Obusimu buno bufuga emirimu emikulu mu mubiri gwaffe, gamba ng’okukula, okuzaala, puleesa, n’enkyukakyuka mu mubiri . Kale singa ekimu ku bino kiba kibulamu, enkola z’omubiri ezikwatagana nazo zisobola okutaataaganyizibwa.
Busimu ki obukulu obukolebwa enseke z’omubiri (pituitary gland) ze ziruwa?
Ensigo ya pituitary ekola ebika by’obusimu ebiwerako. Katutunuulire ebikulu ne bye bikola. Kijja kuba kikulu nnyo gy’oli okumanya kino.
| Obusimu obuyitibwa hormone | Enkola mu Mubiri |
|---|---|
| Obusimu obuyitibwa adrenocorticotropic hormone (ACTH) . | Kisitula endwadde z’ekibumba (endwadde ezisangibwa waggulu w’ensigo) era kiyamba okukola obusimu obuyitibwa cortisol obufuga puleesa n’enkyukakyuka mu mubiri. |
| Obusimu obuyamba okuzimba omubiri (TSH) . | Asitula endwadde z’ekibumba mu bulago n’ayamba okukola obusimu bwa thyroid, obwetaagisa ennyo mu kukyusakyusa omubiri, okukula n’okukula. |
| Obusimu obusitula enseke (FSH) ne Luteinizing hormone (LH) . | Bino bifuga enkola y’okwegatta n’okuzaala mu bakyala n’abasajja, ekiraga nti estrogen okuva mu nkwaso mu bakyala ate testosterone okuva mu nsigo mu basajja. |
| Obusimu obuyamba okukula (GH) . | Nga erinnya bwe liraga, kyetaagisa nnyo mu nkula y’amagumba n’ebitundu by’omubiri ebya bulijjo naddala mu buto. |
| Ekirungo kya Prolactin | Kisitula enkula y’amabeere mu bakyala n’okukola amata okusobola okuyonsa. |
| Obusimu obuziyiza okufulumya omusulo (ADH) . | Ensigo zifuga okufulumya amazzi mu mubiri. Singa kino kikendeera, omusulo oguyitiridde guyinza okubaawo. |
| Ekirungo kya oxygen | Ayamba nnabaana okukonziba ng’ozaala n’okuyamba amata okutambula ng’oyonsa. Obusimu buno era bukulu nnyo mu nkolagana wakati wa maama n’omwana. |
Biki ebivaako obulwadde bwa hypopituitarism?
Embeera eno eva ku kwonooneka kw’endwadde ya pituitary gland oba hypothalamus. Oluusi ekivaako kiyinza obutazuulibwa. Bino bye bimu ku bikulu ebivaako ensonga eno:
- Ebizimba mu nseke oba okwetooloola endwadde z’omu lubuto
- Obujjanjabi bw’amasannyalaze (radiation therapy) ku kookolo
- Okulongoosa obwongo oba ku nseke y’omubiri (pituitary gland).
- Yinfekisoni nga obulwadde bwa meningitis
- Ebisago eby’amaanyi ku mutwe
- Okusannyalala oba okuvaamu omusaayi mu bwongo
- Eddagala erimu
- Okuzimba okuva ku buzibu mu baserikale b’omubiri
- Okuvaamu omusaayi omungi ng’ozaala (Sheehan’s syndrome) .
- Ebimu ku bivaako obuzaale ( genetic mutation ) .
- Embeera endala ez’obujjanjabi nga sarcoidosis n’akafuba
Obubonero buno buli butya?
Obubonero businziira ku busimu ki obubulamu n’engeri embeera eno gy’ekula amangu . Abantu abamu bayinza obutaba na bubonero bwonna, oba obubonero buyinza okukula mpola nnyo. Abalala bayinza okufuna obubonero obw’amaanyi mu bwangu.
Laba ekipande wansi ku bubonero obukwatagana ne buli bbula ly’obusimu.
| Obutaba na Busimu | Obubonero Obuyinza Okubaawo |
|---|---|
| Obutabeera na ACTH | Okukoowa ennyo, okukoowa, puleesa okukka, okugejja, okuziyira, okusesema, okwennyamira. |
| Obutabeera na TSH | Okuziyira, okugejja, obutasobola kugumira nnyonta, okufiirwa amaanyi, okulumwa ebinywa oba okunafuwa. |
| Obutabeera na FSH ne LH | Ku bakyala: obutagenda mu nsonga oba okulekera awo, okukaluubirirwa okuzaala (obutazaala). Ku basajja: okuggwaamu enviiri mu maaso n’omubiri, okunafuwa, obutayagala kwegatta, obutaba na busajja, okukaluubirirwa okufuna embuto. |
| Obutabeera na GH | Ku baana: okukula okutambula obulungi, amasavu okukuŋŋaanyizibwa mu kiwato ne mu maaso, n’okutwalira awamu okukula obubi. Ku bantu abakulu: okukendeera kw’amaanyi, okukaluubirirwa okukola dduyiro, okweyongera okugejja, okukendeera kw’ebinywa, okweraliikirira oba okwennyamira. |
| Obutabeera na ddagala lya prolactin | Ku bakyala: Okulemererwa okukola amata g’amabeere nga bamaze okuzaala. |
| Obutabeera na ADH | Ennyonta eyitiridde n’okufuka ennyo, okufuka ennyo (Diabetes Insipidus). |
| Obutabeera na oxytocin | Ku bakyala: obuzibu n’amata letdown. |
Bw’oba olina obubonero buno bumu oba obusingawo, nsaba tobubuusa maaso. Kakasa nti olaba omusawo wo n’okyogerako.
