I fa chu a damlo fo em? Cyclic neutropenia a ni thei bawk.

I fa te hian thla tin ni khatah khawsik, hmui na, kawr na a nei em? Natna pakhat chu a reh a, kar hnih emaw kar thum emaw hnuah a lo kir leh chauh em? "Ka fa taksa hriselna a chak lo" tih i ngaihtuah mai thei. Ni e, chu chu a dik mai thei. Mahse he cyclical illness awm chhan hi thil awm lo tak a ni thei. Vawiin hian chutiang dinhmun pakhat, cyclic neutropenia chungchang kan sawi dawn a ni.

A awlsam zawngin, cyclic neutropenia chu eng nge ni?

Hei hi hrethiam tur chuan kan thisenah sipai pakhat chanchin kan hriat hmasak a ngai a ni. Chu sipai hming chu neutrophil . He neutrophil hi thisen var chi khat a ni a, natna laka min venghimtu, kan taksaa lut natna hrik, a bik takin bacteria te dotu a ni. Kan taksa chhunga sipai awm ang mai a ni.

Neutropenia chu thisen a neutrophil sipai awm zat pangngai aia hniam a nih chuan a ni. Sipai pakhat chu a sipai an tlem chuan a chak lo a, neutrophil a tlem chuan a chak lo ang bawkin kan taksa immune system a chak lo a, awlsam zawkin natna hrik kan kai tan thin.

Tunah chuan cyclic tih thumal awmzia hi han en ila. Cyclic tih awmzia chu "cyclical" tihna a ni. Chumi awmzia chu neutrophil level a hniam ngai lo tihna a ni. Schedule pangngaiah, cycle khatah a chho leh chho thin. A dik tak chuan, a tlangpuiin kar thum danah (ni 21 vel) , neutrophil level hi ni thum atanga ni nga chhung chu nasa takin a tlahniam thin. Tichuan a pangngaiin a kir leh a, chutah chuan kar thum chhung chu a tlahniam leh ta a ni. He cycle hi sawi lawk theih takin a thleng thin.

Hetiang dinhmun hi a tlem hle. Zirchiangtute chuan khawvel mihring maktaduai khat zinga pakhat chauhvin he natna hi an vei niin an sawi.

He natna lan chhuah dan engte nge ni?

He natna specialty chu neutrophil level tlahniam cycle angin a symptoms a lang chhuak thin. Chu chu, heng symptoms te hi neutrophils tlahniam atanga ni thum atanga ni li chhungin a lang a, neutrophil level a normal leh chuan symptoms te chu a bo ta a ni.

Heng symptoms awm dan hi dam chhungin a danglam thei a ni. Mi tam tak tân chuan puitlin an tlin chuan an natna lan chhuahna nasatzia chu a tlahniam a ni . Kawng na leh ha lama harsatna nei hi thalaite zingah a tam zawk a, lu na leh sinus infection (sinusitis) hi kum upa lam zingah a tam zawk thung.

Engvangin nge hetiang hi a lo awm?

Cyclic neutropenia hi genetic mutation avanga lo awm a ni . A chhan ber chu kan taksaa ELANE gene inthlak danglam vang a ni.

Gene hi kan taksa chhunga cell-te hnathawh dan tur hrilhtu thupek set angin han ngaihtuah teh. ELANE gene ah hian neutrophils te hnathawh thatna tura puitu enzyme siam dan tur thupek a awm a. He gene-ah hian chhiatna emaw, mutation emaw a awm chuan neutrophils te hi an thawk tha thei lo.

Hetiang dinhmun hi nu leh pa atanga fate hnena rochun a ni thei a , a nih loh leh nausen stage-ah a lo awm thei bawk.

He genetic defect avang hian .

• Taksa hian neutrophils a siam tling lo mai thei.
• Chutiang a nih loh chuan neutrophils te hi an thi thuai thei a ni.
• A nih loh leh neutrophils te hi an thawk tha lo thei bawk.

Doctor, engtin nge hei hi i diagnose?

Heng symptoms te hi pian tirh atanga hmuh theih a ni tlangpui a, chuvangin nausen lai atanga hriatchhuah a ni fo thin. He natna hi finfiah turin doctor chuan thil engemaw zat a ngaihtuah ang.

• Chhungkaw chanchin: Hei hi thlahtu a nih avangin chhungkaw dang (nu leh pa, unau) hian he natna hi an vei em tih enfiah thin a ni.
• Thisen test: Hei hi a pawimawh ber a ni. I doctor chuan i thisenah neutrophil level chu kar khatah vawi hnih atanga vawi thum vel kar ruk vel a enfiah ang . Hei hi i neutrophil level chu cyclically a tlahniam em tih enfiah nan tih a ni ang.
• Pattern of symptoms: Doctor chuan a lan chhuah tam dan (kar 3 danah vel) uluk takin a zirchiang ang. He cyclical pattern hian hei hi neutropenia chi dang aiin a thliar hrang thei a ni.
• Genetic testing: A châng chuan ELANE gene-ah hian mutation a awm leh awm loh finfiah nan genetic testing neih a rawt thei bawk.

He natna hi a hriat chian hunah chuan doctor chuan neutropenia chi dang, a lan chhuah dan inang, `Severe congenital neutropenia` (hmanlai chuan `Kostmann syndrome` tia hriat), `Autoimmune neutropenia`, leh `Idiopathic neutropenia` te chu a paih chhuak tur a ni.

Hei hi eng enkawlna nge ni?

Enkawlna kawngah hian tum lian tak pahnih a awm a. Pakhat chu hri kai awmsa tihdam a ni. A dang chu neutrophil level tihsan leh nakin lawka hri kai tur venna a ni.

Enkawlna hian side effect a nei em?

G-CSF enkawlna hian side effect tenau te a thlen thei. Mahse, doctor-te chuan he natna hi dose tlemte chauhvin an enkawl tan tlangpui a, chuvangin a side effects a tlem hle.

• Lu na
• Ruh leh ruhkawr natna
• Nausea leh luak chhuak

Hetiang thil hi a thleng thei a ni. I enkawl dan leh a side effects chungchang hi doctor nen uluk takin sawipui rawh.

Engtik hunah nge doctor ka biak ang?

Nang emaw i fa emaw hian cyclic neutropenia i nei a nih chuan, natna hrik i hmuh veleh damdawi lam thurawn lak a pawimawh hle .

Heng chhinchhiahnate hi i hmuh chuan doctor pan nghal rawh. A tul chuan Emergency Department (ETU) ah kal hreh suh.

Hri kai laka inven nan eng nge kan tih ang?

Infection laka invenna bakah hian i neutrophil count a tlem lai pawhin fimkhur a ngai bawk.

• I kut chu uluk takin silfai fo ang che, a bik takin chaw ei hma leh toilet hman zawhah.
• Kawng hriselna tha tak vawng reng rawh. Nitin ha silfai la , ha enkawltu pawh hmu fo ang che .
• Vaccine pek tura rawtna zawng zawng chu a hun takah la vek rawh.
• Kut sil lovin i hmai, mit leh hnar khawih loh tur.
• I damdawi ei tur chu i doctor-in a tih ang chiah chiah ei la, i thisen test pawh a hun takah tihsak rawh.

He natna hi dam chhung zawng ni mah se, G-CSF ang chi enkawlna hlawhtling tak takte chuan tunah chuan cyclic neutropenia vei tam tak chu nun pangngai takin an hmang thei ta a ni Pawimawh tak chu neutropenia chi dang thenkhat chuan cancer vei theihna a keng tel a, chu chu leukemia te hi a ni a, cyclic neutropenia erawh chuan a nei lo.