Kan taksa pum puiah thisen a luang chhuak tih kan hre vek a ni lawm ni? He thisen hi thisen kalna kawng (blood vessels) an tih, tui pipe ang maia awm, tube network kal tlang mai mai a ni lo. Chuvangin heng tube chhungril hi eng ang nge a nih tih i ngaihtuah ngai em? Vawiin hian chu tube chhunga line siamtu cell layer mak tak, te tak te tak tak chungchang kan sawi dawn a ni. Hei hi ‘endothelium’ kan ti a ni. Hei hi lining mai ni lovin, i taksa pum hriselna tichhe thei hna pawimawh tak tak tam tak thawk thei cell te tak te system a ni.
A awlsam zawngin, he endothelium hi eng nge ni?
I taksaa thisen kalna kawng tinreng chu mural ang maia sei tak, hrual hrual, cell khat chauh thuk, mural ang maia inzawm vek niin han ngaihtuah teh. Chu chu endothelium a ni. Cell chi khat bik endothelial cells an tih atanga siam a ni.
He endothelium tho hi i taksa chhunga heng hmunah te hian a awm a:
- Arteries: Thinlung atanga taksa peng dang panna thisen kalna kawng lian tak tak.
- Veins: Taksa atanga thisen phur let leh thin thisen kalna kawng a ni.
- Capillaries: Thisen kalna kawng te tak te, te tak te tak te an ni.
- Lymph capillaries: Kan lymphatic system-a tel ve vessel.
Bang mai a ni lo. I thisen leh i taksa tissue dangte inkara information leh nutrients inthlengna hmunpui ber angin a thawk a ni. A pawimawh em em a, tunah chuan scientist te chuan endothelium hi kan taksa peng lian ber pakhatah an ngai ta a ni. Ni e, organ a ni a, thin leh thinlung ang bawkin.
Endothelium hian kan taksa tan eng service nge a pek?
He cell layer te tak te hian hna a thawh hi mak tak a ni. A bulpui thenkhat han thlir ila.
Thisen kalna kawng (contraction and dilation) a control thin
I thisen kalna kawngte chu a tul hunah a zau (vasodilate) a ngai a, a tul hunah a tawi (vasoconstrict) a ngai bawk. Hei hi endothelium hian a thunun a ni.
Hetiang hian han ngaihtuah teh.
- Exercise i tih hian: I taksa ruhte hian thisen leh oxygen a mamawh tam zawk. Endothelium hian chu lai hmuna thisen kalna kawngte chu tizau turin signal a thawn a, chu chuan thisen chu awlsam zawkin a kal thei a ni.
- Ni lum takah: I taksa lumna humhim i duh a. Hei hian i kut leh kea thisen kalna kawngte chu a tikhawtlai deuh a, chu chuan i taksa peng lian ber berteah thisen a kal zel theih nan a pui a ni.
Chutiang chuan i thisen sang control-na kawngah leh taksa peng zawng zawngin thisen mamawh zat an dawn theih nan nasa takin a pui a ni.
Thisen atanga tissue-a tui kal zat a enkawl
Endothelium hi filter ang mai a ni. Thisen atanga nutrients leh oxygen te chu tissue-ah a kal tlang tir a, chutih rualin thisenah thil tha lo leh toxin lut lo turin venhimna hna a thawk bawk. Mahse, infection i neih chuan kan immune cells te hi thisen atanga chhuakin infection awmna lam pan a ngai a ni. Tichuan endothelium ngei pawhin chu cell-te chu chutah chuan an thlen theihna tur kawng a hawng ta a ni.
Thisen zam (Thrombosis) a veng thei .
A tlangpuiin thisen kalna kawng chhunga thisen zam hi a hlauhawm hle a ni lawm ni? Heart attack leh stroke ang chi natna khirh tak tak a thlen thei a ni. Endothelium hrisel chuan nitric oxide ang chi chemical bik a tichhuak a, chu chuan thisen tui a vawng reng a, a tul lo taka thisen a tikhawlo thei lo.
Endothelium hi engzat nge a lian? Kan taksaah khawiah nge a awm?
Miin i thinlung khawiah nge a awm tih a zawh che chuan i rilru i kawhhmuh thin. Miin i thluak awmna a zawh che chuan i lu lam a kawhhmuh thin. Mahse mi pakhatin endothelium awmna hmun a zawh che chuan i taksa peng eng pawh i kawhhmuh thei a ni. Taksa pumpuiah a darh zau em em a ni.
Ngaihtuah teh, mi pangngai thisen kalna kawng zawng zawng hi a tawp atanga a tawp thlenga dah vek ni ta se, kilometer 100,000 vel a sei a ni ang! Chu chu khawvel hmun hrang hranga vawi hnih fang kual tur chuan a tam zawk. Tin, he sei zawng zawng hi he endothelium hian a khuh vek bawk. A area i lak chuan tennis court engemaw zat aiin a lian zawk tlangpui. Tin, he system pumpui hi endothelial cell tluklehdingawn khat (1,000,000,000,000) chuang atanga siam a ni bawk.
Endothelial Dysfunction hi eng nge ni?
Hei hi kan ngaihven vek tur pawimawh ber a ni. ‘Endothelial Dysfunction’ tih awmzia chu endothelial cells te a chhiat avangin an hna a thawk tha thei lo tihna mai a ni. Kawngpui pakhata asphalt a tlakchhiat ang mai a ni a, lirthei tlan a harsa hle.
