I thisen chu awlsam takin a inzawm em? Antithrombin Deficiency chungchang hi i zir dawn teh ang!

Kan taksaah hliam tenau tak awm mah se, thisen chhuah chu rei vak lo hnuah a reh a, thisen a zam a, a dik em? Kan taksain a invenna mechanism mak tak a ni tak zet a ni. Mahse, he thisen zam hi a tul aia nasain a pung a nih chuan, a nih loh leh chhan awm lova taksa chhungah thisen zam a lo awm a nih chuan? Tichuan buaina a ni thei. Vawiin hian a tul lova thisen zam chhan bik kan sawi dawn a ni. Chu chu Antithrombin Deficiency , thenkhat chuan Antithrombin III Deficiency an ti bawk.

Antithrombin Deficiency hi eng nge ni tak tak?

A awlsam zawngin sawi ila, antithrombin tlakchhamna hi kan thisen zam (blotting process) nena inzawm a ni. Hetah hian kan taksaa thil pawimawh tak , thisen zam tam lutuk tur venna antithrombin an tih protein tlahniam emaw, a thawk tha lo emaw a ni thei.

Hetiang hian han ngaihtuah teh. Bathtub pakhat tuiin i khat a. Mi tu emaw chuan faucet chu a luang chhuak hmain a off a ngai a, chuti lo chuan tui zawng zawng a luang chhuak vek ang. Chutiang chuan, kan thisen a inzawm tan chuan, he thil antithrombin an tih hian a hun takah a "titawp" a, a thleng lutuk loh nan a veng a ni. Chuvangin, i taksaah antithrombin i neih tlem chuan, emaw, a thawk tha lo a nih chuan, thisen zam (blood clots) a awm reng thei a, chu chu bathtub a luang chhuak ang chi hi a ni. Hei vang hian thisen zam (abnormal blood clots) i neih theihna chance a sang zawk a ni .

Hetiang natna vei te hi a bik takin ke ruh thuk takah thisen zam (`Deep Vein Thrombosis` emaw `DVT`) leh thisen zam a inthen a, lung chhunga thisen zam (`Pulmonary Embolism` emaw `PE`) a awm theihna a hlauhawm hle. Hengte hi dinhmun hlauhawm tak tak a ni thei.

Hetiang dinhmun hi engtiang chiahin nge a awm?

Antithrombin Deficiency hi a takah chuan a awm lo hle a ni . Mi 2,000 atanga 3,000 zinga pakhat chauhvin an nei nia chhut a ni. Chu chu mi zawng zawng chungah a thleng lo tihna a ni lo.

Antithrombin tlakchhamna chhinchhiahna engte nge ni?

Hetiang natna vei zawng zawng hian symptom inang an nei vek dawn lo. Mi thenkhat chuan symptom engmah an nei lo mai thei. Mahse, a tam zawkah chuan thisen zam hmasa ber hi kum 40 an tlin hmain a thleng thin .

A lan chhuah dan hmuh tam ber chu:

• Deep Vein Thrombosis (DVT): Hei hian ke a ti na a, a sen a, a ti na a, khawih pawhin a lum thei bawk.
• Pulmonary Embolism (PE): Hei hian thawk hah thut, rilru na (a bik takin thawk laiin), thawk rang, khuh (a chang chuan thisen nen), leh thawk hah lohna a thlen thei. Hei hi emergency treatment ngai tak a ni.

Heng bakah hian, a tlem hle nachungin, thluak veins , emaw, abdominal veins-ah emawThisen zam a lo awm theihna a awm.

Engvangin nge he antithrombin tlakchhamna hi a lo awm?

A tam zawkah chuan he natna hi a chhan chu genetic , kan nu leh pate hnen atanga kan rochun thil a ni tihna a ni.

• Gene Mutation: Antithrombin Deficiency hi `SERPINC1` an tih gene-a mutation (change) nei te zingah a awm thin. He gene hian taksa chu antithrombin siam turin a hrilh a ni.
• Inheritance: He gene mutation hi nu leh pa tu emaw hnen atangin i inherit thei a ni. Chutiang a nih chuan 50% in i vei theihna chance i nei a ni. Hmeichhia emaw, mipa emaw pawh nise a pawi lo. Mahse, naute nu leh pa pahnih atanga he gene mutation rochun te hi an dam chhuak lo tlangpui. Hei hi a tlem hle.

A pawimawh ber chu he gene mutation nei zawng zawng hian thisen zam an nei vek lo. Mi thenkhat chuan an dam chhung zawng harsatna nei lovin an hmang thei a ni.

Doctor-te hian engtin nge hei hi an hriat?

Heng symptoms te hi i neih chuan, emaw, i chhungkuaa mi pakhatin hetiang natna hi a nei tih i hriat chuan doctor pan a, check out a tha. Doctor chuan a tlangpuiin hetiang hian a ti ang:

• Taksa enfiah: I taksa chu enfiah a ni ang.
• Medical history: I natna lan chhuah dan leh i chhungte zingah hetiang harsatna nei an awm leh awm loh zawh i ni ang.
• Thisen test: A pawimawh ber chu thisen a antithrombin level enfiahna tur thisen test bik neih hi a ni.

