Kan chhungkuaa mi tu emaw, kan nu, kan pa, kan pi, kan pi leh pute duh tak te pawh a ni mai thei, kum upat deuh deuhin thil an theihnghilh zauh zauh thin kan hmuh hian tlemin kan hlauthawng a, kan lungngai deuh thin a ni lawm ni? "Hei hi Alzheimer natna bul tanna a ni em?" Hei hi mi tam takin zawhna an neih a ni. Chuvangin vawiin hian Alzheimer natna chungchang hi awlsam tak leh ngilnei takin i sawi ang u, a nghawngtu thil hmuhchhuah tharte chungchang te, a pawimawh ber chu he natna laka kan invenna atana kan tih theih turte chungchang te hi han sawi ila.
Alzheimer natna hi eng nge ni tak tak?
A awlsam zawngin sawi ila, Alzheimer’s hi zan khata natna a ni lo. Zawi zawiin, kum tam tak chhung, kan thluak chhungah a lo awm thin. A chang chuan thluaka inthlak danglamna hi kum 10 atang pawhin a intan thei a, chu chu symptoms i hriat tan hma pawh a ni thei.
Scientist-te sawi dan chuan a chhan ber chu thluak cell inkara protein chi hnih a ṭul lo taka a khawlkhawm vang a ni.
1. Beta-amyloid plaques: Hengte hi thluak cell inkara protein ‘clot’ awm khawm ang a ni.
2. Tau tangles: Hengte hi thluak cell chhunga protein ‘tangles’ siam a ni.
Hetiang hian han ngaihtuah teh: kan thluak cell te hi inbiak leh thu inhrilh tawn ngai mi ang an ni. Heng protein clump leh tangles te hian chu cell te chu an inbiakpawhna tur a veng a ni. Hun a kal zel a, heng thluak cell te hi an thi zauh zauh a. Chutah chuan kan ngaihtuahna, hriatrengna leh ngaihtuahna thiamna a tlahniam ta a ni.
Hei hi eng risk factors nge a nghawng?
Alzheimer natna lo awm chhan hi thil engemaw zat a awm a. Chung zinga ṭhenkhat chu kan thunun thei a, ṭhenkhat chu kan thunun thei lo.
A pawimawh ber chu i chhungkaw doctor nen inbiakna neihpui la, heng risk factors te hi i nei tih i hriat chuan thurawn la rawh.
| Risk factor a ni | Hrilhfiahna awlsam tak |
|---|---|
| Kum upa lam | Kum 65 hnuah pawh a hlauhawmna a sang chho zel a, mahse hei hi tar chakna pangngai a ni lo. |
| Chhungkaw chanchin (Genetics) . | I chhungkuaa mi (nu, pa, unau) hian he natna hi an vei tawh a nih chuan nang pawh hi tlem chuan i hlauhawmna a sang zawk a ni. |
| Thisen sang a sang | Thisen sang thunun loh chuan thluak a tichhe thei a ni. |
| Cholesterol sang tak a ni | Hei hian thisen kaltlangin thluak a nghawng bawk. |
| Zunthlum | Zunthlum control loh hian Alzheimer’s vei theihna nasa takin a tipung a ni. |
| Meizial zuk | Cigarette-a toxin awmte hian thluak hriselna atan direct-in a tichhe thei a ni. |
| Thau lutuk | Taksa rih lutuk avanga taksa inthlak danglamna hian thluak a nghawng bawk. |
Tunah chuan scientist-te chuan Alzheimer natna hi heng risk factor tam tak ang bawkin kan taksa chhunga thil dang pahnih: oxidative stress leh chronic inflammation te hian a nghawng bawk niin an sawi.
Oxidative Stress tih hi eng nge ni?
He hming i hriat hian hlau suh. A awlsam khawp mai.
Kan taksa cell-te hian free radicals tih hming pu thil hlauhawm tak tak an siam chhuak fo thin. Tin, pawn lam thil, meizuk leh boruak bawlhhlawh a\angin taksaah an lut bawk.
Mahse, kan taksa hian heng thil tha lo tak takte tichhe thei "sipai" tha tak tak a nei bawk. Antioxidants kan ti thin .
Oxidative stress chu free radicals tamnain antioxidants a tam zawk a nih chuan a ni. Scale chu a sir khatah tip ang mai a ni. He inthlauhna hian kan cell te a tichhia a, tar chakna a ti chak bawk. Hei hian natna tam tak kawng a hawng a, Alzheimer’s chauh ni lovin, Parkinson’s, cancer, leh heart disease te pawh a hawng a ni.
