AA Amyloidosis hi eng nge ni? A chanchin awlsam takin i zir ang u!

Kan taksaa protein thenkhat chu tlem a lo haywire ta se eng nge thleng thei ang tih i ngaihtuah ngai em? Vawiin hian chutiang dinhmun tlemte, mahse hriat tur pawimawh tak pakhat kan sawi dawn a ni. A hming chu AA Amyloidosis a ni.

AA Amyloidosis hi eng nge ni? A awlsam zawngin i hrethiam ang u!

A awlsam zawngin sawi ila, AA Amyloidosis hi natna chi khat, amyloidosis an tih hi a ni. Tunah chuan, ‘He amyloidosis hi eng nge ni?’ tiin i zawt mai thei. Awle, kan taksa hian protein chi khat amyloid an ti a. Heng protein te hian a bik takin three-dimensional shape (3D structure) an nei a. Chutiang chuan hna an thawk a ni. Mahse, a chang chuan heng protein te hi an pianzia an thlak a, thread ball ang maiin an inzawm khawm a, fiber te te (fibrils) an siam thin. Hei hi ‘amyloid deposits’ kan tih chu a ni. Kan taksa peng hrang hrang leh kan taksa peng hrang hranga heng deposit awmkhawmte hi amyloidosis an ti a.

AA amyloidosis-ah chuan kan taksaa inflammation tam lutuk vangin thisenah serum A protein level a sang hle. Hun rei tak infection emaw inflammatory disease emaw i neih chuan he serum A protein level hi a sang thei a ni. Kawng khatah chuan AA amyloidosis hi heng inflammatory diseases te hi a complication na tak a ni. Doctor-te chuan a hnuaia inflammatory disease awm chu enkawlin an enkawl thin.

Engtin nge AA amyloidosis hian kan taksa a nghawng?

Tunah chuan he AA amyloidosis hian kan taksa a nghawng dan hi han en ila. Kan kal (kidney) a tichhe nasa ber . Chu mai ni lovin, thin, ril, pum, leh intestines te pawh a tichhe thei a ni. Thinlung a nghawng tlem hle. Thil dang chu he natna hian i zun a protein awm zat leh i thisena cholesterol level a nghawng thei a ni.

Hei hi thihna thlen thei dinhmun a ni em?

Ni e, hei hi harsatna lian tak a ni tak zet a ni. AA Amyloidosis hi enkawl tha a nih loh chuan thihna thlen thei a ni . Hei hi hun rei tak chhunga natna hrik thlentu natna avanga lo awm a ni tih ka sawi kha hre reng ang che. Chuvangin, doctor-te’n natna hnuaia awm an enkawl hian AA amyloidosis pawh an enkawl bawk. Chuvangin ngaihtuahawm tur a awm lo va, mahse a pawimawh ber chu hriat hmasak a, enkawlna lak hi a ni .

Tute nge AA amyloidosis vei tam ber?

Hetiang hi tuin nge vei thei tih i ngaihtuah chuan, chronic inflammatory condition nei apiang chu AA amyloidosis vei theihna a ni . Chumi awmzia chu, chutiang natna i neih chuan hei pawh hi tlem tal hriat chian a tha.

Eng thilin nge AA amyloidosis hi a thlen?

Hei hi eng thil nge a thlen tih hi ngun zawkin han thlir ila. AA amyloidosis hi amyloidosis chi khat a ni. Doctor-te chuan he amyloidosis hi ``protein misfolding disorder'' an ti a, han ngaihtuah teh, kan protein te hi molecule sei tak tak, special three-dimensional (3D) shape nei an ni. Heng protein te hian kan taksaah hna tam tak an thawk a – chakna pek atanga tui inthlauhna thlengin, immunity a puih thlengin, taksa insiam dan pek thlengin, thil a kal kual a, taksa kalphung control thlengin, leh a dangte.

A tlangpuiin heng protein te hi an hna an thawh zawh chuan thisen atangin an paih chhuak thin. Mahse, heng protein te hi a fold dik lohna disorder-ah chuan protein te hian an pianzia an thlak a, taksain a hman theih loh leh a paih theih loh pianphung pangngai lo tak tak an nei ta a ni. AA amyloidosis-ah chuan heng protein pangngai lote hi an inzawm khawm a, kan taksa peng hrang hrangah ‘amyloid deposits’, a nih loh leh `fibrils’ an siam thin.

Tun hnaia zirchianna hrang hrangah AA amyloidosis thlen thei dinhmun engemaw zat hmuhchhuah a ni. Chung zingah chuan thisen cancer chi hrang hrang, bacteria infection, chronic ulcers, rheumatic diseases, rheumatoid arthritis, emaw inflammatory bowel diseases, Crohn’s disease emaw ulcerative colitis emaw te pawh a tel. A châng chuan, pianphung aṭanga lo chhuak, periodic fever syndromes, familial Mediterranean fever ang chi te pawh a awm thei bawk.

AA amyloidosis natna lan chhuah dan chu engte nge ni?

Okay, tunah chuan AA amyloidosis symptoms te chu eng nge ni tih kan en ang. A tam zawkah chuan kal (kidney) a nghawng thin. Tin, taksa peng hrang hrang liver, spleen, leh stomach te pawh a nghawng thei bawk. Heng symptoms te hi i nei em tih en rawh:

• Ke emaw ke ruh emaw a hring chhuak . Hei hi kal lama harsatna nei chhinchhiahna a ni thei. Chronic kidney disease chhinchhiahna a ni thei bawk.
• Foamy emaw frothy emaw zun a awm.
• A tlangpui aia zun chhuah tlem zawk.
• Chronic diarrhea a awm thin.
• Kidney a lian thei hle.
• Liver a lian thei hle.
• Thisen sang hniam.
• Nausea leh luak chhuak.