Heng test te hi he natna hi a awm leh awm loh finfiah theihna awmchhun a ni.

Treatment atan eng nge i tih?

Enkawlna chu thisen zam i neih leh neih lohah a innghat a ni.

• Thisen zam i neih chuan: I doctor chuan thisen tithianghlimtu hman tan tir che a tum mai thei . Hei hi a tam ber chu warfarin (Coumadin tia sawi i hre tawh mai thei). Hei hian thla engemaw zat a daih thei a, dam chhung zawng pawh a daih thei bawk.
• Thisen zam i nei ngai lo a nih chuan: Antithrombin tlakchhamna i nei a nih pawhin, thisen zam i nei ngai lo a nih chuan, a tlangpuiin thisen tithianghlimtu damdawi i ei chhunzawm a ngai lo. Mahse, a then phei chuan (entir nan, operation lian tak neih hmain) hun rei lote chhung pek theih a ni.
• Naupai lai: Hetiang natna vei naupai zinga 3% leh 50% inkar hian naupai laiin thisen zam an nei thei a, chuvangin doctor chuan chutih hun chhunga thisen zam a lo awm loh nan damdawi `Heparin` injection pek a tum mai thei.

Engtin nge ka in enkawl ang? (Enkawlna a dawn laiin)

Thisen tihthianghlimna damdawi Warfarin emaw Heparin emaw i ei a nih chuan i doctor-in a hrilh ang chiaha damdawi ei a pawimawh hle.Tin, doctor nena appointment i neih apiangah kal ngei ngei tur a ni.

He damdawi hian thisen chhuah theihna a keng tel avangin i doctor chuan a dose dik tak i dawng em tih a enfiah fo tur a ni. Thisen test ang chi `Prothrombin Time` (PT) test hmangin Warfarin dose dik leh dik loh enfiah a ni.

Hetianga damdawi hman zat dik taka control hian thisen zam hlauhawm tak tak a veng thei a, a tul lova thisen chhuah pawh a veng thei bawk.

Thisen zam hlauhawmna tihziaawm nan eng nge ka tih theih ang?

Antithrombin tlakchhamna i neih chuan thisen zam i neih theihna tur tihziaawmna tur thil engemaw zat a awm a:

• Naupai venna damdawi ei loh tur: a bik takin estrogen awmna damdawi ei loh tur. Hemi chungchang hi i doctor nen sawiho rawh.
• Hormone therapy pumpelh: Menopause hnua hormone therapies thenkhat ei hian a hlauhawmna a tipung thei bawk.
• Hmun khatah rei tak awm suh: A bik takin hmun hla tak tak i zin emaw, hmun khata rei tak hnathawh emaw a nih chuan darkar hnih danah tal tho la, tlem tal kal kual la, i ke kha ti nghing rawh.
• Meizial zu lo la, zuk leh hmuam hmang rawh: Meizial hian thisen kalna kawng a tichhe nasa hle a, thisen zam theihna a tipung nasa hle.
• I taksa rihna hrisel tak vawng reng rawh: Thau lutuk hi thisen zam chhan dang a ni.

Chu bakah, major trauma, surgery, naupai, nau neih, leh tar ang chi thilte pawhin thisen zam i neih theihna a tipung bawk. Surgery neih a ngai emaw, naute i beisei emaw a nih chuan i dinhmun hi doctor hnenah hrilh rawh. A mamawh chuan intravenous (IV) injection angin antithrombin concentrate bik a pe thei che a ni.

Hetiang dinhmun hi a lo thlen loh nan kawng a awm em?

Vanduaithlak takin, genetic condition a nih avangin inherited antithrombin deficiency ven theih a ni lo . Kan nu leh pate hnen atanga kan rochun genes te hi kan thlak danglam thei lo. Amaherawhchu, thisen zam kan neih theihna tur tihziaawmna tur thil kan tih theih a awm.

Antithrombin tlakchhamna i neih chuan eng nge beisei tur?

Hetiang natna vei mi pathum zinga pakhat vel chuan puitlin hunah thisen zam an nei ang.

• Surgery leh che thei lo: Operation i neih a, rei tak i che thei lo a nih chuan (e.g., khumah i awm reng a ngai a nih chuan), thisen zam (blood clots) i neih theihna a sang zawk.
• Kum upa lam: He hlauhawmna hi kum upat deuh deuh hian a pung ve deuh bawk.
• Naupai: Antithrombin tlakchhamna nei te hian naupai lai emaw, nau neih hnuah emaw thisen zam pangngai lo an nei thei a, chuvangin hei hi ngaihven bik tur a ni.

Hetiang dinhmun hi eng chen nge a daih ang?

