I doctor chuan nangmah emaw, i hmangaih tak emaw chu hnute cancer a vei tih a hmuchhuak em? Tichuan ‘chemotherapy’ tih thumal hi i hre tawh ngei ang. He thu i hriat hian tlemin hlauhna leh lungkhamna i neih hi thil pangngai a ni. Mahse heng enkawlna chungchang hi dik taka hriattir kan nih chuan , chu hlauhna chu nasa takin a tlahniam thei a ni. Chuvangin, chemo enkawlna atana hman damdawi class pawimawh ber pakhat chu anthracyclines an ti a ni. Vawiin hian he thu hi awlsam tak leh in hriatthiam theih tur angin kan sawi dawn a ni.
Engtin nge he damdawi hian taksa chhungah hna a thawh tak tak?
A awlsam zawngin sawi ila, anthracyclines hi antibiotic chi khat a ni a, cancer cells te tihlum thei a ni. Mahse, common cold emaw flu emaw atana kan ei thin antibiotics ang kha an ni lo. Anni hi leia awm, Streptomyces an tih fungus chi khat atanga siam an ni.
Cancer cell chu photocopy machine, thunun theih loha copy siamtu angin han ngaihtuah teh. He machine hian a copy sang tam tak a siam chhunzawm zel a ni. Hei hi tumor siam dan leh lo thanglian dan a ni. Anthracyclines te hian an tih chu chu copy machine chhunga DNA ‘master copy’ ah chuan an inzawm tlat a ni. Tichuan copy thar an siam thei tawh lo. Chumi awmzia chu cancer cell-te inthen darh leh chak taka an than theihna chu a tawp vek tihna a ni.
He damdawi hi injection angin emaw, vein (intravenous emaw IV emaw) chhunga saline solution angin pek thin a ni. I doctor chuan i cancer stage leh condition a zirin i enkawlna dose leh hun chhung chu a ruat ang.
A tam zawkah chuan hnute cancer a lo tan tirh lai hian a tumor lakchhuah nan operation an ti thin. Tichuan, taksaa cancer cell te tak te, hmuh theih loh , taksaa la awm reng thei zawng zawng chu tihchhiat vek turin chemotherapy pek a ni. Hei hi "Adjuvant Chemotherapy" kan ti a ni. Hei hian cancer lo awm leh theihna chance nasa takin a ti tlem a ni. Anthracyclines hi "Adjuvant Chemotherapy"-a hman tur damdawi chi hrang hrang zinga mi a ni.
Anthracyclines hi engtiang chiahin nge a thawh?
Zirna tam takah chuan anthracyclines awmna chemotherapy regimen hi a tel lo regimen aiin a hlawhtling deuh tih hmuhchhuah a ni.
Zirna lian tak pakhatah chuan, hnute cancer natna vei, a lo lang leh theihna sang tak nei hmeichhia 4,000 chuang chu group hnih-ah ṭhenin enkawlna pahnih an pe a ni.
1. Anthracycline chi hrang hrang (TaxAC): 1.1.Heng mite hi anthracyclines bakah chemotherapy damdawi dang pek an ni bawk.
2. Anthracycline-free group (TC): Heng mite hi anthracycline tel lo, chemotherapy damdawi combination danglam tak pek an ni.
Kum 3 vel zet group pahnihte hi an enfiah hnuah, zirchiangtute chuan cancer lo kir leh tawh lovin eng chen nge hrisel taka an dam theih tih an en a. A result chu hetiang hi a ni.
- Anthracycline (TaxAC) group-ah chuan cancer 92.4% chu a lo lang leh lo.
- Non-anthracycline (TC) group-ah chuan cancer 91.7% chu a lo lang leh lo.
Heng results te hian a danglamna lian tham lo mahse, anthracycline-containing therapy hian cancer lo awm leh theihna chu tlem a la tihziaawm thei tih a tarlang.
He enkawlna hian side effect a nei em?
