I thinlung dinglam chu a chak lo em ni? He ARVD (Arrhythmogenic Right Ventricular Dysplasia) hlauhawm tak hi i zir dawn teh ang?

Aw, a chang chuan i rilru a na nghal mai ang maiin i hria em, thawk harsatna i nei ang maiin i inhria em, a nih loh leh heart attack i nei ang maiin i inhria em? A châng chuan infiammi naupang, hrisel tak pawhin heart attack a nei nghal mai thei tih i hre tawh ngei ang. Chu chu vawiinah kan sawi dawn a, mahse a hriat lar lo deuh, thinlung natna tlem deuh a ni. Hei hi ``Arrhythmogenic Right Ventricular Dysplasia`` an ti a, a tawi zawngin ARVD an ti bawk.

ARVD (Arrhythmogenic Right Ventricular Dysplasia) tih hi eng nge ni? A awlsam zawngin i hrethiam ang u!

A awlsam zawngin sawi ila, ARVD hi heart muscle tichhe thei natna a ni a, `cardiomyopathy` chi khat a ni. Kan thinlung hian pindan pali a nei a. Hemi kawngah hian thil thleng chu i thinlung dinglam sir hnuai lam chamber-a muscle, `right ventricle` chu thau leh fibrous tissue aiah a lo thang lian zawk a ni. Muscle hrisel tak chu a tichhe vek a, thau ang chi thilin a thlak ang maiin ngaihtuah rawh.

Hetiang thil a lo thlen hian eng nge thleng? Chu ventricle dinglam chu zawi zawiin a inzawm a, a thim zual a, a inzawm tha thei lo. Chu chu thinlunga thisen pump theihna a chak lo tihna a ni.

A pawimawh ber chu, thau emaw fibrous tissue lo piang thar hian thinlung electrical signal a tibuai a ni. Chuvangin ARVD vei tam tak chuan heartbeat mumal lo (arrhythmias) an nei thin. Hei hi a hlauhawm hle thei a, a chhan chu rang taka cardiac arrest emaw thihna emaw a tipung a ni.

He ARVD hi `Arrhythmogenic Right Ventricular Cardiomyopathy` (ARVC) an ti bawk. A chang chuan veilam pawh a nghawng thei a, chuvangin `Arrhythmogenic Cardiomyopathy` (ACM) an ti bawk.

ARVD hi eng stage nge ni?

ARVD i neih chuan hun kal zelah stage engemaw zat a paltlang thei.

1. Concealed stage: Hetiang stage chhung hian symptoms i nei lo mai thei. Mahse, exercise i tih hian heartbeat mumal lo i nei thei. Mak tak maiin he stage chhunga test thenkhat tih hian engmah a dik lo tih a lang thei.

2. Electrical stage: Hetiang stage-ah hian ventricular arrhythmias i nei tam zawk. Tin , cardiac death nghal theihna chance i nei sang zawk bawk. ECG hian heng heart rhythm lama harsatna te hi a hmuchhuak thei a ni.

3. Structural stage: Hetiang stage-ah hian heart rhythm pangngai lo (ventricular rhythm) leh cardiac thih thut theihna a sang zawk. Imaging test, scan ang chi hian i thinlung insiam dan a inthlak danglam tih chiang takin a tarlang thei a ni.

He ARVD hian tute nge a nghawng ber?

Doctor-te chuan he natna hi thalai zingah an hmu tam ber.Chu chu tleirawl emaw, tleirawl puitling emaw zingah a ni. ARVD hi infiammi naupang thenkhat cardiac death rang tak thlentu nia hriat a ni bawk. Zirna thenkhatah chuan he natna hi mipaah ​​hian a tam zawk deuh niin an sawi .

A tam zia atanga thlir chuan ARVD hi natna awm lo tak a ni. Mi 1,000 zinga pakhat emaw, mi 5,000 zinga pakhat emaw a vei nia sawi a ni tlangpui. Chhungkaw zingah tu mahin an neih loh pawhin a thleng thei a, mahse chhungkuaah a kal fo thin.

ARVC natna lan chhuah dante chu engte nge ni? I fimkhur ang u!

ARVD hi a tir lamah chuan symptoms i nei lo mai thei a, mahse cardiac death nghal theihna a awm.