Genetic condition a nih avangin i piang chhuak a ni. Nun chhung zawnga daih tur thil a ni. Chu chu a dam kim thei lo tihna a ni. Mahse, uluk taka enkawl a nih chuan harsatna tlem zawk nen i nung thei a ni.

Hetiang dinhmun hi eng nge a thlir ang?

I thlirna chu thisen zam i neih leh neih lohah a innghat a ni. Thisen tithianghlimtu damdawi ei hian thisen zam dang a lo awm loh nan a pui thei a ni. Amaherawhchu, i doctor-in a sawi ang chiah chiah, a dose dik tak leh a hun tur dik taka ei a pawimawh.

Eng thilah nge a bîk takin ka fimkhur ang?

Antithrombin tlakchhamna i neih chuan `DVT` (ke chhunga thisen zam) leh `PE` (lung chhunga thisen zam) te hriattirna chhinchhiahna te hriat a pawimawh a, chutiang chuan tanpuina i dawng thuai thei ang.

• DVT symptoms: ke pakhat (a tlangpuiin pakhat chauh) a hring, a na, a sen, leh khawih pawhin a lum.
• PE symptoms: Thâwk a harsat thut, rilru na (thâwk laia a na zual), thawk rang, thawk hah, khuh (a chang chuan thisen nen).

Thisen tithianghlimtu (e.g. Warfarin) i ei a nih chuan thisen chhuah theihna a awm avangin a hnuaia mite hi hre reng ang che:

• Hriamhrei hriam tak (knife, razor, etc.) hman hunah fimkhur hle ang che
• Hliam thlen thei infiamna (e.g. rugby, boxing) a theih ang anga pumpelh tur a ni. Chutiang a nih loh chuan invenna hmanrua dik tak ha rawh.
• Hliam awlsam tak atanga pawh thisen chhuak a tawp lo a nih chuan, emaw, chhan awm lovah hliam i neih chuan doctor hnenah hrilh rawh.

Engtikah nge Doctor ka hmuh ang?

DVT i vei nia i rinhlelh chuan Doctor pan nghal rawh. DVT hi enkawl vat a pawimawh a, kea thisen zam chu a chhuak thei a, lungah a kal thei a, PE a thlen thei a ni.

Warfarin ang damdawi i ei a nih chuan, i tlu a nih chuan, emaw, thisen chhuak danglam tak (e.g., hnar, hmui, emaw ek atanga) i neih chuan doctor hnenah hrilh nghal rawh.

Engtikah nge Emergency Treatment Unit (ETU) ah i kal a ngaih ?

Chutiang dinhmunah chuan damdawi in Emergency Treatment Unit (ETU) ah i kal nghal tur a ni :

• `Pulmonary Embolism (PE)` (thâwk harsa nghal, rilru na ang chi) symptom i neih chuan.
• DVT symptoms nei nia i inhriat a, mahse i doctor i biak theih loh chuan engtin nge ni ang?
• Thisen tina damdawi i ei a nih chuan, i lu i vuak a nih chuan, thisen i luak a nih chuan, emaw, hliam atanga thisen chhuak i chawlhsan thei lo a nih chuan.

Hengte hi nunna atana hlauhawm emergency a nih avangin tihkhawtlai suh.

Doctor ka zawh tur zawhna pawimawh te chu engte nge ni?

Hetiang natna hi i nei tih i hriat veleh i doctor hnenah hetiang zawhna hi i zawt thei ang:

• Warfarin emaw thisen tithianghlimtu dang emaw ka ei a ngai em? Eng chen nge ka lak a ngaih?
• Ka chhungte dang (nu leh pa, unau, fate) te Antithrombin Deficiency test tir hi a tha em?
• Hetiang dinhmun hi eng exercise nge him taka ka tih theih ang?
• Naupai hmaa ka hriat tur bik a awm em?

I dinhmun hriatthiamna tha zawk neih theih nan heng ang zawhnate hi zawt rawh.

A tawp berah chuan i hriat reng tur thil (Take-Home Message) .

Antithrombin Deficiency hi genetic condition a nih avangin kan thunun thei lo. Mahse, he dinhmun hi hriat chian a, a tul anga hma i lak chuan nun hrisel zawk i nei thei a ni.

A pawimawh ber chu nang leh i chhungte tan DVT leh PE vaukhânna chhinchhiahnate hriat chian a ngai a, chutiang chuan thil engemaw a kalsual a nih chuan i hre hmasa thei ang a, inenkawlna i zawng vat thei ang.

I rihna control te, active taka awm (exercise neih fo), leh meizuk loh te hian duh loh zawng thisen zam i neih theihna tur a ti tlem thei a ni. Chutiang chuan he dinhmun hian i nunah nghawng a neih chu eng emaw chen chu i thunun thei ang. Doctor nen inbia fo la, a thurawn chu uluk takin zawm rawh. Lungngai suh, nangmah chauh i ni lo!

` antithrombin tlakchhamna, thisen zam, DVT, pulmonary embolism, genetic diseases, thisen tithianghlimtu, warfarin, heparin