Kino okisanga otya Omusawo?
Bw’olaba omusawo, ajja kuwuliriza n’obwegendereza obubonero bwo era akusindikire okukeberebwa okwetaagisa.
- Okukebera Omusaayi: Kino kye kisinga obukulu. Zipima obusimu obw’enjawulo mu musaayi gwo. Oluusi, obusimu buweebwa oluvannyuma ne bakola okukeberebwa okw’enjawulo (okukebera okusikirizibwa oba okunyigiriza) okutunuulira enkyukakyuka mu musaayi mu ssaawa ntono. Eby’okulabirako: `ACTH (Cortrosyn) okugezesebwa okusikirizibwa`, `GH okugezesebwa okusikirizibwa`.
- Okukuba ebifaananyi: MRI oba CT scan eyinza okukolebwa okukebera oba waliwo ekizimba mu pituitary.
- Okukebera okulaba: Okuva obusimu obukwatagana n’amaaso bwe buyita okumpi n’endwadde z’omu lubuto (pituitary gland), okulaba kukeberebwa okulaba oba ekintu ng’ekizimba kinyigiriza obusimu obwo.
- X-ray z’abaana: X-ray y’emikono gy’abaana ekolebwa okukebera oba amagumba gakula mu ngeri eya bulijjo.
Kijjanjabwa kitya?
Waliwo ebigendererwa bibiri ebikulu mu kujjanjaba embeera eno. Ekimu kwe ku...Okujjanjaba ekizibu ekivaako (okugeza, okuggyawo ekizimba). Ekintu ekyokubiri era ekisinga obukulu kwe kukyusa obusimu obubula mu mubiri . Kino kiyitibwa Hormone Replacement Therapy .
Eddagala
Omusawo ajja kukuwa eddagala erituufu okusinziira ku busimu bw’obulamu.
- Ku bbula lya ACTH: Glucocorticoids (e.g. hydrocortisone) ziweebwa okutereeza emiwendo gya cortisol.
- Ku bbula lya TSH: Eddagala nga `Levothyroxine` liweebwa okutereeza obusimu bwa thyroid.
- Ku bbula ly’obusimu bw’okwegatta: Testosterone eweebwa abasajja ate estrogen (eyinza okuba nga erina progesterone) eri abakyala.
- Ku bbula lya GH: Empiso za Growth Hormone (GH) ziweebwa okuyamba mu kukula naddala mu baana. Abantu abakulu nabo oluusi baweebwa obujjanjabi buno okuyamba ku maanyi n’okukula kw’ebinywa.
- Ku butazaala: Waliwo obujjanjabi obw’enjawulo obw’obusimu nga Gonadotropin okusitula okukula kw’amagi oba okukola ensigo.
Okuloongoosa
Singa ekizimba kye kivaako embeera eno, kiyinza okwetaagisa okulongoosebwa okukiggyamu okusinziira ku kika n’ekifo ekizimba we kiri.
Kiki kye tusaanidde okulowooza ku biseera eby’omu maaso? (Endowooza)
Amawulire amalungi gali nti singa obulwadde buzuulibwa bulungi era n’eddagala erikyusa obusimu ne liweebwa mu butuufu, kisoboka okubeera n’obulamu obulungi ennyo era obulungi . Obujjanjabi buyinza okuba obw’obulamu bwonna.
Ekisinga obukulu kwe kugoberera omusawo wo mu budde . Olw’okuba obwetaavu bw’obusimu bw’omubiri gwo buyinza okukyuka okumala ekiseera, kikulu okubeera ng’okwatagana n’omusawo buli kiseera.
Obubaka Obutwala Awaka
- Hypopituitarism bwe buva ku nseke, ‘master gland’ y’omubiri gwaffe, obutakola busimu bwetaagisa bumala.
- Obubonero bwawukana okusinziira ku muntu okusinziira ku busimu ki obubulamu. Obubonero buyinza okuli okukoowa, okugejja, n’obutakola bulungi mu kwegatta.
- Bw’oba olina obubonero nga buno obutategeerekeka, laba omusawo mu bwangu .
- Embeera eno esobola okuzuulibwa obulungi ng’oyita mu kukeberebwa omusaayi ne sikaani.
- Obujjanjabi buno kwe kuwa obusimu obubula ebweru. Obujjanjabi buno bukola nnyo.
- Bw’omala okutandika obujjanjabi, sisinkana omusawo mu kiseera ky’otegese.Okutereeza dose kikulu nnyo.
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