A lan chhuah dan tlangpui chu:

• Ventricular arrhythmias: Hengte hi a hlauhawm hle thei. Heng arrhythmias vei zinga a chanve vel ah chuan a rah chhuah chu thihna thlen thei emaw, thihna hnaih tak emaw a ni thei. Rhythm hman tlanglawn ber chu ventricular tachycardia a ni a, he natna vei zinga 77%-ah a awm thin.
• Supraventricular arrhythmias: A tam ber chu atrial fibrillation an tih hi a ni.
• Heart palpitations: Hei hi i rilru chhungah thil pakhat a rawn ri chhuak ang maiin a lang thei. Hei hi thinlung thawk dan pangngai lo vang a ni.
• Luak chhuak, lu hah emaw, muhil emaw: Hei hi thinlung thawk mumal lo vang pawh a ni.
• A rilru a na.
• Sudden cardiac death: Hei hi ARVD chhinchhiahna hmasa ber a ni thei.
• Thâwk a tawi.
• Ke, ke ruh, ke emaw, pum emaw a hring chhuak.
• Lung lam chak lohna.

Heng symptoms te hi kum 20 leh 50 inkar atanga tan a ni tlangpui a, Doctor te hian ARVD hi kum naupang tak atangin (kum 40 an tlin hmain an hmuchhuak fo thin).

ARVD awm chhante chu engte nge ni?

ARVD vei zinga 60% vel chuan genetic mutation an nei a ni. Zirchiangtute chuan he natna thlentu gene 13 tal an hmuchhuak tawh a ni.

Heng genes pangngai lo te hian heart muscle cell te inzawmkhawm leh inbiakpawhna atana puitu protein te chu a tichhia a ni. Hei hian ventricle dinglama heart muscle cells te chu a inthen a, a thi thei a ni. Hei hi a bik takin lungkhamna emaw, thawhrimna emaw lai hian a awm fo thei.

ARVD vei zinga 30% atanga 50% tal chu chhungkaw history nei an ni.Chuvangin, ARVD vei mi pakhat chhungte first leh second-degree (nu leh pa, unau, fate, tu leh fate, uncle, aunts, nephews, nieces) te chu doctor-in a enfiah tir a pawimawh hle. Natna lanchhuahna a awm lo a nih pawhin chhungte naupangte chuan damdawi lam thurawn an zawng tur a ni.

Researcher-te chuan ARVD-ah hian inheritance pattern pahnih an hmuchhuak a:

1. `Autosomal dominant`: Nu leh pa pakhat hian gene mutation a nei a. Chutiang chhungkuaah chuan naupangte hian he natna hi an rochun theihna chance 50% an nei a ni. Mahse, chhungkaw member hrang hrangah symptoms leh a lo lan kum a inang lo thei. ARVD hi geographical area thenkhatah a tam zawk a, Italy-ah te pawh a awm nasa hle.

2. `Autosomal recessive` (a tam vak lo): Nu leh pa pahnih hian gene mutation an nei a, mahse symptom an lantir lo. `Naxos natna` tih hi entirnan a ni. Vun pawn lam (`hyperkeratosis`) leh kutphah leh kephah sam sei tak, "wool-like" (`wool-like hair`) a siam bawk.

ARVD hi chhan dang vang pawh a ni thei:

• Ventricle dinglam atanga pianpui thil dik lo (congenital abnormalities) a awm.
• Viral emaw inflammatory `myocarditis` (thinlung ruh natna) emaw a ni thei.
• A chhan hmuhchhuah a la ni lo.

Engtin nge ARVD (Arrhythmogenic Right Ventricular Dysplasia) hi hriat theih?

I doctor chuan i medical history, taksa enfiahna leh test hrang hrang a zirin ARVD hi a hre thei a ni.

A hnuaia harsatna engemaw zat inzawmkhawm i neih chuan i doctor chuan ARVD a nei tih a hmu thei ang:

• Ventricle dinglam hnathawh dan dik lo.
• Ventricle dinglam heart muscle (`myocardium`)-a thau emaw fibro-fatty tissue emaw awm.
• `ECG/EKG` (Electrocardiogram) report pangngai lo tak a ni.
• Heart rhythm mumal lo (arrhythmias): Entirnan, supraventricular tachycardia, ventricular tachycardia, emaw ventricular fibrillation, a bik takin exercise neih laiin.
• Chhungkaw chanchin ARVD vei tawhna.

Heng thilte hi engzat nge i neih a zirin i doctor chuan "definite," "borderline," emaw "possible" emaw tih diagnosis a pe thei che a ni. Thil engemaw takah chuan, mahse a ni lo, i doctor pawhin genetic testing nei turin a refer thei che a ni .

ARVD hriat theihna atana test hmante chu engte nge ni?

