Doctor-te’n hnute cancer i vei tih an nemnghet khan i hlauhthawn zia, i mangang zia leh i lungngaih zia chu ka ngaihtuah thei. Chutiang hun lai chuan kan rilruah zawhna a lo lang tam em em a. Mahse i doctor-in ‘HER2-Positive’ tih ang thumal a sawi hian i rilru a ti buai zual ngei ang. "Chu thumal chu eng nge ni? Ka dinhmun hi a pawi tihna em ni?" Thil sangkhat rilruah a lo lang hi thil pangngai a ni. Chuvangin vawiin hian he ‘HER2-Positive’ hnute cancer hi eng nge a nih, eng nge a awmzia, a enkawl dan tur te chu i hriatthiam theih tur awlsam takin kan sawi dawn a ni.
'HER2' chu eng nge ni?
A awlsam zawngin sawi ila, HER2 hi protein a ni a, kan taksaa hnute cell te a lo thang lian thei a ni. A hming pum chu ``Human Epidermal Growth Factor Receptor 2`` tih a ni. He protein hi mi hrisel tak hnute cell-ah hian a tlem berah, controlled amount-in a awm a. Cell te chu mumal taka inthen darh leh thang lian turin a pui thin.
Mahse, hnute cancer thenkhatah chuan HER2 protein siamtu gene a chhiatna avang hian he protein hi a tam lutuk a siam chhuak thin. Car accelerator-a ke pen ang mai a ni. Tichuan, car chu chak taka kal ang maiin heng cancer cell te hi an inthen darh tan a, an thang chak hle a, thunun theih lohvin. Cancer a na zual chhan ber chu he protein siam chhuah tam lutuk hi a ni.
Chuvangin, i cancer chu ' HER2-positive ' a nih chuan i cancer cells chung lamah he growth protein HER2 an tih hi a tam lutuk tihna a ni.
Engtin nge HER2-positive a nih leh nih loh ka hriat theih ang?
Breast cancer i vei nia i rinhlelh hunah chuan i doctor chuan biopsy neih a rawt mai thei. I hriat reng angin, hei hian tissue tlemte la a, lab-a test turin thawn a huam a ni. Chumi hnuah he tissue sample hi enfiahin cancer chi dik tak hriat a ni.
He test-a kan en ber chu HER2 status hi a ni. Tin, thil pawimawh dang chu check a ni bawk. Chu chu cancer hian hormone a sensitive em tih hi a ni. Chu chu, cancer hi hormone `(Estrogen)` leh `(Progesterone)` vangin a lo thang lian em tih hi a ni. Heng zawng zawng hi a en hnuah doctor chuan i tana enkawl dan tur tha ber leh hlawhtling ber tur chu a rel thin.
Kan test tur hi tlem han sawifiah leh ila.
| Marker a ni | Chu chuan eng nge a sawi? |
|---|---|
| HER2 dinhmun | Cancer cell te hi HER2 protein an neih tam lutuk (positive) nge an neih loh (negative) tih an enfiah thin. Positive a nih chuan he protein hian cancer cell te chu a ti thang chak hle tihna a ni. |
| Hormone Receptor dinhmun | Cancer cell-te hian hormone estrogen emaw progesterone emaw receptor an nei em tih an en a. Hengte hi positive a nih chuan chu hormone te chuan cancer chu a tipung thei a ni. |
Heng test result hian cancer chi hrang hrang i neih dan a hril ang. Entirnan, HER2-positive emaw Hormone Receptor-negative emaw a ni thei. Heng thu zawng zawng hi i enkawlna tur ruahmanna siam tura pui turin a pawimawh hle.
Tute nge HER2-positive cancer vei? A hlauhawm em?
HER2-positive hnute cancer hi hmeichhiaah pawh mipaah a awm thei a, mipaah pawh a awm tlem hle. Hmeichhia kum 50 hnuai lam ah a tam zawk a, a chhan dik tak erawh hriat a la ni lo.
Tûnah chuan i rilrua zawhna lian ber: Hei hi a hlauhawm em?
Thudik tak chu HER2-positive cancer te hian an than chakna rate a sang deuh mai thei. Chumi awmzia chu heng cancer cell te hian an inthen darh emaw, an darh chak lutuk emaw a sang deuh tihna a ni.
Mahse, hlauthawng suh! Hei hi i hriat reng a ngai a ni. Ni e, he cancer chi hi a rang thei hle. Mahse tunlai hian a tana tha tak tak therapies tha tak tak leh targeted tak tak siam a ni ta. Chuvangin "fast" tih thumal hi hlauh tur a awm lo.
Enkawlna leh dam leh beiseina
Hei hi he thuziak ah hian chanchin tha ber a ni. Kum 20 vel kalta khan HER2-positive hnute cancer hi enkawl harsa leh pawi tak anga ngaih a ni. Mahse medical science a lo thang chho zel a, tunlai dinhmun hi a danglam vek tawh a ni.
Scientist te chuan he HER2 protein hnathawh hi target thei leh block thei damdawi bik engemaw zat an hmuchhuak a. Hei hi `` targeted therapy'' an ti a ni.)` tih a ni. A dik tak chuan heng damdawi te hi a tam lutuk HER2 protein-ah direct-in an kal a, cancer cell-te'n "a thang chak zawk" tura signal an dawn chu a tikhawlo a ni. Hei hi car tlan chak takah brake vuah ang mai a ni.
Heng targeted therapies te avang hian HER2-positive breast cancer vei chu tunah chuan a dam kim theihna chance a sang hle a, hormone-dependent cancer tam zawk damna rate nen a inang hle.
Enkawl hnuah eng nge thleng?
Enkawlna i zawh hnuah i doctor chuan a lo vil reng ang che. A tlem berah chuan cancer hi a lo let leh thei a, taksa peng dangah pawh a darh thei bawk. Chutiang a nih chuan i doctor chuan biopsy a ti leh ang. Hei hi a chhan chu cancer nihna hi a chang chuan hun kal zelah a danglam thei a ni. Entirnan, a hmaa HER2-positive cancer chu a lo kir leh thei a, HER2-negative a lo ni thei bawk. Chuvangin enkawl dan hi a dinhmun thar ber atanga thlir a ni fo thin.
Chuvangin, i hlauhthawnna chu paih bo rawh. Ni e, cancer tih thumal hi a hlauhawm hle. Mahse HER2 -Positive hi tunlai hian enkawl theih leh tihdam theih tak a ni.
Take-Home Thuchah a ni
- HER2-positive breast cancer chu cancer cell-te’n protein (HER2) an siam tam lutuk a, chu chuan an than chakna a ti chak a ni.
- He natna hi i biopsy atanga tissue sample enfiah atanga hriat theih a ni.
- Hetiang cancer chi hi tlem chuan a thang chak deuh thin a, mahse hlauh a ngai lo.
- Tunlai hian chutiang atana targeted therapies siam chhuah hlawhtling tak tak a awm ta. Chuvang chuan dam leh theihna chance a sang hle.
- Zawhna, hlauhthawnna, rinhlelhna i neih apiang chu i doctor nen zalen takin sawipui rawh. Chutah chuan thu dik ber leh hahdamna tha ber i hmu ang.
- Nangmah chauh i ni lo. Ngaihtuahna nghet leh enkawl dan dik tak nen chuan he harsatna hi i hneh thei a ni.
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