Ni e, chemotherapy treatment dang ang bawkin anthracyclines hian side effect a nei thei a ni. Mahse mi zawng zawngin kan hmu vek lo va, tam tak chu thunun theih a ni. Hengte chungchangah hian i doctor chuan thurawn a pe thei ang che.
| Side effect chi hrang hrang | Symptoms awm thei te |
|---|---|
| Side Effects Mild atanga Moderate thlenga awm thei | |
| Thil awm dan tlangpui | Luak leh luak chhuak, khawsik leh khawsik, luak chhuak, pum na, taksa na, hah. |
| Vun leh nail te | Skin rash, itching, nail rawng danglam, vun rawng danglam. |
| Thil dang a nghawng dan | Mipa zun rawng danglam (reddish), anorexia, light sensitivity, thlasik chawlhsan, leh mipa sperm count tlahniam. |
| Thisen nena inzawm | Thisen chhuah, thisen var (white blood cells) tlahniam (chu chuan natna kai theihna a tipung a), ruhro (bone marrow) tihtawp a ni. |
Side effect na tak tak a awm tih hre reng ang che
Heng damdawi te side effect ber leh pawi ber chu thinlung tichhe thei a ni. Heng damdawi te hi rei tak hman a nih chuan heart failure ang chi condition a awm a, chu chuan heart muscle a tichak lo thei a ni. Tin, anthracycline thenkhat hian cancer chi dang, leukemia ang chi, a tlem hle a, a vei theihna chance tlemte chauh an keng tel bawk.
Heng hlauhawmna avang hian i oncologist leh cardiologist te chuan i enkawlna chhung zawngin i thinlung hnathawh dan an enfiah ang a, chu chuan chhiatna thleng thei zawng zawng chu a ti tlem thei ang. Chuvangin hei hi hlau suh.
Hengte hi hnute cancer chi hrang hrang tan a tha zawk em?
Awle. Hnute cancer zawng zawng hi a inang vek lo. Chuvangin i doctor chuan i tana tha ber tur a thlang ang. Hei hi thil engemaw zatah a innghat ang:
- Cancer natna stage
- Cancer hian hormone a sensitive em tih (Hormone-receptor status) .
- HER2 dinhmun chu cancer a ni
- Cancer hi lymph node-ah a darh tawh em tih
- I kum leh i hriselna zawng zawng
Entirnan, mi pakhat chu kum 60 chunglam, thisen sang nei, leh thinlung natna nei tawh a nih chuan doctor chuan anthracyclines telh loh enkawlna tur a rawt zawk a ni.
Research atanga a lan dan chuan cancer chi hrang hrang, triple-negative ang chi, aggressive tak tak nei te leh an cancer lymph node-a darh tawhte chuan anthracycline telna enkawlna hi an hlawkpui ber a ni.
Cancer hian anthracyclines a do thei ta a nih chuan eng nge thleng ang?
A chang chuan hun kal zelah cancer cell te hian heng damdawi te hi an do thei a, chu chu damdawi te hian hna a thawk lo tihna a ni. Hetiang hi a lo thleng a nih chuan lungngai suh. Chutiang a nih chuan i doctor-in a hman theih tur damdawi leh enkawlna dang engemaw zat a awm a.
Entirna thenkhat chu:
- Capecitabine (Xeloda) hman thin a ni.
- Eribulin (Halaven) chuan a rawn ti a.
- Gemcitabine (Gemzar) a tih hi a tha hle.
- Vinorelbine (Navelbine) tih hi a awm a.
- Tunlai damdawi antibody drug conjugate ang chi te
Enkawlna hmasawn tak tak pawh a awm a, chu chu targeted drug therapy leh immunotherapy te hi a ni. A pawimawh ber chu i medical team nena inbiakpawhna neih reng hi a ni.
Take-Home Thuchah a ni
- Anthracyclines hi hnute cancer atana hman thin chemotherapy damdawi class chak tak leh tangkai tak a ni.
- An hnathawh ber chu cancer cell DNA a nghawng a, an inthen darh leh an lo thang lian tur a titawp a ni.
- Damdawi zawng zawng ang bawkin side effect a awm bawk. A bik takin thinlunga nghawng a neih theih avangin damdawi lam enkawlna uluk tak hnuaia enkawl a pawimawh hle.
- Anthracycline pek i nih leh nih loh thutlukna chu thil tam tak ngaihtuah a nih hnuah siam a ni ang a, chu chu i cancer awm dan leh i hriselna dinhmun te hi a ni.
- I enkawl dan te, a nghawng tha lo te, emaw, zawhna, hlauhthawnna leh ngaihtuahna i neih te chu i doctor nen zalen taka sawipui hlau ngai suh. He indonaah hian hnehna chang turin awareness dik tak hi ralthuam tha ber a ni.
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