• Electrocardiogram (ECG/EKG): Thinlung electric hnathawh dan enfiahna test a ni.
• Transthoracic echocardiogram: Hei hi thinlung ultrasound ang a ni. Thinlung chamber, valve leh pump theihna te a en thei a ni.
• `Holter monitor`: Hei hi `ECG` machine te tak te ang a ni a, darkar 24 atanga 48 chhung i bun thin. Nitin i thinlung thawk dan a record thin.
• Right ventricular angiogram: Hei hi hman a tlem hle.
• `Electrophysiology testing neih a ni` tih hi a ni.Thinlung electrical system-a harsatna awm leh awm loh enfiahna atana test bik.
• Cardiac magnetic resonance imaging (MRI): Hei hian thinlung thlalak chipchiar tak a siam thei a. Hei hi ARVD-a right ventricle-a thau awm ang chi thil hmuhchhuahna atan a pawimawh hle.
• `Cardiac computed tomography (CT):` Hei hi thinlung thlalak lak dan dang a ni.
• `Biopsy` (tissue sample lak): Hei pawh hi tih a tlem hle. Thinlung atanga tissue te tak te la chhuakin an enfiah thin.

ARVD enkawl dan tur chu engte nge ni?

Tunah hian ARVD hi damdawi a la awm lo. Mahse, i doctor chuan a hnuaia mi ang hian tih a tum ang:

• I thinlung rhythm mumal lo (`ventricular arrhythmias`) te chu control rawh.
• Thisen zam a veng tur a ni.
• I thinlung chak lohna chu enkawl rawh.

ARVD enkawlna hrang hrangte chu:

• Antiarrhythmic drugs: Hun rei tak chhunga thinlung thawk mumal lo leh/ emaw thihna nghal mai tur venna. Hei hi Doctor ten an hman tam ber a ni. Damdawi sotalol emaw amiodarone emaw te pawh an pe thei che a ni.
• Thisen sang damdawi: Damdawi, diuretics (taksa atanga tui tam lutuk paih chhuaktu) emaw, beta-blockers (thinlung hnathawh tur tihtlemtu) emaw ang chi.
• Anticoagulant (blood thinner): Thisen zawrh tur ven nan warfarin ang damdawi pek thin a ni.
• Radiofrequency catheter ablation: Heart rhythm mumal lo fo thin, damdawi hmanga control theih loh enkawlna a ni. Hei hian thinlung thawk mumal lo thlentu thinlung hmun tlemte tihchhiat a huam a ni.
• Implantable cardioverter-defibrillator (ICD): Thil te tak te, thih thut hlauhawma awmte thinlunga dah thin a ni. Heart rhythm hlauhawm tak a hriat chuan a hmuchhuak ang a, chu chu siamthat turin electrical shock chu thinlungah a thlen ang.
• Heart transplant: Hei hi enkawlna dang zawng zawng a hlawhchham hunah tih a ni. He natna vei zinga za zela tlemte chauh, 2% atanga 4% vel chauh hian thinlung thar an mamawh a ni.

I dam chhungin he natna hi enkawlna pakhat aia tam i mamawh mai thei tih hre reng ang che.

Enkawlna hian harsatna emaw, side effect emaw a nei em?

Ni e, enkawlna thenkhatah hian fimkhur tur thil engemaw zat a awm.

• Warfarin i ei a nih chuan thisen test neih fo a ngai ang . I doctor chuan dose dik tak i dawng tih a hriat chian a ngai ang. Test result a zirin i dose chu tihdanglam theih a ni.
• Catheter ablation enkawlna hi a tir lamah chuan mi tam tak tan hlawhtling mah se, hun kal zelah natna a zual zel avangin mi 60% vel chuan an heart rhythm irregularities hi a lo lang leh thei a ni.
• ICD device chhunga wire te hi a kal kual thei a, a thawk tha lo thei bawk a, chuvangin i check reng a ngai a ni.

Engtin nge ka in enkawl ang? Eng nunphung tihdanglamna nge mamawh?

I thinlung tih hahdam nan i nunphung eng emaw zat tihdanglam a pawimawh hle.

• Zu in hi tihtlem rawh.
• Zuk leh hmuam thil hman kha bansan vek rawh.
• Ei leh in hrisel (thau tlem, thei leh thlai tam tak ei) .
• Caffeine awmna ei leh in (coffee, tea, chocolate ang chi) hi tihtlem la.
• Taksa rihna dik tak vawng reng rawh.
• Taksa tihchakna hahthlak tak takte chu tihtlem rawh.

A pawimawh ber: Exercise i tan hmain doctor hnenah zawt fo thin ang che. Competitive sports hi a tha lo. Low-intensity sport hi a pawi lo mai thei.

I enkawlna chhung zawngin i doctor nen inbiak fo thin ang che. Damdawi dose dik tak i dawng tih an enfiah ang. Tin, regular follow-up appointment-a kal hian i dinhmun inthlak danglamna eng pawh chu a hmain i man thei bawk.

Risk hi tihziaawm theih a ni em?