Hetianga endothelium chak lohna hi natna hlauhawm tak atherosclerosis , artery wall-ah thau a lo awm khawm a, thisen kalna kawng a tikhawlo thin , a hmasa ber a ni.
| Endothelium tichhe thei hmêlma lian ber berte | Eng thil nge thleng? |
|---|---|
| Thisen sang (Hypertension) 1.1. | Pressure sang taka thisen a luang chuan endothelial cells te chu a chhe vek a, pipe atanga tui tlan chuan a chhung lam a tichhe thei ang bawkin. |
| Cholesterol sang (Hyperlipidemia) 10. A rilru a hah lutuk chuan a rilru a buai em em a. | A bik takin cholesterol "bad" (LDL) a san chuan heng endothelial wall chhia te hi a innghat tan thin. |
| Zunthlum (Diabetes Mellitus) natna a ni. | Hun rei tak chhung thisen sugar level sang hian endothelial cells direct-in a tichhe thin. |
| Meizial zuk | Cigarette meikhua chemical tha lo sang tam takin endothelium chu a bei a, a hnathawh a tichhe vek a ni. |
| Exercise neih loh leh thau lutuk | Taksa tihchak loh leh thau lutuk avanga taksaa inflammation rei tak awm hian endothelium a tichhe thin. |
| Infection na tak tak a awm | COVID-19 ang chi natna khirh tak tak leh sepsis ang chi dinhmunah chuan endothelium hi nasa takin a chhe thei a ni. |
Endothelium ngei pawh a chak loh chuan eng nge thleng?
Endothelium a chhiat chuan a hrual hrual chu a hrual ta a ni. Chumi hnuah chuan cholesterol tha lo (LDL) chu chutiang hmun hrual takah chuan a pung tan ta a ni. Chumi chhanna atan chuan taksa immune system atanga cell te chu an lo kal a, chutah chuan an inkhawm thin. Heng zawng zawng hi a pung khawm a, hun kal zelah ‘fatty layer’ (plaque) a siam ta a ni.
He thau layer hi a lo lian chhoh zel chuan thisen kalna kawng chu a chhung atang chuan a tawi chho zel a. Hei hian thisen kal dan a tikhawlo a ni. Ni khat chu he thau layer hi a puak a nih chuan chu hmunah chuan thisen zam a lo awm thei a, thisen kalna kawng chu a titawp vek thei a ni.
Chuvangin, endothelium chak lo nei chuan a hnuaia risk factors te hi a tawk thei a ni.
- Lung natna
- Thai
- Coronary artery natna a ni
- Peripheral artery natna a ni
- Kal natna
- Insulin laka invenna a ni
Chuti a nih chuan engtin nge he endothelium hi kan hrisel theih ang?
Thu lawmawm tak chu he endothelium hlu tak hi kan nunphung thlak danglamin kan humhim thei tih hi a ni.
A awlsam zawngin kan taksa hian thil tha lo chi khat ‘free radicals’ an tih chu a siam chhuak thin. Chungte chuan kan endothelial cells te a tichhe thin. Heng thil tha lo tak takte tihbo nana puitu thil tha te hi ‘antioxidants’ an ti a. Chuvangin kan tih tur chu antioxidant tamna ei tur ei hian free radicals siam chhuah tihtlem hi a ni.
Thil tha tih tur
Antioxidant tamna ei tur ei tam rawh.
- Thlai dum hring: spinach, kale, collard greens te.
- Thlai leh thei rawng hring: tomato, carrot, beet, bell pepper, orange, grapefruit.
- Thlai chi hrang hrang: brown rice, oats, leh millet te.
- Hriselna atana hman tur hriak: olive oil, avocado.
Hetiang ei leh in (e.g., Mediterranean diet) chungchang hi i doctor nen in sawi dun thei a, i duh angin i thlak danglam thei bawk.
Thil tha lo pumpelh tur
Heng thilte hian i taksaah free radicals a tipung a.
- Meizial zuk: Hei hi hmelma number one a ni. Vawiin hian chawlhsan rawh.
- Sugar leh sweets tamna ei tur: Hengte hian taksaah inflammation a tipung a.
- Processed foods: Hengte hian thau leh chemical tha lo tak tak a pai thei.
- Stress lutuk.
- Mut tam loh vang.
Tin, exercise neih reng hi endothelial health atan a pawimawh hle bawk. Exercise i tih hian nitric oxide siamchhuah a pung a, chu chuan i thisen kalna kawng a ti hrisel a ni. Ni khata minute 30 vel kal ang chi thil awlsam tak pawh hian danglamna nasa tak a thlen thei a ni.
Thisen sang, zunthlum, cholesterol ang chi damdawi lam harsatna i neih tawh chuan i doctor-in a enkawl dan tur dik taka zawm a pawimawh . Heng damdawi te hian a tum ber chu heng dinhmunte hi control a, i endothelium chhiatna tih tlem a ni.
Take-Home Thuchah a ni
- Endothelium hi hmuh theih loh, mahse chak tak, i thisen kalna kawng chhunga awm cell layer pawimawh tak a ni.
- I thinlung leh thisen kalna kawng hriselna chu he endothelium hriselnaah a innghat a ni.
- Thisen sang, cholesterol sang, zunthlum, a bikin meizuk hi hei hi a hmelma ber an ni.
- He taksa peng hlu tak hi thlai leh thei thar tamna ei leh in hrisel ei hian i humhim thei a, exercise i tih fo bawk.
- I hriselna fimkhur la, damdawi lam enfiah fo la, damdawi lam harsatna i neih chuan doctor rawn la, inenkawlna mumal zawng rawh.
💬 Comments (0)
Comment a la awm lo. Hetah hian i comment hi a vawikhatna atan add rawh.
I comment kha add rawh