Hnute cancer chi hrang hrangte chu engte nge ni? (Types of Breast Cancer) A awlsam zawngin i hrethiam ang u

Hnute cancer i vei tih i hriat chuan hlauhna leh mangang i neih thin chu thuin sawi a harsa hle. I rilruah zawhna tam tak i nei a. "Engvangin nge hetiang hi ka chungah a lo thlen?", "Tunah eng nge ka tih ang?", "Hei hi tihdam theih a ni em?" He zinkawngah hian thil awlsam tak leh i hriatthiam theih tur tawng hmanga sawifiah ka tum a ni. Eng cancer chi nge i neih tih chiang taka hriat chu indona i tan hmaa hmelma hriatthiam ang mai a ni. Chu chu i tana tha tur enkawlna thlan hmasak ber leh pawimawh ber a ni.

Hormone Receptor-Positive hnute cancer a awm thei

Hei hi hnute cancer chi khat a ni ber. A tlangpuiin, hnute cancer 100 zinga 80 vel chu he category-ah hian an tel a ni.

Chuti a nih chuan he "hormone-dependent" hian eng nge a awmzia?

Ngaihtuah mai rawh. Kan taksa, a bik takin hmeichhe taksa hian pianphung atanga lo chhuak hormone pahnih estrogen leh progesterone -te a nei a. Hengte hi kan taksaa thil kalphung pangngai (normal process) atan a pawimawh hle. Mahse, cancer cell thenkhat chu heng hormone te hi an "addicted" hle a ni. Chu chu, heng cancer cell-te chung lamah hian heng hormone-te hi lo kal a, an nghet theihna tur "receptor" emaw kawngkhar emaw tlemte chauh a awm tihna a ni. Estrogen hormone a lo kal a, chu kawngkhar chu a kik chuan cancer cell chuan chuta tang chuan ei tur a dawng a, a lo thang lian a, a inthen tan ta a ni. Thlai tui i pek ang bawkin a lian zawk thin.

I medical report-ah `ER-positive` (Estrogen Receptor-Positive) tih a awm chuan i cancer cell-te chu hormone estrogen lakah an sensitive tihna a ni. `PR-positive` (Progesterone Receptor-Positive) a tih chuan hormone progesterone a sensitive tihna a ni. Chung zinga pakhatah pawh a sensitive a nih chuan cancer chu hormone receptor-positive cancer an ti a.

Hormone therapy hi operation hnuah emaw, chemotherapy emaw, radiation emaw hnuah cancer a lo let leh tawh loh nan pek thin a ni. Heng damdawi te hian cancer cell-te "kawngkhar" khar hmangin hna an thawk a, a nih loh leh taksain estrogen a siam loh nan an titawp bawk.

HER2-Positive hnute cancer a ni

Tunah chuan chi dang kan sawi leh ang. Breast cancer cell thenkhat (cancer zawng zawng zinga 20% vel) chuan an chung lamah protein bik HER2 (Human Epidermal growth factor Receptor 2) an siam tam lutuk a.

HER2 hi cancer cell chu "a thang chak zawk, inthen chak zawk" tura hrilhtu antenna te tak te angin han ngaihtuah teh. Cell pangngai chuan heng antenna te hi tlemte chauh a nei a. Mahse HER2-positive cancer cell hian heng antenna tam tak hi a nei a ni. Chuvangin heng cancer chi hrang hrangte hi a nasa zawk thei a ni .

Mahse hetah pawh hian thu lawmawm a awm. Science lama hmasawnna a awm tawh avangin tunah chuan heng HER2 antennae tak takte hi target leh tichhe thei "targeted therapies " a awm ta. Hengte hian HER2 nei tam lutuk cell chauh an hmuh a, an beih avangin cell pangngaiah chhiatna a tlem zawk a ni.

Chumi atana damdawi pek ber leh tangkai ber chu Trastuzumab (Herceptin) a ni. Hei hian cancer lo kir leh tawh lo turin nasa takin a pui a ni. Mahse, he damdawi hi ei hian thinlung emaw, lung emaw-ah nghawng engemaw zat a neih theihna a tlem hle. Chu chu lungngai suh , i doctor chuan a check reng ang.

"Triple-Negative" tih hi hnute cancer a ni

Hei hi chi thumna a ni. Hnute cancer zinga 10%-20% vel chu hetiang chiah hian an tla thin. "Triple-negative" emaw "triple negative" emaw an tih chhan i hria em?

A chhan chu heng cancer cell ah hian , .

1. Estrogen receptor (ETU) a awm lo .

2. Progesterone receptor (PR) a awm lo .

3. HER2 protein a tam lo.

Heng cancer cells te hian a hmaa kan sawi tawh target lian pathum te hi an neih loh avangin hormone therapy emaw, Herceptin ang HER2-targeted therapies emaw hian hna a thawk lo. Chuvangin enkawl chu a harsa deuh thei.

Hetiang chi hi operation, chemotherapy, leh radiation hmanga enkawl a ni ber . Mahse, tunah chuan hetiang chiah hian enkawlna thar a awm ta a ni.

• PARP Inhibitors: BRCA gene mutation nei tan damdawi Olaparib (Lynparza) leh Talazoparib (Talzenna) te hi hman a ni. Chungte chuan cancer cell-te insiamthat theihna a tikhawlo a ni.
• Immunotherapy: Atezolizumab (Tecentriq) ang damdawi te hian kan immune cells hmangin cancer cells te do turin a pui thin.

Hei zawng zawng hi a buaithlak deuhin a lang thei. Chu chu thil pangngai a ni. A pawimawh ber chu cancer chi hrang hrang nei mah la, tunlai hian a enkawl dan tur tha tak tak a awm tih hriat reng a ni. I doctor leh medical team te chuan i tan enkawlna tur ruahmanna tha ber siam turin an thawk ho ang che.