Mak tak maiin Alzheimer’s thlentu protein beta-amyloid an tih hian antioxidant angin hna a thawk bawk. Mahse oxidative stress a san chuan chu protein vek copy dik lo, chhiatna thlen thei chu a lo awm tan ta a ni. Chu chu thluaka a pungkhawm a, harsatna a thlen thin chu a ni.
Engtin nge inflammation hian taksa a nghawng?
Inflammation hi a takah chuan kan taksaa invenna a ni. I kut i tan a, a sen a, a hring a, a lum a nih chuan han ngaihtuah teh, a dik em? Chu chu inflammation a ni. Taksain natna hrik dona leh hliam tihdamna atana a tih thin a ni.
Mahse, he inflammation hi a chhunzawm zel a nih chuan, chu chu chronic inflammation a lo ni ta a nih chuan, in chhunga security guard pakhatin in a tibuai reng a, in chhung ngei pawh a tichhia reng ang mai a ni.
Hei hi Alzheimer natnaah chuan a thleng thin. Hetiang thluaka inflammation rei tak hian a hmaa kan sawi tawh beta-amyloid plaques leh tau tangles te chu a ti na zual sauh sauh a ni. Hei hian thluak cell a tihchhiatna a tipung a ni.
Chûng dinhmunte thunun tûrin eng nge kan tih theih?
Thu lawmawm tak chu nunphung thlak danglamin oxidative stress leh chronic inflammation te hi kan control thei a, chu chu Alzheimer’s vei theihna tihziaawmna turin kan kut ngeiah thiltihtheihna tam tak kan nei tihna a ni.
| Eng nge tih tur | Engvangin nge tih leh engtin nge tih ang? |
|---|---|
| Meizial zuk loh tur. | Cigarette hi free radicals dahkhawmna hmun a ni. Meizial zuk bânsan hian Alzheimer’s vei theihna chu direct-in a tihziaawm thei a ni. |
| Zu hi tihtlem rawh. | Zu in nasa hian thluak a tar chak zawk. Moderate drinking tih hi hmeichhia tan ni khatah vawi khat in tur (e.g., beer can khat) leh mipa tan pahnih in tur tihna a ni. |
| Ei leh in hrisel | Thei, thlai (a bik takin leafy greens), leh antioxidant tamna ei tur (vitamins C leh E) ei thin ang che. Nga hriak nei, salmon leh olive oil te hian inflammation a ti tlem. Fried leh processed foods ei loh tur. |
| Probiotics te hi enchhin rawh. | Kan gut chhunga bacteria tha tak tak te hi thluak hriselna atan pawh a pawimawh hle. I eitur ah hian yogurt leh bawnghnute ang chi te telh bawk ang che. |
| Insawizawi. | Kar khatah ni 3-5 chhung minute 20-30 chhung exercise la. Brisk walking emaw gardening emaw pawh hi exercise tha tak a ni. I thawkrim lutuk suh, hei hian free radicals siamchhuahna a tipung thei a ni. |
| I taksa rihna hrisel tak vawng reng rawh. | Thau lutuk hian taksa pum puiah inflammation a thlen thin. Thluak a nghawng bawk. |
| Stress tihziaawm rawh. | Stress hi inflammation leh oxidative stress thlentu lian tak a ni. Yoga, meditation, leh deep breathing exercise ang chi thilte hian a pui thei a ni. |
| Mut tawk rawh. | Kan mut lai hian thluak hian chutiang beta-amyloid plaques duh loh chu a tifai vek a ni. Nitin zan mut that hi a pawimawh hle. |
Take-Home Thuchah a ni
- Alzheimer’s hi kan tar chhoh zel a thil theihnghilh mai mai a ni lo va, thluaka thil thleng danglam bik (complex changes) avanga lo awm a ni.
- He natna hi rinhlelh ber pahnih oxidative stress leh chronic inflammation te an ni.
- I nunphung hi i humhimtu tha ber a ni. Ei leh in hrisel ei te, exercise lak te, zu in loh te, stress control te, leh mut tam te hmangin i hlauhawmna chu nasa takin i tihtlem thei a ni.
- Nangmah emaw, i hmangaih tak emaw chuan hriatrengna lama harsatna i neih chuan, khawngaihin i doctor biak chu hlau lo la, zak suh . Thurawn lak hmasak a pawimawh hle.
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