Doctor-te hian engtin nge AA amyloidosis hi an hriat theih?

He natna hi Doctor ten engtin nge an hriat chian? Test hrang hrang an nei thin. A bulpui ber chu biopsy a ni.

• ``Fat pad'' biopsy : Hei hi pum chhunga vun hnuai atanga thau tlemte lak a, enfiah a ni. A awlsam khawp mai.
• Organ biopsy : Organ a nghawng nia ngaih atanga tissue sample te tak te lak a, enfiah a ni.

Chu bakah, test dang pawh tih theih a ni a, amyloidosis chi dang ``AL amyloidosis'' an tih chu i nei em tih finfiah theih a ni.AL amyloidosis leh AA amyloidosis pahnih symptoms hi a inang em em a, AL amyloidosis hi a na zawk leh a zual chak zawk chi a ni

AA amyloidosis hi engtin nge enkawl a nih?

Tunah chuan hei hi eng treatment nge tih i en ang u. AA amyloidosis hi hun rei tak chhunga inflammatory condition avanga lo awm a ni a, chu chuan i taksa peng hrang hrangah protein pangngai lo a siam chhuak thin. Chuvangin, doctor-te chuan a hnuaia inflammatory condition enkawlin an enkawl a ni . A hnuaia awm chu i enkawl a, inflammation i tihtlem chuan AA amyloidosis condition pawh a control thei bawk. Inflammation level a tlahniam chuan symptoms te chu a tlahniam zauh zauh thin.

Tunah hian AA amyloidosis enkawlna atana damdawi hman theih a awm bawk. Doctor leh zirchiangtute chuan enkawlna thar an dap chhunzawm zel a. Entirnan, heng amyloid fibrils te hi taksa peng hrang hranga an lo awm hmaa thisen atanga lakchhuah dan tur an zirchiang mek a, lab-a siam antibodies te pawh an zirchiang mek a, chu chuan taksa peng hrang hranga amyloid fibrils lo awm tawhte chu target leh paih chhuak thei a ni.

AA amyloidosis hi ven theih a ni em?

Hei hi ven theih a ni em? Dik tak chuan rheumatoid arthritis ang chi chronic inflammatory disease i neih chuan thisenah protein thenkhat a tipung thei a, AA amyloidosis a thlen thei bawk. Chuvangin, chutiang laka inven theihna awmchhun chu i neih underlying chronic inflammatory disease chu rang tak leh dik taka enkawl hi a ni .

AA amyloidosis hi tihdam theih a ni em?

Ni e, tihdam theih a ni. Doctor-te chuan AA amyloidosis hi a thlentu inflammatory condition hnuaia awm chu an enkawl a ni. Natna tam tak ang bawkin AA amyloidosis enkawl dan tha ber chu natna hi hriatchhuah a, a rang thei ang bera enkawl tan hi a ni .

Engtin nge ka in enkawl ang?

AA amyloidosis i vei a nih chuan i in enkawl dan tha ber chu i doctor nen thawk hovin a thlentu underlying inflammatory condition chu uluk taka enkawl hi a ni. Researcher te chuan hun rei tak chhunga inflammation thlen thei natna leh dinhmun hrang hrang AA amyloidosis nena inzawm an hmuchhuak a. I doctor hnenah engtin nge i natna hian AA amyloidosis a thlen tih leh chu inflammatory condition chu engtin nge an enkawl tih zawt rawh.

A awlsam zawngin sawi ila, AA amyloidosis hi inflammatory disease emaw condition tlanglawn tam tak avanga harsatna awm lo, mahse pawi tak a ni. Vanneihthlak takin doctor-te chuan a hnuaia natna awm chu enkawlin an enkawl thei a ni. Vawi tam tak chu AA amyloidosis symptoms hi i inflammatory disease-a i harsatna tawh thin ang kha a ni thei. Mahse, natna khirh tak dang ang bawkin doctor-te chuan a hmaa an man chuan an enkawl tam zawk.I arthritis-ah hian danglamna emaw, chhinchhiahna thar emaw i hmuh chuan i doctor hnenah hrilh nghal rawh . I symptoms te an enfiah ang a, a awmzia an sawifiah ang.

Chuti a nih chuan, he thawnthu atang hian eng thil nge kan hriat reng tur pawimawh ber?

AA Amyloidosis hi thumal hlauhawm deuh a ni a, mahse hriatthiamna dik tak neih a pawimawh hle.

Hei hi hun rei tak chhunga inflammatory disease dang complication angin a thleng fo tih hre reng ang che.

• Natna hlauhawm tak, rheumatoid arthritis ang chi i neih chuan damdawi lam enkawlna dik zawn a pawimawh hle .
• I natna lan chhuahna thar, kal lama harsatna (ke-a hring, zun inthlak), ril\am chhunzawm zel, emaw, thin emaw, ril emaw a lian emaw ang chi i neih chuan i doctor hnenah hrilh rawh
• AA amyloidosis hi hriatchhuah leh enkawl hmasak a nih chuan result tha tak a awm thei . Enkawlna bulpui ber chu a hnuaia inflammatory disease enkawl hi a ni.
• Hlau suh, mahse fimkhur rawh . I doctor nen zalen takin inbia la, i harsatnate hrilh rawh. An pui ang che.

Chuvangin, he thu hi i tan a tangkai ngei kan beisei. Hrisel takin awm rawh!

` Amyloidosis, AA amyloidosis, protein, inflammation, kal natna, natna rei tak, rheumatoid arthritis