Ni e, eng emaw chen chu. I chhungkuaa mi pakhatin ARVD a vei a nih chuan a rang thei ang bera screening neih hi i hlauhawmna tihziaawmna tha ber a ni. Test awlsam tak, natna nei lo hian heart rhythm pangngai lo nei thei tura hlauhawm i nih leh nih loh a hriattir thei che a ni. I nih chuan i doctor chuan i tana tha tur enkawlna ruahmanna siam turin a pui thei che a ni.

ARVD natna hi engzat nge dam rei?

ARVD dam rei zawng hi a hmuhchhuah hun azirin a inang lo. A tha ber chu a hma thei ang bera natna hriatchhuah a, lungphu mumal lo venna atana enkawlna lak hi a ni. He natna hi hun kal zelah a zual zel a.

ARVD enkawl loh chuan i right ventricle a fail thei. Tichuan i left ventricle pawh a fail thei bawk. Hei hian `heart failure` leh `atrial fibrillation` ang chi dinhmun a thlen thei a ni. Researcher-te chuan ARVD hian ventricle pahnih a nghawng chuan thil a chhe zawk niin an ngai.

Mahse, enkawlna hmang hian i thinlunga harsatna awm thei tihziaawmna tur leh heart attack hlauhawm tak tak laka invenna tur i mamawh tanpuina i hmu thei a ni. Zirna thenkhatah chuan mi thenkhat chu kum 65 an tlin hnuah he natna hi an vei tih hmuhchhuah a ni a, ARVC vei mi panga zinga pakhat velin kum 50 an tlin hnuah natna lanchhuahna an nei tan niin an chhut bawk a, chuvangin ARVC hmang hian dam rei tak hman theih a ni.

Tunlai hian CT leh MRI ang chi imaging technology hmasawn tak takte hian a hmaa hriatchhuah leh enkawl theih a nih avangin ARVD vei tan chuan hun rei tak chhunga thlirna a tha hle.

Amaherawhchu, natna hriat chhuah loh emaw, a tul anga enkawlna dawng lo emaw-ah chuan thihna thut tak a thleng thei a ni. ARVD hi kum 35 hnuai lam cardiac thih thut 11% leh infiammi zingah cardiac thih thut 22% thlentu nia sawi a ni.

Engtikah nge Doctor ka hmuh ang? Engtikah nge emergency room-ah ka kal ang?

ARVD i neih chuan i dam chhung zawngin medical checkup i neih chhunzawm a ngai dawn a ni.I doctor chuan enkawlna dik tak i dawng em tih enfiah fo a ngai ang. ICD i neih chuan enfiah fo a ngai ang .

Emergency-ah eng nge tih tur?

Mi pakhat a tlu thut a, i call a chhan loh chuan 1990 (Sri Lanka emergency ambulance service) chu call nghal rawh. Tichuan, a theih chuan CPR (cardiopulmonary resuscitation) tan la, a tlem berah kut hmanga CPR hmang tan rawh.

Sudden cardiac arrest hlauhawma i awm chuan in lama awmte chu CPR training neihpui a tha.

Doctor hnenah eng zawhna nge ka zawh ang?

• Exercise ka ti thei em, infiamnaah pawh ka tel thei em? A nih chuan eng ang infiamna nge?
• Eng enkawlna nge ka tan a tha ber?
• Hetih lai hian ICD ka mamawh em?

ARVD hi a lan chhuah hmain hriat a harsa thei a, chuvangin i chhungkaw chanchin hriat a pawimawh hle. Chhungkaw history-a natna vei avanga hlauhawm i nih chuan i doctor chuan a test thei che a ni.

Take-Home Thuchah a ni

Okay, chuti a nih chuan tunah chuan vawiin a kan sawi tawh kha i hrethiam tawh zawk a ni, ARVD. A tlem hle nachungin, thinlung natna khirh tak a ni thei. Genetic factors avanga lo awm a ni fo thin . Chuvangin i chhungkuaa mi tu emaw hian hetiang dinhmun hi a nei a nih chuan midang test tir a pawimawh hle.

Natna hi a hma thei ang bera hriatchhuah a, enkawlna dik tak dawng a, nunphung tihdanglamna tul tak tak siamin he natna hi i nunpui thei ang. I doctor nen inzawmna nei reng la, an thurawn zawm rawh. Tin, i hmangaih tak takte’n `CPR` an hriat chian chuan emergency-ah i nunna chhanhimna kawngah a pui thei bawk. Hlau suh, awareness hi chakna lian ber a ni!

` ARVD, Arrhythmogenic Right Ventricular Dysplasia, lung natna, lungphu chawl, cardiomyopathy, lungphu thih thut, thlah natna, thinlung natna